• Title/Summary/Keyword: 불안정 현상

검색결과 498건 처리시간 0.027초

Treating Idiopathic Parkinson's Disease with Bonoesikpungjigyeong-tang: A Case Study on "Delayed On" and "Wearing Off" Phenomena after Long-term Levodopa Intake (레보도파 약효 지연 현상 및 약효 감소 현상으로 인한 자세불안정 및 전신탈력감을 호소하는 특발성 파킨슨병 환자에 대한 보뇌식풍지경탕 치험 1례)

  • Siyun Sung;Dabin Lee;Seongeun Huh;Sunghee Hong;Ye-chae Hwang;Gyeongmuk Kim;Han-Gyul Lee;Sang-Kwan Moon;Woo-Sang Jung;Seungwon Kwon
    • The Journal of Internal Korean Medicine
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    • 제45권2호
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    • pp.219-233
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    • 2024
  • A 69-year-old female diagnosed with idiopathic Parkinson's disease and treated with anti-Parkinsonian medications, including levodopa, for 7 years presented with complaints of wearing-off phenomenon and delayed onset of medication efficacy, resulting in postural instability and feeling of severe exhaustion. The patient underwent a 50-day course of treatment with Bonoesikpungjigyeong-tang formula. The effects of the treatment were evaluated by recording the average time to onset of medication efficacy, the average time to medication wearing-off, and discomfort due to wearing-off phenomenon. Postural instability was assessed using the Numeric Rating Scale (NRS). The patient's overall quality of life was assessed using the EQ-5D-3L. After 50 days of treatment, the average time to onset of medication efficacy decreased, and the average time to medication wearing-off increased. Discomfort due to wearing-off phenomenon and postural instability decreased. This case suggests that Bonoesikpungjigyeong-tang might be an alternative for improving discomfort caused by long-term levodopa intake.

Hue Shift Model and Hue Correction in High Luminance Display (고휘도 디스플레이의 색상이동모델과 색 보정)

  • Lee, Tae-Hyoung;Kwon, Oh-Seol;Park, Tae-Yong;Ha, Yeong-Ho
    • Journal of the Institute of Electronics Engineers of Korea SP
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    • 제44권4호통권316호
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    • pp.60-69
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    • 2007
  • The human eye usually experiences a loss of color sensitivity when it is subjected to high levels of luminance, and perceives a discrepancy in color between high and normal-luminance displays, generally known as a hue shift. Accordingly, this paper models the hue-shift phenomenon and proposes a hue-correction method to provide perceptual matching between high and normal-luminance displays. The value of hue-shift is determined by perceived hue matching experiments. At first the phenomenon is observed at three lightness levels, that is, the ratio of luminance is the same between high and normal-luminance display when the perceived hue matching experiments we performed. To quantify the hue-shift phenomenon for the whole hue angle, color patches with the same lightness are first created and equally spaced inside the hue angle. These patches are then displayed one-by-one on both displays with the ratio of luminance between two displays. Next, the hue value for each patch appearing on the high-luminance display is adjusted by observers until the perceived hue for the patches on both displays appears the same visually. After obtaining the hue-shift values, these values are fit piecewise to allow shifted-hue amounts to be approximately determined for arbitrary hue values of pixels in a high-luminance display and then used for correction. Essentially, input RGB values of an image is converted to CIELAB values, and then, LCh (lightness, chroma, and hue) values are calculated to obtain the hue values for all the pixels. These hue values are shifted according to the amount calculated by the functions of the hue-shift model. Finally, the corrected CIELAB values are calculated from corrected hue values, after that, output RGB values for all pixels are estimated. For evaluation, an observer's preference test was performed with hue-shift results and Almost observers conclude that the images from hue-shift model were visually matched with images on normal luminance display.

