• 대한한방부인과학회지
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• 제35권2호
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• pp.1-15
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• 2022

Objectives: The purpose of this study is to report the results of Korean medicine treatment infertility support program in Gwang-ju Metropolitan City in 2021. Methods: Participants of Korean medicine treatment infertility support program were provided Herbal medicine, acupuncture, pharmacopuncture and Counseling for 3 months and followed up for 3 months after the treatments. The project was carried out for 100 infertile women under the age of 42 living in Gwang-ju Metropolitan City, of which 91 completed treatment until the end. Collected data of 91 women containing pregnancy rates, characteristics of subjects, treatments, and satisfaction of the program were analyzed. Results: After the treatment, 23 out of 91 subjects were pregnant, two of whom were miscarried, and 21 were maintained. The average age of pregnant women in 23 pregnant subjects was 33.8 years old, of which the average age of those who maintained pregnancy was 32.4 years old, and the age of one miscarried person was 39 years old. More than 85% of subjects answered that they were satisfied with the program in the satisfaction survey. Conclusions: Based on this report, the clinical data were obtained from the infertility treatment program. This study can be used as basic data to help establish infertility support programs and subsequent policies like support for men in the future Korean medicine infertility project and extension of the herbal medicine treatment period.

• 대한한방부인과학회지
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• 제36권3호
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• pp.25-45
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• 2023

Objectives: The purpose of this study is to review the clinical research trends of ovarian cysts and to recognize the efficacy of Korean medicine intervention. Methods: Based on four domestic databases, including Korean studies Information Service System (KISS), Oriental Medicine Advanced Searching Integrated System (OASIS), Korean Medical Database (KMbase) and Research Information Sharing Service (RISS), we analyzed the case reports using Korean medicine intervention, which include acupuncture, moxibustion and herbal medicine. Data retrieval was carried out from May 12^th, to 18^th, 2022, and a total of 9 papers were included. Results: All papers were published in Korea and they contain seventeen case reports in total. The most frequently used intervention was herbal medicine, especially Gyejibokryeong-hwan-gami (桂枝茯苓丸加味), Guichulpajing-tang-gagam (歸朮破癥湯加減), Guibiondam-tang-gami (歸脾溫膽湯加味). Most cases reported statistically significant results on using Korean-medicine intervention. Also, there was no serious side effect of Korean medicine. Conclusions: In this study, we investigated the efficacy of Korean medicine intervention as an adjuvant therapy for ovarian cyst patients and research trends on ovarian cysts. Further studies are needed to supplement the safety and the evaluation of Korean medicine. However, the results should be taken cautiously as more clinical studies are needed.

• 대한한방부인과학회지
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• 제36권3호
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• pp.46-61
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• 2023

Objectives: The purpose of this systemic review is to overview and evaluate the efficacy of acupuncture in female patients with chronic constipation. Methods: We conducted a comprehensive search of the literature to identify randomized controlled trials that investigated the effects of acupuncture on female patients with chronic constipation. Key words searched included "Female Constipation", "Women Constipation", "Acupuncture" in database KISS, DBPIA, RISS, Cochrane Central, Scopus, Pubmed, CNKI. Results: Nine randomized controlled trials met our inclusion criteria and were included in this systematic review. Our analysis found that acupuncture was associated with significant improvements in spontaneous bowel movements, complete spontaneous bowel movements, stool consistency, and quality of life in female patients with chronic constipation. Acupuncture was generally well-tolerated, with few adverse effects reported. Conclusions: Our findings suggest that acupuncture treatment would be effective way to treat chronic constipation of female patients.

• 대한한방부인과학회지
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• 제22권4호
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• pp.65-82
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• 2009

Purpose: The purpose of this study is to examine acupuncture intervention suggested in the papers of assisted reproductive technology(ART, hereafter) in medicine journals and to establish the further direction. Methods: The papers published between 1996 and 2009 in Pubmed were reviewed. Results: 1. A variety of randomized controlled trials and case series were found in Pubmed concerning influence of acupuncture in ART. It was investigated into improvement of pregnancy rate, analgesic effect during oocyte retrieval, change of serum hormone, and reduction of anxiety. 2. It was on clinical pregnancy rate that main focus of the investigation was placed and the improvement of pregnancy rate differed from studies. 3. For the analgesic effect during oocyte retrieval, the electro acupuncture was mainly used and the studies reported the reduced pain rate, tiredness, and nausea. 4. Acupuncture was reported as significant in improving the state of anxiety during ART. Conclusion: It would be necessary to further study the period of acupuncture intervention, the selection of acupoint through well-designed study, and establish standard of evidence of them.

• 대한한방부인과학회지
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• 제22권2호
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• pp.172-188
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• 2009

Purpose: For mothers just delivered of a child, sanhupung(産後風) is a critical disease which can threaten their health. The symptoms of sanhupung were diverse and divided into pain symptoms, general symptoms, and neuropsychiatric symptoms. We tried to search for the relationship between sanhupung and somatization of postpartum depression. Methods: Analysis was carried out with materials concerning the postpartum depression and sanhupung. For the analysis, materials related with the issue of this study were searched at the Korea Education & Research Information Service, and Oriental medicine advanced searching. Results: 1. The range of period and symptoms of sanhupung has been broaden. The symptoms of sanhupung were divided into pain syndrome, general symptoms, and neuropsychiatric symptoms. 2. As the symptoms of postpartum depression might indicate not only physical symptoms but also mental disorder, more attention should be placed on wether the symptoms were involved in somatization of postpartum depression. Conclusion: The authors conclude that obstinate sanhupung that do not healed up and improve in symptoms have a relation to somatization of postpartum depression.

