• Title/Summary/Keyword: 사람의 개입

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Blood Biomarkers for Alzheimer's Dementia Diagnosis (알츠하이머성 치매에서 혈액 진단을 위한 바이오마커)

  • Chang-Eun, Park
    • Korean Journal of Clinical Laboratory Science
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    • v.54 no.4
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    • pp.249-255
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    • 2022
  • Alzheimer's disease (AD) represents a major public health concern and has been identified as a research priority. Clinical research evidence supports that the core cerebrospinal fluid (CSF) biomarkers for AD, including amyloid-β (Aβ42), total tau (T-tau), and phosphorylated tau (P-tau), reflect key elements of AD pathophysiology. Nevertheless, advances in the clinical identification of new indicators will be critical not only for the discovery of sensitive, specific, and reliable biomarkers of preclinical AD pathology, but also for the development of tests that facilitate the early detection and differential diagnosis of dementia and disease progression monitoring. The early detection of AD in its presymptomatic stages would represent a great opportunity for earlier therapeutic intervention. The chance of successful treatment would be increased since interventions would be performed before extensive synaptic damage and neuronal loss would have occurred. In this study, the importance of developing an early diagnostic method using cognitive decline biomarkers that can discriminate between normal, mild cognitive impairment (MCI), and AD preclinical stages has been emphasized.

The Impact of Childhood Abuse Experience on Adults' Disconnection/Rejection Schemas: A Comparison of Moderating Effects of Inhibition and Reinterpretation (아동기 학대 경험이 성인의 단절/거절도식에 미치는 영향 :억제와 재해석의 조절효과 비교)

  • HANNAH PARK
    • The Journal of the Convergence on Culture Technology
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    • v.10 no.3
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    • pp.165-172
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    • 2024
  • This study illuminates the relationship between childhood abuse experiences and early maladaptive schemas, and compares the moderating effects of expressive suppression and cognitive reappraisal within this relationship. Conducting a self-report survey among 220 graduate students in Daejeon and Chungcheong regions, data from 210 participants were analyzed. The results notably revealed that the interaction effect of suppression, but not cognitive reappraisal, significantly moderates the relationship between childhood abuse experiences and disconnection/rejection schemas. Specifically, high levels of expressive suppression were associated with a decrease in the negative impact of childhood abuse on disconnection/rejection schemas, whereas low levels of suppression increased this negative impact. This suggests that for individuals with long-standing early maladaptive schemas, which have solidified over time akin to personality traits, cognitive reappraisal strategies may be less effective in inducing change. Conversely, expressive suppression strategies may more effectively reduce the intensity of disconnection/rejection schemas, among other early maladaptive schemas. These findings provide important implications for understanding the long-term effects of childhood abuse and developing intervention strategies to mitigate its resultant maladaptive schemas. Based on the outcomes of this study, suggestions for future research are discussed, along with the potential applicability and limitations of suppression and reappraisal strategies in psychological interventions.

A Study on the Place Identity of Shin-Cheorwon with the Intrinsic Everydayness -By Using Photovoice Methodology- (일상성이 내재된 신철원 장소정체성 연구 - 포토보이스 방법론을 활용하여 -)

  • Suh, Joon Won;Chung, Da Ae;Park, Yunju
    • Journal of the Korean Institute of Landscape Architecture
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    • v.50 no.1
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    • pp.53-67
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    • 2022
  • This study started from recognizing the need to study place identity from the perspective of residents experiencing the place in daily life. The subject area of the study, Shin-Cheorwon, Galmal-eup, Cheorwon-gun, Gangwon-do area, had a low population until the division of Korea in 1945. Since then, the residents have created the milieu under Shin-Cheorwon's regional historic and cultural context. Thus, the study on this area can show the formation of the interrelationship of the region and residents. The purpose of this study is to understand the meaning and identity of the everyday places of Shin-Cheorwon. Photovoice was chosen as the method for successful Participatory Research; Participant's active intervention stage, 'Documentation (4th step)', Narration (5th step), researcher's analysis stage 'Ideation (6th step)' were specifically used. As a result, the following characteristic of the places chosen by participants could be found: the meaning and relationship with the residents, similarities, and differences in people shown based on their age, length of residence, etc. Through this, participants recollected the past places, found the meaning of the place of the present, and deduced the placeness that Shin-Cheorwon should have in the future. The study identified the place identity that holds the perspective of the residents in their daily life and provides implications on the follow-up studies of place identity. In addition, it is expected that it will apply to urban planning and spatial design in further studies of how residents perceive the space formed by urban development using photovoice methodology.

