• Korean Journal of Food Science and Technology
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• v.31 no.3
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• pp.823-830
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• 1999

The suppressing effects of crude extracts of three Korean teas, persimmon leaf tea extract (PLTE), green tea extract (GTE) and oolong tea extract (OTE), were studied on the induction of sister chromatid exchange (SCE) in cultured Chinese hamster ovary cells. When cells were treated with tea extract after mitomycin C (MMC) treatment, the frequency of MMC-induced SCEs were decreased at the high concentration $(1000\;{\mu}g/mL)$ of PLTE in the presence of S9 mix and at low concentrations $(20{\sim}80\;{\mu}g/mL)$ of PLTE in the absence of S9 mix, Whereas GTE and OTE showed suppressing effects on the MMC-induced SCEs at low concentrations $(10{\sim}20\;{\mu}g/mL)$ for OTE and $160\;{\mu}g/mL$ for GTE only in the presence of S9 mix. MMC-induced SCEs were decreased by post-treatment with each tea extracts with S9 mix in the G1 phase of the cell cycle. These results suggest that PLTE, GTE and OTE could have bio antimutagenic activities, and also suggest that PLTE might have unknown antimutagenic components which would be responsible for the inhibitory effect against direct acting mutagenicity.

• The Journal of the Acoustical Society of Korea
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• v.27 no.6
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• pp.303-308
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• 2008

The purpose of the present study is to investigate that word frequency has significant influence on noun definitions in Korean. The experimental group was 80 students from Elementary school, Middle school, High school and University. They rated familiarity and wrote definitions for nouns. Noun definitions were analyzed with semantic categories such as "use/purpose," "description," "association/relation," "partial explanation," "explanation," "error," "partial explanation-attribute," "partial explanation-specific class," "partial explanation-nonspecific class," "explanation-specific class," "explanation-nonspecific class." As a result, they showed familiarity for high-frequency nouns. "EXPL" categories that use class terms or critical attributes were used more frequently in definitions of high-frequency nouns compared with low-frequency nouns. They increased with age and errors decreased with age. Word frequency had a significant influence on noun definitions.

• Korean Journal of Cognitive Science
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• v.20 no.3
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• pp.335-355
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• 2009

We examined risk judgment and the accuracy of inference based on two kinds of probabilities in a Bayesian inference task: the death probability from a disease (base rates) and the probability of having a disease with positive results in the screening test (posterior probabilities). Risk information were presented in either a probability or a frequency format. In Study 1, we found a numerical format effect for both base rate and posterior probability. Participants rated information as riskier and inferred more accurately in the frequency condition than in the probability condition for both base rate and posterior probability. However, there was no frequency range effect, which suggested that the ranges of frequency format did not influence risk ratings. In order to find out how the analytic thought system influences risk ratings, we compared the ratings of a computation condition and those of a no-computation condition and still found the numerical format effect in computation condition. In Study 2, we examined the numerical format effect and frequency range effect in a high and a low probability condition and found the numerical format effect at each probability level. This result suggests that people feel riskier in the frequency format than in the probability format regardless of the base rates and the posterior probability. We also found a frequency range effect only for the low base rate condition. Our results were discussed in terms of the dual process theories.

• Korean Journal of Cognitive Science
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• v.20 no.3
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• pp.309-333
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• 2009

Two experiments were conducted to examine the role of Kulja and morpheme in processing two-syllable Sino-Korean words. In Experiment 1, the effects of morphemic frequency were not significant at the initial and final positions of a word while Kulja frequency and Kulja-morpheme correspondence at both positions in a word had a significant impact on the processing of nonwords. Lexical decision times were longer for nonwords with high frequency Kulja and for nonwords with ambiguous Kulja-morpheme correspondence whose Kulja can go with many different morphemes. In Experiment 2 Kulja-morpheme correspondence was examined for words as well as nonwords. Lexical decisions were slower for stimuli with ambiguous Kulja-morpheme correspondence. The effect was more stable for nonwords, which replicated the result of Experiment 1. In sum, the results of this study suggest that words with ambiguous Kulja-morpheme correspondence activate many different morphemes and competition among these morphemic candidates slows down the lexical selection process. Kulja frequency, Kulja neighborhood, morphemic frequency, morphological neighborhood, and Kulja-morpheme correspondence in Korean word recognition were also discussed.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.17 no.1
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• pp.54-61
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• 2016

Because a word is the basic unit of language processing, studies of the word recognition processing and the variables that contribute to word recognition processing are very important. Word frequency and word length are recognized as important factors on word recognition. This study examined the effects of those two variables on the Korean word recognition processing. In Experiment 1, two types of Hangul words, pure Hangul words and Hangul words with Hanja counterparts, were used to explore the frequency effects. A frequency effect was not observed for Hangul words with Hanja counterparts. In Experiment 2, the word length was manipulated to determine if the word length effect appears in Hangul words. Contrary to the expectation, one syllable words were processed more slowly than two syllable words. The possible explanations for these results and future research directions are discussed.

