• Title/Summary/Keyword: 비주류

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3 Tesla MR Clinical Application: Advanced Neuroimaging

  • 손철호
    • Proceedings of the KSMRM Conference
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    • 2002.11a
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    • pp.50-56
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    • 2002
  • 최근 3-4년간 MR의 hardware와 software의 급격한 발전으로 마침내 작년 말에 3.0 Tesla whole body MR 장비가 미국 FDA의 공인을 받았다. 한국에서도 일찍부터 3T MR장비의 개발이 이루어 졌고 이미 설치되어 연구와 임상이 이용되고 있다. 여러 회사에서 개발 및 연구된 전신 3.0T MR 장비가 여러가지 가능성을 보이고 임상 도입 단계에 있지만 아직까지 실지 임상에서는 뇌신경계 분야가 주류를 이루고 있다. 지금 뇌신경계 분야에서 보편적으로 늘리 사용되고 있는 1.5T MR 장비는 모든 면에서 상당히 안정적으로 임상 및 연구에 이용되고 있다. 1-2년 전만 해도 3.0 T MR기기는 뇌신경계 영역에서도 임상적으로 늘리 사용되기에는 안정적인 면에서는 1.5T 기기에 비해서 떨어지는 것이 사실이었다. 그래서 주로 연구실 영역에서 많이 이용되고 있었다. 그러나 지금 본원에 설치 완료되어 임상에 적용한지 6개월 정도 이용한 예에서 보면 (about 2300 cases/6months) hardware, software적인 면에서 아직 조금의 불편함이 있지만 많은 부분이 충분히 인지되고 개선이 가능한 부분으로 거의 불편함이 사라질 것으로 기대되고 있고, 불편함을 넘을 수 있는 여러 가지 장점이 있다고 본다. 고자장 (>3.0 T) MRI의 매력은 자장에 비례적으로 SNR, spectral resolution이 높아지고, T1, BOLD등에 의한 대조도가 향상한다는 것이다. SNR의 증가는 temporal, spatial 분해능을 증가시키고, spectral resolution이 높아짐에 따라 MR spectroscopy상에서 주요 대사물질 이외 작은 대사물질에 관한 스펙트럼의 분석을 향상시킨다. 이처럼 고자장 MR은 근본적인 장점을 가지고 있고 이러한 장점이 고자장 MR 시대로 가야 할 이유을 모두 설명하고 있다고 생각된다.세포질등이 있으며, 이들중에서 lysosomes, peroxisomes, 그리고 미토콘드리아가 특정한 유전성 백질질환에 중요한 역할을 하는 것이 밝혀졌다. 이러한 질환들은 최소한 각 소기관에 의한 질환군으로 분류될 수 있다.SXR이 ER의 transactivation 효과를 약간 촉진한 반면 MDA-MB-231세포는 SXR을 제외한 CAR와 PPAR${\gamma}$에 의해 ER의 transactivation 효과가 약간 증가되는 경향을 보였다. 이러한 결과는 유방암세포에서는 CAR, SXR, PPAR${\gamma}$과 같은 xenobiotic nuclear receptor에 의한 ER transactivation 효과가 간암세포와는 다르게 나타나며, 유방암의 종류에 따라서 endogenous CAR, SXR, PPAR${\gamma}$수용체가 다르게 발현됨으로써 이들에 대한 반응이 서로 상이한 특징을 나타낼 수 있을 것으로 사료된다. 따라서 estrogen receptor에 의해 매개되는 estrogn의 전사활성조절기전이 표적세포에 따라 다른 경로를 포함 할 수 있음을 시사한다.서 흡착 능력이 우수하게 나타났으며, 황화수소는 펄라이트, 왕겨, 소나무수피에서 상대적으로 우수한 것으로 나타났으며, 혼합충전재는 암모니아의 경우 코코넛과 펄라이트의 비율이 7:3인 혼합 재료 3번과 소나무수피와 펄라이트의 비율이 7:3인 혼합 재료 6번에서 다른 혼합 재료에 비하여 우수한 것으로 나타났다. 4. 코코넛과 소나무수피의 경우 암모니아 가스에 대한 흡착 능력은 거의 비슷한 것으로 사료되며, 코코넛의 경우 전량을 수입에 의존하고 있다는 점에서 국내 조달이 용이하며, 구입 비용도 적게 소요되는 소나무수피를 사용하는 것이 경제적이라고 사료된다. 5. 마지막으로 악취제거 미생물균주를 접종한 소나무수피 50%와 펄라이트

