• Journal of Chest Surgery
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• v.36 no.5
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• pp.329-334
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• 2003

Backgound: Cryoablation and radiofrequency ablation have been used to treat the atrial fibrillation. Some reports insisted that the microwave ablation Is a better method for a deep and extensive lesion. Material and Method: From December 2001 to July 2002, we peformed 8 microwave ablations in patients who needed mitral valve surgery (7 MVR, 1 MVR+AVR). There were 3 men and 5 women, and their mean age was 43.4$\pm$8.3 years and mean follow up period was 5.6$\pm$2.4 months respectively. The microwave was applied on endocardium or epicardium by Lynx (Afx, inc.) using a power of 45 watts for 25 seconds. We studied the left atrial dimension, the left atrial function and the sinus conversion with echocardiography and electro-cardiography at three times; 1) before the operation, 2) immediately after the operation, and 3) 6 months after the operation. Result: There was no complication and no mortality. The mean aortic clamping time was 104.6$\pm$25.0 minutes, and the mean total bypass time was 130.5$\pm$28.7 minutes. The rate of sinus conversion was 75%, A wave across the mitral valve was a mean of 77.0$\pm$24.8 cm/sec, and the AVE was a mean of 0.46$\pm$0.17 at 5.6 months postoperatively Conclusion: There was no difference in the early result of microwave ablation compared to other methods. The microwave ablation was an acceptable method due to its convenient application especially in beating heart.

• Sleep Medicine and Psychophysiology
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• v.14 no.1
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• pp.49-53
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• 2007

Mitochondrial myopathy is characterized by variable clinical manifestations from mild limb weakness to fatal respiratory failure and central nervous system sequela. But it is a rare event that sleep disordered breathing become a clue of diagnosis for mitochondrial myopathy. We report a case of a 21 year-old man who was diagnosed as mitochondrial myopathy during the investigation for the possible cause of chronic hypoventilation syndrome. Before being admitted to our hospital, he was suspected as having sleep apnea syndrome in another hospital. We re-evaluated the history, physical examination, laboratoy findings and polysomnography in detail. Severe hypoxemia was noted during REM sleep on nocturnal polysomnography and the diagnosis of mitochondrial myopathy was made by muscle biopsy in rectus abdominis muscle. We treated him with bilevel positive airway pressure therapy during sleep and it could reverse the hypoxemia during REM sleep. He could be discharged with improved condition and is being well with the use of this ventilatory assistance.

• Korean journal of applied entomology
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• v.21 no.4 s.53
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• pp.200-206
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• 1982

A computer simulation model was constructed to explore the phonology of the Striped Rice Borer, Chilo suppressalis (Walker), in Korea. The phenological system model based on the concept of distributed time delay was written in the computer program 'INSECT' and simulated with the estimated parameters of the effective day-degrees (DEL) and the order of time delay (K) for determining the validity of the system model. The accumulated emergence curves obtained from the phenological model were slightly different from the observed light trap data at the early and late stage of the moth emergence in 1978. The differences between observed and simulated $50\%$ emergence date were five to six days in the locations of Suweon and Chuncheon, while it was only two to three days in Iri, Daegu, Boseong, and Milyang. The phenological model should be further improved for simulation of field population changes by adding the information of the time delay process in each developmental stage, the age distribution of overwintered population, and the limiting factors of the borer mortality.

• Nuclear industry
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• v.37 no.9
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• pp.58-90
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• 2017

