• The Journal of Internal Korean Medicine
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• v.30 no.4
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• pp.832-844
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• 2009

Objectives : This study was to observe the nephroprotective effects of the traditional prescription, Taeksa-san(TSS). TSS has generally been used for treating various renal diseases, including renal failure. Methods : Three different dosages of TSS extract were orally administered once a day for 28 days, At the 23rd day after TSS extract treatment, cisplatin was also treated. Then, 5 days after cisplatin treatment, all the rats (6 groups of 8 rats each) were sacrificed. Changes in the body weight, kidney weight, serum BUN and creatinine levels were observed with changes on the kidney MDA and GSH contents. The results were compared with captopril 100mg/kg, of which the effects on cisplatin-induced acute renal failures are already confirmed. Results : Dramatic decrease of body weight, increase of kidney weight, increase of serum BUN and creatinine levels were detected in the cisplatin control as compared with the intact control. In addition, marked increase of kidney MDA contents and decrease of kidney GSH contents were also detected in the cisplatin control as compared with the intact control. This means that cisplatin-induced ARF is induced by oxidative stress and related lipid peroxidation in the present study. However, these ARFs and inhibition of antioxidant effects induced by cisplatin were dose-dependently reduced by treatment with all three different dosages of TSS extracts. Conclusion : This study suggests that TSS extracts show favorable effects on cisplatin-induced rat ARF.

• The Korean Journal of Pesticide Science
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• v.18 no.4
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• pp.439-442
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• 2014

Cinnamyl derivatives are abundant secondary metabolite in biomass, and they have been studied on their biological activities. However, little information was available for plant growth regulation of the cinnamyl derivatives. In here, the acid, amide, alcohol, aldehyde and ester of cinnamyl derivatives were screened for their root growth inhibition properties including germination. The aldehyde, amide and ester derivatives showed better the root growth inhibition than the carboxylic acid, and the meta-positioned electron withdrawing group on cinnamyl derivatives enhanced the inhibition activity. 3-Chlorocinnamic acid, cinnamaimde and 4-methoxycinnamaldehyde were highlighted with the early stage root development inhibition ($GR_{50}$ < 100 mg/L) on Brassica campestris.

• Microbiology and Biotechnology Letters
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• v.35 no.1
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• pp.26-29
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• 2007

Tautomycetin (TMC), which is produced by Streptomyces sp. CK4412, is a novel activated T cell-specific immunosuppressive compound with an ester bond linkage between a terminal cyclic anhydride moiety and a linear polyketide chain bearing an unusual terminal alkene. Antifungal activity against Aspergillus niger and TMC productivity assayed by HPLC using culture extracts from Streptomyces sp. CK4412 grown on solid medium adjusted at various pH were measured. The cells cultured at acidic pH (pH 4-5) medium exhibited much stronger antifungal activity as well as higher TMC productivity than those cultured at neutral pH medium, implying that the acidic pH-shock should be an efficient strategy to induce the productivity of secondary metabolites in Streptomyces culture.

• KSBB Journal
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• v.14 no.6
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• pp.665-671
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• 1999

In this study, enhanced production of 10-deacetylbaccatin III(10-DAB), a precursor of taxol in semisynthesis, was investigated in Taxus cuspidata cell suspension cultures. The effects of initial inoculum size and sugar concentration were examined to prove the relationship between the production of 10-DAB and cell growth. The cell growth was found to be stimulated in Schenk and Hildebrandt(SH) medium. The lower the inoculum size as well as initial sugar concentration, the faster the cell growth rate. When the initial sugar concentration was dept low, the production of 10-DAB into medium was increased. By using perfusion culture, continuous cell growth was possible until the end of culture and more than 34.67 g/L of cell concentration could by obtained. This is about 2.5 times higher level than that of control batch culture.

• Fashion & Textile Research Journal
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• v.13 no.6
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• pp.877-887
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• 2011

The purpose of Sassanian dynasty was to succeed the civilization of Achaemenid dynasty but it shows vestiges of Parthian civilization in many ways. This study is an attempt to take a look at Sassanian civilization through analyzing these rock reliefs since these features are shown on the rock relief of Ardashir I in early Sassanian Iran. The way carried out this study was first, to collect and search documentary data to establish the theoretical background, and collect positive data by exploring this region and then we comparatively analyzed the two data in general and the result is the following: The form of costume is different according to the person's status. In the early period of Ardashir I the costume style of the royals is reflected by clothes such as tunic, trousers in parthian style. However, trousers do not have vertical pleats which are commonly shown in the case of parthian trousers. It assumed that after the early period of Ardashir I, Sassanians formed their own styles. The form of cap is also different according to the person's status. Ardashir I and the Ahura mazda god put on crown and Korymbos which symbolized the sovereign power. Except the king and the god, the prince and the king's vassal put on high caps called Kolah. Diadem which symbolized sovereign power of king was used by the king, the god and the crown prince. There are two kinds of diadem. The first form has vertical pleats and the other does not have pleats. This form became different depending on the social position. The form of hairstyle is generally thick curly hair which goes down until the shoulder. There is no difference in their hairstyle in terms of the social position. The beard style is generally in the form of scoop. There is also no difference in terms of the person's status.