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A study on Dohoe towns Kyonggi Province of the late Chosun Dynasty (朝鮮後期 京畿地方의 都會硏究)

  • ;Jang, Seung Il
    • Journal of the Korean Geographical Society
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    • v.29 no.2
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    • pp.183-200
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    • 1994
  • This research aims to introduce the theoretical basis of the studies of tourism resources, by review the research trends of tourism resources in the geography field. The geographical approaches to tourism resouces can be subdicided into 3 categories according to the subject. First, the classification of tourism resource types and the approach on the spatial distribution may be enumerated. This subject has been the object of the most interest and discussion to the geographers for tourism up to now. And from the viewpoint of contents, it has been developed by classifying the types of tourism resoures, which is based on the establishment of the range and standard of tourism resources and the spatial classification of types based on the distribution feature of the area. Second, the approach about cognition, preference and interpretation on the tourism resources as the background to induce tourism phenomenon and decide the tourism destination. Judging from the fact that most of this subject is starting from the behavioural study and that the right understanding and interpretation of tourism resource is the important factor to decide the preference degree of tourists, we have to have much interest about the field of tourism geoaraphy. Third, the development of tourism resources which is showing the active study recently and its influence and effect attendant upon it may be enumerated. Today, as the economic value of tourism is become important internationally, tourism resources are recognized as the important factor to induce the industrialization of tourism. And in the series of analytical studies related to it the interest has been transferred from the economic benefit analysis attendant upon tourism development including tourism resource and to the cultural, educational, environmental and psychological influence, etc. As the result of composite examination, for the geographical studies about tourism resources, the spatial scale and the contents are being subdivided and specialized. And in the side of subject and method of study, it is developing into the positive study based on the concrete data and the measuring and analytical frame.

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The Eire Risk Assessment in Compressed Natural Gas Buses & Gas Station (CNG 버스 및 충전소의 화재 위험도 평가)

  • Ko, Jae-Sun;Kim, Hyo
    • Fire Science and Engineering
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    • v.18 no.2
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    • pp.57-67
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    • 2004
  • The results of the risk assessing on general buses, consisting mainly of diesel-fueled buses, show that the frequency of the instantaneous release is 1.4${\times}$10$^{-3}$ /bus/year, from which the probability of the formation of fireball as a sub event becomes 1.7${\times}$104, and show that the leakage from the CNG-fueled buses is 0.002 event/year. Also, the frequency of gradual release due to a crack is estimated at 3.7${\times}$10$^{-3}$ /buses/year, and a subsequent probability at which this could lead to a jet flame as a sub event is 1.2${\times}$10$^{-3}$ This corresponds to 0.04event/year for the CNG-fueled buses. Dividing all the fired casualties by the running distance of diesel-fueled buses, the risk is 0.091 fire fatalities per 100-million miles. And the total fire risk fur CNG buses is approximately 0.17 per 100-million miles of travel. This means that CNG buses is twice or more dangerous than diesel buses. After all CNG buses are more susceptible to the major fires. In the aspect of the reliability of this study, generic models and the failure data used in assessing the risks of CNG buses are appropriate. However, more accurate physics-based models and databases should be supplemented with this study to provide the better results.

An Empirical Study on the Alternative Work Organization and Workers' Outcome - Focus on Lean Production - (대안적 작업조직 유형과 노동자 성과에 관한 실증적 고찰 - 제조업의 린 방식을 중심으로 -)

