• The Korean Journal of Zoology
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• v.39 no.3
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• pp.239-247
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• 1996

An embryonic stem (ES) cell-based in vitro model system was examined to determine whether a simple differentiation of embryoid bodies (EB) in the suspension medium is useful to dissect early erythropoiesis. Characteristics of the differentiating EBs were monitored for their differentiation potential to generate hematopoietic cell types by general morphology, benzidine staining and two-step colony assays, and expressivity of several erythroid marker genes by the RT-PCR analysis for total cellular RNA prepared from the differentiating EBs. Every ematopoietic lineage cells were generated from the differentiating EBs with reproducible frequencies, similar to the other sophisticated differentiation protocols. Furthermore, the globin gene switching in differentiating ES cells paralleled the sequence of events found in the mouse embryo, and such that their expression was activated by at least 12 hrs later than those of erythroid-specific transcription factors, GATA-1 and Tal-1 The erythropoietic differentiation program initiated reproducibly and efficiently in this simple differentiation system in a suspension culture, such that this system may be useful for dissection of the molecular events of early erythropoiesis.

• Journal of the Earthquake Engineering Society of Korea
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• v.12 no.1
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• pp.79-87
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• 2008

Seismic performance evaluation of structure requires an estimation of the structural performance in terms of displacement demand imposed by earthquakes on the structure. Incremental Dynamic Analysis(IDA) is a analysis method that has recently emerged to estimate structural performance under earthquakes. This method can obtained the entire range of structural performance from the linear elastic stage to yielding and finally collapse by subjecting the structure to increasing levels of ground acceleration. Most structures are expected to deform beyond the limit of linearly elastic behavior when subjected to strong ground motion. The nonlinear response history analysis(NRHA) among various nonlinear analysis methods is the most accurate to compute seismic performance of structures, but it is time-consuming and necessitate more efforts. The nonlinear approximate methods, which is more practical and reliable tools for predicting seismic behavior of structures, are extensively studied. The uncoupled modal response history analysis(UMRHA) is a method which can find the nonlinear reponse of the structures for ESDF from the pushover curve using NRHA or response spectrum. The direct spectrum analysis(DSA) is approximate nonlinear method to evaluate nonlinear response of structures, without iterative computations, given by the structural linear vibration period and yield strength from the pushover analysis. In this study, the practicality and the reliability of seismic performance of approximate nonlinear methods for incremental dynamic analysis of mixed building structures are to be compared.

• KIPS Transactions on Software and Data Engineering
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• v.5 no.12
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• pp.623-634
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• 2016

Most of existing frequent pattern mining methods address time efficiency and greatly rely on the primary memory. However, in the era of big data, the size of real-world databases to mined is exponentially increasing, and hence the primary memory is not sufficient enough to mine for frequent patterns from large real-world data sets. To solve this problem, there are some researches for frequent pattern mining method based on disk, but the processing time compared to the memory based methods took very time consuming. There are some researches to improve scalability of frequent pattern mining, but their processes are very time consuming compare to the memory based methods. In this paper, we present PPFP as a novel disk-based approach for mining frequent itemset from big data; and hence we reduced the main memory size bottleneck. PPFP algorithm is based on FP-growth method which is one of the most popular and efficient frequent pattern mining approaches. The mining with PPFP consists of two setps. (1) Constructing an IFP-tree: After construct FP-tree, we assign index number for each node in FP-tree with novel index numbering method, and then insert the indexed FP-tree (IFP-tree) into disk as IFP-table. (2) Mining frequent patterns with PPFP: Mine frequent patterns by expending patterns using stack based PUSH-POP method (PPFP method). Through this new approach, by using a very small amount of memory for recursive and time consuming operation in mining process, we improved the scalability and time efficiency of the frequent pattern mining. And the reported test results demonstrate them.

• Applied Chemistry for Engineering
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• v.4 no.4
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• pp.753-759
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• 1993

The research and motor octane numbers (RON & MON, respectively) of a gasoline are dynamic measures of its quality of performance as a fuel. ASTM standard engine test methods (RON:ASTM D-2699, MON:ASTM D-2700) have been used for determining the octane numbers (RON,MON)of gasolines. But these methods have been widely criticized because their repeatability and reproducibility of the test method are very poor. In addition to these objections, the cost and operation time involved in measuring by the standard method led to searches for "non -engine" methods (Gas Chromatographic method, Nuclear Magnetic Resonance Spectroscopic method). In this study, we determined the carbon type structural compositions of the gasolines by $^{13}C-NMR$ spectroscopy and predicted the octane number (RON & MON) with good accuracy. we presented an assessment of the effects of molecular structural composition on octane numbers.