'공포의 값비싼 대가(The High Cost of Fear)'는 공개된 자료 중 동료 평가를 마친 최신의 자료와 간단한 계산 방법을 통해 한국의 탈원전 정책이 가져올 경제적, 환경적 영향을 분석한 보고서이다. 우리는 탈원전 정책이 다음과 같은 영향을 미칠 것으로 예측한다. ${\cdot}$천연가스 구매에만 최소 매년 100억 달러의 비용이 들 것이다. 이는 한국 평균임금인 연소득 29,125달러를 받는 일자리 343,000개에 해당하는 금액이다. ${\cdot}$비용의 대부분은 연료 수입에 사용될 것이며, 한국의 무역 수지가 악화될 것이다. ${\cdot}$한국의 부족한 재생에너지 자원을 고려할 때, 상당한 양의 화석 연료를 추가로 사용하게 될 것이다. ${\cdot}$LNG 발전소가 석탄 발전소를 대체하지 못하고 원자력발전소를 대체하면서 대기 오염으로 인한 조기 사망자 수가 증가할 것이다. ${\cdot}$한국의 전도유망한 원전 수출 산업이 아예 붕괴되거나 큰 타격을 입을 것이다. ${\cdot}$평균적 미국 자동차의 연간 주행거리를 기준으로 150만대에서 270만대의 미국 자동차가 배출하는 배기가스의 양만큼 연간 탄소 배출이 증가할 것이고, 한국은 파리기후협정에서 약속한 탄소 배출 감축 목표를 달성할 수 없게 된다. 본 보고서는 현재 계획된 탈원전 정책의 역사적 사회적 배경을 분석하여 다음과 같은 결론을 도출하였다. ${\cdot}$'그린피스(Greenpeace)', '지구의 친구들(Friends for the Earth)' 등 막대한 자금 지원을 받는 해외 환경단체들은 탈원전 거짓 정보의 근원이며, 이들은 저렴하고 풍부한 에너지라는 개념을 반대한다. ${\cdot}$후쿠시마 원전 사고와 그 여파의 주된 원인은 일본 원자력산업계의 오만과 원자력에 대한 과장된 집단 공포이다. ${\cdot}$반핵 진영의 논리에는 산업계와 정부에 대한 불신과 원자력, 방사선에 대한 몰이해가 반영되어 있다. ${\cdot}$반핵 진영은 후쿠시마 사고를 2014년 한수원 납품 비리 사태의 심각성을 과장하는 데 사용하고 있다. 2014년의 비리 사태는 한국 원자력 규제기관의 독립성을 증명했으며, 2016년의 경주 지진은 2011년 후쿠시마에서 쓰나미와 노심 용융을 초래한 동일본 대지진의 1/350,000의 크기밖에 되지 않는다. 본 보고서는 한국과 타국가의 반핵 운동이 주는 교훈을 다음과 같이 정리하였다. ${\cdot}$어떠한 국가도 에너지 자원 최빈국인 프랑스나 한국 같은 국가조차도 탈원전 '전쟁'에서 자유롭지 않으며, 이는 전 세계적으로 원자력산업이 쇠퇴하는 원인이다. ${\cdot}$원자력산업계, 정부, IAEA 등은 한국과 세계 여러 국가에서- 문화적, 제도적, 재정적 원인으로 원자력산업의 보호와 확대라는 목표를 달성할 수 없다. ${\cdot}$원자력산업을 구하기 위해서는 새로운 비전과 새로운 제도, 그리고 새로운 리더십이 필요하다. ${\cdot}$원자력의 근원적이고 혁신적인 비전 원자력 인본주의(atomic humanism)에 대한 재조명이 필요하다. ${\cdot}$원자력을 지키고 대중과 소통하기 위해 과학 연구단체, 대학교, 사단법인, NGO 등의 새로운 기관들을 후원해야 한다. ${\cdot}$공포를 조장하는 반원전 세력에 맞서 공포를 극복해야 하고, 대중의 공포를 극복해왔던 다른 기술들의 사례에서 교훈을 얻어야 한다.

• Tuberculosis and Respiratory Diseases
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• v.42 no.5
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• pp.737-743
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• 1995

Background: Pneumonia is a frequent complication in patients undergoing mechanical ventilation, Quantitative culture of protected specimen brush(PSB) have shown satisfactory diagnostic accuracy for the diagnosis of ventilator-associated pneumonia. However PSB method is invasive, expensive, and require a bronchoscopic procedure. But endotracheal aspiration(EA) is simple and less expensive. The purpose of our study was to investigate the diagnosic value of EA quantitative cultures. Method: We studied 15 cases of ventilator-associated pneumonia(for >72h of mechanical ventilation) patients. Patients were divided into two diagnostic categories. Group I was the patients who were suspicious of clinical pneumonia, Group II was the patients for control. The obtained samples by EA and PSB were homogenized for quantitative culture with a calibrated loop method in all patients. Result: Using $10^3cfu/ml$, $10^5cfu/ml$ as threshold in quantitative culture of PSB, EA respectively, we found that EA quantitative cultures represented a relatively sentive(70%) and relatively specific (60%) method to diagnose the ventilator-associated pneumonia. Conclusion: Although EA quantitative cultures are less specific than PSB for diagnosing ventilator-associated pneumonia. EA quantitative cultures correlated with PSB quantitative culture in patients with clinical pneumonia and may be used to treat these patients when bronchoscopic procedures are not available.

