• Radiation Oncology Journal
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• v.14 no.2
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• pp.149-158
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• 1996

Purpose : To get an accute steepness of dose gradients at outside the target volume in intracranial lesion and a less limitation of beam selection avoiding the high dose at normal brain tissue, this Photon Knife Radiosurgery System was developed in order to provide the three-dimensional dose distribution through the reconstruction of CT scan and the combined stereotactic trans-multiarc beam mode based on linear accelerator photon beam. Materials and methods : This stereotactic radiosurgery, Photon Knife based on linear accelerator photon beam was provided the non-coplanar multiarc and trans-multiarc irradiations. The stereotactic trans-multiarc beam mode can be obtained from the patient position in decubitus. This study has provided the 3-dimensional isodose curve and anatomical structures with the surface rendering technique. The dose distribution from the combined two trans-multiarcs (2M 2TM) was compared to that of four non-coplanar multiarcs (4M) with same collimator size of 25 mm in a diameter and total gantry movements. Results : In this study, it shows that the dose distributions of stereotactic beam mode are significantly depended on the selected couch and gantry angle in same collimator size. Practical dose distribution of combined stereotactic trans-multiarc beam has shown a more small rim thickness than that of the non-coplanar multiarc beam mode in axial, sagittal and coronal plane in our study. 3-Dimensional dose line displayed with surface rendering of irregular target shape is helpful to determine the target dose and to predict the prognosis in follow-up radiosurgery. Conclusions : 3-Dimensional dose line displayed with surface rendering of irregular target shape is essential in stereotactic radiosurgery. This combined stereotactic trans-multiarc beam has shown a less limitation of the selection couch and gantry beam angles for the target surrounding critical organs. It has shown that the dose distribution of combined trans-multiarc beam greatly depended on the couch and gantry angles. In our experiments, the absorbed dose has been decreased to $27%$ / mm in maximum at the interval of $50\%$ to $80\%$ of isodose line.

• Proceedings of the Korean DIstribution Association Conference
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• 2003.02a
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• pp.169-200
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• 2003

