• Title/Summary/Keyword: 발병지수

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Evaluation of Clinical Usefulness of Gamma Glutamyl Transferase as a Surrogate Marker for Metabolic Syndrome in Non Obese Adult Men (비만하지 않은 성인 남성에서 대사증후군의 대리 표지자로서 감마 글루타밀 전이효소의 임상적 유용성 평가)

  • Shin, Kyung-A;Kim, Eun Jae
    • Journal of Convergence for Information Technology
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    • v.10 no.12
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    • pp.146-155
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    • 2020
  • This study was to evaluate the usefulness of gamma glutamyl transferase (GGT) as a surrogate marker predicting metabolic syndrome. 7,155 non obese men over the age of 20 were studied as subjects. The criteria for diagnosing MetS were the National Cholesterol Education Program - Third Adult Treatment Panel (NCEP-ATP III). The risk of developing MetS according to GGT was conducted logistic regression analysis, and the ROC (receiver operating characteristic) curve was obtained to confirm GGT ability to predict the risk of MetS. Regardless of age and body mass index, MetS had a 7.09 times higher risk of onset in the fourth quartile than in the first quartile of GGT (p<0.001). The AUC (area under the curve) of GGT for the diagnosis of MetS was 0.715, and the cutoff value of GGT was 40.0 U/L, the sensitivity was 65.0%, and the specificity was 70.2%. Therefore, GGT is considered to be a useful diagnostic index for diagnosing MetS.

Analysis of the Factors Influencing the Efficiency of Natural Recreation Forest Management (자연휴양림 경영효율성에 대한 영향 요인 분석)

  • Seung Yeon Byun;Do-il Yoo;Ja-Choon Koo
    • Journal of Korean Society of Forest Science
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    • v.113 no.2
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    • pp.153-163
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    • 2024
  • Since the onset of the COVID-19 pandemic, there has been a significant shift in the lifestyle patterns of the populace across various domains. Concerns surrounding COVID-19 have emerged as pivotal catalysts of change in recreational habits with people giving a particular preference for environments with low population density and increased openness. This trend has resulted in an uptick in excursions to natural reserves, coastlines, and parks. However, during the peak of infectious outbreaks, widespread adherence to social distancing measures has precipitated a steep decline in tourist footfall across natural recreation forests, exacerbating financial deficits to a considerable extent. Thus, this research sought to compare and analyze the operational efficacy and productivity of national, public, and private natural recreation forests pre- and post-COVID-19 pandemic by utilizing non-parametric methodologies, such as data envelopment analysis and the Malmquist productivity index analysis. The objective was to identify the factors contributing to the decreases in efficiency and productivity and ultimately offer nuanced recommendations tailored to respective administrative bodies. This study's distinctive focus on the analysis of management efficiency and productivity in natural recreation forests nationwide offers significant academic and practical relevance.

Development of an Efficient In Vitro Screening Method for Selection of Resistant Lily Cultivars Against Fusarium oxysporum f. sp. lilii (백합 구근부패병 저항성 검정을 위한 기내 간편 검정법 개발)

  • Jang, Ji-Young;Moon, Ki-Beom;Ha, Jang-Ho;Park, Ji-Sun;Kim, Mi-Jin;Jeon, Jae-Heung;Lee, Geung-Joo;Kim, Hyun-Soon
    • Horticultural Science & Technology
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    • v.33 no.6
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    • pp.883-890
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    • 2015
  • The soilborne fungus Fusarium oxysporum f. sp. lilii (Fol) is a serious threat to all lily cultivars, especially infecting bulbs and flowers. It has become increasingly important to develop varieties resistant against the bulb rot disease. Genetic diversity of cultivars and reliable screening methods are required for this purpose. Here, an efficient in vitro screening system for evaluating resistance to Fol in 38 in vitro-grown lily plants was investigated. Various factors including culture conditions of Fol, inoculum density, appropriate plant materials, inoculation method and duration, and incubation period of plant materials after inoculation were combined to optimize the screening method. As a result, we suggest optimal conditions for an in vitro screening system for the selection of Fol-resistant lily cultivars as follows. Fol was grown on potato dextrose agar (PDA) medium for 6 days at $25^{\circ}C$ in darkness and used as working inoculation. Spore suspensions were prepared (inoculum density: $1.0{\times}10^4$ $spores{\cdot}mL^{-1}$), and then leaf segments $1.5{\times}2.0cm^2$ were inoculated by dipping for 22 hours at $25^{\circ}C$ in dark. Later, leaves were cultured on 0.6% agar plates at $25^{\circ}C$ and 50% humidity with a photoperiod of 16 hours light/8 hours dark (fluence rate of $40{\mu}mol{\cdot}m^{-2}{\cdot}s^{-1}$) to examine the progress of bulb rot. After 7 days, disease levels were classified into indices 1 (no symptom) to 6 (serious bulb rot). Soil inoculation of Fol carried out with resistant or susceptible lily cultivars that had been selected through in vitro screening confirmed the reproducibility of results. Therefore, the in vitro screening method established in this study is efficient and reliable for selection of lily cultivars resistant against bulb rot disease.

