• Journal of the Korean Society of Food Culture
• /
• v.30 no.6
• /
• pp.766-772
• /
• 2015

This research was conducted to investigate the effect of essential oil (EO) from Artemisia Princeps Pampanini on quality of tomato during storage. EO was extracted by steam distillation and diluted by 1 and 2%. Total phenolic contents and antioxidative activities of EO were analyzed. Tomato was packaged corrugated box covered with polypropylene (PP) film containing EO (1 and 2%) and then stored at room temperature for 10 days. During storage, appearance, weight loss rate, soluble solid contents, pH and a (redness) value were measured for tomato. Total phenolic contents of EO increased in a dose-dependence. The DPPH and ABTS radical scavenging activities also showed a concentration-dependent increase. The weight loss rate was lowest using the film packaged in 1% EO. During the storage period, soluble solid contents and pH increased in all treatments. The a value increased regardless of EO concentration in films. Especially, tomato packaged with EO film showed a lower a value than non EO-packaged ones. This result suggests that application of EO to film is effective for tomato quality preservation.

• KOREAN JOURNAL OF CROP SCIENCE
• /
• v.49 no.spc1
• /
• pp.169-175
• /
• 2004

동의보감에 수재되어 있는 약쑥은 식용뿐만이 아니고 한방에서는 출혈 및 지혈약으로 자궁출혈, 임신중의 출혈, 코피지혈 등에 효과가 크다고 알려져 왔다. 또한 부인병과 건위, 설사치료와 항암활성, HeLa cell에 대한 억제작용도 보고되어 있다. MeOH엑스가 HCl-EtOH유발법, $1\%$ 암모니아 수용액 유발법, HCl-aspirin 유발법등에 의하여 유발된 위 손상에 대하여 강한 억제 작용을 나타내고 있는데 이는 flavonoid의 일종인 eupatilin으로 확인된 바 있다. 이 물질이 5-lipoxygenase inhibitor ($ID_{50}=14{\times}16^{-6}M$) 작용과 prosta glandin synthase의 활성을 약간 억제한다고 보고되었다. 약쑥의 eupatilin과 jaceosidin을 분리하여 그 화학구조를 구명하였다. 이를 지표물질로 하여 HPLC 분석조건과 HPLC용 검체의 조제, 표준검량선을 작성하였다. 강화사자발쑥 100 g의 잎에는 eupatilin은 240 mg, jaceosidin은 10 mg함유되어 있고 싸주아리쑥에는 eupatilin은 330 mg, jaceosidin은 123 mg 함유되어 있음이 확인되었다.

• FLOWER RESEARCH JOURNAL
• /
• v.18 no.2
• /
• pp.98-109
• /
• 2010

78 Korean native plants, which have not been used in general, were selected to be used as outdoor pot plants for three seasons, from spring to autumn. Plants, which were explored in about 30 places of Korea from 2007 to 2009, were transplanted to or sown in white plastic general pots ($27.5cm({\Phi}){\times}27.5cm(H)$) and hanging pots($28cm({\Phi}){\times}13cm(H)$) and grown in the garden of 36''56' latitude(N) and 127''09' longitude(E). 38 species(13 families and 29 genus) were suitable for outdoor general pots, and 46 species(28 families and 43 genus) for outdoor hanging pots. Among 38 plants for outdoor general pots, the principal species, which were easy to grow and have not been used in general, were 16 species, Metaplexis japonica in Asclepiadaceae, Phyteuma japonicum in Campanulaceae, Artemisia capillaris, Artemisia princeps, and Artemisia selengensis in Compositae, Carex humilis in Cyperaceae, Pennisetum alopecuroides, and Setaria viridis in Gramineae, Agastache rugosa, Glechoma hederacea, Elsholtzia splendens, Isodon inflexus, and Mosla punctulata in Labiatae, Vicia villosa in Leguminosae, Piper kadzura in Piperaceae, and Rosa multiflora var. multiflora in Rosaceae. Among 46 plants for outdoor hanging pots, the principal species, which were easy to grow and have not been used in general, were 17 species, Metaplexis japonica in Asclepiadaceae, Ixeris stonlonifera in Compositae, Calystegia japonica and Quamoclit angulata in Convolvulaceae, Dioscorea batatas in Dioscoreaceae, Glechoma hederacea and Thymus quinquecostatus in Labiatae, Trifolium lupinaster for. alpinus and Vicia villosa in Leguminosae, Menispermum dauricum in Menispermaceae, Piper kadzura in Piperaceae, Clematis mandshurica for. lancifolia in Ranunculoideae, Rosa multiflora var. multiflora and Potentilla fragarioides var. major in Rosaceae, Paederia scandens and Rubia akane in Rubiaceae, and Parthenocissus tricuspidata in Vitaceae.

