• Title/Summary/Keyword: 방사선조사효과

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Commercial Utilization of Irradiation for the preservation of Foods and its Hygienic Effects (방사선조사에 의한 식품저장의 산업화 필요성과 위생적 효과)

  • 조한옥
    • Journal of Food Hygiene and Safety
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    • v.1 no.1
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    • pp.107-113
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    • 1986
  • It is estimated that the loss of Korean agricultural and fishery products during the storage period is usually more than 20%, and it is difficult to increase agricultural products by a 10% annual rate directly. Therefore, development of food preservation techniques has now become a most important atternative for the indirect increase of such products and for its senitary distribution. Changes eating habits and improved living conditions have accelerated the demand for convenience food production and for this reason it is essential that raw materials at stable, resonable prices and hygienic quality be available the year round. At the end of 1980, the Korean government conceded th economical feasibility of the storage of foods by irradiation and a procedure for preserving food by irradiation on a batch scale was successfully developed by KAERI in 1982. Based on the research results accomplished by the KAERI and on the recommendation on wholesomeness of irradiated food by Joint Committee of FAO/IAEA/WHO in 1980, the approval of wholesomeness of irradiated food was declared by presidential decree in June 1985 and the procedure of permission for individual items is in progress. Korean private firms (Ryung Young Co.) which was technically assisted by KAERI for five years have taken mush interest in the establishment of such facilities in Korea, therefore Ryung Young Co. had proposed for the construction of 500 Kci Co-60 irradiator to the Ministry of Science and Technology in July 1984. The permission of construction has approved by government in May 1985. The commercial irradiator will be constructed as one of the most modernized facilities until May 1987 and that facilities will contribute the propagation of commercial storage of foods and its hygienic quality.

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An effect of time gating threshold (TGT) on a delivered dose in internal organ with movement due to respiration (호흡에 의해 내부 움직임을 갖는 장기에 전달되는 선량에서 Time Gating Threshold(TGT)의 효과)

  • Kim, Yon-Lae;Chung, Jin-Bum;Suh, Tae-Suk
    • Proceedings of the Korean Society of Medical Physics Conference
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    • 2004.11a
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    • pp.132-135
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    • 2004
  • In this study, we investigated the effect of threshold on a delivered dose in organ with internal motion by respiration. With mathematic model for 3D dose calculation reported by Lujan et al., we had calculated the position of organ as a function of time in previous study. This result presented that the variation of organ is within 2 mm from initial exhale position to the organ position during operating 1 s. Gating threshold, in this study, is determined to the moving region of target during 1s at a primary position of exhale. This period of gating threshold is 50% of the duty cycle in a half breathing cycle which is period from the top position of exhalation to the bottom position of inhalation. Radiation fields were then delivered under three conditions; 1) existent of moving target in the region of threshold(1sec, 1.5sec), 2) existent of moving target out of the region of threshold, 3) non-moving target. The non-moving target delivery represents a dose different induced due to internal organ motion.

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방사선(放射線) 조사후(照射後)의 N:GP(S) mouse 비장세포(脾臟細胞) 증식(增殖)에 미치는 보중익기탕(補中益氣湯)과 사육탕(四六湯)의 효과

  • Lee, Neung-Gi;Choe, Seung-Hun
    • THE JOURNAL OF KOREAN ORIENTAL ONCOLOGY
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    • v.2 no.1
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    • pp.91-100
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    • 1996
  • Radiotherapy is an irreplaceable method of cancer treatment but, it has various side effects, especially damage to the hemopoietic system. A lot of radioprotectors have been found but they also have toxic effects. Many kinds of crude drugs(Oriental Chinese medicine)with low toxicity have been reported to promote the recovery from radiation damage. Recently, the trial to combine radiotherapy with herbal treatment of cancer patients shows a desirable result, an enhancement in recovery of the blood system.. This study was performed to determine whether prescriptions to support the healthy energy and strengthen the body resistence, Buzhongyiqi-tang and Siliu-tang, promote the recovery of splenocytes of N:GP(s) mice from radiation damage. We investigated the proliferative effect of Buzhongyiqi-tang, Siliu-tang and EIB(ethanol insoluble fraction of Buzhongyiqi-tang) on N:GP(S)mice splenocytes before or after ${\gamma}$-irradiation. We also investigated the morphology of splenocytes cultured with these herbs. Buzhongyiqi-tang and Siliu-tang promoted the proliferation of splenocytes in a concentration of 0.1 mg/ml compared with normal control(p<0.001). After 1-5Gy of ${\gamma}$-irradiation they also showed the effect of recovery of hemopoietic cells, especially in Buzhongyiqi-tang(4Gy:p<0.005; 5Gy:p<0.05). In addition, EIB(ethanol insoluble fraction of Buzhongyiqi-tang) showed the highest proliferative effect of all agents suggesting that more effective fractions could be found from crude herbs or prescriptions. These results suggest that it is possible to make use of Buzhongyiqi-tang, Siliu-tang or EIB as radio-protective agents.

