• Title/Summary/Keyword: 변이음

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Spectroscopic Analysis of Partially Folded State of Ubiquitin (유비퀴틴 단백질의 부분적으로 폴딩된 구조에 대한 분광학적 분석)

  • Park, Soon-Ho
    • Applied Biological Chemistry
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    • v.46 no.4
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    • pp.305-310
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    • 2003
  • Hydrophobic core variant of ubiquitin appeared to have partially folded structure at pH around 2. The intrinsic tryptophan fluorescence emission maximum of this ubiquitin variant at pH 2 showed slight blue shift compare to that of unfolded state, suggesting that some residual tertiary structures remain in this solvent condition. At the same solvent condition, this ubiquitin variant binds with hydrophobic dye, 8-anilinonaphthalene-1-sulfonic acid(AMS), which is known to bind to exposed hydrophobic surface. Furthermore, far-UV circular dichroic spectrum of this ubiquitin variant in the diminished pH was remarkably different from the far-UV CD spectrum of the native state or unfolded state. Based on the molar ellipticity at 220 nm, this ubiquitin variant at pH 2 appeared to have significant amount of secondary structures. All these observations suggest that this ubiquitin variant in the diminished solvent pH has loosely folded hydrophobic core with some secondary structures, which are key features of molten globule conformation. Since molten globule has long been considered as a protein folding intermediate, it is considered that this hydrophobic core variant ubiquitin will serve as a valuable model to study protein folding process.

Studies on Mycogone perniciosa as Variable Strain in Cultivated Mushroom of Agaricus bisporus (양송이 마이코곤병원균(病原菌) 약리균주(藥理菌株)에 관한 연구(硏究))

  • Kim, Gwang-Po
    • The Korean Journal of Mycology
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    • v.9 no.2
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    • pp.93-97
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    • 1981
  • The new strains of Mycogone perniciosa which could attack cream colored mushroom were collected and tested to find out their characteristics in comparison with the original strains. The optimum temperature for mycelial growth was $25^{\circ}C$, showing no difference between strains, but optimum pH was 6.0 for the original strains and pH 7.0 for the new ones. New strains did not survive at $50^{\circ}C$ for 60 minutes while original ones 40 minutes. Delan and Hamai were effective for controlling new strains and the mushroom strains which have scales showed resistance to the new strains of Mt. perniciosa regardless of the mushroom colors.

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Retrospective study on marginal bone loss around maxillary anterior implants with or without bone graft (상악 전치부에서 골 이식 유무에 따른 임플란트 변연골 소실에 관한 후향적 연구)

  • Hwang, Hee-Sun;Jung, Ji-Hye;Kim, Yu-Lee
    • The Journal of Korean Academy of Prosthodontics
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    • v.54 no.2
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    • pp.103-109
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    • 2016
  • Purpose: This study is to evaluate the clinical significance of implantation with simultaneous bone graft by comparing the marginal bone loss around maxillary anterior implants with or without bone graft. Materials and methods: Patients treated with implant-retained restorations on maxillary anterior region at Implant Center, Dental Hospital, Wonkwang University between June 2011 and May 2014 were included in this study. Date of implant placement, implant diameter, implant length, implant-abutment connection type and whether the bone graft was done were investigated. The patient's periapical radiographs taken immediately after implantation and at the most recent visit were compared. Marginal bone loss was measured using Emago advanced v5.6 program (Oral diagnostic systems, Amsterdam, Netherlands). Statistical analysis was done in independent t-test by using SPSS 22.0 program. Results: As a result of observing on 83 implants (without bone graft: 44, with bone graft: 39) of 52 patients for 6 - 45 months (average: 18.4 months), implants without bone graft showed $1.42{\pm}0.42mm$, implants with bone graft showed $1.28{\pm}0.45mm$ of marginal bone loss. Conclusion: In limitations of this study, implants with simultaneous bone graft had significantly less marginal bone loss than implants without bone graft.

Influential Factors for the Sexual Quality of Life in Married Men and Women in Their 40s (40대 기혼남녀의 성생활의 질(SQOL)에 미치는 요인)

