• Proceedings of the Korean Society of Veterinary Service Conference
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• 1996.05a
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• pp.70.1-70
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• 1996

• Journal of the korean veterinary medical association
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• v.30 no.3
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• pp.162-171
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• 1994

이 자료는, 국제수역사무국(Office de International Epizooties : O.I.E.)에서 발행한 Manual of Standards for Diagnostic Tests and Vaccines for List A and List B Diseases of Mammals, Birds and Bees(1992) (포유류, 조류, 꿀벌에 있어서의 A급 및 B급 질병에 대한 진단시약 및 예방백신에 대한 표준지침) 중에서 광견병(B8, Rabies)에 관한 내용(Chapter 22, 205-215)을 우리나라의 광견병 방역대책 수립과 생물학적 제제개발을 위한 참고자료로 활용하기 위하여 번역 소개한 것이다. 본래의 원저자는 프랑스의 Dr J. Blancou로서 프랑스 국립수의식품연구원(CNEVA) 산하의 광견병 및 야생동물 병리연구소(Laboratoire d'Etudes sul la Rage et de la Pathologie des Animaux Sauvages)에 책임자로 재직한 바 있으며, 1991년 이후 현재에는 국제수역사무국(O.I.E)의 사무총장(Director-general)직을 맡고 있다.

• KOREAN POULTRY JOURNAL
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• v.38 no.1 s.435
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• pp.126-128
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• 2006

2006년이 다가오면서 우리 양계업계도 보다 좋은 한해가 되기를 기대해 본다. 그러기 위해서는 무엇보다도 질병관리에 심혈을 기울여야만 할 것이다. 특히 아직도 공포를 자아내고 있는 고병원성 조류인플루엔자(HPAI)로부터의 해방 등 당면현안 문제해결에 있다. 지난 8일 본회 회의실에서 정부, 학계, 생산자로 구성된 위생방역대책위원회가 개최되었다. 이날 회의는 김선중 위원장(서울대 수의과대학 교수)을 비롯 13명의 위원이 참석하였으며, 최준구 회장이 배석하였다. 이날 회의는 HPAI 예방 및 발생시 퇴치방안, LPAI 백신개발과 활용방안, 최근 문제되고 있는 뉴모바이러스 대책 등 다양한 주제로 논의가 이루어졌으며, 주요 사항은 정부건의 및 농가 홍보를 통해 문제를 해결해 나간다는 방침이다. 본고는 이날 논의된 주요내용을 중심으로 정리해 보았다.

• Korean Chemical Engineering Research
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• v.46 no.3
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• pp.604-609
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• 2008

This study is about the modeling and simulation of heat transfer in the box for packaging and shipping of vaccines. Comparison of the simulation results with experimental data revealed that a one-dimensional model (a spherical model of using a radius equivalent to the rectangular geometry of box) showed good agreement with experimental data during cooling process but did not successfully simulate heating process. It is considered that a rigorous boundary condition is not properly applied for outer surface of the box. However, we could successfully develop a basic algorithm for simulating heat transfer through multi-slabs combined with different materials including phase change material.

• Korean Journal of Microbiology
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• v.33 no.2
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• pp.97-104
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• 1997

Herpes simpex virus type 2 (HSV-2) infects the genital and oral mucosae of human and other animals. HSV-2 infection is a widespread health problem causing various clinical syndromes including oral, genital, and ocular lesions, viral encephalitis, and recurrent diseases. Hybridorna cell lines secreting a monoclonal antibody (mAb) against the HSV-2 were produced by fusing spleen cells of HSV-2-immunized mice with Sp2/0-AgI4 myeloma cells. One hybridoma cell line was established and its monoclonal C-2, IgM, recognized the antigens of 134, 86, and 43 kDa in western blot analysis. In SDS-P AGE analysis of HSV -2 antigens, 25 bands were separated between 3D kDa and 159 kDa. In indirect immunofluorescent assay, mAbs exhibited binding to the virus antigen expressed on Vero cell infected with HSV-2.