• Proceedings of the Korea Water Resources Association Conference
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• 2019.05a
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• pp.281-281
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• 2019

수리모형실험은 수로 내에서 장시간 파랑을 발생시킬 경우, 수로 내에 반사 파랑의 성분이 누적될 수 있어 상당한 계측 오차를 발생시킬 우려가 있어 수리모형실험 결과의 검증이 필요하다. 일반적으로 수리모형실험 결과의 검증을 위해서는 동일 실험을 무수히 반복하여 불확실성을 제거하거나 다양한 수리실험실에서 수리모형실험을 수행하고 결과를 분석하여 불확실성을 제거할 수 있다. 그러나 이는 엄청난 시간과 노력은 물론 막대한 실험비용이 소요되기 때문에 경제적으로 효용성이 매우 낮아 현실적으로 수행이 어렵다. 이에 비해 수치모형실험은 상대적으로 저렴한 비용으로 수행할 수 있으며, 다수의 실험을 수행하지 않아도 불확실성을 제거할 수 있어 수리모형실험의 검증에 효율적이다. 일반적으로 난류 거동을 동반하는 복잡한 구조물 주변의 흐름 해석에는 3차원 CFD 모형이 필요하다. 특히, 병렬연산이 가능한 CFD 모형을 활용하면 수리모형실험에서도 재현이 쉽지 않은 다양한 조건에 따른 복잡한 흐름을 해석할 수 있어 효용성이 점점 증가하고 있다. 그러나 복잡한 구조물이 존재하게 되면 구조물에 재현에 막대한 격자구조가 필요하여 현실적으로 적용이 쉽지 않다. 이에 대한 대안으로 복잡한 구조물을 비교적 큰 격자에서 재현할 수 있는 가상경계법을 활용하는 연구가 활발히 진행되고 있다. 가상경계법은 Navier-Stokes 방정식에서 유체 내에 존재하는 고체를 모멘텀 이론으로 대체하여 고려하는 기법으로 수치모델링 수행 시 매질을 유체만으로 구성할 수 있어 안정적으로 적용할 수 있는 것으로 알려져 있다. 본 과업에서는 다양한 분야에서 널리 활용되고 있는 3차원 CFD 모형인 OpenFOAM®기반으로 파랑해석에 필요한 경계조건을 계산할 수 있는 olaFlow를 활용하여 복잡한 구조물을 지나는 파랑해석을 수행하기 위해 가상경계법을 olaFlow에 도입한 수치 알고리즘을 개발하였다. 개발한 수치알고리즘을 활용하여 복잡한 구조를 수치모델에서 재현하였으며, 수치모델에 적용된 수치 알고리즘의 안정성에 대해 고찰하였다.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.25 no.11
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• pp.1655-1662
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• 2021

The purpose of this study is to draw implications through a case study on the curriculum operation of a professor who operated a programming subject as a PBL(project-based learning) method in an untact situation due to COVID-19. A survey was conducted for first-year freshmen students to determine their learning condition before project implementation. Based on the results of the questionnaire, individual interviews were conducted to identify the needs for education, and then, basic grammar for project completion and lectures that segmenting each stage of the project were composed. Repeated learning was induced through weekly quizzes, and feedback was given by giving time in advance until the project deadline. 23 students (40 students in total) completed the project. The remaining 17 students took the exam but did not complete the project. The purpose of this study is significant in that it investigated whether a project can be carried out through instructional design, execution, and interaction while operating a programming subject through PBL in the COVID-19 environment.

• Journal of the Earthquake Engineering Society of Korea
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• v.7 no.2
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• pp.75-84
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• 2003

Most structures are expected to deform beyond the limit of linearly elastic behavior when subjected to strong ground motion. Seismic evaluation of structure requires an estimation of the structural performance in terms of displacement demand imposed by earthquakes on the structure. The nonlinear response history analysis(NRHA) among various nonlinear analysis methods is the most accurate to compute seismic performance of structures, but it is time-consuming and necessitate more efforts. The nonlinear approximate methods, which is more practical and reliable tools for predicting seismic behavior of structures, are extensively studied. Among them, the capacity spectrum method(CSM) is conceptually simple, but the iterative procedure is time-consuming and may sometimes lead to no solution or multiple solutions. This paper considers a nonlinear direct spectrum method(NDSM) to evaluate seismic performance of mixed building structures without iterative computations, given dynamic property T from stiffness skeleton curve and nonlinear pseudo acceleration $A_{y}$/g and/or ductility ratio $\mu$ from response spectrum. The nonlinear response history analysis has been performed and analyzed with various earthquakes for estimation of reliability and practicality of NDSM with mixed building structures.

