• Title/Summary/Keyword: 바이오 기능성

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Preparation and Anti-fouling Properties of PVDF Mixed Matrix Asymmetric Membranes Impregnated with 𝛽-cyclodextrin (𝛽-사이클로덱스트린을 함침시킨 PVDF 혼합기질 비대칭막의 제조와 내오염성 평가)

  • Shin, Sung Ju;Lee, Jong Sung;Lee, Jeong Gil;Youm, Kyung Ho
    • Membrane Journal
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    • v.31 no.6
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    • pp.434-442
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    • 2021
  • Poly(vinylidene fluoride) (PVDF) membrane has a good membrane durability because of its high mechanical resistance, thermal and chemical stability. However, the strong hydrophobic property of PVDF membrane can induce a low water permeability and easy fouling by proteins and organic matters. In order to improve the anti-fouling properties of PVDF membrane, the PVDF mixed matrix asymmetric membranes impregnated with biofunctional material 𝛽-cyclodextrin (𝛽-CD) in the membrane structure were prepared by phase inversion method. The membrane filtration experiments of pure water and BSA solution were performed using the PVDF/𝛽-CD mixed matrix asymmetric membranes prepared according to the 𝛽-CD contents. The experiments showed that the introduction of 𝛽-CD into the PVDF polymer matrix contributed to increase in the hydrophilic property of the PVDF membranes, and this led to the reduction of contact angles and improvement of anti-fouling properties. The PVDF/𝛽-CD membrane which was prepared using the dope solution with a 2 wt% 𝛽-CD content represented 64 L/m2·h of pure water flux, 95% of BSA rejection and maximum 80% of flux enhancements compared to flux results of the pristine PVDF membrane.

Stability of the enzyme-modified starch-based hydrogel model premix with curcumin during in vitro digestion (효소변형 전분기반 하이드로젤 모델 프리믹스 내 탑재된 커큐민의 소화과정 중 안정성)

  • Kang, Jihyun;Rho, Shin-Joung;Lee, Jiyoung;Kim, Yong-Ro
    • Korean Journal of Food Science and Technology
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    • v.53 no.4
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    • pp.365-374
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    • 2021
  • In this study, the effect of enzyme-modified starch used in the preparation of filled hydrogel powder loaded with curcumin (FHP) on redispersibility, thermal and UV stability, and curcumin retention during in vitro digestion was investigated. FHP maintained stability without layer separation when redispersed and showed more stability against UVB than the emulsion powder (EMP). There was no significant difference in the chemical stability of curcumin between rice starch-based filled hydrogel powder (RS-FHP) and enzyme-modified starch-based filled hydrogel powder (GS-FHP). However, the gel matrix of GS-FHP maintained greater stability of lipid droplets in the stomach compared to RS-FHP, thereby improving the retention rate of curcumin after in vitro digestion. GS-FHP could be used as a novel material for developing premixes that require stable formulation and maintenance of functional substances, as it can increase the dispersion stability and retention rate of functional substances after digestion.

Effect of resistance training on joint flexibility and muscle strength of upper extremities of elderly with impaired cognition (탄력저항성운동 프로그램이 인지기능저하 노인의 상지유연성 및 근력에 미치는 효과)

  • Kim, Shinmi;Lee, Yunjung;Kim, Hwanjoong
    • 한국노년학
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    • v.29 no.3
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    • pp.987-1000
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    • 2009
  • The purpose of the study was to examine the effect of resistance training on joint flexibility and muscle strength of upper extremities of institutionalized elderly with impaired cognition. The study design was pretest-posttest control group study and inclusion criteria were elderly aged 65-year older, MMSE score 23 or less, ones who had no serious physical and/or mental problem except impaired cognition, and were capable to carry out resistance training. After consents were obtained participants were randomly assigned. Pre-post evaluation was performed by staff nurses trained beforehand. Among those 4-week study period, experiment was carried out during 5 consecutive days a week for 3 weeks. ROM and extension range of shoulder joints and muscle strength of shoulders and hands for both sides were measured. Flexion, extension, abduction range of right shoulder joint was significantly improved. Flexion and extension muscle strength of left side shoulder and abduction muscle strength of both sides of shoulder were significantly improved. With the study result, it could be concluded that resistance training has therapeutic effects on joint flexibility and muscle strength. More studies adopted longer experimental period to evaluate timing of effect and extinction to refine the protocol are called for.