Some Comments on the Preparation of the CSK Standard Chemical Solutions (CSK Standard Chemical Solution 과 그에 대한 몇가지 의견)

  • Won, Chong Hun
    • 한국해양학회지
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    • v.4 no.2
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    • pp.83-86
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    • 1969
  • 해양관측의 세계적인 공통성으로 해서 염분검정법이 이미 오래 전부터 통일화 되었지만 근래에 와서는 용존산소량 정량법도 국제적인 Intercalibration을 하는 등규격화에의 기운이 나고 있다. 다시 Kuroshio 합동조사에서는 영양염의 정량에 있어 공통된 표준용액을 사용하므로써 조작상의 편리와 측정치의 신뢰성을 더욱 향상시키자는 의도에서 일본이 국제적인 영양염 표준용액의 조제 및 배포에 관한 안을 내어 1965년 Manila 회의를 거쳐 일본 상모중앙화학연구소의 관원씨가 이를 맡아 1966년부터 시작하여 1967년까지에 요오드산칼리움, 아질산염, 인산염, 규산염의 표준용액을 만들어 1968년 봄부터 시험적으로 일본국내와 동남아 수개국에 나누어 사용해 왔던 것이다. 다시 1968년 9월의 SCOR 의 영양염에 관한 Working Group 회의에서 CSK Std. Solution을 사용하여 세계각국에서 현재 사용하고 있는 영양염 분석방법의 Intercalibration을 하자는 회의가 있었고, 이것을 권고사항으로 SCOR에 보고하여 1968년 11월에 ICES가 승인하므로써 Intercalibration에 관한 원칙이 정해졌다. 동시에 Finland의 Koroleff씨와 Palmork씨가 organizer로 정해졌던 것이다. 이 보다 약간 앞서 본인이 상모중연에 가 있을 때 Std. Solution으로서 아질산염용액 만으로 각종무기질소화합물의 표준용액으로 대용한다는 것은 비합리적이므로 질산염과 암모늄염의 표준용액이 있어야 한다고 주장하여 우선 질산염용액을 추가로 만들기로 하여 1968년 11월부터 표준물질의 정제부터 시작 되었다. 1969년 1월에 Intercalibration 에 관한 구체적인 회의를 위해 Scripps 해양연구소에 관원, Wooster Rakestraw, Cieskes씨등이 모여 우선 일본상모중연에서 만들고 있는 인산염, 질산염, 아질산염, 규산염의 CSK 표준용액을 표준시료로하여 SCOR 과 ICES의 해양화학분과에서 선정한 세계 100개처에 나누어 현재 각자가 사용하고 있는 방법의 정밀도와 정확도를 check하는 소위 International intercalibration을 1969년 9월부터 시작하기로 확정을 보았고, 동시에 구체적인 지시가 있었던 것이다. 이시료를 받는 사람에게는 다만 그것의 농도범위만 알려주고 정확한 농도는 Koreleff와 관원씨만이 알고 있기로 하여 측정에 분석자의 주관이 개입되지 못하도록 했고, 분석치는 SCOR가 모아 해석하되 번호제로 하여 어떤 나라의 누구가 했다는 것은 밝히지 않기로 되어 있다. 이같은 내력으로 CSK Std. Solution이 국제적인 Intercalibration용의 표준시료로서 시험적으로 사용되기 까지는 되었으나, CSK Std. Solution 그자체에 관해서는 아직도 해결해야 할 점, 개량을 요하는 점이 많다. 이하에서는 주로 개량을 요하는 점에 관해 몇가지 언급하고자 한다.

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Discovery and Execution Techniques of Semantic Web Services for Dynamic Web Services Composition (동적 웹 서비스 조합을 위한 시멘틱 웹 서비스 발견 및 실행 기법)

  • Lee Yong-ju
    • The KIPS Transactions:PartD
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    • v.12D no.6 s.102
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    • pp.889-898
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    • 2005
  • Recently, one of the most challenging problems is to compose web services dynamically, that is, on demand. A number of researchers have been considerably interested in the dynamic web services composition. However, while most of them focused on the semi-automatic web services composition with a human controller, very little attention was devoted to the full automation of this process. This paper primarily focuses on the automatic web services composition techniques. The main idea is to implement an automatic web services composition system using web ontologies to realize the semantic web and workflow technologies to play a major role in E-businesses. In this paper, we propose a matching algorithm for web service discovery and present an approach based on the use of ontologies to facilitate the interoperability of web services. Finally, we describe a workflow execution plan to support the automatic web services composition, and an experimental study that shows the high performance of our system.

A Study on Eco-systemic Factors that affect the job satisfaction of the care givers who involved in long-term care service center (요양보호사의 직무만족에 영향을 미치는 생태체계적 요인에 관한 연구)

  • Lee, Eun Hee;Jung, Bo-Kyoung
    • Journal of Digital Convergence
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    • v.10 no.10
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    • pp.383-388
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    • 2012
  • The purpose of this study is to examine the eco-systemic factors that affect the care givers' job satisfaction, and to attain the real data that is useful for increasing the care givers' job satisfaction. The subjects were 195 care givers who involved in long-term care service center in D city. Collected date were analyzed through frequency, percentage, correlation and hierarchical regression analysis. The results are as follow. The factors that affect the care givers' job satisfaction are the age of care givers, the levels of self-esteem, the respect from client, and the levels of support received from friend. The implication of our findings is that for the puporse or increasing the care givers' job satisfaction, the education programs for the care givers and client are necessary.