• Journal of the Korean Society of Radiology
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• v.13 no.6
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• pp.873-878
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• 2019

Cerebrovascular disease is one of the three major causes of death in Korea. Since these diseases are associated with atherosclerosis, the diagnosis of atherosclerotic factors should be presented. In this study, we evaluated the relationship between brachial-ankle arterial pulse wave velocity, cerebral artery vascular stenosis, blood pressure, obesity, and abdominal obesity by age group. The significance of cerebral artery stenosis and age group. The risk factors of atherosclerosis, such as blood pressure, obesity, and abdominal obesity, were significant in all age groups. When the pulse wave velocity of the brachial-ankle artery was increased, the cerebral artery stenosis was distributed in 57.3% of the total test subjects. If the arterial stiffness is suspected during the measurement of the pulse wave velocity of the brachial ankle artery, We recommend suspected vascular stenosis and perform a cerebral artery angiography. It is suggested that the data will be used as a baseline data for similar studies after evaluating the significance of blood pressure, obesity, and abdominal obesity as risk factors of atherosclerosis.

• Proceedings of the Korea Water Resources Association Conference
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• 2015.05a
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• pp.558-558
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• 2015

하천 시설물은 홍수시 혹은 비상시 운영할 수 있는 경보시스템이나 관리지침 등의 마련이 필수적임에도 불구하고, 현재까지 가동보 시설물에 대한 비상시 운영 메뉴얼 및 경보시스템이 구축되지 못한 실정이다. 4대강 살리기 사업이나 하천정비사업과 같은 대표적인 하천관련 사업에서 단순한 하천 이 치수 목적뿐만 아니라 소수력 발전, 친수공간조성 등의 다목적 활용을 위하여 가동보 설치 사업이 다수 수행되었으며, 현재 국내 하천에 약 1,200여개의 가동보가 설치 운영되고 있다. 이와 같이 다목적 활용을 위하여 가동보의 수요가 급증하는데 반해, 각 설치 현장 상황에 적합한 가동보 운영지침이나 비상경보시스템이 구축되지 못한 실정이며, 적절한 지침 없이 관행적인 가동보 방류로 인한 물놀이 안전사고나 인명피해가 속출하고 있는 실정이다. 2012년 11월에는 하천 제수변 공사를 위해 전주천에 설치한 가동보를 임시적으로 방류하였는데, 하류측의 안전을 확인하지 않고 관행적으로 가동보를 방류하였고, 경보시스템의 부재로 인하여 가동보 하류측 징검다리를 건너는 유치원생들이 급류에 휩쓸리는 사고가 발생하였고, 최근 2014년 5월에는 수원시에 위치한 원천저수지 여수로 둑에 설치된 가로 34m 높이 1.6m 크기의 가동보가 공기압축기의 오작동으로 인하여 보 높이가 낮아지면서 약 30분 원천저수지 하류의 원천리천에 갑자기 무리 불어나 산책로가 침수되고 인근에 산책하던 주민들이 휩쓸려 떠내려가는 사고가 발생하였다. 해외에서도 가동보 운영 미숙으로 인하여 인명사고가 발생하는데, 2008년 11월 호주에서는 하류측 상황 점검이나 경고 방송 없이 가동보를 도복시켜 4살 여아가 급류에 사망하는 사고가 발생하였다. 국외의 경우에는, 상류측 홍수 수위나 하류측 역류 수위를 조절하기 위하여 가동보의 높이를 제어하는 시스템을 구비하고 있지만 이러한 시스템 역시 단순한 수위조절 기능으로서 가동보의 방류량을 제어하지 못하는 실정이다. 가동보를 운영하기 위한 조작시스템은 국내의 경우, 조작실의 조작판넬을 이용하여 가동보의 기립/도복 조작이나 원격 조작 기능과 같은 단순기능만을 구비하고 있어 가동보 방류시 하류측의 범람 피해를 야기하고 있다. 본 연구에서는 가동보 방류에 의한 하류측 범람 피해를 최소화하기 위하여 (1) 가동보 도복에 의한 방류량 산정 알고리즘을 개발하고, (2) 방류량에 따른 하류측 수위상승 범위 예측 기법을 개발하고, (3) 가동보 도복 속도를 제어하는 방류량 제어시스템을 개발하고, (4) 가동보 방류에 의한 비상경보시스템을 개발하였다.

