• 월간산업보건
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• s.39
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• pp.49-49
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• 1991

• Transactions of the Korean Society of Mechanical Engineers B
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• v.36 no.4
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• pp.419-424
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• 2012

In addition to respiration, the nose performs three other major physiological functions-air-conditioning, filtering, and smelling. On the basis of our experience in experimental investigations of nasal airflows in normal and abnormal nasal cavity models, airflows in the normal model and three artificially deformed models, which simulate the results of surgical treatments (inferior turbinectomy), are investigated by PIV and CFD. The left cavities of all three models are normal, and the right cavities are modified as follows: (1) excision of the head of the inferior turbinate, (2) resection of the lower fifth of the inferior turbinate, and (3) resection of almost the entire inferior turbinate. The use of high-resolution CT data and careful surface rendering of three-dimensional computer models with the help of an ENT doctor provide more sophisticated nasal cavity models. Nasal airflows for both normal and deformed cases are also compared.

• Journal of the korean academy of Pediatric Dentistry
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• v.25 no.4
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• pp.782-787
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• 1998

The treatment for pediatric dental patient has become more complex than the previous, because patients of pediatric dentistry, younger than the previous, and they were often combined with systemic disease. And, the importnace of conscious sedation has been increased by this time for this reason. In a variety of CNS depressants, newly developed imidazobenzodiazepine (midazolam) is well known as a safe and effective medicament. It has a rapid onset, minimized cardiovascular depression and various possible administering, route, so it is commonly used for the conscious sedation of pediatric dental patients. Recently, "intranasal drop-in method" draws attention for its safety, but discomfort during administration and posterior dripping through pharynx diminish its popularity. Now more advanced method for intranasal administration is introduced for conscious sedation for pediatric dental patients, it is "intranasal spray" with aerosol form of medicament. With this method, we can achieve some benefits as belows : 1. Diminished discomfort during intranasal spray than nitranasal drop-in. 2. Rapid osnet and reduction than intranasal drop-in. 3. Eliminatin of adverse reaction, such as rhinorrhea. 4. More improved behavior rating scale.

• Proceedings of the KOR-BRONCHOESO Conference
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• 1982.05a
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• pp.15.2-15
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• 1982

Inverted papilloma arising from mucous membrane of the nasal cavity and paranasal sinuses is very rare benign neoplasm. Ward first described nasal papilloma in 1854, but its infrequent occurrence has delayed accurate understanding. This tumor was histologically benign neoplasm and clinically malignant, because it is locally invasive with extensive bone erosion at times and it shows a high incidence of local recurrence, and change of squamous cell carinoma was sometimes found. Recently, the authors have experienced a case of inverted pailloma with focal squamous cell carcinoma change which occupied the right side of the nsal cavity and maxillary sinus in a 48-year-old male. The tumor mass was removed surgically through intranasal and Caldwell-Luc's approach, and then was treated with systemic administration of Bleomycin, local spray of 5-FU and radiotherapy ($Co^{60}$). We report our case with review of current literatures.

• Journal of Korean Academy of Oral and Maxillofacial Radiology
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• v.23 no.2
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• pp.347-355
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• 1993

In the pigmented tumors, the diagnosis of malignant melanoma is not alway easy. Primary mucosal melanoma arising in the nose and paranasal sinuses is a rare disease with a generally poor prognosis. Melanoma in these area is frequently silent at the onset and produces insufficient symptoms to force the patient to the physician in the early stages of the disease. The importance of early recognition of melanoma by the physician is emphasized. We have an experience a case of primary malignant melanoma of the nose and paranasal sinuses in a 36-year-old female and present this case with a brief review of literatures.