Pathogenicity of Two Species of Sclerotium to Nine Cultivars of Garlic Cultivated Widely in Korea (마늘의 흑색썩음균핵병에 대한 품종저항성의 역학적 평가)

  • Kim, Yong-Ki;Kwon, Mi-Kyung;Cho, Weon-Dae;Kim, Tack-Soo;Shim, Hong-Sik;Lee, Yong-Hwon;Lee, Chan-Jung;Lee, Seong-Chan
    • Research in Plant Disease
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    • v.10 no.2
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    • pp.105-111
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    • 2004
  • Mycelial growth and days required for sclerotial formation(DRSF) in vitro, and disease incidence of infected plants in the field were investigated to evaluate disease resistance of nine garlic cultivars against two species of Sclerotium causing garlic white rot. There were differences among mycelial growth and sclerotial formation of two white rot pathogens on different garlic cultivars in vitro. Mycelial growth showed the highest level on the clove of 'Daeseo'. Sclerotia of two white rot pathogen were formed the earliest on the clove of 'Kodang' and the latest on the clove of 'Namdo'. In field trial all of nine garlic cultivars were highly susceptible to Sclerotium cepivorum and cold-type garlics were less susceptible than warm-type garlics. Meanwhile garlic cultivars used showed differences among resistant responses to Sclerotium sp., forming large sclerotia. All of warm-type garlics showed highly susceptible response, but three cold-type garlics, 'Seosan', 'Danyang' and 'Yechon' showed moderate resistant response and 'Euisung' showed resistant response. To evaluate cultivar resistance of garlics quantitatively disease progress curve was transformed as linear regression equation. Among the intercept (early disease incidence) and the slope (disease infection rate) obtained from the transformed equation, final disease incidence, and area under disease progress curve(AUDPC), AUDPC was the most effective to evaluate disease resistance of garlics to both of white rot pathogens. There was little correlation between mycelial growth and sclerotial formation on garlic cloves in vitro, and epidemiological parameters (early disease incidence, final disease incidence, disease infection rate, AUDPC) obtained from the field trial. Mycelial growth of S. cepivorum was positively correlated with final disease incidence and disease infection rate obtained from the field trial, meanwhile DRSF was negatively correlated with the epidemiological parameters.

Effect of Sleep on Epileptiform Discharges in Epileptic Patients with Structural Lesion : Based on Routine EEG (기질적 뇌병변에 의한 간질환자에서 수면이 간질파의 발생에 미치는 영향 : 통상적 뇌파 분석)

  • Lee, Se-Jin;Hah, Jeong-Sang
    • Journal of Yeungnam Medical Science
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    • v.24 no.2
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    • pp.107-118
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    • 2007
  • Background : It is well known that non-rapid eye movement(NREM) sleep activates the occurrence of interictal epileptiform discharges(IED) in many epileptic syndromes. We performed this study to assess the effect of NREM sleep on IED in epileptic patients with organic brain lesions. Materials and Methods : We analyzed awake and sleep electroencephalopathy(EEG) recorded simultaneously after partial sleep deprivation in 50 patients. We calculated the awake and sleep spike index (ASI and SSI, spikes/epoch), and the percentage increase of ASI and SSI during sleep. Results : In the 50 patients, the IEDs were recorded exclusively during the awake state in 1 (2%) patient, and during the sleep state in 13(26%) patients. The SSI was higher in 44 (88%) patients, and the ASI was higher in 5 (10%) patients. The mean ASI and the SSI in patients with organic brain lesions were $0.058{\pm}0.121$ and $0.148{\pm}0.187$, and it was $0.081{\pm}0.150$ and $0.174{\pm}0.226$ in patients without organic brain lesions. There were significant increases in the spike index (P<0.05) during NREM sleep in both groups (n=36), but no significant difference in the percent increase of spike index (P>0.05). Conclusion : The IEDs were activated significantly during NREM sleep both in patients with and without organic brain lesions, but there were no differences in the degree of activation in both groups. The activating effect of NREM sleep was not correlated with clinical factors such as, frequent nocturnal seizures, frequent generalized tonic clonic seizures, type of epilepsy and taking anticonvulsants. We conclude that the routine EEG used to evaluate epileptiform discharges in epileptic patients should include sleep recordings after partial sleep deprivation.