  • Yang, Eun-Young;Jang, Young-Eun
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.16 no.10
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    • pp.7219-7226
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    • 2015
  • The purpose of this study was to examine the relationship of 22 selected variables for the sexual quality of life(SQOL) of married men and women in their 40s in an effort to lay the foundation for the development of intervention programs geared toward promoting the sexual health of married middle-aged men and women. The selected variables were eight demographic ones, eight sex-related ones and sex marital relationship ones. The subjects in this study were the visitors of four different health examination centers in Seoul. Two of the health examination centers were located in the region of Gangnam, and the others were located in the area of Gangbuk. After a survey was conducted from January 19 to March 5, 2015, the answer sheets from 187 respondents who were aged between 40 and 49 were analyzed. As a result, academic credential(p<.05), health status(p<.001), duration of marriage(p<.01) and monthly mean income(p<.01) were identified significant demographic variables to affect the sexual quality of life. Among the sex-related variables, the level of sex knowledge(p<.01) and exposure to pornography exercised(p<.001) and the husband's participation in delivery(p<.001) had a significant influence the sexual quality of life. All the variables of marital relationship that were marital dilemma(p<.05), the frequency of sexual relations(p<.001), love toward the spouse(p<.001), overall family harmony(p<.001), nonsexual communication(p<.001) and sexual communication(p<.001) had a significant impact on the improvement of the sexual quality of life. In conclusion, the variables of marital relationship were found to have been more important factors to affect the improvement of the sexual quality of life than the demographic and sex-related ones.

Effect of Implant Preload on the Marginal Bone Stresses Studied by Three Dimensional Finite Element Aanalysis (임플란트 고정체와 지대주 간의 전하중 크기가 골응력에 미치는 영향에 대한 유한요소해석)

  • Nam, Hyo-Jun;Jo, Kwang-Hun
    • Journal of Dental Rehabilitation and Applied Science
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    • v.28 no.2
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    • pp.127-138
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    • 2012
  • This study is to assess the effect of preload level on the stress development at the marginal cortical bone surrounding implant neck. A finite element model was created for a single implant placed in the lower jaw bone. An external load of 100N was applied on the top of abutment at 30 degree with the implant axis in lingo-buccal direction. Five different preloads, i.e. 0, 200, 400, 600, 800N were applied to the abutment stem to investigate if and/or how the preload affects on the marginal bone stress. Differences in the marginal bone stress were recorded depending on the level of preload. On the other hand, the tensile stress on the marginal cortical bone decreased in models of higher preload. Preloads between abutment/fixture can increase compressive stresses in the marginal cortical bone although the amount may be insignificant as compared to those generated by functional forces.

3D 콘텐츠의 미래와 스토리텔링

  • Jeon, Hye-Jeong
    • Information and Communications Magazine
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    • v.27 no.3
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    • pp.17-22
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    • 2010
  • 최근 들어 3D에 관한 관심이 높아지면서 각종 기술적인 이슈는 물론 3D 콘텐츠의 제작 방향에 대한 논의가 활발하게 이루어지고 있다. 흔히들 3D 콘텐츠라고 부르는 것은 현재로선 어떤 특정한 장르나 엄정한 정의를 가진 용어라기보다는 일종의 새로운 매체기술을 위한, 매체 기준적인 콘텐츠의 분류 형태라고 볼 수 있을 것이다. 따라서 3D 콘텐츠라는 용어를 새로이 썼다고 해서 좋은 콘텐츠가 지녀야 할 근본적인 요소가 달라지는 것은 아니다. 물론 매체의 발전과 변화에 따라 대중들의 가치관, 예술적 시대적 패러다임, 근본적인 인간의 생활방식까지 바뀔 수 있다는 것은 자명한 사실이다. 이는 회화 문화에서 사진의 등장으로, 사진에서 동영상으로, 영화에서 TV와 비디오로, 그리고 아날로그에서 디지털로의 중심 이동이 인간의 삶에 얼마나 큰 변화를 초래했는지만 상기해봐도 쉽게 알 수 있다. 그러므로 3D기술이 가진 파급효과와 영향력이 어디까지인지 쉽게 단정할 수는 없는 것이다. 그러나 언급했듯이 어떤 콘텐츠라도 결국엔 인간이 향유하리란 점은 분명한 사실이다. 현재는 3D 콘텐츠의 제작 방향에 대해서 지나치게 매체 중심적으로 접근하려는 경향이 있는데, 역사적으로 언제나 인간에게 매력적이었던 콘텐츠의 기본은 변함이 없었다. 변하는 것은 오히려 매체나 기술, 하드웨어 쪽이었다. 따라서 콘텐츠를 매체에 이식하는 가변적인 내용물쯤으로 이해하는 기술중심의 사고에서, 인간이 근본적으로 원하는 이야기 콘텐츠를 구현하기 위해 매체가 변해왔다는 점을 이해해야 하는 콘텐츠 중심 사고도 할 필요가 있는 것이다. 본고에서는 과거 많은 매체들의 역사를 통해 새로운 매체 기반에서의 콘텐츠의 모습이 어떻게 변해왔는지를 되짚어 보려고 하며, 이를 통해 앞으로 3D 콘텐츠의 향방을 유추해 볼 기회를 마련하고자 한다.

