• Title/Summary/Keyword: 방사선요오드 치료

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The Role of Adjuvant Postoperative External Beam Radiotherapy for Locoregional Control in Recurrent Advanced Papillary Thyroid Carcinoma : Preliminary Report in a Single Institute (재발된 진행 갑상선 유두암의 국소 및 부위 치료를 위한 수술후 보조 외부방사선의 역할)

  • Park, Sung Ho;Lee, Guk Haeng;Lee, Byeong Cheol;Lee, Myung Chul;Choi, Ik Joon
    • Korean Journal of Head & Neck Oncology
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    • v.31 no.2
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    • pp.29-35
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    • 2015
  • 목적 : 국소 재발한 진행된 갑상선 유두암의 치료로 수술 후 외부방사선의 역할을 알아보고자 하였다. 대상 및 방법 : 원자력병원에서 2000년 1월부터 2012년 2월까지 사이버나이프 혹은 외부방사선 치료를 받은 수술과 방사선요오드 치료 후 국소 재발한 진행된 갑상선 유두암 환자 13 명을 대상으로 하였다. 경과관찰 기간 동안 국소 및 부위 재발이 발생환 환자는 6 명이었다. 몇몇의 위험인자를 찾기 위해서 Kaplan-Meier method와 log-rank test를 이용하여 성별, 종양단계, 방사선 치료 전 수술 횟수, 방사선요오드치료 횟수, 수술 후 잔존 암의 여부, 원격전이에 대해 단변량 분석하였다. 결과 : 방사선 치료 후 평균 추적관찰기관은 53.8개월(범위, 36 ~ 108개월)이고 그중 남자는 4 명이었다. 1년, 2년의 무진행 생존률은 각각 76.9와 53.8%였다. 단병량 분석은 성별과 잔존 암여부(p = 0.0475 and p = 0.0475, 각각)에 따라 무진행 생존률이 진행한 그룹과 진행하지 않은 그룹 사이에 유의한 차이가 있다는 것을 보여줬다. 결론 : 외부 방사선 치료 전에 잔존 암이 없었던 환자의 100%에서 국소 및 부위 재발이 일어나지 않았다. 외부방사선 치료는 수술과 방사선요오드 치료에 반응하지 않는 환자 중 수술 후 잔존 암이 없는 경우에 효과적인 치료 방법이 될 수 있다.

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Comparison of the Measured Radiation Dose-rate by the Ionization Chamber and GM(Geiger-Müller) Counter After Radioactive Iodine Therapy in Differentiated Thyroid Cancer Patients (분화성 갑상선암환자의 방사성 요오드 치료시 전리함과 Geiger-Muller계수관에서 방사선량률 측정값 비교)

  • Park, Kwang-hun;Kim, Kgu-hwan
    • Journal of radiological science and technology
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    • v.39 no.4
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    • pp.565-570
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    • 2016
  • Radioactive iodine($^{131}I$) treatment reduces recurrence and increases survival in patients with differentiated thyroid cancer. However, it is important in terms of radiation safety management to measure the radiation dose rate generated from the patient because the radiation emitted from the patient may cause the exposure. Research methods, it measured radiation dose-rate according to the elapsed time from 1 m from the upper abdomen of the patient by intake of radioactive iodine. Directly comparing the changes over time, high dose rate sensitivity and efficiency is statistically significant, and higher chamber than GM counter(p<0.05). Low dose rate sensitivity and efficiency in the chamber had lower levels than gm counter, but not statistically significant(p>0.05). In this study confirmed the characteristics of calibrated ionization chamber and GM counter according to the radiation intensity during high-dose radioactive iodine therapy by measuring the accurate and rapid radiation dose rate to the patient explains, discharged patients will be reduced to worry about radiation hazard of family and others person.

Self-care, Self-efficacy and Social Support of Patients Receiving Radioactive Iodine Therapy (방사성요오드 치료 환자의 자가간호와 자기효능감 및 사회적지지)

  • Kim, Ji-Sook;Kim, Ji-Soo
    • The Journal of the Korea Contents Association
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    • v.13 no.11
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    • pp.261-268
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    • 2013
  • This study presents a descriptive research on the degree of self-care related to the prevention of radiation exposure after radioactive iodine therapy and on the relations between self-efficacy and social support to propose nursing interventions required for patients after radioactive iodine therapy. The research period lasted from March to May, 2013. The subjects included 108 patients that were receiving radioactive iodine therapy after thyroidectomy at a cancer hospital in Gyeonggi Province. The subjects scored mean 52.10 on self-care out of full 56 and as for the general characteristics of the subjects, there were significant differences in their self-care according to whether they had a child or not(t=-2.312, p=.023) and interest in health(t=5.689, p<.001). There were significant positive correlations between their self-care and their self-efficacy(r=.610, p<.001), family support(r=.646, p<.001), and medical staff support(r=.276, p=.004). Interest in health(t=5.301, p<.001) was predictor on level 1 of hierarchical regression and interest in health(t=2.140, p=.035) and family support(t=3.353, p=.001) turned out to influence the self-care of the subjects, recording total 46.3% explanatory power. The most important predictor was interest in health(${\beta}$=1.309, p=.035) of self-care.

