• Title/Summary/Keyword: 비대칭 Reformatsky 반응

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Enantioselective Reformatsky Reaction Using Cinchona Alkaloids as Chiral Ligands (Cinchona 알칼로이드를 키랄 리간드로 이용한 비대칭 Reformatsky 반응)

  • Park, Doo-Han;Choi, Ho-Jin;Lee, Sang-Gi
    • Journal of the Korean Chemical Society
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    • v.47 no.6
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    • pp.597-600
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    • 2003
  • Cinchona alkaloids (1-4) were used as chiral ligands for the enantioselective Reformatsky reactions. The order of addition of the Reformatsky reagent to ligands was the important factors for the chiral induction. The ratio of Reformatsky reagent to ligand and aldehyde was also effected on the reaction yields.