• Journal of the Korean Society of Food Science and Nutrition
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• v.25 no.2
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• pp.232-239
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• 1996

돌연변이 유발 물질인 mitomycin C(MMC)를 처리하여 배양한 Chinese hamster ovary(CHO) cell에 대한 감잎차 추출액의 항돌연변이 효과를 자매 염색 분체 교환(sister chromatid exchange, SCE) 시험법을 사용하여 측정하여 보았다. 감잎차 추출액 자체는 CHO 세포의 SCE 빈도수를 변화시키지 않았으며, 세포의 분열 주기중 S phase에 S9 mixture 없이 감잎차 추출액이 처리되었을 경우 MMC로 유도된 SCE 빈도수를 감소시키지 않았다. 그러나 S9 mixture 존재하에 $G_{1}$ phase에서 MMC 처리 후 감잎차를 처리하는 후처리 방식으로 감잎차 추출액을 처리하였을 때, 저농도($\leq$40$\mu\textrm{g}$/ml)에서 MMC로 인해 유발된 SCE 빈도수가 낮아지는 것을 볼 수 있었다. 이에 비해 고농도(>40$\mu\textrm{g}$/ml)에서는 SCE 빈도수의 감소 효과가 없었다. 본 연구결과, MMC 처리된 CHO 세포에 대한 감잎차 추출액의 항돌연변이 효과를 볼 수 있었고, 이 효과는 S9 mixture 존재하에서 저농도의 감잎차 추출액이 $G_{1}$ phase에 처리되었을 때 나타났다. 감잎차 추출액의 이러한 항돌연변이의 효과의 기전은 감잎차 추출액의 대사산물이 MMC 처리된 CHO 세포에 대한 DNA-excision repair activity를 촉진시키기 때문인 것으로 생각된다.

• Annual Conference on Human and Language Technology
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• 2009.10a
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• pp.255-257
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• 2009

본 논문은 한국어의 통사적 중의성이 언어정보처리에 어떠한 영향을 미치는지 알아보기 위하여 어휘판단과제(lexical decision task)를 실시하였다. 명사의 의미와 동사의 의미로 중의적인 어절을 사용하여 각각의 빈도가 영향을 미치는지를 살펴보고자 하였다. 개별 품사 정보가 모두 영향을 미친다면 각각의 빈도가 영향을 미치게 되고 누적빈도 효과가 발생하여 개별 품사의 빈도와 동일한 비교조건에서의 반응시간보다 빠를 것이다. 실험 결과, 중의어절에서의 반응시간이 가장 빠르게 발생하였고 이를 통해 하나의 중의어절이 의미하는 개별적인 품사 의미가 모두 언어정보처리에 영향을 미친다는 것을 의미한다.

• Phonetics and Speech Sciences
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• v.11 no.2
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• pp.45-56
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• 2019

This study investigated the interaction between phonological phrase boundary and word frequency variable in Korean speech processing. A word monitoring task was performed to examine the interference caused by the frequency effect of target word depending on whether a phonological phrase is formed within the target word. Frequency of target word (high vs low) and phonological phrase boundary (within target word vs between target words) were applied as between and within subject condition respectively. Our results showed the significant main effect of the phonological phrase boundary and the significant interaction. In the post-hoc analysis, the high-frequency target words were detected significantly faster than the low-frequency target words only in the within phonological phrase boundary condition. Frequency effect in the between phonological phrase boundary condition did not appear. The results indicated that the phonological phrase boundary and word frequency variable played an important role in Korean speech processing. In particular, we discussed the possibility of processing the word frequency at the very early sensory information processing stage based on the interaction of two experimental factors.

• Journal of the Korean Society of Physical Medicine
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• v.3 no.4
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• pp.301-307
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• 2008

목적 : 노년층의 대부분이 가지고 있는 골관절염이라고도 알려진 퇴행성 관절 질환은 척추에 영향을 끼친다. 그리고 이 질환은 통증과 일상생활에서의 활동 제한을 초래한다. 본 연구는 퇴행성 관절질환 환자의 물리치료 빈도에 따른 효과를 검증하는 데 있다. 방법 : 퇴행성 관절 질환을 가진 30명의 환자가 이 연구에 참여하였고 이들에 취해진 물리치료의 빈도에 따른 효과를 평가하여 그 결과를 물리치료 임상 지침서와 비교분석하였다. 본 연구에 참여한 환자들은 시각적 사상척도(Visual Analog Scale, VAS), 멕길 통증 설문지, 일반적인 설문지에 응했으며 물리치료 전과 후를 물리치료 빈도에 중점을 두어 평가받았다. 결과 : 본 연구에 참여한 환자들은 제시된 치료 빈도와 평가에 근거하여 볼 때 놀랄만한 호전을 보였다. 치료 초기와 물리치료를 시작하기 전의 평가 자료를 비교하여 보았을 때 설문지로 평가된 점수에서 큰 향상을 보였다. 결론 : 본 연구는 물리치료가 퇴행성 관절 질환 환자들에게 효과가 있음을 보여주었다. 또한 물리치료 임상지침서는 따라야 할 좋은 자료가 될 수 있지만 물리치료 처방에는 정해진 기준은 없다는 것을 보여주었다.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.14 no.3
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• pp.1207-1212
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• 2013

The purpose of this study was to examine the effect of transcutaneous electrical nerve stimulation (TENS) according to frequency and intensity on postural sway distance and velocity. TENS was applied to posterior aspect of the dominant leg with postural sway during one leg stance. Twenty-four healthy participants were measured while standing on a force platform with 5 different stimulation dosages of no TENS, high frequency and high intensity, high frequency and low intensity, low frequency and high intensity, low frequency and low intensity applied in 30 seconds. The five different dosages were performed with vision in random order. The results indicated that TENS dosage in the high frequency and low intensity had a significant decrease in postural sway(p<.05). From these results, we concluded that TENS delivered a high frequency and low intensity enhanced the postural sway in healthy adults. We expect that the postural sway of patients with decreased balance will reduce by application of TENS.