  • Son, Dong-Hui
    • Korean Journal of Labor Studies
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    • v.17 no.1
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    • pp.1-36
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    • 2011
  • The purpose of this study is to analyze the effect to financial outcome and workers' outcome, using the manufacturing industry database of Human Capital corporate Panel from Korea Research Institute for Vocational Education & Training. Especially, this study used the typology of Lean production and Autonomous team production, that are the typical form of alternative work organization, to analyze. In the case of domestic manufacturing industry, individual participation practices, that have the main characteristics such as QC or suggestion system, is expanded. Therefore, with the reference of Lean production, Autonomous Team Production and the Taylor system are compared and analyzed, considering the characteristics of Socio-technical System. As a result, it is showed that the Lean production and Autonomous Team Production as a alternative work organization are more positive about the organizational performance and workers' outcome than the taylor system. However, when Lean production and Autonomous Team Production are compared, it is showed unsignificant distinction to the effect of organizational performance. Meanwhile, Lean production showed more negative effect on the every dependent variables such as working hours, income, job satisfaction, and organizational commitment as workers' performance than the Autonomous Team Production. Although the common ideas and belief is that the Lean Production is superior for the quality and organizational performance improvement, it is implied the possibility that there is some damaged workers' performance on the hidden side of that mechanism.

Building robust Korean speech recognition model by fine-tuning large pretrained model (대형 사전훈련 모델의 파인튜닝을 통한 강건한 한국어 음성인식 모델 구축)

  • Changhan Oh;Cheongbin Kim;Kiyoung Park
    • Phonetics and Speech Sciences
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    • v.15 no.3
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    • pp.75-82
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    • 2023
  • Automatic speech recognition (ASR) has been revolutionized with deep learning-based approaches, among which self-supervised learning methods have proven to be particularly effective. In this study, we aim to enhance the performance of OpenAI's Whisper model, a multilingual ASR system on the Korean language. Whisper was pretrained on a large corpus (around 680,000 hours) of web speech data and has demonstrated strong recognition performance for major languages. However, it faces challenges in recognizing languages such as Korean, which is not major language while training. We address this issue by fine-tuning the Whisper model with an additional dataset comprising about 1,000 hours of Korean speech. We also compare its performance against a Transformer model that was trained from scratch using the same dataset. Our results indicate that fine-tuning the Whisper model significantly improved its Korean speech recognition capabilities in terms of character error rate (CER). Specifically, the performance improved with increasing model size. However, the Whisper model's performance on English deteriorated post fine-tuning, emphasizing the need for further research to develop robust multilingual models. Our study demonstrates the potential of utilizing a fine-tuned Whisper model for Korean ASR applications. Future work will focus on multilingual recognition and optimization for real-time inference.

Taxonomic Characterization and Safety of Nuruk Molds Used Industrially in Korea (국내에 유통되는 종국 곰팡이의 분류학적 특성 및 안전성)

  • Hong, Seung-Beom;Hong, Sung-Yong;Jo, Kyu-Hong;Kim, Young-Sik;Do, Jong-Ho;Do, Ji-Young;Noh, Seok-Beom;Yoon, Han-Hong;Chung, Soo-Hyun
    • The Korean Journal of Mycology
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    • v.43 no.3
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    • pp.149-157
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    • 2015
  • We examined taxonomic characteristics and safety of eight Nuruk molds that are widely used for making soybean paste, soy sauce and alcoholic beverages in Korea. HK1 from Hakyeong Fermentation Co., SW101 from Suwon Fermentation Co., CF1001, CF1002, CF1003 from Chungmoo Fermaentation Co. and KACC 93210 are yellow-Nuruk molds, and SW201 from Suwon Fermentation Co. and CF1005 from Chungmoo Fermentation Co. are white-Nuruk molds. Six strains of yellow-Nuruk molds were identified as Aspergillus oryzae. HK1, SW101, CF1001 and CF1003 of yellow-Nuruk molds have middle length of stipes ($711{\sim}1,121{\mu}m$), and CF1003 (for sake) produced less conidia and more hyphae than HK1, SW101 and CF1001 (for soybean paste). CF 1002 used for soy sauce has shorter stipes ($543{\mu}m$) and is clustered into IBLB-group based on omtA gene analysis although the other yellow-Nuruk molds are clustered into ICAo group. KACC 93210 isolated from traditional Korean Meju has very short stipes (average $270{\mu}m$), and showed velvety colonies although the others showed floccose colonies. The strain has different DNA sequences of omtA gene from other strains in NCBI GenBank as well as strains used in Korea, suggesting that it is unique from other strains published. SW201 and CF1005 of white-Nuruk molds were identified as Aspergillus luchuensis or A. luchuensis mut. Kawachii that is known as safe, non-toxigenic fungus. The six strains of yellow-Nuruk molds did not produce mycotoxins including aflatoxin, cyclopiazonic acid, and sterigmatocystin. Therefore, eight strains of Nuruk molds used for making soy sauce, soybean paste and alcoholic beverages in Korea were proved to be safe in this study.

