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Efficacy of Weekly 0.1% Amitraz Dip with 4% Chlorhexidine Shampoo on Juvenile Onset Generalized Pyodemodicosis Unresponsive to Ivermectin Therapy in Japanese Chin Dog (Japanese Chin 종에서 발생한 Ivermectin에 반응을 보이지 않은 전신성 농성 모낭충 감염증에 대한 0.1% Amitraz와 4% Chlorhexidine의 국소치료 일례)

  • Jeong, Hyo-Hoon;Jeong, A-Young;Hoh, Woo-Pil;Eom, Ki-Dong;Lee, Keun-Woo;Oh, Tae-Ho
    • Journal of Veterinary Clinics
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    • v.20 no.2
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    • pp.237-241
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    • 2003
  • A case of juvenile onset generalized demodicosis of one year old, intact female Japanese Chin dog weighing 3.1kg was presented to the Small Animal Clinic of the College of Veterinary Medicine of Kyungpook National University. The diagnosis was made based on the physical examination, deep skin scrapings, hematology, serum chemistry, endocrinologic evaluation and bacterial culture. Numerous D. canis mites of various stages were observed in multiple skin scraping samples. CBC, serum chemistry, $T_3$, $T_4$ and free $T_4$ values were within normal range and Staphylococcus intermedius was isolated in bacterial culture of pustules. The dog was healthy other than skin lesions at the presentation. The three different treatment protocols were tried for the case. No clinical improvement was observed during 13 weeks of orally given daily basis ivermectin therapy at 600ug/kg and 2 weeks of spot-on weekly basis selamectin therapy at 30 mg/kg with cephalexin given orally twice a day at 25 mg/kg. However, a remarkable remission was seen by 0.1% amitraz dip on weekly basis with 4% chlorhexidine bath given twice a week. The secondary staphylococcal infection and accompanied pruritus was almost disappeared in two weeks and she was recovered clinically normal in 9 weeks of therapy. The therapy was continued for 4 more weeks to prevent relapse. The dog is clinically normal and being monitored for development of any abnormal dermatological signs for the time being.

Weed Flora Changes in Lowland Rice Field in Gangweon Province (강원지역(江原地域) 지대별(地帶別) 논잡초(雜草) 분포(分布))

  • Kim, K.S.;Kim, J.R.;Ko, J.H.;Sa, J.G.;Chang, J.S.;Kim, D.Y.
    • Korean Journal of Weed Science
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    • v.14 no.4
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    • pp.258-264
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    • 1994
  • The weed survey in lowland rice field in 1992 was conducted to identify weed population change as affected by different elevation, soil type and cultivation pattern at Gangweon province. There were more perennial weeds in plain and east coastal area while more annual weeds in mid alpine and alpine area. Meanwhile, perennial weed species was more dominant at ordinary and sandy soil but annual weed species was more dominant at poorly drained soil. In general, hand and machine(30 day old seedling) transplanting would result in higher dominant weed species of perennial while there was more annual weed species in machine (10 day old seedling) transplanting and dry seeding, respectively. Also, annual weed species was more predominant at spring plowing time compared to autumn plowing time. Particularly, there was change in dominant weed species with time. In 1971 annual weed species was more predominant but perennial weed species was highly dominant in 1981 and 1992.

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Altered Expression of ${\beta}_3$ Integrin on Sclerotic Aortic Valves in a Hypercholesterolemic Rabbit Model (고콜레스테롤혈증을 유발한 토끼의 대동맥 판막에서 ${\beta}_3$ Integrin 발현의 변화)