The Feasibility Study of photoconductor materials for the use of a dosimeter in Radiotherapy (광도전체 물질의 치료 방사선 선량계 적용을 위한 가능성 연구)

  • Jang, Giwon;Shin, Jungwook;Oh, Kyungmin;Park, Sungkwang;Kim, Jinyoung;Park, Jikoon;Nam, Sanghee
    • Journal of the Korean Society of Radiology
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    • v.7 no.1
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    • pp.81-84
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    • 2013
  • The use of the dosimetry have been increasingly recognized as high radiation energy and radiation treatment planning(RTP) have rapidly developed in radiotherapy. There are many types of detectors for the dosimetry such as ionization chamber, film, TLD, diode, and etc. Among such detectors, the diode detector uses a photoconductor materials that generate electrical signals by the incident radiation energy. Though many research groups are recently interested in such materials, there is few experimental results except for silicon in the radiation therapy field. In this study, the feasibility of photoconductor materials was verified as a dosimeter through the evaluation of response properties at a high radiation energy. For the fabricated detectors based on $HgI_2$ and $PbI_2$, reproducibility, linearity, and pulse-rate response were analyzed. Such evaluations are essential factors for the use of dosimeter. From results, linearity and reproducibility of the fabricated $HgI_2$ detector indicated about 7% error. The fabricated $PbI_2$ detector showed 1.7% error in linearity, and 12.2% error in reproducibility.

Radiation Shielding to Minimize Image Information Loss (영상 정보 손실을 최소화하는 방사선 차폐체 연구)

  • Su-han Jang;Sang-Hyeun Park;Myeong-Sik Ju
    • Journal of the Korean Society of Radiology
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    • v.17 no.3
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    • pp.449-457
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    • 2023
  • Shielding for reducing exposure dose can make the diagnosis limited. The purpose of this study is to increase the efficiency of radiation protection and minimize the loss of image information by producing the shielding made of the water and the contrast medium which has different proportion and finding out the ideal proportion of them. Each shielding materials were made of water and water-soluble iodine contrast medium with the different proportion. The attenuation rate of absorbed dose was evaluated by the shielding materials in the plastic contents for measuring the efficiency of the radiation protection. As a result, the higher ratio of the contrast medium, the more efficient it is for radiation attenuation. The anatomical structure was observed most properly in case of the solution with 20 ml of the contrast medium and most difficultly in case of more than 60 ml of the contrast medium. In case of the signal intensity between skeleton and gas, the difference of average value had a significant as p < 0.001. Shielding with contrast medium attenuates less than the conventional shielding but in the examination for the sensitive part to radiation, it can be used to minimize the loss of the image information and reduce the exposure dose.

The Evaluation and Fabrication of Photoconductor Sensor for Quality Assurance of Radiation Therapy Devices (방사선치료기기 정도관리를 위한 광도전체 센서 제작 및 평가)

  • Kang, Sang Sik;Noh, Sung Jin;Jung, Bong Jae;Noh, Ci Chul;Park, Ji Koon
    • Journal of the Korean Society of Radiology
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    • v.10 no.8
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    • pp.565-569
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    • 2016
  • Recently, a use of linear accelerator with a multi-leaf collimator(MLC) for radiation therapy is increasing. The importance of quality assurance (QA) for the linear accelerator is emphasized as the side effects of the inaccurate delivery of the radiation beam has been increased according to the high dose irradiation technique. In this study, The $HgI_2$ and $PbI_2$ photoconductor layer samples of $400{\mu}m$ thickness were fabricated using sedimentation method among particle-in-binder technology. From the fabricated samples, the electrical properties(dark current, output current, response properties and linearity) were investigated. From the experimental results, $HgI_2$ has good charge signal generation and linearity. Finally, from the signal response results about various thickness of $HgI_2$ sensor, the signal creation efficiency of $400{\mu}m$ thickness of $HgI_2$ sensor has the highest value and the excellent reproducibility below ${\pm}2.5%$.