• Clinical and Experimental Pediatrics
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• v.49 no.7
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• pp.796-799
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• 2006

Multicystic dysplastic kidney and congenital cystic adenomatoid malformation of the lung are independent disorders, but both result from abnormal morphogenesis during embryogenesis. Congenital cystic adenomatoid malformation of the lung is associated with renal anomalies as well as other extrapulmonary anomalies and almost all cases with these anomalies are stillborn. We report a case of a 21-month-old male who was admitted with the impression of acute infectious gastroenteritis; multicystic dysplastic kidney with congenital cystic adenomatoid malformation of the lung was detected incidentally during evaluation.

• Clinical and Experimental Pediatrics
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• v.50 no.3
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• pp.306-310
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• 2007

Restrictive dermopathy is a rare autosomal recessive disorder in which rigidity or tautness of the skin from the second trimester causes a fetal akinesia deformation sequence (FADS) and early death. Characteristic features include taut skin with prominent subcutaneous vessels, widely open fontanelles and cranial sutures, distinctive facies, flexion contractures, pulmonary hypoplasia, sparse eyelashes and and eyebrows, thin dysplastic clavicles. The histologic abnormalities of the skin are located in a thin dermis, consisting of compactly arranged collagen fibers, scanty elastic fiber. The dermoepidermal junction is flat, and epidermal appendages are absent, miniaturized or immature. The presence of adipose tissue may be increased. We report on the first Korean case of restrictive dermopathy with typical clinical features and histological findings.

• Korean Journal of Organic Agriculture
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• v.25 no.2
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• pp.489-498
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• 2017

This study was conducted to compare the mortality number of swine between before and after HACCP implementation on swine farm. Also, we analyzed the reason for implementing HACCP system, advantage and disadvantage of HACCP system implemented swine farm. The study was carried out by randomly selected fifty swine farms located in all around Korea. The results were as follows: The mortality number of swine before HACCP system was found to be 288.30, 122.90, 91.08, 18.22, and 108.10 in respiratory, diarrhea, abortion (stillbirth), an accidental death and others, respectively. However, after HACCP implementation, it decreased, without significantly, to 261.60, 101.10, 85.91, 16.37, and 108.60, respectively. Therefore, Therefore, the total number of mortality pig decreased from 628.70 (before HACCP) to 573.60 (after HACCP). The enhancement of farm competitiveness (26.92%) and hygienic and safety pig production (23.43%) were ranked as the first and second proposes for implementing HACCP system on swine farm. The major advantage of implementing HACCP were improvement the farm sanitation management level (20.90%) and the major disadvantage was surveyed as HACCP records (23.10%). We are expecting that our results might be used for producing safer livestock products by improving livestock products HACCP policy.

• Journal of the Mineralogical Society of Korea
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• v.24 no.2
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• pp.133-143
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• 2011

In Mujoo area, the granitic pegmatites are developed in the granitic gneiss complex with Jurassic gneissic granites, where Nb-Ta mineralization were reported. Pegmatites are mainly composed of large crystals of quartz, feldspars of end-member orthoclase and albite, and muscovite. Nb-Ta minerals in study area are columbite (Nb > Ta) in composition. Chemistry of muscovites shows post-magmatic in origin and they are closely related with columbite. Large columbite, in pegmatites occurred with quartz and feldspars, while microcrystalline columbite is associated with muscovite. The Nb contents in large columbite are relatively higher than those in microcrystalline ones. Two pegmatites, 4~15 m in width and 120 m, 250 m in extension respective1y, are developed. Five drilling cores with total 600 m in length are finally obtained and revealed no possible potential for economic rare metals of Na-Ta deposits.

• Korean Journal of Microbiology
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• v.40 no.3
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• pp.221-225
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• 2004

Novel cytochrome P450 hydroxylase (CYP) genes were isolated and characterized from P. autotrophica cosmid DNA library using an actinomycete CYP-specific PCR product as a screening probe. The cosmids containing four unique CYP genes (pESK601, 602, 603, 604, 605) were identified, and the four CYP genes were completely sequenced to be homologous to other known Actinomycetes CYP genes involved in various secondary metabolic pathways. Among all novel actinomycete CYP genes found in P. autotrophica, the CYP genes present in pESK601 were revealed to be highly homologous to the CYP genes involved in polyene-type amphotericin and nystatin antibiotic biosynthesis. The nucleotide sequences of the CYP flanking region in pESK601 also revealed the polyene-type biosynthetic genes, implying the presence of a cryptic polyene-type antifungal biosynthetic gene cluster in P. autotrophica.