• Proceedings of the Korea Information Processing Society Conference
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• 2019.10a
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• pp.754-757
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• 2019

대한민국 인구의 고령화는 점점 더 심화되며 노인 환자의 수도 증가하는 추세이다. 노인환자들은 의약품 부작용 위험도가 높기 때문에 노인에게 부적절한 약물과 처방 이후의 부작용 발생 현황에 대한 통계적인 분석이 필요하다고 판단하였다. 의약품 부작용관련 문헌 정보와 실제 병원의 전자 의무 기록을 이용해 데이터 베이스를 구축하고 Python 을 사용해 부작용 탐지 알고리즘을 설계했다. 노인 환자가 특정 약품을 투약한 이후에 그 약품에 부작용에 해당하는 진단을 받는다면 부작용이 발생한 것으로 판단한다. 알고리즘을 기반으로 사용자들이 쉽게 접근할 수 있도록 웹을 구축했다. d3.js 를 통해 직관적으로 부작용 확률을 확인할 수 있도록 구현했고 새로운 진단 또는 처방을 입력하여 실시간으로 확률에 반영하였다. 실시간으로 데이터를 확인할 수 있기 때문에 부작용 이슈에 신속하게 예방 및 대응이 가능할 것으로 기대된다.

• Journal of the Korean Society of Radiology
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• v.16 no.3
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• pp.357-363
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• 2022

This study aims to improve the safety inspection awareness of occupational exposure and help radiation safety management by analyzing radiation exposure doses by occupational type of radiation related-workers and radiation workers. Radiation-related workers and radiation workers were classified into three occupations (radiological technologist, doctors, and nurses). A nominal risk coefficient based on ICRP 103 was used to calculate the probability of causing side effects of the lungs due to exposure doses. As a result of analyzing the exposure dose of all workers for one year, the exposure dose of radiological technologist among radiation-related workers was 1.63 ± 2.84 mSv, doctors 0.12 ± 0.22 mSv, and nurses 0.59 ± 1.08 mSv. The one-year deep dose for radiation workers was 2.44 ± 3.30 mSv for radiological technologists, 0.19 ± 0.26 mSv for doctors, and 0.12 ± 0.00 mSv for nurses. Due to this dose, the probability of causing side effects in the lungs was 1.2 per 100,000 radiological technologist, 0.096 doctors, and 0.06 nurses. In this study, it is believed that the probability of side effects on lungs by occupation of radiation exposure dose will be studied and used as useful data for radiation safety management in relation to probabilistic effects in the future.

• Radiation Oncology Journal
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• v.15 no.3
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• pp.243-249
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• 1997

Purpose : In radiation therapy, NTCF is very importart indicator of selecting the optimal treatment plan. In our study, we tried to find out usefullness of NTCP in lung cancer by comparng the incidence of radiation pneumonitis with NTCP. Materials and Methods : From August 1993 to December 1994, thirty six patients with locally advanced non=small cell lung cancer were treated by concurrent chemoradiation therapy. Total dose of radiation therapy was 6480cGy (120cGy, bid) and chemotherapeutlc agents were mitomycin C. vinblastion, cisplatin (2 cycles, 4 weeks interval). We evaluated the development of raniation pneumonitis by CT scan, chest x-rar and clinical symptoms. We used grading system of South Western Oncology Group (SWOG) for radiation pneumanitis. Dose Volume Histograms (DVH) were analyzed for ipsilateral and whole lung, Non uniform DVH was translated to uniform DVH by effective volume method. With these data, we calculated NTCP for ipsilateral and whole lung. Finally we compared the clinical results to NTCP. Results : Eight of thrity six patients developed radiation pneumonitis. Of these 8 patients , 6 had grade I severity and 2 had grade II. The average NTCP value cf the patients who showed radiation pneumonitis was significantly higher than that uf the patients without pneumonitis $(66\%\;vs.\;26.4\%)$. But the results of pulmonary function test was not correlated with NTCP. Conclusion : NTCP of lung is very good indicator for selecting rival treatment planning in lung cancer. According to the results of NTCP, it may be possible to adjust target volume and optimize target dose. In the near future, we are going to anaiyze the effect of hyperfractionation and concurrent chemotherapy in addition to NTCP.

