• Journal of the Korean Society of Food Science and Nutrition
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• v.36 no.6
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• pp.720-726
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• 2007

This study was performed to investigate effects of raw sea tangle products on idiopathic constipation. A total of thirty-eight women participated voluntarily in this study. They were placed into one of four groups by their total colonic transit time (TCTT) to make the four groups have the same TCTT. In the first trial, the subjects in Control group were fed 3 times of 150 mL of mineral water per day for 2 weeks, those in +Control group were fed a kind of stool softener as well as the same mineral water for 3 times, those in STT group were fed 3 times of 150 mL of sea tangle tea and those in STB group were fed 3 times of 150 mL of sea tangle beverage. After 6 weeks, a second trial was performed for another 2 weeks. Although the TCTT of the group exposed to of KolomarkTM was not significantly reduced, the subjects in STT group answered that their evacuation activities were significantly improved; evacuation frequency was increased, stool hardness was reduced, evacuation straining was lessened, stool amount was increased, incomplete sense of evacuation was lessened, and major evacuation time was improved like those in +Control group. The results imply that it is worthy to develop some products of raw sea tangle such as STT, which are effective in treating or preventing constipation.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.13 no.5
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• pp.2267-2277
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• 2012

The purpose of this study was to evaluate the effects of 7 minutes a day, 3 times a week, for 4 weeks of abdominal meridian massage with aroma oils (AMMAO) by Volunteers on the relief of constipation among hospitalized disability patients with brain lesions. One group pretest-posttest quasi experimental research design was used. Subjects were 38 hospitalized disability patients with brain lesions. Data were collected from May 9 to June 19, 2011. Frequencies, mean, standard deviation and Repeated Measures ANOVA with SPSS 19.0 were used to evaluate the effects of AMMAO. The results were as follows; 1. There were significant difference noted in the amount of defecation(F=3.56, p=.033) by time. 2. There were no significant difference was noted in the frequency of defecation, the frequency of suppository or enema application by time. Accordingly, it is concluded that AMMAO would be an effective nursing intervention in relief of constipation among hospitalized disability patients with brain lesions. Therefore it is recommended that AMMAO be used in clinical practice as an effective nursing intervention for hospitalized disability patients with brain lesions.

• Journal of the Korean Academy of Child and Adolescent Psychiatry
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• v.12 no.2
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• pp.263-274
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• 2001

This article describes and illustrates cases the treatment of primary and secondary encopresis using a changing conditions and criterion design with two subjects. The dependent variables measured were increase in appropriate toileting behavior and decrease in inappropriate toileting behavior. After 12 and 13 weeks of treatment encopresis was completely eliminated. In a two-month follow-up and one year follow-up inappropriate toileting behavior was not reported. Appropriate toileting behavior was also reported generalized to settings outside the home.

• Journal of Industrial Convergence
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• v.21 no.2
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• pp.25-32
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• 2023

Constipation is the most common digestive disorder, and it occurs frequently in the early stages and affects the prognosis on rehabilitation stage in the patients with brain injury. The purpose of this study is to evaluate the bowel habits of brain-injured patients undergoing enteral nutrition immediately after admission to rehabilitation and transmission, and to investigate the effects of abdominal massage and lower extremity exercise. The study design is a quasi-experimental study to investigate the effect of a bowel care intervention (abdominal massage and lower extremity exercise) applicable to patients with brain lesions. As a result of the study, the number of bowel movements was significantly higher in the intervention group (p=.030), and the use of suppositories in the control group was statistically significantly higher than that in the intervention group (p=.004). The time of constipation relief was 1.73 days for the experimental group and 4.61 days for the control group, indicating that there was a difference in the time of constipation relief between the two groups (p<.001). Abdominal massage and lower extremity exercise were effective as nursing interventions to relieve constipation and prevent constipation in patients with brain injury from the early stage of rehabilitation.

• Journal of the Korean Society of Food Science and Nutrition
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• v.43 no.1
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• pp.55-59
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• 2014

This study investigated the improvement effects of fermented chicory fiber (FCF) on the intestinal function and constipation. The condition of fermentation was Bifidobacterium thermophilum added into chicory fiber (CF) flour suspension with the range of a 1% before incubation at $37^{\circ}C$ for 48 hr. The intestinal improvement effect of FCF was measured by the charcoal meal transit method in Balb/c mice. The intestinal transit with FCF at a dose of 1.62 mg/g was significantly increased to 88% compared with the CF group (P<0.01). Further, the constipation relief effect was investigated in Sprague-Dawley rats with loperamide-induced constipation. After oral administration of FCF 2.06 mg/g was remarkably decreased to 75% in fecal output compared with CF group (P<0.01). These findings indicated that FCF was more effective than CF for the intestinal function and constipation.