소비자의 욕구변화와 정보기술의 발전으로 정보경제시대, 신경제시대가 도래함에 따라 가치사슬이 변화하고, 새로운 가치를 창출하는 신산업이 등장하고 있다. 인터넷의 확산과 더불어 선으로부터의 자유, 개인성, 즉시성이 가능한 모바일 비즈니스가 우리나라에서도 태동하고 있다. 모바일 비즈니스는 금융업체, 정보제공업체, 통신망 운용업체, 최종이용자간의 새로운 가치의 결합이 특징이며, 막 흐름이 만들어지고 발전되고 있는 상황이다. 이와 같이 다양한 이해관계자가개입하고 있어 협력이 특히 강조되고 또 요구되고 있다. 이러한 중요성에도 불구하고 이들간의 관계에 대한 연구가 미흡한 편이다. 따라서 본 연구는 모바일 비즈니스를 주도하고 있는 통신망 제공업체와 모바일 컨텐츠 공급 파트너간의 조직간 협력관계에 대한 실증 연구를 수행하였다. 관계마케팅, 거래비용, 자원기반관점, 네트워크 이론 등 기업간 관계를 기술, 설명, 예측하는 주요이론에서 논의되고 있는 개념을 바탕으로 본 연구는 컨텐츠 공급파트너의 전략적 성과에 영향을 주는 연구 모형을 제시한다. 최근 중요성이 더 강조되고 있는 항목은 신뢰와 결속임을 감안하여, 매개변수로써 전략적 성과에 영향을 주는 주요한 요소로 신뢰와 결속을 제시하고 있다. 컨텐츠 제공업체의 전략적 성과는 서비스제공업체에 대한 신뢰와 결속에 큰 영향을 받고있다는 점을 반영하고 있다. 한편 신뢰에 영향을 주는 독립변수로는 서비스 제공업체에 대한 평판, 서비스제공업체와 컨텐츠 제공 파트너간의 상호의사소통, 그리고 업무처리의 절차에 대한 공정성을 제시하고 있다 결속에 영향을 미치는 독립변수로는 동의된 목표, 업무정보교류, 거래특유자산의 3개의 변수를 선정하였다. 독립, 매개, 종속변수간의 9개의 연구 가설을 수립하였다. 국내의 주도적인 이동통신망소유업체에 모바일 컨텐츠를 공급하고 있는 170여개의 파트너를 대상으로 실증연구를 수행했다. 공변량 구조분석을 위주로 분석한 연구의 결과에 의하면 본 연구의 모델은 충분한 적합성을 보여주고 있는 것으로 나타났다. 또한 가설의 상당수가 채택이 되었다. 그러나 모바일 비즈니스의 기업간관계의 실제측면을 나타내는 업무정보교류와 결속자의 관계의 유의하지 않게 나와 기각되었다. 기각에 대한 여러 가지의 해석이 가능하지만 측정의 신뢰성을 확보해야 하고 개념의 타당성을 더 엄격하게 준수할 필요성이 제기되었다. 본 연구는 조직이론에 근거한 변수를 채택하고 있으나 모바일 비즈니스의 생명주기특성상 태동기이기 때문에 기업간 관계를 연구하는 측면에서는 탐험적 연구성격이 강하다. 더 나아가 본 산업의 주된 연구가 질적이고 기업내부만을 연구했던 것에 비교하면 시초적이라고 할 수 있다. 또한 관계마케팅, CRM 등의 이론적 배경이 되고 있는 신뢰와 결속의 중요성이 재확인하는 결과도 의의라고 할 수 있다. 그리고 신뢰는 양사 간의 상호관계에서 조성될 수 있는 특성을 가진 반면, 결속은 계약관계 초기단계에서 성문화하고 규정화 할 수 있는 변수의 성격이 강하다고 할 수가 있다. 본 연구는 복잡한 기업간 관계를 지나치게 협력적 측면에서만 규명했기 때문에 많은 측면을 간과할 가능성이 있다. 또한 방법론적으로 일방향의 시각만을 고려했고, 횡단적 조사를 통하고 국내의 한 서비스제공업체와 관련이 있는 컨텐츠 공급파트너만의 시각을 검증했기 때문에 해석에서 유의할 필요가 있다. 또한 타당성확보 노력을 기하였지만 측정도구 면에서 엄격한 개발과정을 준수하지는 못했다. 향후에는 모바일 컨텐츠 파트너의 기업의 특성을 조사하여 관계성 변수와의 상호관련연구를 진행할 필요가 있다. 관계기간, 의존성, 거래처의 단/복수여부, 서비스 범주 등의 제반 변수를 고려하여 이러한 변수가 양사와의 관계성 변수에 어떤 영향이 있는가를 검증할 필요가 있다. 또한 신뢰, 결속 등 다차원의 개념에 대한 심도 깊은 연구와 최근 제기되고 있는 이론의 확대도 필요하다. 마지막으로 신뢰와 결속에 영향을 미치는 요소간의 개념적 분류, 차이의 검증, 영향력 등을 광범위하게 진행시킬 필요가 있다.

• Journal of Life Science
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• v.19 no.12
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• pp.1847-1850
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• 2009

Bovine tuberculosis is generally detected postmortem because it is a chronic debilitating disease. Since tuberculosis is mainly found in the lungs, clinical signs including coughing, nasal discharge, and difficulty breathing can occur in severe instances. In the present study, specimens were collected from the heart, liver, kidney, lung, pleural cavities, lymph nodes and intestines of carcasses found in an abattoir. According to post-mortem examination and inspection of carcasses, tuberculosis lesions were varied in appearance and size. Tubercles of a white cream color were disseminated throughout the pleural cavity including the lymph nodes, lungs and mesentery containing pus. Gram and Ziehl-Neelsen's acid-fast staining for the lung and lymph nodes revealed a highly positive histochemical reaction. The acid-fast organisms were observed histologically in the lesions under a microscope. This report demonstrated the histopathology of bovine tuberculosis based on the histological findings of Mycobacterium bovis, which is a suspected causative agent.