  • Park, Chan-Beom;Kim, Young-Du;Choe, Mi-Sun;Jin, Ung;Moon, Seok-Whan;Kim, Yong-Han;Kim, Chi-Kyung;Jo, Keon-Hyon;Kweon, Jong-Bum
    • Journal of Chest Surgery
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    • v.41 no.6
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    • pp.687-694
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    • 2008
  • Background: Although aortic valve sclerosis causes no significant hemodynamic alterations, it is associated with an increased risk of cardiovascular death and myocardial infarction. However, the role of ${\beta}_3$ integrin in aortic valve sclerosis remains unclear. Material and Method: Twenty male New Zealand rabbits were divided into two groups. Group 1 rabbits (n=10) received a normal chow diet, while group 2 (n=10) rabbits received a diet containing 1% cholesterol for 12 weeks. After the rabbits were euthanized, their aortic valves and ascending aortas were excised for analysis. Result: Total serum cholesterol ($2,148.3{\pm}1,012.5\;mg/dL$ versus $53.7{\pm}31.8\;mg/dL$, p<0.05), triglyceride ($240.4{\pm}218.3\;mg/dL$ versus $31.6{\pm}6.4\;mg/dL$, p<0.05), and low density lipoprotein (LDL)-cholesterol($2,065.3{\pm}960.9\;mg/dL$ versus $29.1{\pm}30.9\;mg/dL$, p<0.05) levels were significantly higher in the cholesterol diet group compared with the normal diet group. Myofibroblasts and macrophages were more highly expressed in the aortic valve leaflets of rabbits in the cholesterol diet group than of those in the normal diet group. A real-time polymerase chain reaction revealed decreased ${\beta}_3$ integrin mRNA levels in the hypercholesterolemic aortic valves and aortas. Conclusion: The present study shows that hypercholesterolemia induces aortic valve sclerosis. These findings suggest that alterations in ${\beta}_3$ integrin may playa role in the development of aortic valve sclerosis.

Emission of Green House Gases in the Agricultural Environment -1. The Cropping System and Emission of the Green House Gases-CO2, CH4, N2O)-under Different Cropping System (농작물(農作物) 재배환경(栽培環境)과 지구온난화(地球溫暖化) 원인(原因)가스 발생(發生) -1. 답전전환시(畓田轉換時) 작부체계(作付體系)와 지구온난원인기체(地球溫暖原因氣體) -이산화탄소(二酸化炭素), 메탄, 아산화질소(亞酸化窒素)- 발생(發生))

  • Lee, Sang-Kyu;Suh, Jang-Sun
    • Korean Journal of Soil Science and Fertilizer
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    • v.26 no.1
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    • pp.49-56
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    • 1993
  • The net flux of global green house gases such as carbon dioxide($CO_2$), methane($CH_4$), and nitrous oxide($N_2O$) emitted from the rotation of paddy-upland soil during growing sesaon under different cropping system was determined. The results obtained were summarized as follows : 1. The net flux of $CO_2$ during the growing season was the highest from continuous cultivation of rice but the lowest from rotation cultivation of rice-soybean. Under the different cropping system the highst emission was from soil of continuous cultivation of rice, but the lowest from converted system. 2. The net emission of methane was the highest from the sold of continuous cultivation of rice, but the flux was remarkably decreased by differing the cropping system. 3. $N_2O$ was emitted greatly from the every two year rotation of potato-chinese cabbage and the next rank was from continuous cultivation of rice, but was decreased notably from rotation cultivation of rice-soybean and potato-chinese cabbage under rotation of paddy-upland cropping system. 4. The ratio of oxygen and carbon dioxide in the soil air was much different with glowing season, the ratio was varied with 4~10 percents for oxygen and 1~22 percents for carbon dioxide. The ratio of carbon dioxide was dozens or hundreds times to that of air, and the variation was very high also. 5. The emission of global green house gases such as carbon dioxide, methane and nitrous oxide was affected by the moisture, temperature and nutrients of soils and the growth period of crops.

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Impacts of Oyster Shell and Peat Treatments on Soil Properties in Continuous Watermelon Cropping Greenhouse Plots (패화석 및 이탄 처리가 수박 연작지 토양의 특성에 미치는 영향)

  • Ahn, Byung-Koo;Lee, Jin-Ho;Lee, Young-Han
    • Korean Journal of Soil Science and Fertilizer
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    • v.43 no.4
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    • pp.438-445
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    • 2010
  • Soils in continuous monoculture cropping system generally have a number of physical and chemical problems. Thus, we studied to investigate selected soil properties in continuous watermelon cropping plots with applications of different soil management practices: 1) conventional farming practice (CFP), 2) chemical fertilizer management practice (FMP), the FMP with different amounts, 0.5, 1.0, and 1.5 t $ha^{-1}$, of oyster shell meal application (FMP-OS 0.5, 1.0, and 1.5 t $ha^{-1}$), and 3) the FMP with different amounts, 2.0, 3.0, and 4.0 t $ha^{-1}$, of peat application (FMP-PT 2.0, 3.0, and 4.0 t $ha^{-1}$) and also to evaluate watermelon quality. Soil pH slightly increased only in the FMP-OS 1.5 t $ha^{-1}$ plot, while it was not changed or decreased a little in other plots. The contents of soil organic matter (SOM) expectedly increased in the FMP-PT plots, whereas it markedly decreased in the FMP-OS plots. The concentrations of exchangeable cations, $Ca^{2+}$, $Mg^{2+}$, and $K^+$, in soils were mostly dropped down in most of the FMP and FMP-PT plots. Otherwise, the exchangeable $Ca^{2+}$ concentration increased a bit in the FMP-OS plots. Also, the concentrations of water-soluble anions, $NO_3^-$, $Cl^-$, ${SO_4}^{2-}$, and ${PO_4}^{3-}$, in soils mostly declined in all the plots applied with the different management practices during the study years. Due to the cation and anion decreases, the electrical conductivity (EC) values in the soils were greatly reduced in the plots. Thus, the soil management practices applied, especially oyster shell meal and peat treatments, might be useful to control soil conditions. However, watermelon quality, such as sugar content and fruit weight, would not be associated with the soil management practices applied.

