• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2017.05a
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• pp.171-174
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• 2017

One of the treatments and preventions of strokes such as ischemic stroke is to increase cerebral blood flow. This aims to minimize the size of the stroke by increasing the quantity of blood to the cerebral region circuitously. Several ways to increase cerebral blood flow are a therapy though drugs and through surgery. However these invasive method giving a burden to the patient, the problem of inducing a number of complications were noted. In this thesis, we propose a non-invasive cerebral blood flow augmentation device to compensate for the disadvantages of these invasive treatments. To compensate for the shortcomings of the existing cerebral blood flow device, apply a positive measure of the patient's extremities to measure the blood pressure of the patient's blood pressure and conduct a frontal injection of blood flow to increase blood flow. Although somewhat inadequate blood flow increases compared to conventional devices, blood flow can be significantly increased, which can be selectively.

• Proceedings of the KSMRM Conference
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• 2003.10a
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• pp.73-73
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• 2003

목적： 피부조직과 같은 미세 인체구조 연구를 위해 고해상도 3T MRI 시스템에 적합한 고분해능의 RF surface coil을 개발하고 있다. In vivo 연구를 위한 여러 parameter를 최적화하여 기능영상에도 부합된다. 비침습적인 In vivo 검사에 의한 세포수준의 극 미세구조의 연구가 가능해짐으로써 과거 시행하던 침습적인 생검없이 각종질환의 진단적 접근이 병리학적 수준으로 향상되어 질병의 정확한 진단이 가능해지게 될 것이다.

• Proceedings of the KSLP Conference
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• 1998.11a
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• pp.182-182
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• 1998

연하작용이나 발성을 하는 동안 후두 및 주변의 움직임을 관찰하는 데에는 많은 어려움이 있었다. 최근에도 fluoroscopy, functional endoscopy, stroboscopy 등 다양한 방법이 사용되고 있지만, 이러한 검사 방법들은 모두 정상적인 기능을 억제하는 침습적인 방법이거나 실제 움직이는 모습이 아닌 허상을 보여주는 검사로 정확하고 자연스러운 움직임을 관찰하는데는 한계가 있었다. 저자들은 인체내의 구조물이 움직이는 것을 비침습적으로 실제 움직이는 그대로 확인할 수 있는 초음파검사가 후두질환에서 사용될 수 있는지 알아보기 위하여 본 연구를 시작하였다. (중략)

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2000.10a
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• pp.451-454
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• 2000

Invasive methode and Non-invasive methode are used in blood pressure measurement. The Invasive methode can Set the correct measured blood pressure but, it has patient feels uncomfortable. So most of cases use Non-invasive methode. The Oscillometric method is commonly apply to modem electric sphygmomanometer and using various algorithm. In this paper describe about a algorithm it control and to determinate the cuff pressure, and filtering that data for measure the blood pressure. The communicating with personal computer can pressure deflation is by Solenoid valve and it uses RS-232 system in packet communication. The main using algorithm for blood pressure measurements are maximum amplitude algorithm and oscillometric algorithm. MAA(maximum amplitude algorithm) has various measured oscillation it depend on patient's age, height, weight and arm circumference size. In this paper, 1 studied the various measured oscillation apply to characteristic ratio and can get the result of systolic blood pressure, diastolic blood pressure, mean blood pressure. It was not used same ratio to measuring oscillation. In the MAA(maximum amplitude algorithm), we hope for reduce the difference with the real blood pressure and the measured blood pressure, when it applied with various specific ratio.

• Journal of the Institute of Convergence Signal Processing
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• v.8 no.1
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• pp.6-14
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• 2007

The purpose of urodynamic investigation is to determine information on the function of the urinary system. One of the most frequently used measurement procedures in urodynamics is filling and voiding cystometry using invasive method. But in this method transurethral catheter is use and it makes patients uncomfortable. The aim of this study was to implement the system that could evaluate the function of urinary tract with noninvasive and comfortable method. Therefor in this study, a sensor and measuring system were implemented to measure uroflow, urophonography and noninvasive bladder pressure signal during urination for diagnosing the LUTS(lower urinary tract symptoms) using noninvasive method. The implemented system compose of the sensor parts, signal conditioning parts, system control parts using FPGA and PC monitoring program. For the evaluation of the implemented system, the simulation of system's control part was performed and the model system for the lower urinary system was designed. From the evaluation of the model system, the mean error rate of the uroflow measurement part was 1.08% and coefficient of variation was 1,48. And the mean error rate of the noninvasive bladder pressure measurement part was 2.41% and coefficient of variation was 2.81. urophongraphy signal analysis was accomplished in a time domain and frequency domain. Average RMS power was used in a time domain analysis, and MF was used in a frequency domain analysis. From the evaluation of the model system average RMS power and MF was dependent on the occlusion degree significantly and median frequency range of $60{\sim}160Hz$ was correlated with the occlusion.