• Journal of fish pathology
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• v.22 no.3
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• pp.263-273
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• 2009

There is an increasing number of reports describing Streptococcus parauberis as an important pathogen of cultured olive flounder Paralichthys olivaceus and starry flounder Platichthys stellatus in Korea. We tried to determine the effects of water temperature (14${^{\circ}C}$ and 21${^{\circ}C}$) on the pathogenicity in Streptococcal disease caused by S. parauberis. We have challenged 180 olive flounder by i.p injection to $2.0{\times}10^{7}$ live cells/fish. Mortality was monitored for 21 days post challenge. And histopathological characterizations as infection degree, tissue degeneration and/or bacterial distribution were investigated with H&E stain and in situ hybridization technique. Fifty percent and 16.7% of mortality occurred within 21 days at 21${^{\circ}C}$ and 14${^{\circ}C}$ water temperature, respectively. In most cases, the typical symptoms of olive flounder infected with S. parauberis were darkness of the skin, lethargy, mild abdominal distension cause by ascites, splenomegaly, congested liver and internal organs paleness. The pericardial sac contained large amounts of cloudy fluid. Numerous whitish nodules, which were variable in size and often confluent, were randomly scattered throughout the myocardium. Especially, pericarditis and/or myocarditis was observed in all tested fishes after death. Positive in reaction with S. parauberis were found in all tissues in situ hybridization analysis. The relative numbers of S. parauberis in heart were much more than in liver, spleen, kidney and stomach. We evaluated that S. parauberis strain causes serious damage in the pericardium, shortness of breath and the blood disorder. Therefore, pericarditis and myocarditis caused by S. parauberis were closely related to mortality of olive flounder.

• Pediatric Gastroenterology, Hepatology & Nutrition
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• v.9 no.2
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• pp.193-199
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• 2006

Purpose: The proper diagnosis of Meckel's diverticulum (MD) is difficult and delayed because of the variety of clinical manifestations. We reviewed clinical characteristics of symptomatic MD to facilitate early detection. Methods: We analyzed retrospectively the clinical manifestations, diagnostic tools, histopathological findings, and operative findings in 58 patients with symptomatic MD. Results: The male to female ratio was 2.8 : 1. The most common symptom of MD was bleeding. Others symptoms included: vomiting, abdominal pain, irritability, abdominal distension and fever in the order of frequency. The clinical manifestations of symptomatic MD were lower gastrointestinal bleeding, intestinal obstruction, perforation, diverticulitis and hemoperitoneum, in the order of frequency. The causes of intestinal obstruction were intussusception, internal hernia, band, volvulus, invagination, in the order of frequency. Seventy five percent of patient with MD were diagnosed prior to 5 years of age. The most frequently used diagnostic tool was the Meckel's scan. The diverticulum was located 2 cm to 120 cm proximal to the ileocecal valve. The length of the diverticulum ranged from 1 cm to 10 cm and 94% were less than 5 cm. The most common ectopic tissue found in the MD was gastric mucosa. Ileal resection was more frequently performed than diverticulectomy. Conclusion: In cases of unexplained gastrointestinal bleeding, obstruction and repeated intussusception, the meckel's scan, ultrasound and computed tomography shoud be considered to rule out MD, and if clinically necessary, an exploratory laparotomy when needed.

• Journal of Korean Historical Folklife
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• no.44
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• pp.145-176
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• 2014

This study analyzed official duties and personnel practices of Hyangcheong(鄕廳), administrative organization in which sajok(士族) participate this office, and Jakcheong(作廳), hyangree(鄕吏)'s office, of Anbyeon of Hamgyeong Province in the 19th century. Although there have beeen somewhat of case study of Gyeongsang, Honam, etc., study on Hamgyeong Province has been almost nonexistent because of the limitation of materials. Hence, this paper specifically examined Hyangcheong and Jakcheong's official duties and personnel practices through an article of 'a list of Hyangcheong and Jakcheong's officials' of Anbyeon, newly found, which is in the possession of this writer. Especially, this study virtually traced individual ststus and family by analyzing Hyangcheong and Jakcheong's 40-official duties and a list of 330-ofiicial duties for sixs years. And then by comparing it against Jokbo(族譜), I have grasped 19-Famlily of them. Executives of Hyangcheong could be grasped as they were status of Yangban(兩班), but members of Jakcheong were hardly identified because they were status of hyangree, thus most of them were not enscrolled in Jokbo. Hyangcheong and Jakcheong's official duties could be found by compare it with other area in Ehubgi(邑誌) Hamgyeong Province. the features of officiak duties are as in the following. On general administrative organization, Sajok's Hayngcheong, Jakcheong as general administrative organization and Jangcheong(將廳) as police work existed. As Pyeongando and Hamgyeongdo were border areas, Jangcheong was independent and led other institutions. However, in Anbyeon, Hojang(戶長) of Hayngcheong and Jakcheong divided dudies and commanded. Hojang'role was higher than any other areas, Because Hojang is in charge of Jangcheong's functions. Jakcheong was centrally operated by Hojang, Eebang(吏房), and Hyeongbang(刑房), so-called 'Samgonghyeong(三公兄)', Whereas Anbyeon was operated by Hojang, Eebang, Chunchong(千摠). In the general areas, While Juasu(座首) Byeolgam(別監), Executive of Hyangcheong, manages each warehouse(倉) where the nation's tax revenues are kept, In Anbyeon besides Joasu, Hyangso(鄕所). The principle of Hyangcheong and Jakcheong's personnel practices was one-period, but there were many consecutive terms, every other year terms, or tranference into other area. Police work was assumed by specific persons because it was relatively specialized job, However in case of Ghamsaek(監色) of each warehouse(倉), Hyangso(鄕所) of Hyangcheong or Hojang of Jakcheong had held plural offices, and was solely responsible it. On the overall features of its operation, Hyangcheong held plural offices, but rotation was made only within Hyangcheong. On the other hand, in the case of Jakcheong, Hojang, Eebang, and even Buriebang circulated their positions, but the other Hyangree rotated each Saek(色) and Guamguan of each warehouse(倉). This writer confirmed that unlike Gyeongsang and Hamgyeong, Hyangcheoung or duties of Hyangree were not handed from generation to generation by several families and, many families shared their work by circulating positions.