• Journal of The Korean Society of Clinical Toxicology
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• v.19 no.2
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• pp.72-82
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• 2021

Purpose: A high anion gap (AG) is known to be a significant risk factor for serious acid-base imbalances and death in acute poisoning cases. The strong ion difference (SID), or strong ion gap (SIG), has recently been used to predict in-hospital mortality or acute kidney injury (AKI) in patients with systemic inflammatory response syndrome. This study presents a comprehensive acid-base analysis in order to identify the predictive value of the SIG for disease severity in severe poisoning. Methods: A cross-sectional observational study was conducted on acute poisoning patients treated in the emergency intensive care unit (ICU) between December 2015 and November 2020. Initial serum electrolytes, base deficit (BD), AG, SIG, and laboratory parameters were concurrently measured upon hospital arrival and were subsequently used along with Stewart's approach to acid-base analysis to predict AKI development and in-hospital death. The area under the receiver operating characteristic curve (AUC) and logistic regression analysis were used as statistical tests. Results: Overall, 343 patients who were treated in the intensive care unit were enrolled. The initial levels of lactate, AG, and BD were significantly higher in the AKI group (n=62). Both effective SID [SIDe] (20.3 vs. 26.4 mEq/L, p<0.001) and SIG (20.2 vs. 16.5 mEq/L, p<0.001) were significantly higher in the AKI group; however, the AUC of serum SIDe was 0.842 (95% confidence interval [CI]=0.799-0.879). Serum SIDe had a higher predictive capacity for AKI than initial creatinine (AUC=0.796, 95% CI=0.749-0.837), BD (AUC=0.761, 95% CI=0.712-0.805), and AG (AUC=0.660, 95% CI=0.607-0.711). Multivariate logistic regression analyses revealed that diabetes, lactic acidosis, high SIG, and low SIDe were significant risk factors for in-hospital mortality. Conclusion: Initial SIDe and SIG were identified as useful predictors of AKI and in-hospital mortality in intoxicated patients who were critically ill. Further research is necessary to evaluate the physiological nature of the toxicant or unmeasured anions in such patients.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.19 no.11
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• pp.550-560
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• 2018

Many countries have provided support for research and development and implemented policies for Advanced Driver Assistance Systems (ADAS) for enhancing the safety of vehicles. With such efforts, the toll of casualties due to traffic accidents has decreased gradually. Korea has exhibited the lowest toll of casualties due to traffic accidents and is ranked 32nd in mortality among the 35 OECD members. Traffic accidents typically fall into three categories depending on the cause of the accident: vehicle to vehicle (V2V), vehicle to pedestrian (V2P), and vehicle independent. Most accidents are caused by drivers' mistakes in recognition, judgment, or operation. ADAS has been proposed to prevent and reduce accidents from such human errors. Moreover, the global automobile industry has recently been developing various safety measures, but on-road tests are still limited and contain various risks. Therefore, this study investigated the international standards for evaluation tests with regard to the assessment techniques in braking capability to cope with the limitations of on-road tests. A theoretical formula for braking force and a control algorithm are proposed, which were validated by comparing the results with those from an on-road test. These results verified the braking force depending on the functions of ADAS. The risks of on-road tests can be reduced because the proposed theoretical formula allows a prediction of the tendencies.

• Korean Chemical Engineering Research
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• v.57 no.4
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• pp.475-483
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• 2019

Special chemical warfare agents are lethal gases that attack the human respiratory system. One of such gases are blood agents that react with the irons present in the electron transfer system of the human body. This reaction stops internal respiration and eventually causes death. The molecular sizes of these agents are smaller than the pores of an activated carbon, making chemical adsorption the only alternative method for removing them. In this study, we carried out a Computational Fluid Dynamics simulation by passing a blood agent: cyanogen chloride gas through an SG-1 gas mask canister developed by SG Safety Corporation. The adsorption bed consisted of a Silver-Zinc-Molybdenum-Triethylenediamine activated carbon impregnated with copper, silver, zinc and molybdenum ions. The kinetic analysis of the chemical adsorption was performed in accordance with the test procedure for the gas mask canister and was validated by the kinetic data obtained from experimental results. We predicted the dynamic behaviors of the main variables such as the pressure drop inside the canister and the amount of gas adsorbed by chemisorption. By using a granular packed bed instead of the Ergun equation that is used to model porous materials in Computational Fluid Dynamics, applicable results of the activated carbon were obtained. Dynamic simulations and flow analyses of the chemical adsorption with varying gas flow rates were also executed.