The morphological characteristics and fatty acids composition of pollens in acorn and darae(Actinidia arguta) (도토리화분과 다래화분의 일반성분, 지방산 분석 및 형태 관찰)

  • Hong, In-Pyo;Lee, Man-Young;Woo, Soon-Ok;Sim, Ha-Sik;Choi, Yong-Soo;Han, Sang-Mi;Kim, Hye-Kyung;Byeon, Kyu-Ho;Lee, Myeong-Lyeol;Kim, Jung-Bong
    • Journal of Sericultural and Entomological Science
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    • v.51 no.2
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    • pp.119-122
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    • 2013
  • Pollens have been known to possess various biological properties. Therefore, pollens have been extensively used in functional food, folk medicine, and beverage industry to improve human health. This study was conducted to establish the optimized protocol for cytoplasm isolation of bee pollen. Data of biochemical parameters and fatty acid profiles were obtained from pollens of Acorn and Darae(Actinidia arguta). Contents of crude protein and crude fat were 24.1% and 11.8% in Acorn pollen, and those of Darae pollen showed 35.8% and 8.7% in crude protein and crude fat respectively. Also after lyophilizing of Acorn pollen, content of crude protein was increased to 26.5%. Main fatty acids were palmitic acid(C16 : 0), oleic acid(C18 : 1), linoleic acid(C18 : 2) and linolenic acid(C18 : 3) in bee pollen. Linoleic acid(37.3%) was dominant fatty acid in Acorn pollen that is one of essential fatty acids. Linolenic acid(48.3%) was dominant fatty acid in Darae pollen that is a polyunsaturated fatty acid. The proportion of unsaturated fatty acids to total acid content was 73.2% in Acorn and 63.2% in Darae pollen, and especially that of polyunsaturated fatty acids was higher than 55%.

Mortality Change of North Korean People and its Association with State Production and Welfare System (경제 위기 전후 북한 주민의 사망률 동태의 특성과 변화)

  • Park, Keong-Suk
    • Korea journal of population studies
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    • v.35 no.1
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    • pp.101-130
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    • 2012
  • This study examines mortality change in North Korea and its association with state production and welfare systems. Two main subjects are analyzed. The first theme is to examine the reliability of mortality related data released by North Korea government authorities. Examining inner consistencies among mortality related statistics and comparing with mortality trends in other socialist societies, the study finds that mortality rate was under estimated. Under-estimation of mortality by North Korean authorities is regarded to result not only from political purpose which aims to propagate the regime's superiority but also from enumeration errors of vital statistics based on the residence registration. The second theme is to estimate the change in mortality of North Korean people since the establishment of DPRK, correcting errors of mortality data. Mortality of North Korean people is estimated to have improved largely by the early 1970s, to have been sluggish hereafter, and finally to have increased during the economic hardship period between 1993 and 2008. While large people died during the food crisis in the late 1990s, however the population loss caused by mortality increase was not so great as the proposition of the huge starvation was expected. It is partly because population turbulence occurred not just by mortality increase, rather it has progressed in the joint effects of fertility decline and exodus of North Korean people for food. It is also due to North Korean people's voluntary activities of informal economy. It is also worth noting the high mortality rate of North Korean men. The high mortality of North Korean men is likely due to men's mobilization for long time in army and labor with high risk of accident and their life styles.

