• Journal of Nutrition and Health
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• 제41권8호
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• pp.767-775
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• 2008

Uncoupling protein-1 (UCP-1) plays a major role in thermogenesis at brown adipose tissues and has been implicated in the pathogenesis of obesity and metabolic disorders. The purpose of this study was to estimate the effects of A-3826G polymorphism in 117 Korean prepubertal children aged 8-11 years olds. Anthropometry by bioelectrical impedance analysis method, plasma lipid profiles by auto-biochemical analyzer and UCP-1 genotyping by PCR-RFLP were done. The frequencies of UCP-1 genotypes were AA; 17.7%, AG; 57.8%, GG; 26.6%. The frequencies of each G allele (55.5%) was similar to Japanese's (49%) and higher than Caucacian's (25%). No correlation UCP-1 polymorphism and BMI (kg/$m^2$) or the degree of obesity described by the relative percentiles of the standard weight according to height in prepubertal children. However, plasma total- and LDL-cholesterol were significantly increased in G allele when sex, age and weight were adjusted. Our results suggested that G allele of UCP-1 gene was stronger risk factors in hyperLDLcholesterolemia than A allele. This impact might be progressed as the precaution against the revalence of obesity based-metabolic disease.

• Fashion & Textile Research Journal
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• 제14권2호
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• pp.269-276
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• 2012

The aim of this study is to develop clothing size system according to each size interval for obese girls aged 10~12 by classifying the upper bodies. The criteria for subjects in this study were girls who had over 1.46 of the R$\ddot{o}$hrer Index. A total of 229 schoolgirls who met these criteria were enrolled. Results are as follows; 1st, 5 factors were extracted by factor analysis and 3 clusters were categorized by cluster analysis, cylinder-type, inverted triangle-type and inverted trapezoid-type. And 2nd, as a consequence of size system establishment, the basic body sizes and reference body sizes were different according to types even in commonly-appeared size names at sections of respective types. The research findings above suggest that it is necessary to figure out the obesity types according to height and bust girth sizes representing basic sizes and to design the patterns in consideration of the characteristics of obese body shapes. And it may be used as a basic data to decide the desirable output of production according to respective body types.

• The Journal of Internal Korean Medicine
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• 제26권1호
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• pp.119-128
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• 2005

모든 알레르기 반응의 중심축이 되는 비만세포는 주로 피부, 위장관 및 호흡기관의 점막에 분포하고 있다. 활성화된 비만세포는 즉각형 알레르기 반응을 일으키는 여러 인자들을 방출시키게 된다. 方藥合編(방약합편)에 따르면 蔘蘇飮(삼소음)은 알레르기 鼻炎(비염), 發熱(발열), 風寒(풍한), 頭痛(두통), 기침에 效能(효능)이 있는 處方(처방)이다. 본 硏究(연구)는 蔘蘇飮(삼소음)의 肥滿細胞(비만세포) 의존성 아나필락시 반응(anaphylactic reaction)에 대한 藥理(약리) 效果(효과)를 조사하기 위한 것이다. 蔘蘇飮(삼소음)은 compound 48/80으로 유발되는 전신성 아나필락시 쇼크(systemic anaphylactic shock)와 耳介(이개) 浮腫(부종) 反應(반응)(ear swelling response)을 농도 의존적으로 억제하였다. 蔘蘇飮(삼소음)을 0.1, 1 mg/ml로 전처리 하였을 때, 흰쥐 복강 肥滿細胞(비만세포)(rat peritoneal mast cells, RPMCs)에서 compound 40/80에 의해 유발되는 히스타민 분비는 감소하는 것으로 나타났다. 또한 蔘蘇飮(삼소음)은 anti-dinitrophenyl IgE에 의해 활성화 된 수동 피부 아나필락시(passive cutaneous anaphylaxis, PCA)를 농도 의존적으로 抑制(억제)하였다. 결론적으로 蔘蘇飮(삼소음)은 肥滿細胞(비만세포) 의존성 즉각형 알레르기 反應(반응)을 抑制(억제)하여, 항 아나필락시 활성(anti-anaphylactic activity)을 가지는 것으로 보여 진다.