• Journal of Yeungnam Medical Science
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• v.19 no.1
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• pp.28-38
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• 2002

Background: Chronic paranasal sinusitis is one of the most common disease in the otorhinolaryngologic field. Endoscopic sinus surgery is treatment of choice in chronic paranasal sinusitis. The aim of this study was to evaluate objective and subjective treatment outcomes of endoscopic sinus surgery in adult chronic paranasal sinusitis with or without polyp. Materials and Methods: We reviewed 84 adult patients underwent endoscopic sinus surgery by one surgeon from June 1999 to June 2000, prospectively. We analyzed preoperative and postoperative subjective symptom scores and acoustic rhinometric results. Results: Fifty cases were male and thirty four cases female. The average age was of 33 year-old (range: 17 to 66 years). There was significantly improvement of symptom scores in postoperative 3 months and 6 months compared with preoperative symptom scores. There was significantly increased postoperative total volume of nasal cavity. When we compared high score group with low score group, there was statistically significant improvement of symptom scores between preoperative stage and postoperative 3 months in radiologic grading group. Conclusions: Endoscopic sinus surgery is considered to be effective for the treatment of chronic paranasal sinusitis. It seems to be helpful to employ subjective symptom score system and objective total volume change of nasal cavity through acoustic rhinometric test to analyze effectiveness of endoscopic sinus surgery. In this study, the most important preoperative factor of sinus surgery outcomes is radiologic grading system.

• Pediatric Infection and Vaccine
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• v.16 no.2
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• pp.131-141
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• 2009

Purpose : In February 2007, an outbreak of methicillin-resistant Staphylococcus aureus (MRSA) skin and soft tissue infections occurred in two newborns in the neonatal unit of Sahmyook Seoul Hospital. We performed this study to investigate the characteristics of MRSA nasal carriage among neonatal unit staffs and the effective infection control measures. Methods : Nasal swab specimens were obtained from the neonatal unit staff for the presence of MRSA. MRSA-colonized staffs were offered decolonization therapy with oral trimethoprim-sulfamethoxazole or 2% mupirocin ointment. Every 2-4months after decolonizaton, repeat nasal swab specimens were obtained. Also, samples from the neonatal unit environment and room air were collected. Results : Successful decolonization was achieved in 92% of the cases in 2 weeks after decolonization therapy, but most of the staffs were recolonized after several months. The nature of antibiotic susceptibility was changed from multi-drugsusceptible to multi-drug-resistant. The most frequently contaminated objects were dressing carts, computer keyboards, bassinets and washbowls. In environmental cultures using the settle microbe count method, the colony counts were decreased significantly at the last study period compared with the first study period in the neonatal room, breastfeeding room, service room, and dressing room (P <0.05). Conclusion : Effective control of sustained MRSA transmission within an institution may require prompt identification, treatment, and monitoring of colonized and/or infected staffs. However, nasal decolonization therapy may induce multi-drugresistant MRSA infection and had no effect on decreasing the MRSA nasal carriage rate in our study. Other factors might be more important, such as improving staff education, increasing hand hygiene practices, and environmental sterilization for controlling MRSA infections.

• Proceedings of the KSLP Conference
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• 1997.11a
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• pp.253-253
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• 1997

비폐색이 있는 경우 음성이 변하는 것을 쉽게 느낄 수 있지만, 비폐색 때의 음향학적인 특성에 대하여 알려진 바를 찾기는 쉽지 않다. 저자들은 인위적으로 비폐색을 유발하여 비폐색 부위에 따른 비강자음의 음향학적 변화특성을 파악하고 비음도의 변화 정도를 비교하고자 하였다. 정상비음도를 보이는 성인남녀 각 10명을 대상으로, 2ml의 부피를 갖도록 수술용장갑에 Merocel$^{\circledR}$을 넣은 뒤, 이를 이용하여 ostiomeatal unit(OMU)을 중심으로 전후상하 4부위의 인위적인 비폐색을 유발하여, 비폐색 전과 후의 부위에 빠른 차이틀 비교하였다. /나나/의 발성을 각 조건에서 3회 실시하여, 모음중간의 /ㄴ/중 (CVCV) 안정된 spectorgram소견을 보이는 부위를 선택하여, 해당구간의 제1, 제2, 제3 음형대와 각각의 bandwidth 평균값을 남녀별로 비교하였고, 표준비음비율이 알려진 rabbit, baby, mama 문장을 이용하여 비음비율을 비교하였다. 남녀모두 비폐색전에 비하여 OMU의 앞쪽부위를 막은 경우에 제1음형대가 가장 뚜렷하게 감소되었으며, 비음비율의 유의한 감소를 보였다. 비폐색이 있는 경우, 비강자음 /ㄴ/은 제1음형대를 중심으로 주요변화가 일어남을 알 수 있었으며, 비폐색 부위에 따라 비음비율이나 제1음형대 감소의 정도가 다름을 알 수 있었다.