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The effect of Phyllostachys nigra var. henenis Strapf leaf extract in the gamma-irradiated mice (방사선 조사 마우스에서 분죽(Phyllostachys nigra var. henenis Strapf)잎 추출물의 효과)

  • Shin, Dong-Ho;Kim, Jong-Choon;Kim, Se-Ra;Oh, Heon;Park, In-Chul;Oh, Ki-Seok;Chung, Hee-Jong;Jang, Jong-Sik;Kim, Sung-Ho
    • Korean Journal of Veterinary Research
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    • v.43 no.1
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    • pp.49-55
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    • 2003
  • This study was performed to determine the effect of Phyllostachys nigra var. henenis Strapf leaf extract on jejunal crypt survival, endogenous spleen colony formation and apoptosis in jejunal crypt cells of mice irradiated with high and low dose of gamma-radiation. Phyllostachys nigra var. henenis Strapf administration before irradiation (I.P.: 125 mg/kg of body weight, at 24 hours before irradiation) resulted in an increase of the formation of endogenous spleen colony (p<0.01). The frequency of radiation-induced apoptosis was also reduced by pretreatment of Phyllostachys nigra var. henenis Strapf (I.P.: 280 mg/kg or 28 mg/kg of body weight, at 24 hours before irradiation, p<0.01). These results indicated that Phyllostachys nigra var. henenis Strapf might be a useful radioprotector, especially since it is a relatively nontoxic natural product. Further studies are needed to characterize better the promotion nature of Phyllostachys nigra var. henenis Strapf and its components.

Comparison of computer-based treatment prediction with true results in bimaxillary protrusion cases (치조성 양악 전돌 환자에서 컴퓨터를 이용한 치료 결과 예측의 정확성)

  • Lee, Rhi-na;Lim, Yong-Kyu;Lee, Dong-Yul
    • The korean journal of orthodontics
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    • v.32 no.3 s.92
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    • pp.155-163
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    • 2002
  • This study was performed to assess the accuracy of computer-based treatment prediction for soft tissue profile using Quick Ceph Image $Pro^{TM}\;&\;Quick\;Ceph\;2000^{TM}$ in bimaxillary protrusion cases. The Ore- and post-treatment lateral cephalograms of 21 female adults treated by low first premolar extraction were imaged and 9 landmarks and 27 specific soft tissue mesurements were digitized for comparing actual treatment results with computer simulations. The results of this study showed that Quick Ceph Image $Pro^{TM}\;&\;Quick\;Ceph\;2000^{TM}$ tends to overestimeate horizontal changes and underestimate vertical changes. In the computer simulation, upper lip showed rolling tendency. The upper lip measurements were disposed to be regular direction hut lower lip measurements were varied case by case even if it was statistically insignificant.

Experimental Effects of Acanthopanax sessiliflorus $S_{EEM}$ Extracts Following Gamma-ray Irradiation on Immuno-stimulating and anti-tumor activity in mice (방사선(放射線)이 조사(照射)된 오갈피 나무의 추출물(抽出物)이 면역기능(免役機能) 및 항암(抗癌) 기능(機能)에 미치는 실험적(實驗的) 효과(效果))

  • Kim, Hyung-Woo;Han, Jin-Geun;Kim, Geo-Woong;Go, Hong-Gae;Jeong, Hyun-Woo;Cho, Su-In
    • The Korea Journal of Herbology
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    • v.22 no.1
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    • pp.63-70
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    • 2007
  • Objectives : This experimental study was designed to investigate the effects of Acanthopanax, sessiliflorus SEEM extracts following gamma-ray irradiation on immuno-stimulating and anti-tumor activity in terms of proliferation of tumor cells, thymocytes, splenocytes, and NO production from peritoneal macrophages in mice. Methods: 10AS and 100 AS were the bark powders of Acanthopanax sessiliflorus $S_{EEM}$ stems which were exposed in 10 kGy or 100 kGy of electron beam respectively. Results : Treatment with either 10AS or 100AS increased proliferation rates of thymocytes and splenocytes significantly, and treatment with l0AS also decreased proliferation rates of tumor cells significantly. Treatment with either l0AS or l00AS promoted NO production from peritoneal macrophages significantly. Conclusion : These results suggested that AS has direct inhibition effect of tumor growth and immuno-stimulating activity. In conclusion, we demonstrate that AS could be used to treat cancer patient as complementary or alternative medicine to typical anti-cancer medication.

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The Korean Public Understanding of Irradiated Food (방사선조사 식품의 국민이해 연구 - '인상(impression)'의 차이와 정보제공효과를 중심으로 -)

  • Park, Sung-Chol;Kim, Hak-Soo
    • Journal of the Korean Society of Food Culture
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    • v.16 no.1
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    • pp.1-12
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    • 2001
  • The main purposes of this study are to know the contents and forms of impressions that the general public, and the consumerists and environmentalists have of irradiated food, and to know what information of irradiated food influences their impressions. Other purposes are to know what sources those impressions derive from, to know which media they have recently been exposed to and paid attention to irradiated food through, to know which sources they trust of information regarding irradiated food most greatly, and finally to suggest policies and strategies of communication in order to shed positive impressions of irradiated food on people. This study was conducted through the person-to-person interview survey toward 1,200 adults, and 150 consumerists and environmentalists in 1999. Adults are sampled nationally in South Korea. Only 8.7% of the general public have heard of irradiated food. Impressions of irradiated food that the general public mentioned most frequently are: harmful, insecure, negative, etc. The consumerists and environmentalists were found to have the most inaccurate knowledge of irradiated food. Television and newspaper were the major sources of impressions of, exposure to and focus of attention on irradiated food. Based on these results, we seem to devise methods to enhance impression of irradiated food by disseminating information of advantages and benefits that irradiation provides food with and to promote the fact that irradiation on food is totally irrelevant to being radioactive, danger of a nuclear power plant, genetically modifying food, etc.