The Opening Efficiency of Anchovy Boat Seine (권현망어구의 전개성능)

  • An, Yeong-Su;Jang, Chung-Sik;Lee, Ju-Hui
    • Journal of the Korean Society of Fisheries and Ocean Technology
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    • 제33권2호
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    • pp.118-131
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    • 1997
  • An opening efficiency experiment of anchovy boat seine has been carried out using a half size of the ordinary seine to reduce the size of the seine net and to improve the fishing efficiency from field operation. The intervals of towing boats were set at 100, 200 and 300m, and the towing speed, at 0.6, 0.9, and 1.2k't by possible combinations of them. The vertical openings of wing net, inside wing net, bagnet and flapper as well as the spreads of the seine net and the towing tension of the warp were measured, to find out efficient fishing gear and method of the anchovy boat seine. The results obtained are as follows : 1. The vertical opening of the inside wing net ranged from 8.7m to 12.0m at the normal current and from 7.0m to 10.0m at the counter current, and that of the wing net, from 8.4m to 19.8m at the normal current and from 4.9m to 16.3m at the counter current. The vertical opening of the wing net and inside wing net decreased as the towing speed and intervals of the boats increase, from 66% to 16% and from 32% to 18% of the normal opening, respectively. 2. The vertical opening of the fore of bag net ranged from 7.9m to 12.8m at the normal current and from 7.4m to 9.7m at the counter current, and that of the flapper, from 3.4m to 5.1m at the normal current and from 4.4m to 5.1m at the counter current, and that of the flapper, from 3.4m to 5.1m at the normal current and from 4.4m to 5.1m at the counter current. The vertical opening of the bag net was from 98% to 57% of the normal opening and the flapper showed a circular shape and it rose up to the upper layer with a slower towing speed. 3. The vertical opening of the end of the bag net ranged from 7.1m to 9.3m at the normal current and from 7.4m to 8.8m at the counter current. The end of the bag net rose up to the upper layer, This phenomenon was more apparent as the towing speed and the interval of the boats increase. 4. The towing tension of the experimental nets increased from 648kg to 2,716kg at the normal current and from 1,050kg to 6,010kg at the counter current with increasing towing speed. 5. The net depth of the anchovy seine was stable with the higher towing speed and the wider interval of the boats, but it was unstable by rising up to the upper layer with the lower towing speed and the narrower interval of towing boats.

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Current Status and Prospects of High-Power Fiber Laser Technology (Invited Paper) (고출력 광섬유 레이저 기술의 현황 및 전망)

  • Kwon, Youngchul;Park, Kyoungyoon;Lee, Dongyeul;Chang, Hanbyul;Lee, Seungjong;Vazquez-Zuniga, Luis Alonso;Lee, Yong Soo;Kim, Dong Hwan;Kim, Hyun Tae;Jeong, Yoonchan
    • Korean Journal of Optics and Photonics
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    • 제27권1호
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    • pp.1-17
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    • 2016
  • Over the past two decades, fiber-based lasers have made remarkable progress, now having reached power levels exceeding kilowatts and drawing a huge amount of attention from academy and industry as a replacement technology for bulk lasers. In this paper we review the significant factors that have led to the progress of fiber lasers, such as gain-fiber regimes based on ytterbium-doped silica, optical pumping schemes through the combination of laser diodes and double-clad fiber geometries, and tandem schemes for minimizing quantum defects. Furthermore, we discuss various power-limitation issues that are expected to incur with respect to the ultimate power scaling of fiber lasers, such as efficiency degradation, thermal hazard, and system-instability growth in fiber lasers, and various relevant methods to alleviate the aforementioned issues. This discussion includes fiber nonlinear effects, fiber damage, and modal-instability issues, which become more significant as the power level is scaled up. In addition, we also review beam-combining techniques, which are currently receiving a lot of attention as an alternative solution to the power-scaling limitation of high-power fiber lasers. In particular, we focus more on the discussion of the schematics of a spectral beam-combining system and their individual requirements. Finally, we discuss prospects for the future development of fiber laser technologies, for them to leap forward from where they are now, and to continue to advance in terms of their power scalability.