• Herbal Formula Science
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• v.6 no.1
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• pp.119-139
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• 1998

This study was to investigate the protective and effects of Ikgukwhan and Ikgukbowhawhan on the liver cirrhosis or fibrosis induced by prolonged bile duct ligation; a new experimental model for cirrhosis and the intraperitoneal injection of dimethylnitrosamine in the rat. The development of fibrosis or cirrhosis and its inhibition by the two prescriptions were examined by the chemical analysis of AST, ALT, and hydroxyproline. The results obtained were as follows. 1. The increase of serum asparate aminotransferase induced by bile ductligation was inhibited by the administration of Ikgukwhan and Ikgukbowhawn extract. 2. The increase of serum alanine aminotransferase induced by bile duct ligation was inhibited by the administration of Ikgukwhan and Ikgukbowhawhan extract. 3. The increase level of serum AST and ALT induced by the intraperitoneal injection of dimethylnitrosamine was inhibited by the administration of Ikgukwhan and Ikgukbowhawhan extract. 4. The increase level of hydroxyproline volume in the damaged liver tissues in the rat was decreased by the oral administration of Ikgukwhan and Ikgukbowhawhan extract. But there were no significant differences in the inhibition rate between the two experimental groups.

• Proceedings of the Korean Operations and Management Science Society Conference
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• 2003.11a
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• pp.205-208
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• 2003

