• Title/Summary/Keyword: 발병 위험도

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Optimal Waist Circumference for the Prevention of Cardiovascular Disease (심혈관계질환의 발병 위험을 선별할 수 있는 적정 허리둘레의 임계점)

  • Baik, In-Kyung;Shin, Chol
    • Korean Journal of Community Nutrition
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    • v.15 no.2
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    • pp.275-283
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    • 2010
  • There are few studies reporting optimal waist circumference that can be utilized to prevent the incidence of cardiovascular disease (CVD). We evaluated the association of waist circumference and waist and hip circumference ratio (WHR) with incident cases of CVD developed over 6 years in a population-based prospective study including Korean adults. Analyses for receiver-operating characteristic (ROC) curve were performed with data for 1,733 men and 1,579 women who were aged 40 to 69 years and were free of a physician-diagnosis of CVD at baseline. Information on the diagnosis of CVD was periodically reported using interviewer-administered questionnaires and anthropometric measures were obtained by biennial health examinations. We newly identified 77 cases of CVD during a follow-up period between 2003 and 2008. On the basis of measures of diagnostic accuracy including minimum distance to ROC curve and Youden index, waist circumference of 85 cm for men, in particular for male nonsmokers, and of 80 cm for women and WHR of 0.88 to 0.90 for men and of 0.83 for women were found to be optimal cutoff points to identify individuals at CVD risks. The study also found that the use of the suggested optimal values for waist circumference show higher sensitivity and lower specificity compared with 90 cm for men and 85 cm for women, which are waist cutoff points given by the Korean Society for the Study of Obesity to define abdominal obesity for Korean adults. Although lower cutoff points of waist circumference (83 cm) and WHR (0.87) were observed to be optimal for male smokers compared with male nonsmokers, whether suggesting waist cutoff points specific to smokers is needed warrants further studies. After taking into account other cardiovascular risk factors including smoking, men with waist circumference of 85 cm or greater and women with 80 cm or greater were at an increased risk of CVD. Thus, these cutoff points of waist circumference may be able to capture more individuals at CVD risks contributing to the prevention of future development of CVD.

Nomogram comparison conducted by logistic regression and naïve Bayesian classifier using type 2 diabetes mellitus (T2D) (제 2형 당뇨병을 이용한 로지스틱과 베이지안 노모그램 구축 및 비교)

  • Park, Jae-Cheol;Kim, Min-Ho;Lee, Jea-Young
    • The Korean Journal of Applied Statistics
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    • v.31 no.5
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    • pp.573-585
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    • 2018
  • In this study, we fit the logistic regression model and naïve Bayesian classifier model using 11 risk factors to predict the incidence rate probability for type 2 diabetes mellitus. We then introduce how to construct a nomogram that can help people visually understand it. We use data from the 2013-2015 Korean National Health and Nutrition Examination Survey (KNHANES). We take 3 interactions in the logistic regression model to improve the quality of the analysis and facilitate the application of the left-aligned method to the Bayesian nomogram. Finally, we compare the two nomograms and examine their utility. Then we verify the nomogram using the ROC curve.

A Pediatric Case of Dengue Fever with Extreme Hyperglycemia Developed in a Family Who Returned from India (인도에서 귀국한 가족에서 발생한 심한 고혈당 동반 소아 뎅기열 1례)

  • Kim, Joon Young;Kim, Han Wool
    • Pediatric Infection and Vaccine
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    • v.27 no.2
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    • pp.140-146
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    • 2020
  • Dengue fever (DF) is endemic throughout tropical and subtropical regions; however, it is not endemic in Korea. Imported infectious diseases should be suspected when encountering returned travelers with non-specific symptoms such as fever, rash, and headache. Persistent vomiting, abdominal pain, hemorrhagic tendency, hepatic enzyme abnormalities, and proteinuria are risk factors for the development of severe DF in a patient with DF. Severe hyperglycemia is also known to be related to poor prognosis in acute illness, and with certain underlying diseases that present with hyperglycemia, such as diabetes, it is related to the progression of severe DF. We report a DF case with severe hyperglycemia in an adolescent returning from India. Pediatric DF cases reported in Korea were also reviewed.