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Geological Structure and Deformation History in the Gwangju area, Gyeonggi-do, Korea (경기도 광주시 일대의 지질구조와 변형사)

  • Lee Hee-Kwon;Kim Man-Kwang
    • The Journal of the Petrological Society of Korea
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    • v.14 no.2 s.40
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    • pp.108-115
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    • 2005
  • Gyeonggi metamorphic complex in the Gwangju area include banded biotite gneiss and quartzofeldspathic gneiss. Detailed structural analysis suggests that structural elements in the study area were formed by at least five phase of deformations. Penetrative compositional foliations(S1) formed in the banded gneiss during the first metamorphism and deformation (D1). After intrusion of plutonic rocks, the second deformation (D2) produced S2 foliations in the banded gneiss and quartzofeldspathic gneiss during the second metamorphism. D3 structures are represented by isoclinal folds (F3) whose axial surfaces are parallel to S3 foliations. The N-S oriented shortening (D4) was accommodated by closed upright F4 fold with about 100m of axial surface separation. F4 fold is refolded by regional F5 folding resulting in different orientation and fold style of F4 fold according to the position of F5 fold. The F4 fold with tight interlimb angle is subparallel to the axial surface (north-south) of F5 fold in the core of the F5 fold. In contrast the F4 fold trends northeast in the western limb and northwest in the eastern limb of F5 fold. The interlimb angle is larger in the limbs than that in the core of F5 fold. The trace of foliations is constrained by mainly F4 and F5 folds. Joint fanning around fold is developed in the limbs of F5 fold and bc joints are dominant in the hinge area of F5 fold. A strike-slip fault had developed in tile central part of the study area after F5 folding. The orientation of joint and foliation is rotated anticlockwise about $15^{\circ}$ by the landslide occurred during the Quaternary.

Determine the effects of drying temperature on the quality change and antioxidant activity characteristics of blueberry (건조 온도에 따른 블루베리의 품질변화 및 항산화특성)

  • Shin, Dong-Sun;Yoo, Yeon-Mi;Kim, Ha-Yun;Han, Gwi-Jung
    • Food Science and Preservation
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    • v.22 no.4
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    • pp.505-511
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    • 2015
  • This study was performed to investigate the effect of drying temperature on the quality characteristics and antioxidant activity of blueberry. Blueberries were dried at different times and temperatures, including A ($40^{\circ}C$, 72 hr), B ($40^{\circ}C$, 48 h and $50^{\circ}C$, 24 hr), C ($50^{\circ}C$, 72 hr), and D ($60^{\circ}C$, 72 hr). The yield and pH ranges of blueberry were determined to be 17.73~31.17% and 3.20~3.25, respectively. The yield rate of A treatments, soluble solid of D treatments, was the highest. The yield rate and soluble content was the highest in the treatment of A and D, respectively. The moisture content and water activity were significantly decreased with the increase in drying temperature (p<0.05). The L value of A treatment, and a and b values of D treatment were the greatest. In the analysis of texture analyzer, hardness, springiness, cohesiveness, gummiess and chewiness were significantly increased with the increase in drying temperature (p<0.05). In the sensory evaluation of blueberry, the appearance and color were the highest in the A treatment. The moisture, texture and taste was highest in the B treatment. The overall acceptability was in the order of B > A > C >D. The total polyphenol content and DPPH radical-scavenging activity were 9.21~13.05 mg/GAEg and 61.90~81.42%, respectively, which were significantly decreased with the increase in drying temperature (p<0.05). Therefore, the optimum time and temperature for blueberry drying was founded to be B treatment ($40^{\circ}C$, 48 hr and $50^{\circ}C$, 24 hr) among other treatments.