• KOREAN JOURNAL OF CROP SCIENCE
• /
• v.49 no.6
• /
• pp.452-456
• /
• 2004

Artemisia Herb is the dry aboveground part of Artemisia asiatica (Compositae). This is listed officially in the Korean Herbal Pharmacopoeia and used mainly in stopping all kinds of bleeding, regulating menses and curing menstrual disorders as well as in alleviating pain. Eupatilin and jaceosidin were isolated from Sazabalsuk and Sajuarisuk. and identified by means of spectral methods $(UV,\;^1H\;and\;^{13}C-NMR,\;MS) $ and quantitative analysis using HPLC. Regression equations for two flavonoid component standards obtained from Artemisia asiatica were $y=76069_x\;+\;107329\;(r=0.9999^{**})$ for eupatilin, $y=76651_x\;+\;77399\;(r=0.9996^{**})$ for jaceosidin. The eupatilin content of Sazabalsuk was 240mg, jaceosidin was 10mg in 100 g dry leaves. The Sajuarisuk were 330mg, 123mg in 100g dry leaves, respectively.

• Korean Journal of Medicinal Crop Science
• /
• v.16 no.5
• /
• pp.326-331
• /
• 2008

To search for immunoactive natural products exerting anti-inflammatory activity, we have evaluated the effects on the water extracts of Artemisia princeps Pampanini (APP) on lipopolysaccharide-induced nitric oxide (NO), tumor necrosis factor-$\alpha$ (TNF-$\alpha$), and prostaglandin $E_2$ ($PGE_2$) production by RAW 264.7 macrophage cell line. Our data indicate that this extract is a potent inhibitor of NO production and it also significantly decreased PGE2 and TNF-$\alpha$ production. Consistent with these results, the protein and mRNA expression level of inducible NO synthase (iNOS) and cyclooxygenase-2 (COX-2) was inhibited by water extracts of APP in a dose-dependent manner. These results suggest that APP may exert anti-inflammatory and analgesic effects possibly by suppressing the inducible NO synthase and COX-2 expressions.

• Journal of Life Science
• /
• v.31 no.8
• /
• pp.736-744
• /
• 2021

Artemisia princeps Pampanini is an herbal medicine widely used to immune function-related diseases, such as anti-oxidative, anti-inflammatory, and antibacterial agents. In this study, we investigated the anti-inflammatory effects of AP extract and underlying mechanisms were evaluated in RAW 264.7 cells. The effects of AP extract were also studied in a complete Freund's adjuvant (CFA)-induced arthritis and lipopolysaccharide (LPS)-induced inflammation mouse model. In RAW 264.7 cells, AP extracts significantly inhibited the LPS-induced nitric oxide (NO) production and inducible NO synthase and cyclooxygenase-2 protein expression. The LPS-induced phosphorylation of mitogen-activated protein kinases and nuclear factor-κB was also significantly blocked by AP extract in RAW 264.7 cells. Oral administration of AP extract suppressed the increase in mouse paw edema and spleen index compared to CFA-treated mice group. Histologically, the infiltration of inflammatory cells was increased in cartilage and synovium in the CFA-treated mouse group, whereas it was suppressed in the AP extract-administered group. Furthermore, AP extract treatment significantly reduced the inflammatory cytokine, tumor necrosis factor-α, levels in CFA and LPS-treated mouse. In conclusion, the anti-inflammatory and anti-arthritis effect of AP extract was confirmed in both in vitro and in vivo models, suggesting that Artemisia princeps Pampanini may be a candidate material for arthritis treatment.