Vibration Characteristics of Tapered Piles Embedded in an Elastic Medium (탄성매체에 근입된 변단면 말뚝의 진동 특성)

  • Oh, Sang-Jin;Kang, Hee-Jong;Lee, Jae-Young;Park, Kwang-Kyou;Mo, Jeong-Man
    • Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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    • 2005.05a
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    • pp.832-835
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    • 2005
  • The free vibration of tapered piles embedded in soil is investigated. The pile model is based on the Bernoulli-Euler beam theory and the soil is idealized as a Winkler model for mathematical simplicity. The governing differential equations for the free vibrations of such members are solved numerically. The square tapered piles with one free and the other hinged end with rotational spring are applied in numerical examples. The lowest two natural frequencies are obtained over a range of non-dimensional system parameters: the rotational spring parameter, the embedded ratio, the foundation parameter, the width ratio of the contact area and the section ratio.

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Critical Loads of Tapered Cantilever Columns with a Tip Mass (자유단 집중질량을 갖는 변단면 캔틸레버 기둥의 임계하중)

  • Jeong, Jin Seob;Lee, Byoung Koo;Kim, Gwon Sik;Kim, Jong Ung
    • Journal of Korean Society of Steel Construction
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    • v.17 no.6 s.79
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    • pp.699-705
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    • 2005
  • This paper investigates critical loads of tapered cantilever columns with a tip mass, subjected to a follower force. The linearly tapered solid rectangular cross-sections are adopted as the column taper. The differential equation governing free vibrations of such columns, also called Beck's columns, is derived using the Bernoulli-Euler beam theory. Both divergence and flutter critical loads are calculated from the load-frequency curves that are obtained by solving the differential equation. The critical loads are presented as functions of various non-dimensional system parameters, namely, the taper type, the subtangential parameter, and the mass ratio.

Hierarchical Disparity Estimation for Image Synthesis in Stereo Mixed Reality (스테레오 혼합 현실 영상 합성을 위한 계층적 변이 추정)

  • 김한성;최승철;손광훈
    • Journal of Broadcast Engineering
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    • v.7 no.3
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    • pp.229-237
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    • 2002
  • Natural synthesis of real and virtual images is a key technology in mixed reality. For this purpose, we propose an efficient dense disparity estimation algorithm and a synthesis algorithm considering features of stereo images. Dense disparities are estimated hierarchically from the low to high resolution images. In the process, the region-dividing-bidirectional-matching algorithm makes matching process efficient and keeps the reliability of the estimated disparities, and dense disparities are assigned considering edge information. finally, mixed reality stereo images are synthesized by comparing depth data of real and virtual Images. Computer simulation shows that the proposed algorithms estimate very stable disparity vectors with sharp edge and synthesize natural stereo mixed reality images.

Environmental Pollution and Geochemical Behavior of Heavy Metals in Roadside soil and Settling Particles from Retention Pond, A-71 Motorway, France (프랑스 A-71 고속도로변 토양과 부유퇴적물의 중금속의 지화학적 거동과 오염 연구)

  • 이평구
    • Proceedings of the Korean Society of Soil and Groundwater Environment Conference
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    • 1997.05a
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    • pp.30-38
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    • 1997
  • 고속도로변에 설치된 retention pond는 drainage system의 일부분으로 우기에 빗물의 양을 조절하고 고속도로 노면에서 운반되어 retention pond에 유입된 오염된 입자를 침전, 제거시키기 위해 설치되었다. 빗물에 입자상태로 이동된 납, 아연, 카드뮴를 제거하기 위해 설치된 retention pond의 효과를 평가하기 위해 수리지질학적 연구 및 부유퇴적물의 물리화학적 특징을 규명하기 위한 연구가 수행되었다. 부유퇴적물과 비교하기 위해 심하게 오염된 roadside soil과 오염되지 않은 background soil에 대해서도 연구가 수행되었다. 부유퇴적물의 중금속함량은 background Sologne soil에 비해 원소에 따라 2-8배 높다. 그러나, roadside soil의 중금속함량은 부유퇴적물에 비해 7-26배 높다. Sequential extraction methods를 이용하여 분석한 결과 심하게 오염된 roadside soil에 존재하는 납, 아연, 카드뮴은 대부분 쉽게 용해될 수 있는 상태 (Fraction FII, FIII)로 존재하며 반면에 규산염광물과 수반되는 금속함량의 비율은 매우 낮다. 부유퇴적물에서는 규산염광물과 수반되는 금속함량이 전체 금속함량의 1/3까지 크게 증가한다. Roadside soil 과 부유퇴적물사이의 중금속함량 차이가 매우 큰 것은 중금속의 대부분이 retention pond에 이르기 전에 고속도로변과 배수로 일부에 축적되어 모두 상실하기 때문이다.

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