End Point Temperature of Rewarming and Afterdrop After Hypothermic Cardiopulmonary Bypass in Pediatric Patients (소아에서의 저체온 심폐바이패스후 재가온 종료온도와 후하강)

  • Kim, Won-Gon;Lee, Hae-Won;Lim, Cheong
    • Journal of Chest Surgery
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    • 제30권2호
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    • pp.125-130
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    • 1997
  • Separating the patient from hypothermic cardiopulmonary bypass(CPB) before achieving adequate rewarming often results in afterdrop, which can predispose to electrolyte disturbances, arrhythmia, hemodynamic alterations, and shivering-induced increase of oxygen consumption. In an attempt to find an adequate end point temperature of rewarming after hypothermic CPB, 50 pediatric cardiac surgical patients were r ndomly assigned for end point temperature of rewarming of 35.5$^{\circ}C$ (Group 1) or 37t (Group 2), rectal temperature. Thereafter the rectal temperature was measured half, one, four, eight, and 16 hour after arrival to the intensive care unit(ICU), with heart rate and blood pressure. Additionally the rectal temperature was compared with esophageal temperature during CPB, and axillary temperature luring stay in the ICU. Nonpulsatile perfusion with a roller pump was used in all patients and a membrane or bubble oxygenator was used for oxygenation. Both groups were comparable with respect to age, sex, body surface area, total bypass time, and rewarming time. There was no afterdrop in both groups, and there were no statistical differences in the rectal temperatures between two groups. There were also no statistical dilyerences with respect to the heart rate and blood pressure between two groups. At the end of rewarming the esophageal temperature was higher than the rectal temperature. The axil ary temperature measured in ICU was always lower than the rectal temperature. No shivering was noted in all patients. In conclusion, with restoration of rectal temperature above 35.5$^{\circ}C$ at the end of CPB in pediatric patients, we did not observe an afterdrop.

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Stability of Saturation Controllers for the Active Vibration Control of Linear Structures (선형 구조물의 능동 진동 제어를 위한 포화 제어기의 안정성)

  • Moon, Seok-Jun;Lim, Chae-Wook;Huh, Young-Chul
    • Journal of the Earthquake Engineering Society of Korea
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    • 제10권6호
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    • pp.93-102
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    • 2006
  • Control input's saturation of active control devices for large structures under large external disturbances are often occurred. It is more difficult to obtain the exact values of mass and stiffness as structures are higher. The modelling errors between mathematical models and real structures must be also included as parameter uncertainties. Therefore, in active vibration control of civil engineering structures like buildings and bridges, the robust saturation controller design method considering both control input's saturation and parameter uncertainties of system is needed. In this paper, stabilities of linear optimal controller LQR, modified bang-bang controller, saturated sliding mode controller, and robust saturation controller among various controllers which have been studied and applied to active vibration control of buildings are investigated. Especially, unstable phenomena of the LQR, the modified bang-bang controller and the saturated sliding mode controller when the control input is saturated or parameter uncertainties exist are presented to show the necessity of the robust saturation controller. The robust stability of the robust saturation controller are shown through a numerical example of a 2DOF linear vibrating system and an experimental test of the two-story structure with an active mass damper (AMD).

Performance Experiments and Analysis of Nonlinear Behavior for HDRB using in Seismic Isolation (면진용 고감쇠 적층고무베어링의 성능 특성 실험 및 비선형 거동해석)

  • Koo, Gyeong-Hoi;Lee, Jae-Han;Yoo, Bong
    • Journal of the Earthquake Engineering Society of Korea
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    • 제2권4호
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    • pp.73-86
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    • 1998
  • The purpose of this paper is to evaluate the shear stiffness, hysteretic behavior, and ultimate behavior of HDRB(High Damping Rubber Bearing), which will be included in the seismic isolation design guideline as requirements. To do this, two 1/8 scaled HDRB are designed, fabricated, and tested to show the mechanical characteristics. The shear stiffness obtained from the proposed equation of the shear stiffness shows a good agreement with those of the experiments. For analysis of the hysteretic behavior of HDRB using the modified rate model, the parameter equations are obtained from the experiments. Using the obtained parameter equations for the modified rate model, the seismic response analyses are carried out for 1-D system. The results of analysis well follow the hysteretic behavior of HDRB obtained from the experiments. To evaluate the ultimate behavior of HDRB used in this paper, the analyses are carried out using the modified macro model, which can consider the large shear deflection. The critical shear strain(CSS) is defined to express the maximum allowable shear strain and vertical load. From the analyses, the CSS, showing the instability, decreases significantly as increased the vertical loads. The CSS is not appeared for the design vertical load in the used HDRB. In analysis using about 5 times of design vertical load, the HDRB start to show the instability transient and for about 7 times, the CSS is about 350%.