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Comparison of the Usefulness of Lipid Ratio Indicators for Prediction of Metabolic Syndrome in the Elderly Aged 65 Years or Older (65세 이상 고령자에서 대사증후군 예측을 위한 지질비율 지표의 유용성 비교)

  • Shin, Kyung-A;Kim, Eun Jae
    • Journal of the Korea Convergence Society
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    • v.13 no.1
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    • pp.399-408
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    • 2022
  • The purpose of this study was to compare the usefulness of the lipid ratio indicators for the diagnosis of metabolic syndrome in the elderly aged 65 years or older. From January 2018 to December 2020, 1,464 people aged 65 years or older who underwent a health checkup at a general hospital in Seoul were included. Lipid ratio indicators were measured through blood tests. The prevalence of metabolic syndrome according to the quartiles of the lipid ratio index was confirmed by logistic regression analysis. In addition, the metabolic syndrome predictive ability and cutoff value of the lipid ratio indices were estimated with the receiver operating characteristic(ROC) curve. The correlation between atherogenic index of plasma(AIP) and waist circumference was the highest in both men and women(r=0.278, p<0.001 vs r=0.252, p<0.001). As for the lipid ratio indices, the incidence of metabolic syndrome was higher in the fourth quartile than in the first quartile. The area under the ROC curve(AUC) value of AIP was higher at 0.826(95% CI=0.799-0.850) and 0.852(95% CI=0.820-0.881) for men and women, respectively, compared to other lipid ratio indicators, and the optimal cutoff values for both men and women was 0.44(p<0.001). Therefore, the AIP among the lipid ratio indicators was found to be the most useful index for diagnosing metabolic syndrome in the elderly aged 65 years or older.

Studies on the Varietal resistance to the rice stripe virus disease (줄무늬잎마름병(호엽고병)에 대한 벼품종의 저항성에 관한 연구)

  • Lee S. H.;Kim C. H.
    • Korean journal of applied entomology
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    • v.5_6
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    • pp.47-54
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    • 1968
  • In order to develop an effective control measure for the rice stripe disease, methods of testing for resistance and selection of resistant varieties among the leading varieties were investigated. For use as a parent in breeding for resistant variety to the disease, total of 410 rice varieties were tested. 1. Disease occurrence was higher at group inoculation than that of individual inoculation in comparing the inoculation methods. 2. In both methods, Lacrose responded susceptible; Zenith and St. No. 1 resistant, and the rest moderate. 3. Suseptible symptom type A was prevalant among the susceptible varieties, while resistant symptom type C was abundant among the resistant varieties, There was no difference between the inoculation methods. 4. 410 rice varieties tested could he divided into 3 groups as susceptible (21 varieties), moderate (377 varieties) and resistant (12 varieties). Resistant varieties wers St. No. 1 and 2, Shin-2, Gulfrose Bonnet, Arkrose, Sun Bonnet, Zenith, Yeechunchilichal, Norm-24, Opaikjoke, Yangchubatchal and Nonglimana-1, Nams-97,-149, -159, -216. -265, Iri-243, -265, Kanchuk -5, -7, -8, -10, -41, -43, -47, -50, Suwon-56, -77, Norin-22, Cod-4. Lacrose and Chukna were susceptible. 5. There was slight differance in the disease occurrence in regard to maturing period. However late varieties seem to be more resistant than early or medium varieties. The medium varieties seem to be susceptible. Most of the introduced varieties from foreign countries and the upland cultivated varieties were resistant. 6 Among the leading varieties, Shin-2 in Kangwon-Do was resistant, Kosi in Choongchung-Do, was susceptible, aad the others were moderate.

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Relationship between atopic dermatitis and the Korean Healthy Eating Index score of adults: based on the 7th (2016-2018) Korea National Health and Nutrition Examination Survey (성인의 아토피 피부염과 식생활평가지수와의 관계: 국민건강영양조사 제7기 (2016-2018년) 자료 이용)