Incidence and Risk Factors of Pulmonary Thromboembolism in Pedicled TRAM Breast Reconstruction (유경횡복직근피판을 이용한 유방복원술시 폐색전증의 발병률과 위험인자)

  • Lee, Sang Hyuk;Lee, Taik Jong;Eom, Jin Sup;Son, Byung Ho;Ahn, Sei Hyun;Lee, Sang Do
    • Archives of Plastic Surgery
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    • v.33 no.2
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    • pp.193-197
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    • 2006
  • Pulmonary thromboembolism is often clinically silent and difficult to diagnose, and can be fatal to patients with belated treatment. This complication is seen in patients who underwent TRAM breast reconstruction. Multiple factors are involved in this disease such as the presence of malignancy itself, major surgery and therapy-related interventions. TRAM surgery is a lengthy procedure involving mastectomy, flap surgery and abdominoplasty. The purpose of this study is to evaluate the incidence and the correlation between presurgical risk factors(BMI and age) of symptomatic pulmonary thromboembolism after TRAM surgery and the incidence. From July 2001 to March 2005 a total of 384 pedicled TRAM reconstruction of breast was performed in 382 patients at Asan Medical Center. The average of Body mass index was $21.9kg/m^2$ and mean age of the patients was 37.9 years old. We diagnosed symptomatic pulmonary thromboembolism using ventilation/perfusion lung scan and pulmonary embolism computed tomography. Incidence of in-hospital symptomatic pulmonary thromboembolism was 1.3%. BMI and age showed no significant statistical relationship to pulmonary thromboembolism. But the incidence of symptomatic pulmonary thromboembolism in obese patients (BMI > 25) was 3.75%. According to the guideline of the 7th American College of Chest Physicians Consensus Conference on Antithrombotic and Thrombolytic Therapy, the incidence of 3.75% was classified as high risk group. The prevention of pulmonary thromboembolism should be considered in cases of obese patients with low molecular weight heparin(BMI > 25).

A Case of Pneumocystis carinii Pneumonia in an Infant with Failure to Thrive (성장 장애를 보인 영아에서 발현된 주폐포자충 폐렴 1례)

  • Kong, Sun Hui;Lee, Ho Jun;Kim, Soo Yeon;Kim, Hak Sung;Lee, Dong Woo;Kim, Jae Yoon
    • Pediatric Infection and Vaccine
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    • v.12 no.1
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    • pp.95-99
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    • 2005
  • Pneumocystis carinii pneumonia is an infectious disease which is highly prevalent in the group of immunosuppressed patients, particularly with hematologic tumors as lymphomas and acquired immune deficiency syndrome(AIDS), severe malnutrition, organ transplantations, high dose corticosteroid therapy. Some cases of Pneumocystis carinii pneumonia in infants with primary immune deficiency were already reported. The authors present a case of Pneumocystis carinii pneumonia developed in an infant who suffered from 10 days of poor feeding and failure to thrive and not included in the risk groups listed above. He had bilateral interstitial infiltrations on the chest radiography, diagnosed as Pneumocystis carinii pneumonia after Gomori-methenamine silver staining of his sputum that was taken through tracheal intubation. He improved after administering Trimethoprim-sulfamethoxazole for 14 days.

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The Relationship between Metabolic Syndrome and Korean Cardiocerebrovascular Risk Assessment: for Male Researchers in a Workplace (대사증후군과 뇌심혈관질환 발병위험도 평가와의 연관성: 일개 사업장 남성 근로자를 대상으로)