• Radiation Oncology Journal
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• v.28 no.1
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• pp.23-31
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• 2010

Purpose: To evaluate the relationship between the normal tissue complication probability (NTCP) of 3-dimensional (3-D) radiotherapy and the radiographic parameters of 2-dimensional (2-D) radiotherapy such as central lung distance (CLD) and maximal heart distance (MHD). Materials and Methods: We analyzed 110 patients who were treated with postoperative radiotherapy for breast cancer. A two-field tangential technique, a three-field technique, and the reverse hockey stick method were used. The radiation dose administered to whole breast or the chest wall was 50.4 Gy, whereas a 45 Gy was administered to the supraclavicular field. The NTCPs of the heart and lung were calculated by the modified Lyman model and the relative seriality model. Results: For all patients, the NTCPs of radiation-induced pneumonitis and cardiac mortality were 0.5% and 0.7%, respectively. The NTCP of radiation-induced pneumonitis was higher in patients treated with the reverse hockey stick method than in those treated by other two techniques (0.0%, 0.0%, 3.1%, p<0.001). The NTCP of radiation-induced pneumonitis increased with CLD. The NTCP of cardiac mortality increased with MHD ($R^2=0.808$). Conclusion: We found a close correlation between the NTCP of 3-D radiotherapy and 2-D radiographic parameters. Our results are useful to reanalyze the previous 2-D based clinical reports about breast radiation therapy complications as a viewpoint of NTCP.

• Journal of the Korea Society of Computer and Information
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• v.18 no.5
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• pp.147-156
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• 2013

Each field of modern society, industrialization and the development of science and technology are rapidly changing. However, as a side effect of rapid social change has caused various problems. Crime of the side effects of rapid social change is a big problem. In this paper, a model for predicting crime and Markov chains applied to the crime, predictive modeling is proposed. Markov chain modeling of the existing one with the overall status of the case determined the probability of predicting the future, but this paper predict the events to increase the probability of occurrence probability of the prediction and the recent state of the entire state was divided by the probability of the prediction. And the whole state and the probability of the prediction and the recent state by applying the average of the prediction probability and the probability of the prediction model were implemented. Data was applied to the incidence of crime. As a result, the entire state applies only when the probability of the prediction than the entire state and the last state is calculated by dividing the probability value. And that means when applied to predict the probability, close to the crime was concluded that prediction.

• Proceedings of the Korea Contents Association Conference
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• 2018.05a
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• pp.403-404
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• 2018

본 연구에서는 20대 여성의 미용성형 경험과 미용성형수술 수용성(ACS)의 관계와 영향요인을 조사하였다. 무작위 표집한 20대 여성 330명을 대상으로 2017년 11월에 자료 수집을 하였다. 수집된 자료는 서술적 통계, t-test, crosstabs, chi-square test, ANOVA, correlation, binary logistic regression으로 분석하였다. 연구결과, 97.9%는 미용성형의 부작용에 대해 들어본 경험이 있었고, 정보원으로는 인터넷이 57.3%로 가장 많았다. 124명(37.6%)은 최소 1회 이상의 미용성형 경험이 있었고, 최초 성형을 한 연령은 21.81(${\pm}2.83$)세였다. ACS는 외모만족도와 음의 상관관계(r=-0.18, p=.001)가 있었다. 미용성형 경험 여부에 영향을 미치는 요인은 연령, ACS와 BMI였고, 변수들의 설명력은 28.9%였다. 연령이 1살이 높아질수록 미용성형 경험이 있을 확률이 1.17배 높아지고(OR=1.17, p=.002), ACS가 1점이 높아질수록 미용성형 경험이 있을 확률이 1.06배 높았으며(OR=1.06, p<.001), BMI 점수가 1점이 높아질수록 미용성형의 경험이 있을 확률이 0.84배 낮아졌다(OR=0.84, p<.001). 대상자의 심신건강을 위한 관련 정책을 위하여 점차 증가하는 20대 여성의 미용성형수술과 관련한 다양한 영향요인을 조사 등 후속연구를 제언한다.