• Journal of Life Science
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• v.25 no.6
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• pp.686-692
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• 2015

Cancer is subject to dynamic interactions between contrary immune reactions that drive both tumor growth and suppression. Forkhead box p3 positive T cells (Foxp3 positive T cells) might support tumor promotion, while CD8 positive T cells might protect the host. The present study examined the distributions of CD8- and Foxp3-positive T cells and CD8 positive T cells/ Foxp3 positive T cells ratio in skin squamous cell carcinoma (SCC) and its precancerous lesions; it also compared this with data for basal cell carcinoma (BCC). Iimmunohistochemical staining for CD8 and Foxp3 was conducted in 20 cases of SCC, Bowen's disease (BD), actinic keratosis (AK) and BCC. The BD and SCC cases exhibited significantly increased numbers of both CD8- and Foxp3-positive T cells in their advancing regions compared with the AK and BCC cases, and the BD cases exhibited significantly lower CD8 positive T cells / Foxp3 positive T cells ratio in these regions than did the AK and BCC cases. There was no significant difference in both T cells and the ratio between BD and SCC. The degree of both T cells infiltration differed between the advancing and central areas in SCC and BCC. Immune micro-environments differ between cutaneous squamous cell tumors and BCC and differ as well among tumor compartments.

• The Magazine of the IEIE
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• v.44 no.3
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• pp.51-57
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• 2017

• The Korean Journal of Medicine
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• v.99 no.2
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• pp.104-110
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• 2024

Helicobacter pylori (H. pylori) is a bacterium that colonizes the human stomach, leading to various gastrointestinal diseases including gastritis, peptic ulcers, and gastric cancer. There is no gold standard test that relies entirely on one method in H. pylori diagnosis. We must be aware of the pros and cons of various testing methods to perform an appropriate test according to the situation. Accurate diagnosis and eradication therapy are essential for disease management. Diagnostic methods include invasive techniques like tissue biopsy and rapid urease test, as well as non-invasive tests such as urea breath test, serology test, and stool antigen test. Each method has its advantages and limitations, requiring careful consideration in clinical practice. Understanding these diagnostic tools is crucial for effective H. pylori management and prevention of associated complications.

• Journal of The Korean Dental Society of Anesthesiology
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• v.11 no.1
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• pp.9-15
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• 2011

배경: 술 후 통증은 술 후 합병증의 발생가능성을 증가시키며 생체기능의 회복을 방해한다. 술 후 통증을 효과적으로 조절하기 위해선 통증의 정도를 객관적으로 평가하는 것이 필요하다. 술 후 통증은 수술의 침습도와 관련이 높을 가능성이 많다. 본 연구에서는 수술 침습도의 정도와 술 후 통증의 정도 사이의 상관관계를 확인하고자 한다. 방법: 총 153명의 환자를 수술의 침습도에 따라 4개의 그룹으로 나누었다(그룹 1: 악성종양 수술 (malignancy surgery), 그룹 2: 양악수술(bimaxillary surgery), 그룹 3: 양성 종양수술(benign cancer surgery) 그룹 4: 임플란트 & 골절 수술(implant & frature)) 수술이 끝나갈 무렵 fentanyl 700 ${\mu}g$, ketorolac 1,500 mg (총 용적 120 ml)가 포함된 자가통증조절장치를 정맥로에 연결하였다. 술 후 통증의 정도는 시각통증등급(visual analogue scale)을 이용하여 측정하였고 자가통증조절장치의 총 사용시간, 투여된 진통제의 양, bolus 투여 총 횟수를 측정하였다. 결과: 술 후 시각통증등급은 술 후 1일부터 3일까지 그룹 1, 2 군에서 유의하게 높았다. 또한 시각통증등급 3점 이상의 통증을 호소하는 환자의 비율 역시 그룹 1, 2 군에서 유의하게 높았다. 진통제 총 투여용량 및 자가로 주입한 진통제의 양 역시 그룹 1, 2군에서 3, 4 군에 비해 유의하게 높은 것을 확인하였다. 결론: 본 연구결과 외과적 수술의 침습도가 술 후 통증의 정도를 결정하는데 있어 중요한 요소임 을 확인하였다.

• Journal of Korean Critical Care Nursing
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• v.2 no.1
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• pp.69-80
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• 2009

Purpose: The purpose of this preliminary study was to describe the physical and psychosocial distress of critically ill patients undergoing noninvasive ventilation(NIV). Method: Open-ended question interviews were conducted with four patients using NIV. Considering the outcomes of the interviews, literature, and experts'opinions, a survey questionnaire was developed. Twenty patients in medical and surgical intensive care units answered the questions. Results: Through open-ended question interviews and survey, the patients using NIV reported feeling heavy, impotent feeling, pain, loss in feeling, loss in communication, and lack of sleep as physical distress and a loss in sense of time, pain, anxiety, mind of desiring to die, worry about family, and a sense of burden for medical-cure expenses as psychosocial distress. Conclusion: Critically ill patients undergoing NIV experience physical and psychosocial distress to artificial respiratory ventilation treatment. Further research should be performed with a large sample for generalization of the study result.