  • Yoon, Jong-Wan;Yi, Kyung-Jin;Lee, Sang-Yun;Oh, Jang-Gyun
    • Journal of Preventive Medicine and Public Health
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    • v.40 no.5
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    • pp.397-403
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    • 2007
  • Objectives: The prevalence of metabolic syndrome has recently increased, Payments from the Korea Labor Welfare Corporation for compensation for mortality in workers caused by cardiovascular and cerebrovascular diseases have also increased in Korea in recent years. The association of metabolic syndrome and cardiocerebrovascular disease has been investigated by several researchers in recent studies, This study was conducted in an attempt to characterize the relationship between metabolic syndrome and Korean cardiocerebrovascular disease risk assessment, and to provide basic data to group health practices for the prevention of cardiocerebrovascular disease. Methods: Health examinations were previously conducted for 1526 male researchers at a private laboratory. The prevalence by age and the odds ratio of metabolic syndrome scores into the "cardiocerebrovascular risk group" (sum of low, intermediate, and high risk groups) of the Korean cardiocerebrovascular disease risk assessment were assessed, in an effort to elucidate the associations between metabolic syndrome and cardiocere brovascular disease risk assessment. Results: The prevalence of metabolic syndrome and inclusion in the cardiocerebrovascular risk group was 11,7% and 22.1% respectively. The severity of metabolic syndrome and cardiocerebrovascular risk assessment showed that individuals in their 40's and 50's were at higher risk than those in their 30's (p<0,001). The age-adjusted odds ratio of metabolic syndrome to cardiocere brovascular risk group inclusion was 5.6. Conclusions: An active prevention program for cardiocerebrovascular disease needs to begin in the 40's, as the prevalence of metabolic syndrome and the risk group of cardiocerebrovascular risk assessment peak in the 40's age group. The odds ratio between metabolic syndrome and the cardiocerebrovascular risk group was high, which indicates that metabolic syndrome scores should be utilized as guidelines during the consultation and behavioral modification program for the workplace prevention of cardiocerebrovascular diseases in group health practices.

The Design and Implement a Healthcare Alert App to Prevent Dementia (치매예방을 위한 헬스케어 알리미 앱 설계 및 구현)

  • Pi, SU-Young
    • Journal of Digital Convergence
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    • v.16 no.10
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    • pp.59-67
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    • 2018
  • There are not that many m-health related services limited to the elderly. Many of the elderly who are at risk of dementia are unfamiliar to smart devices, so it is required to design an user-customized App. Therefore, I design and embody a mobile voice alert integrated app, which enables voice input to increase the accessibility of the elderly, so as to prevent diseases caused by declined cognitive function such as dementia. I conducted interviews and questionnaire after having the students use the app in Lifelong Education Center in H region of Gyeongbuk, and the analysis result has showed the high satisfaction. It is expected that it will be able to play a key role for M-Health service for the elderly since it is possible to prevent dementia through the voice health care alert app. I would like to learn deep learning in the future to predict the life patterns and the possibility of dementia of the elderly.

Analysis of Lung Function Influences by Stimulating Ear Reflex Point Using Voice Analysis (음성 분석을 통한 폐 이혈점 자극이 폐 기능에 미치는 영향 분석)

  • Kim, Bong-Hyun;Cho, Dong-Uk
    • The Journal of Korean Institute of Communications and Information Sciences
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    • v.37 no.6C
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    • pp.520-526
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    • 2012
  • Mostly lung diseases by smoking and air pollution is increasing social interest one of 6 kinds of modern diseases which is difficult functional recovery of damaged lung as dangerous diseases of life extension. Therefore, to reduce suffering from respiratory diseases is usually non-smoking, to do strengthen behavior of lung function. In this paper, we would like to propose method to do investigation by voice analysis technology to apply when lung associated ear acupuncture point stimulus to help strengthen actually lung function. From this, we would like to consider the voice change of before/after in smoking to analyze the impact on the human body to the lungs. Based on this experiment, we would like to investigate numerically quantity data actual improved lung function to analyze of voice character difference of before/after in lung associated ear acupuncture point stimulating.

Voice Features Extraction of Lung Diseases Based on the Analysis of Speech Rates and Intensity (발화속도 및 강도 분석에 기반한 폐질환의 음성적 특징 추출)

  • Kim, Bong-Hyun;Cho, Dong-Uk
    • The KIPS Transactions:PartB
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    • v.16B no.6
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    • pp.471-478
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    • 2009
  • The lung diseases classifying as one of the six incurable diseases in modern days are caused mostly by smoking and air pollution. Such causes the lung function damages, and results in malfunction of the exchange of carbon dioxide and oxygen in an alveolus, which the interest is augment with risk diseases of life prolongation. With this in the paper, we proposed a diagnosis method of lung diseases by applying parameters of voice analysis aiming at the getting the voice feature extraction. Firstly, we sampled the voice data from patients and normal persons in the same age and sex, and made two sample groups from them. Also, we conducted an analysis by applying the various parameters of voice analysis through the collected voice data. The relational significance between the patient and normal groups can be evaluated in terms of speech rates and intensity as a part of analized parameters. In conclusion, the patient group has shown slower speech rates and bigger intensity than the normal group. With this, we propose the method of voice feature extraction for lung diseases.