Effects of Stigma on Help-Seeking Intentions for Suicidal Ideation: Focused on Korean Soldiers (낙인이 자살생각에 대한 도움요청의도에 미치는 영향: 한국 군 병사를 대상으로)

  • Kim, Ji-In;Kwon, Ho-In
    • The Journal of the Korea Contents Association
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    • v.17 no.11
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    • pp.29-38
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    • 2017
  • The purpose of this study is to find out factors affecting intentions to seek help for suicidal ideation in Korean Army and to provide a basis for approaches to facilitate formal or informal help seeking for suicidal ideation. A total of 471 Korean soldiers participated in the current study. First, the question of whether suicidal ideation have a significant influence on general help seeking, and whether public stigma and self stigma mediate the relationship between suicidal ideation and general help seeking were examined. According to the results, public stigma and self stigma partially mediated the relationship between suicidal ideation and general help seeking, indicating that suicidal ideation not only has an indirect effect on general help seeking through public stigma and self stigma, but also has a direct influence on general help seeking.

Biofeedback Treatment for Tension-Type Headache and Migraine (긴장성두통과 편두통의 바이오피드백 치료)

  • Park, Joo-Eon;Lee, Kye-Seong;Shin, Sang-Eun
    • Korean Journal of Psychosomatic Medicine
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    • v.14 no.1
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    • pp.25-32
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    • 2006
  • Objectives : Headache is a clinical symptom that more than 90% of all individuals experience during their life time. This article provides a current concept of tension-type and migraine headaches and summarizes the effects of biofeedback treatment and/or relaxation techniques. Methods : The following terms were used for Pubmed/Medline search : biofeedback, relaxation, physiological, behavioral, nonpharmacological, headache, tension-type headache, and migraine. A review of references from relevant literature was also conducted to collect reports not identified in the Pubmed/Medline search. Interviews with experts on biofeedback were also included in this review. Results : Headache is a psychophysiological symptom that can be treated by some behavioral interventions including biofeedback and relaxation. Literatures on biofeedback and/or relaxation have consistently reported significant therapeutic effects on headaches. Important factors that we have to consider, when we apply to headache patients with biofeedback and relaxation techniques, were also presented. Conclusion : The available evidence suggests that biofeedback and relaxation techniques are effective treatments for the patients with headaches and can be provided to the patients as monotherapy or combination therapy with medication.

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Development and Analysis of Effect for Problem Solving Model of Student-based (학생중심의 문제해결 모형 개발 및 효과 분석)

  • Jung, Chan Sik;Roh, Eun Hwan
    • Education of Primary School Mathematics
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    • v.17 no.1
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    • pp.57-75
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    • 2014
  • Problem Solving has been emphasized for recent decades, and many research case studies have been used to improve students' Problem Solving abilities. However, the gap of students' abilities can be easily shown after enrollment into school in spite of scholar's attempt to reduce students' level of differentiation. Besides, it is clear that teachers have been too readily assisting students' and not allowing them to acquire the process of Problem Solving, and this may be due to impatience. Therefore, students seem to show signs of the dependent tendency towards teachers and other materials. This tendency easily allows students' to depend on teaching resources without attempting any developmental mechanism of Problem Solving. The presupposition of this study is that every student must solve a problem without any assistance, and also this study is to provide new cognitive strategies for both teachers and students who want to solve their problems by themselves through the process of visible Problem Solving. After applying the student-based problem-solving model by this study, it was found to be effective. Therefore this will lead to the improvement of the Problem Solving and knowledge acquisition of students.

An Group-based Security Protocol for Machine Type Communications in LTE-Advanced (LTE-Advanced에서의 Machine Type Communications을 위한 그룹 기반 보안 프로토콜)

  • Choi, Dae-Sung;Choi, Hyoung-Kee
    • Journal of the Korea Institute of Information Security & Cryptology
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    • v.23 no.5
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    • pp.885-896
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    • 2013
  • MTC(Machine Type Communications), providing a variety of services anytime and anywhere by connecting the cellular network to the machine and things without human intervention, is being considered as a major challenge of the next-generation communications. Currently, When a massive MTC devices simultaneously connect to the network, each MTC device needs an independent access authentication process. Because of this process, authentication signaling congestion and overload problems will cause in LTE-Advanced. In this paper, we propose a group-based authentication protocol and a key management protocol. For managing the MTC devices as group units, the proposed protocol elects a group leader and authentications only once with the core network. After the authentication is completed, a group leader manages the rest members and MME(Mobility Management Entity) by constructing a binary tree. Finally, the propose protocol analysis show that the proposed protocol not only can reduces the authentication signaling which generated in between the MTC devices and the core network but also can manages the MTC devices, efficiently.