• Journal of the Society of Disaster Information
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• v.17 no.4
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• pp.778-785
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• 2021

Purpose: The study is to analyze the current status of international clinical trial information services related to COVID-19 and to find out the impact of disclosing activities of clinical trial registration on the medical and pharmaceutical industry. Method: To achieve the purpose of the study, this study analyzed the current status of 780 registered clinical trials for COVID-19 during March of 2020 by using regression analysis. Result: The analysis of clinical trial research registration information showed and proved its usefulness for the development of related new drugs, treatments, vaccines, predictive and prognostic diagnostic kits and treatments related to the COVID-19 (Corona 19) in the world. Conclusion: The study concludes and urges all medical and pharmaceutical companies to register their trials on CRIS and recommends utilizing this registered data to develop advanced drug to benefits all patients related to COVID-19.

• Korean Journal of Microbiology
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• v.43 no.1
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• pp.7-13
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• 2007

Pasteurella multocida is one of the important animal pathogen causing widespread infections in various domestic animals. In swine, it causes severe respiratory diseases such as atrophic rhinitis and pneumonic pasteurellosis. To develop the efficient subunit vaccine against swine atrophic rhinitis, we investigated protective antibodies and humoral immunity of outer membrane protein H (OmpH) which is one of the major outer membrane proteins in P. multocida. Outer membrane fraction of P. multocida was immunologically detectable using antisera from both mice groups vaccinated by formalin-killed whole cells and by commercial vaccine. The expression vector for production of recombinant OmpH was constructed and the recombinant OmpH was expressed and purified from E. coli. Recombinant OmpH showed high antigenic and immunogenic properties in mice vaccination and ELISA with antisera.

• Journal of Internet Computing and Services
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• v.22 no.1
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• pp.89-98
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• 2021

Community-acquired pneumonia (CAP) is a major risk factor of mortality in chronic obstructive pulmonary disease (COPD). Streptococcus pneumoniae (colloquially known as pneumococcus) is one of important pathogens of CAP in patients with COPD. Preventive interventions for pneumonia include pneumococcal and influenza vaccinations. A prospective, cohort study has been performed to investigate the protective effects of pneumococcal and influenza vaccinations on the severity of community-acquired pneumonia requring hospital admission in patients with COPD. Seven university-affiliated hospitals in Korea have participated in the study. The aim of this study was to construct an online registration system for the multi-institutional researchers that facilitates efficient collection and management of COPD patient data. This study has presented three basic strategies-accurate data input, convenient data completion, and real-time data management-to supplement the demerits of existing offline clinical study. The proposed online registration system has already been applied to a multi-institutional clinical study and was acknowledged for its high performance.

• Journal of the Korea Society of Computer and Information
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• v.28 no.5
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• pp.129-153
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• 2023

This study was conducted in the context of the Covid-19 pandemic by analyzing a large amount of press report frames regarding the Covid-19 vaccine which is of great public interest, in order to explore the role and direction of trusted media as core elements of crisis communication. The study period lasted for eight months beginning in November 2020 when the development of the Covid-19 vaccine was in progress until June 2021. Set-up as research subjects were the Chosun Ilbo, Joongang Ilbo, Dong-A Ilbo and Hankyoreh according to their public confidence rankings and number of readers.The analysis method used structured topic Modeling (STM) and semantic network analysis. As a result, based on a clear cluster of word structures and a central analysis value, a total of 64 relevant frames, 16 for each news company, were gathered. In the third phase a comparative analysis of the four news companies was carried out to verify the organizational degree of the frames and substantial differences.

• Journal of Yeungnam Medical Science
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• v.25 no.1
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• pp.1-18
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• 2008

Although Lamivudine and adefovir dipivoxil are efficacious drugs for preventing hepatocellular carcinoma (HCC) in chronic hepatitis B patients, their efficacy is far from completely satisfactory. The risk of liver cirrhosis and HCC begins to increase at an HBV DNA level of $10^4$ copies/ml. Even with latent or past HBV infection, episomal covalently closed circular DNA(cccDNA) plays a key rolein the persistence, relapse and resistance of HBV in its natural course or during therapy. The annual incidence of HCC in YUMC is 1.8% and 4.7% patients/year in the antiviral treatment and control groups, respectively. The ability to achieve a high rate of sustained HBV suppression with low risk of drug resistance is the ultimate goal in the treatment of chronic HBV infection. The efficacy of universal immunization with striking reductions in the prevalence of HBV in localized countries needs to be spread worldwide. With hepatitis B immunization and effective antiviral therapy, global control of HBV infection and HBV-related complications, including HCC, are possible by the end of the first half of the $21^{st}$ century.