• Journal of Nutrition and Health
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• v.42 no.6
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• pp.516-522
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• 2009

In this study, the effects of a mixture consisting of vitamin E, vitamin C, pycnogenol and evening primrose oil (mixture LGNC-5) on ultraviolet light (UV) induced pigmentation and wrinkle reductions of normal healthy volunteers were studied. In a double-blind placebo-controlled study, each of 54 subjects took daily either 4 capsules of the mixture LGNC-5 (Group ABC; 282.5 mg/capsule) or placebo (Group Ganada). We irradiated 2.5 MED UV on the upper arms and measured the whitening effect by colorimeter-based L value. The level of wrinkle reduction was determined by image analysis using skin replica around the crow' feet, and the level of serum vitamin E was determined at baseline and 12 weeks. After 12-week oral administration, the treated group showed a significant reduction in skin pigmentation and wrinkles compared with the placebo group (p = 0.011 and p = 0.000005, respectively). Also, the level of serum vitamin E was significantly increased in the treated group after 12-week oral adminstration of the mixture compared with that in the placebo group (p = 0.0001). In conclusion, 12-week oral administration of LGNC-5 as a dietary supplement could be effective to reduce both UV induced pigmentation and skin wrinkle without side effects.

• Radiation Oncology Journal
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• v.25 no.3
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• pp.170-176
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• 2007

Purpose: To determine the role of radiotherapy for the treatment of portal vein thrombosis (PVT) from hepatocellular carcinoma (HCC). Material and Methods: A retrospective analysis was performed on 70 patients that had been diagnosed with HCC and were treated with three-dimensional conformal radiotherapy (3D-CRT) for the PVT. The radiation dose ranged from 40 Gy to 60 Gy (median dose: 48 Gy) and the biological effective dose (BED) ranged from 31.3 Gy to 78.0 $Gy_{10}$ (median dose: 61.6 $Gy_{10}$). Response was determined by measuring the extent of the PVT on a CT image at 0, 1 and 3 months after completion of the radiotherapy. The median follow-up period was 9 months. Results: The response rate was 47.1% (33 patients), with two patients (2.9%) showing a complete response, 31 patients (44.3%) showing a partial response, and 35 patients (50%) showing stable disease or no response. The 1-year progression-free survival rate was 60%, and the median progression-free survival time was 17 months. The median overall survival time was 11 months, the median survival time in the responders was 15 months and in the nonresponders was 8 months (p=0.032). Four patients (5.7%) had transient liver function impairment during treatment. Radiation induced liver disease (RILD) was observed in only one patient (1.4%). Conclusion: Three-dimensional conformal radiotherapy for the treatment of PVT from advanced HCC was a relatively effective and safe method.

• Journal of the Korean Society for Marine Environment & Energy
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• v.10 no.2
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• pp.67-85
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• 2007

A three-dimensional hydrodynamic model with the fine grid is applied to simulate the barotropic tides, tidal currents, residual currents and salinity dispersions in the Yellow Sea and the East China Sea. Data inputs include seasonal hydrography, mean wind and river input, and oceanic tides. Computed tidal distributions of four major tides($M_2,\;S_2,\;K_1$ and $O_1$) are presented and results are in good agreement with the observations in the domain. The model reproduces well the tidal charts. The tidal residual current is relatively strong around west coast of Korea including the Cheju Island and southern coast of China. The current by $M_2$ has a maximum speed of 10 cm/s in the vicinity of Cheju Island with a anti-clockwise circulation in the Yellow Sea. General tendency of the current, however, is to flow eastward in the South Sea. Surface residual current simulated with $M_2$ and with $M_2+S_2+K_1+O_1$ tidal forcing shows slightly different patterns in the East China Sea. The model shows that the southerly wind reduces the southward current created by freshwater discharge. In summer during high runoff(mean discharge about $50,000\;m^3/s$ of Yangtze), low salinity plume-like structure(with S < 30.0 psu) extending some 160 km toward the northeast and Changjiang Diluted Water(CDW), below salinity 26 psu, was found within about 95 km. The offshore dispersion of the Changjiang outflow water is enhanced by the prevailing southerly wind. It is estimated that the inertia of the river discharge cannot exclusively reach the around sea of Cheju Island. It is noted that spatial and temporal distribution of salinity and the other materials are controlled by mixture of Changjiang discharge, prevailing wind, advection by flowing warm current and tidal current.

• Horticultural Science & Technology
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• v.31 no.6
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• pp.821-827
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• 2013

The purpose of this study was to investigate the effects of three kinds of horticultural activities (HAs) on attention concentration of elementary students. We selected 20 students using a Wee Class counseling office at J elementary school in Yeongcheon, and divided them into experimental and control groups composed of ten students each. The experimental group participated in three HAs including flower arrangement, planting, and pressed flower. Each HA was composed of three sessions and a session proceeded for a week. For the examinations of attention concentration, two groups responded the questionnaires before a week of the first session and at the end of the 9th session, only the experimental group participated in the measurement using grid by Harris before a week of the first session and at the end of each HA every week. The results of questionnaire survey showed that the scores of problem in emotion and problem in controlling, and the total score decreased 9.2, 7.8, and 19.0 points, respectively (P < 0.05), indicating that the attention concentration of the experimental group improved compared with the control. In the measurements using grid by Harris, the flower arrangement, planting, and pressed flower activities increased the scores by 2.22, 2.49, and 2.41 points compared with the pre-HA of 6.00, respectively (P < 0.05), that means the improvements of attention concentration. At the post-HAs, the flower arrangement, planting, and pressed flower activities increased the scores by 1.12, 1.39 and 1.31 points compared with the control group of 7.10, respectively (P < 0.05). In conclusion, the indoor HAs improved the attention and concentration of elementary students irrespective of kind of activities.