Feasibility Study of Phosphor Particle Blended Hybrid Dosimeter for Quality Assurance in Radiation Therapy (Phosphor Particle 혼합형 Hybrid 선량계의 방사선치료 Quality Assurance에 대한 적용가능성 평가)

  • Shin, Yohan;Han, Moojae;Jung, Jaehoon;Cho, Heunglae;Park, Sungkwang
    • Journal of the Korean Society of Radiology
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    • v.13 no.3
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    • pp.333-338
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    • 2019
  • In the field of radiotherapy, the Quality Assurance(QA) procedure to verify the safety of treatment is considered to be very important. However, due to various problems of the conventional dosimeters used for the QA, researches on these dosimeters have been actively carried out to replace them. In this study, to maximize the sensitivity by visible light(VL) emitted from phosphors, blended hybrid sensors were fabricated by blending various weight percent(wt%) of $Gd_2O_2S:Tb$ which is a phosphor with excellent fluorescence efficiency into $PbI_2$. Then, the electrical properties to high energy radiation from the blended sensors and the pure $PbI_2$ sensor were compared and evaluated. As a result of the sensitivity evaluation, the sensor of 3wt% showed the highest value with more than 40% difference from the other sensors, and gradual decreasing in sensitivity was observed with increasing wt% except for the sensor of 3wt%. Also, in the reproducibility evaluation, the pure $PbI_2$ sensor exhibited a large variation in coefficient of variation(CV)>0.015, while all the blended sensors showed CV<0.015.

The Evaluation on Reuse Period of Patient's Clothes and Sheet After Radioiodine Therapy (방사성 요오드 치료환자의 환의 및 시트에 대한 재사용주기 평가)

  • Kim, Yeong Seon;Seo, Myung Deok;Lee, Wan Kyu;Kim, Ki Joon;Song, Jae Beom
    • The Korean Journal of Nuclear Medicine Technology
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    • v.16 no.2
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    • pp.12-17
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    • 2012
  • Purpose : The patient's clothes and sheet after radioiodine therapy must be disposed of by related regulation. That must be disposed of as radioactive wastes, but that is reusing after radioactivity decay by keeping for the certain period of time. In general, The minimum storage period calculate by standard of take radioactive substance out of radiation controlled area based on measured surface contamination level. But the measurements of surface contamination level are able to differ by measurement method. In this paper, I wish to calculate the minimum storage period of patient's clothes and sheet after radioiodine therapy by measure nuclide concentration offered by the regulation on self-disposal of radioactive wastes. Materials and Methods : The whole area of patient's clothes and sheet measured 31 patients(male:9 patients, female:22 patients), who had radioiodine therapy(3.7 GBq:13 patients, 5.55 GBq:16 patients, 7.4 GBq:2 patients) from july 2011 to march 2012. The minimum storage period is calculated by the regulation on self-disposal of radioactive waste(100 Bq/g) and standard of take radioactive substance out of radiation controlled area(4 kBq/m2) Results : The minimum storage period of pillow sheet, upper uniform, lower uniform by standard of take radioactive substance out of radiation controlled area were each 4.6 days, 63days, 78 days. The minimum storage period of pillow sheet, upper uniform, lower uniform by the regulation on self-disposal of radioactive waste were each 18.1 days, 43 days, 62 days. Conclusion : We can verify that patient's clothes and sheet after radioiodine therapy exists a great deal of radioactive contamination. The minimum storage period calculation of patient's clothes and sheet is better suited to applying nuclide concentration offered by the regulation on self-disposal of radioactive waste. I recommend, To keep for at least 2 months of the patient's clothes and sheet contaminated radioactivity, for prevent contamination and unnecessary radiation exposure.

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Evaluation of Absorbed Dose According to the Nanoparticle in Prostate Cancer Brachytherapy (전립선암의 근접치료 시 나노입자에 따른 흡수선량평가)

  • Park, Eun-tae;Lee, Deuk-hee;Im, In-chul
    • Journal of the Korean Society of Radiology
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    • v.12 no.2
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    • pp.167-172
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    • 2018
  • This study evaluated absorbed dose of brachytherapy according to the nanoparticle in prostate cancer which many occurred in Korean man and provided basic data. Absorbed dose evaluation was using MCNPX program which was applied Monte Carlo simulation. Source was applied $^{192}Ir$ which was many using in Korean HDR machine and gold, ferric oxide, gadolinium and iodine nanoparticle were applied. Prostate absorbed dose result was increased when using nanoparticle, in particular gold nanoparticle was the highest result as $3.13E-03J/kg{\cdot}e$. Absorbed dose of surrounding organs and distance was similar between using nanoparticle and non-using nanoparticle. Therefore, brachytherapy was used nanoparticle was increased therapeutic ratio and efficiency of radiation therapy.