• Journal of the Korean Society of Radiology
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• v.17 no.3
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• pp.473-479
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• 2023

In this study, the dose of photoneutrons generated during radiotherapy of prostate cancer using high energy was measured using a photo-stimulated luminescence dosimeter. In addition, this study was intended to study the probability of side effects occurring in the abdomen. A medical linear accelerator capable of generating 15 MV energy, True Beam STx (Varian Medical Systems, USA) and a radiation treatment planning system (Eclipse, Varian Medical Systems, USA) were used. A human body phantom was installed on the couch of the linear accelerator, and an Albedo Neutron Optical Stimulation Luminescence Neutron Detector (Landauer Inc., IL, USA) was used to measure the photoneutron dose. The photoneutron dose value in the abdomen of VMAT and 3C-CRT was 52.8 mSv, more than twice as high as VMAT compared to 3D-CRT. During radiotherapy of prostate cancer, the probability of causing side effects in the abdomen due to light neutron dose was calculated to be 3.2 per 1,000 for VMAT and 1.4 for 3D-CRT. By studying the abdomen, which has a major side effect that can occur during radiotherapy of prostate cancer, it is expected that it will be used as a meaningful study to study the quality of life and stochastic effect of prostate cancer patients

• Journal of the Korean Society of Radiology
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• v.17 no.3
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• pp.481-487
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• 2023

In this study, we analyzed the incidence of side effects of photoneutron dose according to the number of beams during intensity-modulated radiotherapy of prostate cancer using 15 MV. The radiation treatment plan design for intensity-modulated radiation therapy for prostate cancer was established with a prescription dose of 220 cGy per dose and a total of 7260 cGy for 33 treatments. The linear accelerator used in the experiment is Varian's True Beam STx (Varian, USA). Photoneutron dose was generated by using 15 MV energy in the planning target volume (PTV). The treatment plan was designed with IMRT 5, 7, and 9 portals using the Eclipse System (Varian Ver 10.0, USA). An optically stimulated luminescence albedo neutron dosimeter (Landauer Inc., USA) was used to measure photoneutron dose. IMRT 5 portals, 1.7 per 1,000, 7 portals, 1.8 per 1,000, 9 portals, 2.0 per 1,000 were calculated as the probability of experiencing side effects on the thyroid gland due to photoneutron dose. This study studies the risk of secondary radiation exposure dose that can occur during intensity-modulated radiation therapy, and it is considered that it will be used as useful data in relation to stochastic effects in the future.

• Proceedings of the Korean Information Science Society Conference
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• 2004.10a
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• pp.304-306
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• 2004

최근 몇 년간 일어난 전산 네트워크의 폭발적인 확산은 전산 시스템에 대한 침입과 피해 또한 증가하는 부작용을 낳았다. 그에 따른 대책 방안으로 침입 탐지 시스템에 대한 관심과 연구가 증가하고 있다. 본 논문에서는 네트워크 상에서 이동하는 정보를 수집하여 HMM으로 모델링한 후, 외부 또는 내부 네트워크에서의 비정상적인 행위를 탐지하는 침입 탐지 시스템을 제안한다. 전처리를 거친 네트워크 패킷 시퀀스들은 forward-backward 절차와 Baum-Welch 재평가식을 이용하여 정상행위로 모델링 된다. 이렇게 구축된 모델을 사용하여 forward 절차를 통해 판정하려는 시퀀스가 정상 행위에서 생성되었을 확률을 계산하며 이 값을 임계값과 비교하여 정상행위 여부를 판별한다. 실험 결과 제안한 침입 탐지시스템이 다양한 침입을 적절히 탐지하는 것을 확인할 수 있었다

• Journal of the Korean Society of Radiology
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• v.17 no.2
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• pp.249-255
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• 2023

In this study, radiation exposure doses were measured in the course of clinical practice of radiation workers, radiological technologists in the radiation-related worker group, and preliminary-radiological technologists who were classified as frequent visitors. Radiological technologists who worked in the radiation area of C University Hospital in Incheon for a year from January 2021 and 121 students who completed clinical practice at the same medical institution from July 1 to August 31 were the subjects of the study. The nominal risk factor based on ICRP 103 was used to evaluate the probability of side effects due to the exposure dose to the lungs, which are organs at risk of damage due to radiation exposure dose. During the clinical practice period, radiology students, who were classified as frequent visitors, had a surface dose of 0.98 ± 0.14 mSv and a deep dose of 0.93 ± 0.14 mSv. In other words, 6.7 per 1,000,000 for shallow dose and 6.4 per 1,000,000 for deep dose were found to have side effects due to exposure to the lungs. This is a value in terms of exposure dose in one year. Considering that the radiation (science) education course is 3 or 4 years, systematic management and attention to prospective radiation workers who are going to clinical practice are required, and the stochastic effect of radiation In relation to this, it is considered that it will be used as basic data for radiation safety management.