Analysis of Actual State of Facilities for Pleurotus eryngii Cultivation - Based on Western Gyeongnam Area - (큰느타리버섯 재배사의 실태분석 - 서부경남지역을 중심으로 -)

  • Yoon Yong Cheol;Suh Won Myung;Yu Chan
    • Journal of Bio-Environment Control
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    • v.13 no.4
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    • pp.217-225
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    • 2004
  • This study was performed to provide the basic knowledge about the mushroom cultivation facilities. Classified current status of cultivation facilities in Gyeongnam province was investigated by questionnaire. The structure of Pleurotus eryngii cultivation facilities can be classified into the simple and permanent frame type. The simple frame structures were mostly single-span type, on the other hand, the permanent frame structures were more multi-span than simple structures. And the scale of cultivation facilities was very different regardless of structural type. But as a whole, the length, width and ridge height were prevailing approximately 20.0 m, $6.6\~7.0m$ and $4.6\~5.0m$ range, respectively. The floor area was about $132\~160\;m^2$, and floor was built with concrete to protect mushrooms from various harmful infection. The roof slope of the simple and permanent type showed about $41.5^{\circ}\;and\;18.6\~28.6^{\circ}$, respectively. The width and layer number of growing bed for mushroom cultivation were around $1.2\~1.6m$, 4 layers in common, respectively. Most of year round cultivation facilities were equipped with cooler, heater, humidifier, and ventilating fan. Hot water boiler was the most commonly used heating system, the next was electric heater and then steam boiler. The industrial air conditioner has been widely used for cooling. And humidity was controlled mostly by ultra-wave or centrifuging humidifier. But some farmers has been using nozzle system for auxiliary purpose. More then $90\%$ of the mushroom house had the independent environment control system. The inside temperature was usually controlled by sensor, but humidity and $CO_2$ concentration was controlled by timer for each growing stage. The capacity of medium bottle was generally 850 cc and 1100cc, some farms used 800 cc, 950 co and 1,250 cc. Most of mushroom producted has been usually shipped to both circulating company and joint market.

Seasonal Food Intake Status of the Long-lived Elderly People in Kyungpook Sung-Ju (경북 성주지역 장수노인의 계절별 식품섭취 상태)

  • 백지원;구보경;김규종;이성국;이혜성;이연경
    • Journal of the Korean Society of Food Science and Nutrition
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    • v.29 no.4
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    • pp.691-700
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    • 2000
  • The purpose of this study was to estimate food intakes of the long-lived elderly and to obtain the data for establishing dietary guidelines that may be recommended for the general population for the sake of longvity. The subjects of the study were 224 elderly people of age over 85 years living in Kyungpook Sung-Ju area who have no problem in daily living. The food consumption survey was carried out seasonally by the repeated 24-hr recall method for one year. The subject group for this study was composed of 58 males and 166 females, the average age being 87 years old. Food intakes of the winter were more than any other seasons. The mean daily total food intake per capita was 594.4g, 513.5 g (86.4%) from plant foods and 79.3 g(13.3%) from animal foods. The sequence of high intakes of food groups were cereals, vegetables, fruits, fishes, legumes and meats. Boiled white rice, beef soup, soybean paste soup, soybean paste stew, broiled yellow croaker, kimchi, ra myon and broiled noodles were consumed most frequently. In conclusion, the subjects consumed much more plants foods than animal foods and consumed more natural and seasonal foods than processed foods and also showed food habits of eating small meals. Dietary habits of eating small meals containing abundant amount of fresh plant foods might partially contribute to the longevity of the subjects.