• Proceedings of the Computational Structural Engineering Institute Conference
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• 2009.04a
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• pp.279-282
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• 2009

본 논문에서는 행렬응축기법 및 부구조기법을 이용하여 가변형 입체 복합 공간 구조물을 효율적으로 해석할 수 있는 해석기법을 제안하였다. 최근 구조공학의 발전과 더불어 다양한 사회적 경제적 요구에 의해 가변형 입체 복합 공간 구조물에 대한 연구가 진행되고 있다. 가변형 입체 복합 공간 구조물은 많은 구조부재가 필요 하며, 부재 수가 많아짐에 따라 각 절점이 가지는 자유도수가 크게 증가하여 초기 해석 과정에서 많은 시간이 요구된다. 또한 구조물이 변경되는 경우에는 변경되는 부분의 강성의 변화에 따라 전체 구조물의 강성이 변경되므로 이에 따른 전체 구조물의 재해석 과정이 필요하다. 이러한 점에서 구조물의 자유도수를 줄여주는 행렬응축기법과 반복적인 해석과정을 줄여주는 부구조기법은 가변형 입체 복합 공간구조물을 효율적으로 해석 할 수 있는 방법이 될 수 있다. 본 논문에서는 행렬응축기법과 부구조기법을 이용하여 가변형 입체 복합 공간 구조물을 효율적으로 해석할 수 있는 해석기법을 제안하고, 이를 토대로 구체적인 알고리즘을 작성하였다. 또한 알고리즘을 구체화시켜 가변형 입체 복합 공간 구조시스템에 적합한 구조해석 프로그램을 개발하여 예제 구조물에 대하여 구조해석을 수행하였으며, 구조해석 결과를 상용프로 그램의 구조해석 결과와 비교하여 해석기법에 대한 정확성 및 효율성을 검토하였다.

• Journal of the Korea institute for structural maintenance and inspection
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• v.21 no.1
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• pp.83-90
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• 2017

The corrosion behavior of a rebar in concrete according to the amount of NaCl and $LiNO_2$ was observed by using Electrochemical Impedance Spectroscopy. The corrosion was accelerated in a short time by using dry/wet cycles method, which is one of the corrosion acceleration methods, and though the value of measured impedance, equivalent circuit can be introduced. It was confirmed that the passive film of a embedded rebar in concrete with NaCl was broken quickly, and when $0.6M\;LiNO_2$ was added, the velocity of ongoing corrosion was declined considerably compared to the amount of NaCl. However, when $1.2M\;LiNO_2$ was added, it was confirmed that the passive film was not broken and its performance remained, compared to the amount of NaCl.

• Korean Chemical Engineering Research
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• v.47 no.1
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• pp.133-140
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• 2009

This paper presents the experimental study to analyze the pressure and production behavior using depressurization and thermal methods in order to evaluate the hydrate productivity in the 2-D multi-well, plate-type apparatus which has 80 md permeability and 30% hydrate saturation. Injecting methane gas through multi-well allowed to set up the highly saturated hydrate system and combining two different sorts of sands made possible to build up the low permeability system. In this system, both depressurization and electric stimulation methods were applied. When operating pressure was low, according to the depressurization experiments results, the gas recovery was high, however strong pulses which appeared at initial stage of production would damage the operation system. Moreover, cases that hydrate reformed have occurred by endothermic reaction. We have conducted experiments four and six times for the depressurization magnitudes of 140 psi and 320 psi, respectively, to analyze production behavior for the method more in detail. For the cases that the depressurization magnitude was set as 140 psi, the unstable period appears in the results, but stabilized soon. In the experiment results for 320 psi the discontinuous and intermittent behavior has been observed. Thermal stimulation experiments was conducted with depressurizing 80 psi which is the case that shows stable behavior and low recovery. In the results, the gas recovery was high and the energy efficiency was low for long stimulating time. The energy efficiency and gas recovery increased for the soaking time of 1 minute after 2 minute-preheating. In the cases of which the soaking time exceeds 1 minute, energy loss by long soaking time caused low gas recovery and poor energy efficiency.