• 대한한방부인과학회지
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• 제22권2호
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• pp.94-118
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• 2009

Purpose: Gleditsiae spina (GS) has been used to treat patients with several diseases such as carbuncle, swelling and parasites. Recently GS is known to have anticancer activity in abdominal solid tumor, but the effects of GS on breast cancers is not clarified. For these reasons, we investigated effects of Gleditsiae spina (GS) on gene expression of human breast cancer cells. Methods: We investigated the effects of GS on proliferation of breast cancer cell line, MDA-MB-231. In addition, the genetic profile for the effect of GS on breast cancer cells was measured using microarray technique, and the functional analysis on these genes was conducted. Results: Total 1,434 genes were up-regulated and 2,483 genes down-regulated in the cells treated with GS. Genes induced or suppressed by GS were all mainly concerned with metabolic process, regulation of biological process and protein binding. The network of total protein interactions was measured using cytoscape program, and some key molecules that can be used for elucidation of therapeutical mechanism of medicine in future were identified. Conclusion: These results suggest possibility of GS as anti-cancer drug for breast cancer, and also suggest that related mechanisms are involved in regulation of intra-cellular metabolism in breast cancer cells.

• 대한한방부인과학회지
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• 제22권3호
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• pp.152-168
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• 2009

Purpose: The purpose of this study is to examine remedies suggested in the papers of ovarian cyst in Chinese Medicine Journals and to establish the further direction. Methods: The papers published between 1994 and 2009 in China Academic Journal were reviewed. Results: 1. It was on Bo-Ryu Enema that main focus of investigation was placed. A variety of randomized controlled trials and case series were found. As a result, a lot of proper manual arts and prescriptions were provided out of them. 2. Acupuncture is reported as significant in reducing the size of ovarian cyst and improving clinical symptoms, which covers electrical acupuncture, enlongated needle and moxibustion, burning acupuncture. 3. External application was verified as an effective therapy for the case of a combined treatment with oral medicine. 4. Modern medical equipments such as ultra short wave medical cure, TDP could improve the efficiency of traditional remedies like Bo-Ryu Enema, external application. Conclusion: It would be necessary to practically come up with a diversity of remedies besides oral decoction of medical ingredients, and establish standard of evidence of them.

• 대한한방부인과학회지
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• 제22권1호
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• pp.95-109
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• 2009

Purpose: This study was performed to determine the inhibitory effect of Sihosogansangagambang (SS) on melanin synthesis in B16F10 melanoma cells (B16F10). Methods: The inhibitory effects of Sihosogansangagambang on melanin synthesis were used by in vitro assay. To elucidate inhibitory effects of SS on melanin synthesis, we determined the melanin release in B16F10. And to investigate the mechanism of inhibitory effect of SS, we assessed the gene expression of tyrosinase, TRP-1, TRP-2 and ERK-1 in B16F10. Results: 1. SS decreased the release of melanin in B16F10 melanoma cells. 2. SS inhibited mushroom tyrosinase activity in vitro. 3. SS decreased the expression of tyrosinase, TRP-2 in B16F10 melanoma cells, but did not decreased the expression of TRP-1 in B16F10 melanoma cells. 4. SS decreased the expression of ERK-1 in B16F10 melanoma cells. Conclusion: From these results, it may be suggested that SS is possesed of the antimelanogenetic effects.

• 대한한방부인과학회지
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• 제22권3호
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• pp.257-266
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• 2009

Purpose: The purpose of this study is to report the clinical effectiveness of Traditional Korean therapy on coccygodynia and depression of postpartum. Methods : The patient in this case was 27-year-old female. The chief complains were coccygodynia and depression. She was treated by Traditional Korean medicine, acupuncture and Chuna Manipulation. The progress of symptoms was evaluated by visual analogue scale(VAS) and Oswestry Disability Index(ODI). Results : After those Traditional Korean therapy, most symptoms were improved. Coccygodynia and uncomfortableness in normal life improved, and ODI was decreased from 35 to 17. Conclusion : This case shows that Traditional Korean therapy might be effective in decreasing symptoms on coccygodynia and depression of postpartum.

• 대한한의학원전학회지
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• 제18권1호통권28호
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• pp.81-93
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• 2005

통과대명청시대부과치료법급방제적연구(通過對明淸時代婦科治療法及方劑的硏究), 득출여하결논(得出如下結論): 수송대대부과질병중시기혈병기적영향(受宋代對婦科疾病重視氣血病機的影響), 명청시대수연이조기(明淸時代雖然以調氣), 보허(補虛), 양혈(凉血), 청열(淸熱), 작위조경적사대강요이강조조기(作爲調經的四大綱要而强調調氣), 단역주장필수요변증논치(但亦主張必須要辨證論治). 명청시대적태전조치법(但亦主張必須要辨證論治), 시수주진형적산전요청열양혈리논적영향이발전기내적(是受朱震亨的産前要淸熱養血理論的影響而發展起來的). 우기시발생소(尤其是發生小) 산후(産後), 왕륜주장하차임신시(王綸主張下次妊娠時), 수사전복약이예방발생타태(需事前服藥以豫防發生墮胎). 이차독특적견해(以此獨特的見解), 용내예방타태(用來豫防墮胎). ${\ulcorner}$연수신방(延壽神方)${\lrcorner}$중기재적일종산후조치법(中記載的一種産後調治法), 시류사실내공기급산부호흡도적초훈소독법(是類似室內空氣及産婦呼吸道的醋熏消毒法). 차방법대산부호흡도감염적발생(此方法對産婦呼吸道感染的發生), 구유예방작용(具有豫防作用).