  • Kim, Hye Won;Kim, Ji-Myung
    • Journal of Nutrition and Health
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    • v.55 no.5
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    • pp.558-571
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    • 2022
  • Purpose: The purpose of this study was to analyze the dietary intake of Korean adults with atopic dermatitis (AD) to determine whether the risk of developing AD was related to their diet. Methods: Among the participants in the 7th National Health and Nutrition Survey (2016 to 2018), 10,571 adults aged 19-64 were divided into AD (AD group, n = 366) and control groups (non-AD group, n = 10,205) to compare and analyze their nutrient intake status and Korean Healthy Eating Index (KHEI) score. Depending on the prevalence of AD, the nutrient intake, nutrient intake per 1,000 kcal, acceptable macronutrient distribution range, and KHEI score were tested for significance by correcting for age, sex, body mass index, education, marriage, occupation, residence area, physical activity, and energy intake variables that were derived for confounding factors. Results: The acceptable macronutrient distribution range for protein was lower in the AD group than in the non-AD group. Comparing the nutrient intake per 1,000 kcal, the intakes of protein, phosphorus, iron, and potassium of the AD group were significantly lower than those of the non-AD group. In the KHEI, the scores of total vegetables, vegetables excluding kimchi and pickles, meat, fish, eggs, and legumes of the AD group were significantly lower than those of the non-AD group. In addition, as these food intake scores increased, the risk of AD significantly decreased. Conclusion: In conclusion, adult AD patients had low intakes of vegetables, meat, fish, eggs, and legumes, and it was confirmed that high intakes of these foods may be associated with low AD risk. Therefore, we suggest that an adequate intake of vegetables and foods containing protein would be necessary for the management and treatment of AD in adults.

요통의 주된 원인이 되는 근육질(Muscle Quality)향상을 위한 재활프로그램 모델개발

  • 라웅칠
    • Journal of Korean Orthopaedic Sports Medicine
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    • v.1 no.2
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    • pp.115-117
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    • 2002
  • 목적: 척추에통증을유발하는주된원인인근육질(Muscle Quality)의저하를향상시키는데있어서비교적안정적인방법(약물혹은수술이아닌요법)을시행하여치료중조직손상과부작용을최소화하면서신속한치료가이루어지는치료방법을찾는데주안점을두었다. 대상및방법: 임상실험기간은6주이었으며대상은평균연령34세(17 $\~$ 42세), 남녀30명,발병된지1년이상지난만성요통환자로서, 치료방법은근육마사지요법과운동요법을선택하였다.1군은근육마사지요법만을시행하였고, 2군은운동요법만을시행하였으며, 3군은근육마사지요법과운동요법을동시에병행하였다. 결과: 유연성측정결과와InBody 3.0에서의체성분결과를토대로분석한결과근육마사지요법만을시행한1군은즉각적인호전현상은보였으나시간경과후6일안으로다시이전의증상이원상복귀되어증상이개선되었다고보기는어려워보였다.한편운동요법만을시행한2군은연령에따른개인차는있었고6주안에만족할만한개선결과를보이지는않았지만증상개선이서서히이루어지고있었다. 그러나근육마사지요법과운동요법을병행한3군은1군과2군의실험결과와2단계이상의통증지수향상이관찰되었다. 결론: 요통의주된원인이되는근육질(Muscle Quality)의향상은근육질에긍정적인영향을주는모든요법중어느한가지를사용하는것보다는보다다각적인치료방법을개발하여적용시킬필요성이있다고사료된다.

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Economic impact of COVID-19 on water industry (코로나19 대유행이 물산업에 미치는 경제적 영향)

  • Choi, Han Ju;Ryu, Mun Hyun;Choi, Hyo Yeon
    • Proceedings of the Korea Water Resources Association Conference
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    • 2020.06a
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    • pp.77-77
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    • 2020
  • 2019년 12월 발병한 코로나19(COVID-19)는 높은 전파력을 바탕으로 세계적으로 대유행하면서 사람들의 생명, 건강을 비롯하여 생산·소비활동까지 위협하고 있다. 코로나19는 치료제 개발 전까지 실물경제에 직접적으로 타격을 주면서 국내외 경제 전반에 악영향을 지속적으로 미칠 것으로 예상된다. 특히 외부활동 및 소비심리 위축으로 숙박, 음식, 관광, 문화, 여행 등의 대면서비스 업종의 심각한 매출 감소 및 고용악화가 발생하고 있으며, 이 외 대부분의 산업에서도 생산과 소비활동이 위축되고 있다. 이러한 소비·생산활동의 위축은 각 산업에 필요한 중간재 수요, 특히 필수재인 물이용에도 영향을 미치게 된다. 이에 본 연구에서는 코로나19 확산으로 소비가 감소할 경우 전산업과 물산업에 미치는 경제적 손실을 1년간의 모든 실물거래 관계를 행렬로 기록한 통계표인 산업연관표(input-output table)을 활용하여 분석해보았다. 이를 위해 전월대비 3월 소비자심리지수 하락 폭을 참고하여 소비 감소에 따른 시나리오 분석을 산업연관분석을 통해 실시하다. 분석결과, 5개월 동안 소비가 20% 감소하는 경우 전산업과 물산업에서 각각 48.3조원과 886억원의 생산감소가 발생하며, 부가가치는 각각 21.7조원과 451억원이 감소하는 것으로 분석되었다.

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