• Journal of the Korean Society of Food Science and Nutrition
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• v.32 no.4
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• pp.621-626
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• 2003

The aim of this study was to evaluate the effects of 40% sucrose replacement with oligosaccharides (fructo- orisomalto-) in sponge cakes. The 18 female college students were divided into two groups; fructooligosaccharide sponge cake group (FOS) and isomaltooligosaccharide sponge cake group (IMOS). In each group, the subjects received 50 g/d of sponge cake which contained about 8 g oligosaccharides for 2 weeks. The results were as follows: (1) Frequency of stool evacuation tended to increase after 1 week and significantly increased after 2 weeks in both groups. (2) Shape and color of stool did not change in FOS group but the IMOS group showed significant improvement. (3) The stool amounts per defecation were not significantly different in both groups. (4) The time of defecation decreased 50% after 1 week in FOS group and tended to decrease gradually in IMOS group. (5) Consistency of stool was significantly decreased after 1 week in both groups and continuously decreased until 2 weeks. (6) Effort for evacuation and comfort feeling after evacuation were significantly improved only in IMOS group after 2 weeks. (7) Gastrointestinal complaints concerning diarrhea, abdominal pains, nausea, flatulence, loss of appetite and weight and bloating were apparent. The symptoms such as abdominal pains, flatulence, and bloating in FOS group lasted for 2 weeks. However, the complaints appeared only during two or three days in IMOS group. In conclusion, our results suggest that isomaltooligosaccharide was more effective than fructooligosaccharide for preventing constipation because isomaltooligosaccharide worked safely in gastrointestinal lumen.

• Pediatric Gastroenterology, Hepatology & Nutrition
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• v.10 no.1
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• pp.51-59
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• 2007

Purpose: Recently well-developed anorectal function tests have revealed that there is an obvious pelvic floor dyssynergia (PFD) pattern in pediatric patients with constipation, as well as in adult's. The use of biofeedback therapy (BT) has been widely implemented in adult PFD patients; however, this approach has only rarely been considered for pediatric PFD patients. Therefore, we assessed the effectiveness of BT in children with PFD. Methods: We studied 70 children with PFD, who were referred to the department of pediatrics at the Asan Medical Center for the management of soiling or chronic constipation from September 2002 to February 2005. Diagnosis of PFD and assessment of the efficacy of BT for PFD treatment were carried out along with several ano-rectal function tests (cine-defecography, ano-rectal manometry, balloon expulsion test and intra-anal EMG); in addition, a questionnaire was administered. The BT based intra-anal EMG was performed. A follow-up telephone interview was performed more than 6 months later. Results: Most of the symptoms and results of the ano-rectal function tests were statistically improved after BT. In comparisons between the BT and control groups (BT refusal group due to poor compliance), the symptoms were statistically improved at follow-up. Therefore, for the shortterm improvement of symptoms, BT was better than conservative therapy alone. The negative feelings associated with ano-rectal function testing and BT were directly associated with failure or success of therapy. Conclusion: Pediatric patients with constipation or soiling that presented with an obvious PFD pattern showed that BT was a useful therapeutic tool for rapid improvement of symptoms.

• Clinical and Experimental Pediatrics
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• v.51 no.4
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• pp.391-395
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• 2008

Purpose : This study was performed evaluate optimal dose for disimpaction, efficacy and safety of PEG 4000 in children with chronic functional constipation. Methods : Eighty six children with chronic functional constipation were enrolled in this prospective study at Konkuk university hospital March, 2003 through August, 2006. Success in disimpaction with PEG 4000 was defined as meeting at least two out of three criteria; resolution of chief complaint, getting easiness of defecation with respect to frequency of bowel movement and hardness of stool based on defecation diary, and decrease in fecal impaction on simple abdominal X-ray test. Adverse effects of PEG 4000 were monitored clinically and biochemically. Results : Eighty three out of 86 children completed the study, and success rate of disimpaction was 99% (82/83). The mean dose of PEG 4000 for disimpaction was $0.93{\pm}0.28g/kg/day$ (0.4-2.0 g/kg/day, Max.: 30 g/day). Frequency of bowel movement increased ($5.02{\pm}2.71/wk$ vs. $11.25{\pm}5.43/wk$) in most children (79/83). Fecal impaction on simple abdominal X-ray test improved with statistical significance in 25 children (P=0.0007). Because of adverse effect of PEG 4000, 3 children did not complete the study; urticaria, severe diarrhea, diarrhea and abdominal pain. One 6-year-old girl who completed the study complained tingling sensation in the hand and foot without laboratory abnormality (4/86, 4.7%). Laboratory test revealed hyperosmolality without clinical symptom in 1 child, and eosinophilia in 6 children. Conclusion : The average safe and effective dose of PEG 4000 for disimpaction was $0.93{\pm}0.28g/kg/day$ (0.4-2.0 g/kg/day, Max : 30 g/day) in children with chronic functional constipation.