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Effect of Red Ginseng on Radiation-induced Learning and Memory Impairment in Mouse (방사선 조사 마우스에서 학습기억 장애에 대한 홍삼의 효과)

  • Lee, Hae-June;Kim, Joong-Sun;Moon, Chang-Jong;Kim, Jong-Choon;Jo, Sung-Kee;Jang, Jong-Sik;Kim, Sung-Ho
    • Journal of Ginseng Research
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    • v.33 no.2
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    • pp.132-138
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    • 2009
  • Previous studies suggest that even low-dose irradiation can lead to progressive cognitive decline and memory deficits, which implicates, in part, hippocampal dysfunction in both humans and experimental animals. In this study, whether red ginseng (RG) could attenuate memory impairment was investigated through a passive-avoidance and object recognition memory test, as well as the suppression of hippocampal neurogenesis, using the TUNEL assay and immunohistochemical detection with markers of neurogenesis (Ki-67 and doublecortin (DCX)) in adult mice treated with a relatively low-dose exposure to gamma radiation (0.5 or 2.0 Gy). RG was administered intraperitonially at a dosage of 50 mg/kg of body weight, at 36 and 12 h pre-irradiation and at 30 minutes post-irradiation, or orally at a dosage of 250 mg! kg of body weight/day for seven days before autopsy. In the passive-avoidance and object recognition memory test, the mice that were trained for one day after acute irradiation (2 Gy) showed significant memory deficits compared with the sham controls. The number of TUNEL-positive apoptotic nuclei in the dentate gyrus (DG) was increased 12 h after irradiation. In addition, the number of Ki-67- and DCX-positive cells was significantly decreased. RG treatment prior to irradiation attenuated the memory defect and blocked apoptotic death as well as a decrease in the Ki-67- and DCX-positive cells. RG may attenuate memory defect in a relatively low-dose exposure to radiation in adult mice, possibly by inhibiting the detrimental effect of irradiation on hippocampal neurogenesis.

Studies on the Mutation Breeding of Naked Barley I. A New Mutant Variety "Radiation No. 6" and Several Promising Mutant Lines by Radiation (쌀보리의 돌연변이육종에 관한 연구 I. 방사선에 의한 유용변이계통 및 신품종 ′방사6호′에 대하여)

  • Kim, Y.S.;Park, K.Y.;Lee, D.K.;Kim, I.H.
    • KOREAN JOURNAL OF CROP SCIENCE
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    • v.21 no.1
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    • pp.82-86
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    • 1976
  • 'Radiation No. 6' the first mutant variety of naked barley in Korea was developed from Bangju as .a mother variety. The new variety was characterized by early maturity, short-culm and stablized high yield by the increased number of spikes. 'Radiation No. 6' was registered as a leading variety in 1974, .after 7 years since induction of mutation started.of mutation started.

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Comparison of Dosimetric Parameters of Patient with Large and Pendulous Breast Receiving Breast Radiotherapy in the Prone versus Supine Position (유방 크기가 큰 유방암 환자의 방사선 치료 시 환자의 자세에 따른 선량 비교)

  • Moon, Sun Young;Yoon, Myonggeun;Chung, Weon Kuu;Chung, Mijoo;Shin, Dong Oh;Kim, Dong Wook
    • Progress in Medical Physics
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    • v.26 no.4
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    • pp.234-240
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    • 2015
  • The purpose of this study is to analyze dosimetric parameters of patient with large and pendulous breast receiving breast radiotherapy in the prone versus supine position. The patient underwent computed tomography simulation in both prone and supine position. The homogeneity index (HI), conformity index (CI), coverage index (CVI) to the left breast as planning target volume (PTV) and the doses to the lung, heart, and right breast as organ at risk (OAR) were compared by using dose-volume histogram. The lifetime attributable risk (LAR) according to the prone and supine position was measured for the lung and right breast. The HI, CI of the PTV decreased 21.7%, 6.49%, respectively and the CVI increased 10.8% with the prone position. The mean and maximum dose to the left lung decreased 91.6%, 87.0%, respectively and the volume parameters also decreased over 99% with the prone position. The parameters to the right lung were same regardless of the position. The mean and maximum dose to the heart decreased 51.6%, 14.2% with the prone position. But the mean and maximum dose to the right breast increased unlike the other OARs. The LARs to the lung decreased 80.3% (left), 24.2% (right) but the LAR to the right breast doubled with the prone position. The prone position is a favorable alternative for irradiation of breast in patients with large and pendulous breasts.