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Characteristics of Ju-Back and Effect of Ju-Back Fertilizer on Growth of Crop Plants (주류생산 부산물인 주박의 특성 규명 및 주박이 작물생육에 미치는 영향)

  • Lee, Jung-Hoon;Park, Sung-Min;Park, Chi-Duck;Jung, Hyuck-Jun;Kim, Hyun-Soo;Yu, Tae-Shick
    • Journal of Life Science
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    • v.17 no.11
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    • pp.1562-1570
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    • 2007
  • This experiment was conducted to develop fertilizer which promotes plant growth as well as suppressing pathogenic fungi. The fertilizer was made from the mixture of Ju-Back (Korean rice wine cake) and indigenous rhizosphere-bacterium. The main ingredients of Ju-Back were investigated as 6.04% total nitrogen, 42.59% total carbohydrate, 1.01% available phosphate, 73.42% organic matter, 7.72% potassium oxide, 1.35% calcium oxide, 0.53% magnesium oxide. The enzyme activities of Ju-Back were estimated to be 980 units/g for ${\alpha}-amylase$, 300 units/g for glucoamylase, and 1800 units/g for acid pretense. Indigenous rhizosphere bacteria which produced antifungal agent were isolated from soil, and was selected KMU-13 strain which can antagonize against various plant pathogenic fungi (Botrytis cinerea KACC 40573, Sclerotinia sclerotiorum KACC 41065, Fusairum oxysporum KACC 40052, Pythium aphanidermatum KACC 40156, Phytophthora capsici KACC 40476 and Glomerella cingulata KACC 40299). KMU-13 strain was identified as Bacillus subtilis KMU-13 by biochemical and 16s rDNA analysis. The organic fertilizer was made as prototype which was composed 20% Ju-Back, 70% carrier, 9.7% microorganism cultivated solution, 0.3% trace-element. We also investigated an application of fertilizer using Ju-Back for cultivating lettuce (Lactuca sativar) which were grown in three soil conditions that had chemical fertilizer, barnyard manure, lime power, urea, potassium chloride and superphosphate as a control, the whole quantity (80 kg/10a) of posted fertilizer with the control and the half quantity (40 kg/10a) with the control. The growth characteristics were examined and analysed with several weeks interval from 3 weeks to 8 weeks on head length (cm), head width (cm/head), number of leaf and fresh weight (g/plant). The results are summarized as follows. The head width and fresh weight of lettuce were the highest at posted fertilizer 1 (whole quantity) was applied chemical, organic matter (Ju-Back) and carrier. The head length was the highest at posted fertilizer 2 (whole quantity) was applied Ju-Back only.

A Study on the Meaning and Spatial Characteristics of the Chinese Zhuozhengyuan from the Tablets (편액을 통해 본 중국 졸정원의 의미와 공간 특성)

  • Ham, Kwang-Min;Son, Yong-Hoon;Li, Shu-Hua
    • Journal of the Korean Institute of Traditional Landscape Architecture
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    • v.35 no.4
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    • pp.98-109
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    • 2017
  • The results of this study attempting to graft to the space by cognizing and categorizing the characteristic of the under-toned private property to the tablets of the Zhuozhengyuan are as follows. The tablet of Zhuozhengyuan was typed into three groups. In the A group, the frequency of artificial elements including the top, ship, and head was high, and the main emphasis was on the elegance and integrity spirit that the Sunbi(classical scholar) had to have. It has a characteristic of good architects such as pavilion and Nu(樓) is included and as it is adjacent to the water surface the one side of the building is integrated to the water surface. The B group is characterized mainly by the fact that the scenery is portrayed through the climatic factors including rain, wind, and snow, or the scene atmosphere and it is located at the top of the summit which is good for viewing the scenery. In the C group, plant elements such as lotus, magnolia, plum, and bamboo appeared frequently, and various buildings such as pavilion, Kwan(館), Gak(閣) and Dang(堂) belong to this structure. The structure has the characteristic of integrating directly with the water surface or putting the terrace between and scattering throughout the whole garden. Furthermore, this study identified area characteristics based on the frequency of the tablet type. In the west area, Group A is mostly distributed and the humor and concept implied in the tablet, combined with the shape and location of the scenery, viewpoint of the viewer, and the composition of the landscape, improved the orderliness of the space, which led to expand the scope of the enjoyment to the entire space. Meanwhile, in the middle area, tablets of Group C are mostly distributed, and the unique characteristics and shapes of the woody plants that were used as the name of the tablet were connected with various buildings including pavilion, Dang, Kuan, and Gak, improving the unique identity of the space and forming connection with the world of ideas through unity and independence.