• Journal of Korean Medical classics
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• 제24권6호
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• pp.131-133
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• 2011

비단은 비만을 기초로 한 당뇨병의 초기상태이며, 당내량 손상(IGT)은 당대사가 정상과 당뇨병 사이에 있는 아건강 상태를 말한다. 비단의 병인병기와 임상특징은 당내량 손상과 기본적으로 일치한다. 당내량 손상은 비만환자가 비단을 거쳐 당뇨병으로 발병되는 자연발전과정으로 비단과 당내량 손상의 공통적인 발병인소는 비만이며, 그 병리중심은 비위(脾胃)기능실조로 인한 당내량 이상으로 중의(中醫) 증형(證型)에 있어 허실(虛實)변화가 있다. 비단과 비만형 IGT 증후, 병리방면에서의 발생과 발전의 작용을 탐구하여 조기에 중약(中藥)을 사용하면 체중을 감소시키고 더 나아가 당뇨병을 예방하는데 중요한 임상의의가 있다.

• The Journal of the Institute of Internet, Broadcasting and Communication
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• 제18권1호
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• pp.119-127
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• 2018

The formal data used in the business is managed in a table form without normalization due to lack of understanding and application of data modeling. If the balance of the database design is destroyed, it affects the speed of response to the data query, and the data obesity becomes high. In this paper, it is investigated how data obesity improved through database design through optimized data modeling. The data query path was clearly visualized by square design through data modeling based on the relationship between object (data) and object, from the radial and task - oriented isolation design where data obesity is excessive. In terms of data obesity, the obesity degree of the current research support database was 57.2%, but it was 16.2% in the new research support database, and the data obesity degree was reducd by 40.5%. In addition, by minimizing redundancy of data, the database has been improved to ensure the accuracy and integrity of the data.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 한국정보통신학회 2017년도 춘계학술대회
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• pp.730-732
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• 2017

While the short term effect of diet and exercise therapy has been proven, there has still been a problem of its long term effect. So, researchers has utilized behaviour modification therapy. It is expected to lead to natural weight loss by modifying wrong dietary life patterns and practices. However, this approach has turned out to be a more effective method for weight maintenance than loss of weight. In spite of its strength, as a matter of fact, persistent and continuous effort for weight management has not worked properly. This study proposes an artificial intelligence approach with the advantages of behaviour modification therapy, overcoming current approaches which is goal-driven and too uniform. For this, we plan to develop a health management program in which users get the messages that are customized for themselves according to different situations so that it can promotes persistent effort for exercise. Here, customized messages are handled by AI techniques, which eventually promotes soft persuasion, encouragement, and motivation.

• Science of Emotion and Sensibility
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• 제8권1호
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• pp.37-45
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• 2005

This paper reports the remedial effect measurement of an obesity remedy machine for home use which has been developed by H Co. and the authors. It is expected that the machine enhances it's remedial effect and usability by utilizing medium frequency and thermotherapy belt etc. In order to measure it's remedial effect, a clinical experiment, which participates eight young female subjects, has been conducted for one month. The experiment includes the measurements on the changes of Gas-Exchange Responses of subjects through Cardio-Pulmonary Exercise Testing. The experimental results show that the obesity remedy machine helps the subjects to reduce their weights, fat rates, and $VCO_2s$. Thus, it turns out that the machine can be a good candidate for medical treatment on the obesity.

• 건강소식
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• 제36권9호
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• pp.40-41
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• 2012

흔히 뱃살이 나오는 것으로 표현되는 복부비만은 배에 과도한 지방이 축적된 상태로, 한국인의 허리둘레 기준으로는 남자 35.4인치(90cm), 여자 33.5인치(85cm) 이상인 경우에 해당한다. 지금까지 복부비만은 대사증후군의 일환으로서 당뇨병 발생 위험이나 심혈관계 질환의 위험을 높이는 것으로 알려져 왔으나 최근의 연구 결과에 따르면 허리둘레가 독립적으로 제2형 당뇨병 발병 위험과 밀접하게 연관된 것으로 나타났다.

• The Monthly Diabetes
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• 통권169호
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• pp.10-13
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• 2003

• The Monthly Diabetes
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• 통권77호
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• pp.24-28
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• 1996