대학이 신입생을 선발하는 기준은 해당전공을 공부하는데 적합한 지원자를 선발하는 것이며, 해당모집단위에 많이 지원하게 하여 신입생 충원을 용이하게 하는 것 등이다. 대학은 입학전형을 거쳐서 신입생을 선발하게 되며, 선발기준으로 전형요소를 활용하게 된다. 전형요소 활용방법은 신입생 선발에 영향을 주기 때문에 전략적으로 중요하다. 2005학년도 신입생 선발에는 고등학교 7차 교육과정을 이수한 지원자들이 지원하게 되므로 전형요소에 있어서 변화가 있다. 대학입학수학능력 시험의 체제는 수험생들이 영역이나 과목을 선택하여 응시하는 방향으로 변화한다. 즉, 수리 영역을 가형 및 나형으로 응시하고, 하나의 탐구영역을 응시하되 사회탐구영역 및 과학탐구영역은 4과목 이내에서 선택하여 응시한다. 또한 수학능력시험의 성적표는 각 영역별 및 과목별 표준점수, 백분위점수 및 등급을 표시하여 통지한다. 본 연구는 변화된 수학능력시험의 체제와 고등학교 교육과정을 어떠한 방법으로 반영하여 학생을 선발하는 것이 바람직한가에 대한 전략을 도출하는 틀을 제시하고, 각 전형요소 활용의 대안과 문제점을 도출하고자 한다. 2005 수능시험 결과는 표준점수로 통지하기 때문에 만점 개념을 적용하기 어렵고, 표준점수를 전형요소로 활용할 때 전형총점 개념을 도입하기 어렵다. 또한 복수영역 및 과목의 선택에서 유리함과 불리함이 나타나게 된다. 과거의 수능시험결과를 분석하여 전형총점개념 도입의 방법과 불리함을 보정하여 주는 방법을 제시하고, 신입생을 선발하는 목적에 적합한 전형요소 결정전략을 도출하고자 한다.2; Learning Decisions, 2001) 연구모형을 설정하고 이를 근거로 실증연구를 수행 중에 있다.7.2 $e^{0.101}$x/, y = 70.01 $e^{0.030}$x/, 반감기는 12.0, 6.86, 23.0 일이고 폐장, 간장, 신장의 회복기간(x)별 크롬농도(y)의 소실속도 상관계수 (노출농도 0.50 mg/㎥군의 경우)는 y = 1808 $e^{0.004}$93x/, y = 12.02 $e^{0.029}$7x/, y = 67.61 $e^{0.029}$2x/ 반감기는 140.6, 23.3, 23.7 일로 평가되었다. 4. 고찰 : 실험동물의 전혈, 혈청, 뇨에서의 크롬농도와 시험물질 노출농도는 밀접한 상관을 가졌으나 농도에 정비례하지는 않았다. 뇨 중 흡수된 크롬의 경우 회복기간 초기 (12시간 내)에 대부분 배설이 일어나는 것으로 나타났다. 폐장이 간장, 신장 등 다른 장기에 비해 높은 축적량을 보였으며 축적된 크롬농도가 높을수록 크롬의 소실속도는 현저히 저하하는 경향을 보였다. 노출농도가 높을수록 각 장기조직 내 크롬의 소실속도 (clearance)는 크게 감소경향이 있었으며 이는 체내 과부하시 자정작용이 감소하는 것으로 판단되었다. 본 연구 결과 SD rat를 이용 반복흡입노출의 경우 생체의 무유해영향농도 (NOAEL)는 0.2mg/㎥이하이며 발암물질을 감안하여 안전계수를 100으로 할 경우 사람에 대한 NOAEL은 0.002mg/㎥이하로 판단되

• The Journal of the Korea Contents Association
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• v.12 no.4
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• pp.358-366
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• 2012

Cirrhosis is a consequence of chronic liver disease characterized by replacement of liver tissue by fibrosis, scar tissue and regenerative nodules leading to loss of liver function. Liver Cirrhosis is most commonly caused by alcoholism, hepatitis B and C, and fatty liver disease, but has many other possible causes. Some cases are idiopathic disease from unknown cause. Abdomen of liver Computed tomography(CT) is one of the primary imaging procedures for evaluating liver disease such as liver cirrhosis, Alcoholic liver disease(ALD), cancer, and interval changes because it is economical and easy to use. The purpose of this study is to detect technique for computer-aided diagnosis(CAD) to identify liver cirrhosis in abdomen CT. We experimented on the principal components analysis(PCA) algorithm in the other method and suggested texture information analysis(TIA). Forty clinical cases involving a total of 634 CT sectional images were used in this study. Liver cirrhosis was detected by PCA method(detection rate of 35%), and by TIA methods(detection rate of 100%-AGI, TM, MU, EN). Our present results show that our method can be regarded as a technique for CAD systems to detect liver cirrhosis in CT liver images.

• Journal of KIISE:Computer Systems and Theory
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• v.35 no.9_10
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• pp.452-465
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• 2008

This paper proposes a light-weight, seamless integrated access control for global e-Science resource sharing. E-Science, based on Grid Computing, was designed to help scientists to remotely control and process the Grid resources such as high-end equipments and remote machines. As many researchers engage in the e-Science Grids, the researchers in a grid often have to wait for or give up use of the Grid resources, even when there are idle resources in other Grids. In this case, provided that proper compensation is given, Grid resource sharing is helpful both for the researchers and the Grids which provide their resources. But, sharing Grid resources globally is not simple, as each e-Science Grid is especially designed for resource sharing in its Virtual Organization(VO) and already has its unique access control policy for its resources. This paper proposes a new integrated access control for e-Science Grid resource sharing. The access control is light-weight without any priori service level agreement(SLA)s among the Grids which share their resources and seamless because the users can use the resources shared as the ones belonging to their Grids without their additional registration to the other Grids.