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Biomarker Extraction Algorithm for Oriental Genetic Lesion (한의학적 유전병변 바이오 마커 추출 알고리즘)

Kim, Min-kang;Woo, Sung-hee;Cho, Young-bok
- Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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- 2019.05a
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- pp.367-371
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- 2019
'Scientificization' of oriental medicine is a task to be preceded for K-MEDI in the world. Also, We are trying to secure efficacy and safety through scientifically proving the efficacy of Oriental medicine. This paper. We propose a biomarker extraction algorithm for genetic lesion reading of Oriental medicine. Also, A variety of applications in terms of Oriental medicine. Oriental medicine was suggested as a basis for the diagnosis and treatment of the treatment.
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Effects of Soy Isoflavone Intake on Urinary and Fecal Excretion of Daidzein and Genistein in Ovariectomized Rats (대두 이소플라본 섭취수준이 난소절제한 흰쥐에서 Daidzein과 Genistein의 뇨와 변 중 배설에 미치는 영향)

Nam, Hae-Kyung;Kim, Sun-Hee
- Journal of the Korean Society of Food Science and Nutrition
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- v.34 no.1
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- pp.27-35
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- 2005
This study was performed to determine the effect of three different concentrations of soy-isoflavones on excretions through urine and feces in either sham-operated or ovariectomized female rats. Seventy-two 16-week old Sprague-Dawley rats underwent sham operation or bilateral ovariectomy. They were provided diets containing different levels of soy isoflavones for 6 weeks: 50 ppm (low isoflavone intake; LI), 250 ppm (medium isoflavone intake; MI) and 500 ppm (high isoflavone intake; HI). The subsequent fecal and urinary excretions of daidzein and genistein were then measured. In the sham operated rats, body weight gains and food efficiency ratio of the MI and HI groups were significantly lower than control group, while food intake was not different. However, there was no significant difference in ovariectomized rats. The fecal excretion of daidzein was significantly higher in the HI group than the LI and MI groups, and that of genistein increased as dietary isoflavone intakes increased in both the sham operation and ovariectomy. The reverse tendency of fecal recovery was shown with dietary isoflavone dose only in genistein among ovariectomized rats. When dietary isoflavones were increased from 50 ppm to 500 ppm, the amounts of daidzein and genistein in the urine increased dose-dependently. The higher intakes of isoflavones leaded to lower recovery rates of daidzein and genistein in the urine in the sham-operated rats but not in the ovariectomized rats. The urinary recovery was significantly higher in the LI group than the MI and HI groups in the sham-operated rats. The excreted amounts and recovery of the two isoflavones in the urine were higher in the sham operated groups than in the ovariectomized groups, which implied an increased bioavailability of isoflavones by ovariectomy. Therefore, the results suggest that a more efficient use of soy isoflavones in ovariectomized conditions may occur, which indicates that a higher dose of soy isoflavones is necessary for the postmenopausal states.
https://doi.org/10.3746/jkfn.2005.34.1.027 인용 PDF KSCI

Fundamental Studies for the Production of Korea Ginseng(Panax ginseng)(II) -Study on the Variations and the Correlations of Important Quantitative characters of Korea Ginseng according to Environmental Conditions (우량인삼생산(優良人蔘生産)을 위(爲)한 육종생리학적(育種生理學的) 연구(硏究)(II) -재식위치(栽植位置)에 따르는 인삼(人蔘)의 주요량적(主要量的) 형질(形質)의 변이(變異)와 그 상호간(相互間)의 관계(關係))

Choi, B.Y.;Park, J.S.;Kim, Y.R.;Kim, M.K.;Jo, J.S.;Kim, C.S.
- Korean Journal of Agricultural Science
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- v.2 no.1
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- pp.131-142
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- 1975
This study was carried out to define the variations of important quantitative characters and correlations among them accoding to the planted location under the shadow by planting density. The results obtained are summarized as follows; 1. Growth of leaf and stem of 6 rows and 8 rows planting plots was decreased at front and back rows, but that of root was increased at front row and also decreased at back row. However, at 4 rows planting plots, front row was better for the growth of leaf, stem and root. 2. Average root weight of 6 rows planting plot was 34.29g but that of 8 rows planting plot was ]8.20 g. And total weight of root per unit area was increased and quality of ginseng was better in 6 rows planting plot compaired with 8 rows. 3. Variation by planting locations under the shadow was smallest in stem diameter and highest in root length at 8 row planting plot, but at 6 rows planting plot, that was smallest in leaf blade and greatest in stem length. However, in 4 rows plant ing plot, variation of leaf length was smallest and that of root weight biggest. 4. In all Planting densities, root weight was significantly correlated with root diameter and high correlation was recognized between root diameter and stem diameter. 5. Rate of variations of all characters among plant individuals was different by planting location and that of correlations between quantitative Characters too.
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