• Journal of Radiation Protection and Research
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• v.25 no.1
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• pp.45-51
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• 2000

The purpose of this experiment is to investigate the retention of the radiomercury among the organs in mice. We used the healthy ICR male mice and divided into two grouos. The experimental group was orally treated with squalene(200mg/kg of body weight) at two times a day(12 hrs interval) and radiomercury(0.005 uCi/g of body weight.) only one time. The control group was treated only with radiomercury as same amount of the experimental group. As the result, main retentive organs were kidney, liver, blood, heart and skull. In the control group, all of these organs showed high retention of the radiomercury at 6 hours, but in the experimental groups, all the organs significantly inhibit retention of the .radiomercury by squalene(p<0.05). We conclude that squalene inhibit retention of the radiomercury.