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Evaluation of Downflow Granular Media Filtration for Stormwater Treatment (강우유출수에 의한 비점오염 저감을 위한 하향류식 입상여과 효율 평가)

  • Lim, Chan-Su;Kim, Do-Gun;Ko, Seok-Oh
    • Journal of Korean Society of Environmental Engineers
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    • 제34권10호
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    • pp.684-693
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    • 2012
  • The stormwater runoff from the increasing paved roads and vehicles resulted in the increase in the pollutants load to adjacent water bodies. The granular media filtration facilities are the most widely adopted to minimize the non-point source pollution from motorways. It is essential to consider the severe variation of hydraulic condition, suspended solid (SS) characteristics, and the medium characteristics for stormwater management filter. In this study, different types of media, including sand, were tested and the performance of downflow sand filters was investigated under various linear velocity and influent solid particle size. Results showed that the best medium is the coarse sand with large grain size, which showed the specific SS removal before clogging of more than $8.498kg/m^2$, the SS removal of higher than 95%, and minimum head loss. Linear velocity did not affect the total solid removal, while the performance was improved when fine solid was introduced. It is suggested that the life of a downflow sand filter bed can be extended by deep bed filtration when influent particles are fine. However, the captured particles can be washed out after a long period of operation.

In Relation to Entrepreneurial Orientation, Dynamic Capability and Export Performance of International New Ventures, the Moderating Effect of External Trade Environment (국제신벤처기업의 기업가지향성, 동적역량, 수출성과 관계와 외부 통상환경의 조절효과)

  • Cho, Yeon-Sung
    • International Commerce and Information Review
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    • 제15권3호
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    • pp.3-24
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    • 2013
  • This study has examined the relationship between entrepreneurial orientation(EO), dynamic capability(DC) and export performance of international new ventures(INVs). Also, the moderating effect of external environment factors(the hostility at domestic markets and the industrial dynamics) were analysed. Empirical analysis was performed on 101 INVs. It was conducted using the PLS(Partial Least Square). The result of empirical analysis showed that there is a positive relationship between EO, DC and export performance. The result of moderating effect showed that two external environment factors have positive moderating effect on the relationship between EO and DC. However, there was not moderating effect of external environment factors on the relationship between DC and export performance.

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Effects of Cooking Methods with Different Heat Intensities on Antioxidant Activity and Physicochemical Properties of Garlic (열처리 조리방법이 마늘의 항산화 활성과 이화학적 특성에 미치는 영향)

  • Jo, Hyeri;Surh, Jeonghee
    • Journal of the Korean Society of Food Science and Nutrition
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    • 제45권12호
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    • pp.1784-1791
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    • 2016
  • Garlic was subjected to eight different cooking methods (raw, boiling, steaming, microwave cooking, deep-frying, oven-roasting, pan-frying, and pan-roasting) utilized for typical Korean cuisine. Garlic was analyzed for antioxidant activities and physicochemical properties to elucidate effects of cooking. Garlic cooked at higher temperatures showed significantly lower lightness and higher yellowness (P<0.001). In particular, deep-frying and pan-frying resulted in lowest lightness and soluble solid content, indicating that non-enzymatic browning reactions were more facilitated. Compared with raw garlic, all cooked garlic tended to have lower thiosulfinates, presumably due to decomposition into polysulfides and/or leaching into cooking water and oil. Microwave cooking retained organic acids, total reducing capacity, and flavonoids, which can be attributed to low microwave intensity and shorter cooking time under which heat-labile bioactive components might have undergone less decomposition. Cooking significantly increased metal-chelating activity (P<0.001). In addition, oven-roasting and pan-roasting enhanced total reducing capacity and flavonoid content, indicating that thermal treatments increased the extractability of bioactive components from garlic. However, boiling, deep-frying, and pan-frying, in which garlic is in contact directly with a hot cooking medium, reduced antioxidant activities. Deep-frying resulted in largest reduction in DPPH radical scavenging activity of garlic, which correlated well with reduction of total reducing capacity and flavonoid content. The results show that the antioxidant activity of garlic could be affected by cooking method, particularly heat intensity and/or direct contact of the cooking medium.