• Proceedings of the KIEE Conference
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• 2015.07a
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• pp.1347-1348
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• 2015

본 논문에서는 기상레이더 데이터에서 섞여있는 강수에코 및 비강수에코를 분류하기 위하여 Interval Type-2 FCM based RBFNN의 도움으로 사례 및 에코 분류기의 설계를 제안한다. 학습과 테스트 데이터는 현재 기상청에서 사용하는 UF radar data를 사용하였으며, 사례 분류기와 에코패턴 분류기의 데이터를 각각 생성한다. 전처리 과정인 사례 분류를 통하여 강수사례 혹은 비강수사례를 분류하여 강수사례일 경우 에코패턴분류를 진행하며, 비강수사례일 경우 데이터에 관측된 모든 반사도 값을 제거한다. 사례 및 에코 분류기는 Interval Type-2 FCM based RBFNN을 통하여 패턴분류를 진행하며, 패턴분류 성능을 확인한다. 또한 후반부 파라미터의 동정 시, 각 규칙에 파라미터를 전역적으로 구하는 LSE와 각 규칙에 대한 파라미터를 독립적으로 구하는 WSLE의 비교연구를 수행한다. 분류기의 성능을 확인하기 위하여 사례 분류 후 에코패턴분류의 결과는 현재 기상청에서 사용하고는 품질검사(QC) 데이터와 비교하여 평가하였다.

• Proceedings of the KOR-BRONCHOESO Conference
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• 1996.04a
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• pp.87-87
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• 1996

상기도 점막의 분비세포와 이로부터 분비되는 점액은 각 부위에 따라 형태학적, 기능적 특성이 다르다. 특히 후두의 성대부위는 발성시 고속의 마찰진동이 있게 되어 성대상피를 보호하기 위한 윤활제 역할의 점액이 필요하다. 점탄성과 밀접한 연관이 있는 점액당단백질 분비세포의 조성비율과 밀도를 알기 위해서 개 10마리의 후두, 기관, 상악동, 비강점막을 채취하여 periodic acid-Schiff, alcian blue 1.0, alcian blue 2.5, high iron diamine-alcin blue염색을 하여 다음과 같은 결론을 얻었다. 1. 후두점막에서 선포의 밀도는 성문부의 후두실 상부에서 가장 높았다. 2. 후두점막에서 점액세포의 조성은 성문상부에서 가장 높았고, 장액세포의 조성은 성문부에서 가장 높았다. 3. 황화점액의 조성비는 성문부가 성문상부, 성문하부보다 유의하게 높았고, 후두의 세 부위와 기관에서 상악동과 비강보다 유의하게 높았다. 4. 타액점액의 조성비는 성문부에서 성문하부보다 유의하게 낮았으며, 성문부는 성문상부에 비해서도 통계적 유의성은 없었으나 낮은 경향을 보였다. 5. 상기도의 각 부위에서 당단백질의 조성비는 모든 부위에서 중성점액이 가장 높았고 산성점액중 성문부에서는 황화점액이 타액점액보다 유의하게 높았으며 성문하부, 상악동, 비강에서는 타액점액이 황화점액보다 유의하게 높았다. 이상의 결과에서 성문부에서 나타나는 높은 장액세포의 비율과 점액당단백질 조성의 특징이 성문부 점액의 성대운동에 대한 윤활작용에 적합한 생리적 역할을 담당하는 것으로 생각된다.