음료$\cdot$다류 산업

  • 손헌수
    • Food Industry
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    • s.180
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    • pp.27-64
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    • 2004
  • 국내 제조업 전체에서 식음료품은 $6.31\%$를 차지하고 있다. 2000년을 기준으로 식품산업의 총매출실적을 보면 32조 3,463억원을 기록하고 있는데, 이 중 식료품은 26조 921억원, 알콜올음료를 포함한 음료품은 6조 2,516억원을 차지하고 있다. 2001년, 음료시장의 규모는 약 2조 7,900억원 정도였다. 빠르게 성장하던 전체 음료시장의 매출은 IMF 이후 약간 주춤하는 경향을 보였지만 지속적으로 매출액이 상승하여 2002년에는 3조 4천억원의 매출을 기록하였다. 이것은 사이다, 후레바, 정통주스, 냉장주스, 스포츠 음료, 두유 및 기능성음료 등이 성장을 주도하였다. 2003년 상반기, 1조 6,500억원으로 전년 동기대비 $3\%$ 감소하였지만 2003년 전체 실적은 대략 지난해와 비슷한 3조 5,000억원 규모로 전망된다. 내수량의 경우 탄산음료와 과즙음료가 감소하는 경향을 나타냈지만, 전체적으로는 증가하였다. 다류시장의 규모는 약 650억원, 캔커피시장의 규모는 2,400억원 정도로 나타났다. 이처럼 음료$\cdot$다류 시장은 전체적으로 약 4조원의 거대시장규모를 형성하고 있으며 내수가 지속적으로 증가되고 있어, 점차 시장규모도 증가할 것으로 전망되고 있다. 최근에는 기능성 음료 및 다류의 시장규모가 전체의 $20\%$에 달할 정도로 신장하였으며, 기능성음료 및 다류의 특허출원도 지속적으로 증가하고 있는 실정이다. 이는 비단 국내에서 뿐만 아니라 세계적인 현상이며 이러한 추세는 앞으로 지속될 것으로 전망되고 있다. 이처럼 기능성음료 및 다류의 성장이 두드러지고 있는 것은 시대가 변하면서 현대인들의 생활방식과 식생활 변화, 질병형태 다양화 등 여러 사회적 여건이 변화되고 있는데 기인하며, 현대인의 건강에 대한 관심의 증대는 음료시장의 쾌속성장과 틈새수요를 지속적으로 창출하고 있다. 현재 세계 건강기능성 식품의 시장 규모는 약 160조원이며, 국내의 경우 약 1조원에 이르는 실정이다. 이 중 기능성음료 시장은 국내에서 약 4천억원 규모로 기능성식품 시장의 $40\%$를 차지하고 있다. 이처럼 기능성음료 시장은 최근 연간 $7\%$ 정도의 빠른 성장률을 보이고 있으며 향후에도 $6.7\%$의 실질 연간 성장률을 지속할 것으로 전망되고 있다. 전해질(이온)음료나 식이섬유를 포함하는 다이어트음료에서 출발한 기능성음료는 숙취해소, 성인병 예방, 스트레스 해소에 이르기까지 각종 질병의 치료 및 예방으로 확대되고 있다. 앞으로는 BT 및 나노 기술 등을 이용한 신기능 소재들에 대한 다각적인 효능의 규명에 따른 음료$\cdot$다류 소재의 개발과 더불어 체질개선, 다이어트, 숙취해소 등의 특정한 기능성과 관련한 음료$\cdot$다류의 특허출원이 계속될 것으로 전망된다. 복잡한 한약의 제조과정을 단순화하여 티백이나 캔 형태로 만든 맛과 기능이 조화된 음료$\cdot$다류 분야의 연구개발이 지속될 것으로 보이며, 시장 규모의 확대와 더불어 기능성과 간편성을 동시에 추구하는 신세대 소비자들의 성향을 겨냥하여 기존의 음료$\cdot$다류 전문 업체 외에도 제약회사 등의 비음료 업체도 다양한 형태의 음료$\cdot$다류 기술개발을 지속할 것으로 예상되고 있다. 특히 새로운 신기능성 소재를 개발하는 것은 고부가가치 기술로써 BT, NT 등의 최첨단 기술의 발전과 도입으로 인해 그동안 수입에 의존하던 기능성 소재들도 국내 기업들의 축전된 기반기술을 통하여 대거 참입할 것으로 보인다. 하지만, 여러 업체의 음료$\cdot$다류시장 진출에 따라 야기될 수 있는 비위생이고 효능이 불확실한 식품의 유통, 업체간의 과열경쟁에 따른 유통질서 문란 등은 모처럼 활기를 되찾은 음료$\cdot$다류 분야의 기술개발을 위축시킬 수도 있으므로 정부차원에서 체계적이고 효율적인 관리가 조속히 이루어져야 할 것이며 이를 제도적으로 뒷받침하기 위한 정책이 수립되고 시행되어야 할 것으로 보인다. 특히, 원료적인 측면에서의 무역 불균형은 반드시 해소되어야 할 부분이다. 대부분이 수입 기능성 원료에 의존하고 있는 현실에서 국내의 BT 기술 확충에 더욱 많은 투자와 노력이 집중되어야 할 것이다. 세계적으로 경쟁이 될 수 있는 기능성 소재의 개발과 이를 통한 신기능 음료의 개발은 단순한 수학적 계산을 넘어서 국가의 기술력을 홍보할수 있는 좋은 계기가 되기 때문이다. 바야흐로 음료$\cdot$다류 분야에 대한 열기가 식품시장을 주도하면서, 시장이 안정적으로 확대되기 위해서는 지속적인 기술개발이 이루어져야 한다는 것은 재론의 여지가 없다고 하겠다.

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