• Bulletin of Food Technology
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• v.15 no.2
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• pp.45-58
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• 2002

본 연구에서는 국내산 몰로키아 잎에서 추출한 mucilage의 이화학적 특성, 동물실험을 통한 콜레스테롤 대사에 미치는 영향가 임상실험에서의 비만 및 체지방대사에 미치는 영향을 검토하였다. 몰로키아 잎은 식이섬유의 함량이 37.4%, 단백질의 함량은 24.4%를 차지하고 있으며, 칼슘의 함량이 2,000mg% 이상으로 대단히 높았다. 몰로키아 앞에서 추출된 mucilage의 경우 단백질의 총당에 대한 비율이 $50^{\circ}C$에서 57.6%를 차지하였으며, 구성다당류의 분자량은 약 500,000 dalton의 크기를 나타내었고 40,000 dalton 이하의 것도 일부 존재하는 것으로 나타났다. 동물실험에서는 혈장의 총 콜레스테롤 함량은 대조구인 셀룰로오스 첨가군과 유의적인 차이가 나타나지 않았지만, 간에서의 지방 농도는 몰로키아 분말과 mucilage 첨가군이 유의적으로 감소되었고 변으로의 콜레스테롤 배설량도 몰로키아 분말 첨가군과 mucilage 첨가군 순으로 높았다. 몰로키아의 섭취가 다이어트와 변비개선에 미치는 효과를 검토한 결과, 체중의 감소는 아주 낮은 유의성을 보였고, 혈액 내 생화학적 수치에서 초기치와 8주 후의 값에는 유의한 차이를 보이지 않았지만, 체지방율의 경우에는 현저히 줄어들었다. 또한 몰로키아의 섭취로 배변이 2배 이상 증가하였으며, 배변시의 통증도 상당히 완화시키는 것으로 나타났다.

• Journal of Nutrition and Health
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• v.48 no.1
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• pp.19-29
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• 2015

Purpose: To investigate the effects of the intake of xylooligosaccharide-sugar mixture (XOS) on defecation frequency and symptoms in 56 young women (mean age of 22.1 years old) with constipation. Methods: Two experiments were conducted. In experiment 1, a randomized double-blind study was performed to evaluate the effect of 6 weeks' intake of 10 g sucrose containing 7% xylooligosaccharide or 10 g sucrose on constipation. In experiment 2, 24 g coffee mixture containing 12.8 g plant cream and 11.2 g xylooligosaccharide-sugar mixture was consumed by the subjects. During the study, the clinical efficacy was assessed by using a daily diary. The subjects indicated the number of frequencies they defecated in a day and the clinical symptom scores. Results: In experiment 1, the mean frequency of defecations was 2.07 in the pretreatment week and increased significantly to 4.05, 4.42, 4.84, 4.84, and 4.05 in weeks 2 to 6 of XOS intake, in comparison with the 3-3.67 with sucrose intake (sucrose, SUC). In experiment 2, the mean frequency of defecations significantly increased from 2.47 in the pretreatment week to 4.11-5.67 in weeks 1-6 of XOS intake. The occurrence of very loose or loose stools in the XOS group was significantly increased in weeks 5 and 6, compared with the pretreatment week and SUC group. XOS intake significantly alleviated the abdominal displeasure and feeling of residual stool leftness in weeks 2, 3, 5, and 6, while SUC did so in weeks 4 and 6 (p < 0.05). The coffee mixture containing xylooligosaccharide-sugar mixture reduced the abdominal displeasure and feeling of residual stool leftness from week 3 until the end of the experiment (p < 0.05). Conclusion: Our results suggest that xylooligosaccharide-sugar mixture intake was effective, without adverse effects, for the alleviation of constipation in the young women in this study.