The Development of Computerized Sport-related Cognitive Test Battery to Measure Sport Intelligence, the Ability to Read the Game (게임을 읽는 머리, 스포츠지능을 측정하기 위한 컴퓨터 기반 스포츠 인지검사 프로그램 개발)

  • Park, Jin-Han;Woo, Min-Jung
    • Journal of the Korea Convergence Society
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    • v.12 no.7
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    • pp.19-29
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    • 2021
  • High-performing athletes possess the ability to read the game, known as the "sports brain". However, a cognitive battery to measure such sports brain has not been developed yet. The purpose of the study, thus, is to develop a computerized cognitive test battery to measure athletes' cognitive function. Based on a systematic review, information processing speed, execution function, and spatial ability were selected as sports-related cognitive functions. Simple and choice response times test, trail-making test, Flanker test, and mental rotation task were developed. After providing manual and practice trials, main tests were executed and all primary variables were statistically processed and automatically saved. The test battery is expected to aid in the discovery and recruitment of athletes in the future after verifying the validity and reliability of this battery.

A Comparative Analysis between High and Low Groups on Concerns About Privacy Infringement in Consumer Innovation Patterns According to Internet Media Activities (인터넷 미디어 활동에 따른 소비자 혁신성 유형이 프라이버시 침해 우려성에 대한 고(High)집단과 저(Low)집단 간의 비교 분석)

  • Lee, Ji-Hun;Kang, Jun-Mo;Lee, Jeong-Suk
    • Journal of Korea Entertainment Industry Association
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    • v.14 no.7
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    • pp.193-202
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    • 2020
  • This study was intended to present the magnitude of privacy infringement concerns and their relationship to consumer innovation (functional innovation, hedonistic innovation, social innovation, cognitive innovation), to identify differences among groups and to suggest implications for marketing strategies for the spread of new products. The implications of this study are as follows. First, functional innovation has shown that differences exist between groups. Analysts say that sensitive groups are buying products that can simplify their work immediately after release despite concerns over privacy violations. Second, hedonistic innovation has shown that differences exist between groups. These findings suggest that sensitive groups prefer novel products, products that give excitement and excitement about products, and products that give new enjoyment and fun that they have never known before. Third, social innovation has been shown that there is no difference between groups. These analyses show that the self-esteem of using products that others have never experienced before, and the curiosity that anyone envies, are purchased or used first. Finally, cognitive innovation showed that differences existed between groups. These analyses show that new products are purchased when they meet the functions, design, and innovation that consumers want.

Quality Characteristics of Health Concerned Funtional Cookies using Crude Ingredients (거친재료를 첨가한 건강기능성 쿠키의 품질 특성 연구)

  • Kang, Nam-E;Kim, Hye-Young L.
    • Journal of the Korean Society of Food Culture
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    • v.20 no.3
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    • pp.331-336
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    • 2005
  • Pysicochemical and sensory characteristics of health concerned funtional cookies using various levels of crude ingredients of resistant starch were investigated in this study. The 10% substituted group had significantly higher pH values compared to those of control. Spread factor of control group had significantly the largest value and the 30% substituted group had the lowest values(p<0.05). Results of sensory characteristics showed significantly higher hardness, crispness and yellowness with 20% substituted sample group at p<0.05. Acceptance test of cookies with 10% substituted sample groups showed higher savory taste, texture, and overall acceptability and they did not show significant differences with the 20% substituted groups.

Development of satellite precipitation process module based on QGIS (QGIS 기반 위성강수 처리 모듈 개발)

  • Kim, Joo Hun;Kim, Kyeong Tak;Jo, Minhye
    • Proceedings of the Korea Water Resources Association Conference
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    • 2019.05a
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    • pp.60-60
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    • 2019
  • OECD 발표에 의하면 물산업 관련 인프라 투자 전망은 전세계 GDP 대비 2010~2020년 약 1.01%에서 2020~2030년 약 1.03%로 확대될 전망으로 다른 통신, 전력, 철도 인프라 투자수요보다 많을 것으로 전망하고 있다(파이넨셜 뉴스, 2013.3.21.). 우리나라는 2005년 베트남 홍강종합개발사업을 시작으로 2015년 기준으로 세계 35개국에 진출하고 있다. 그러나 대부분의 물 산업 진출 대상 국가는 미계측 유역이 많고 지상에서 계측된 수문 자료가 부족한 실정이다. Namgung and Lee(2014)에 의하면 네팔의 수력발전소 건설에 관측된 강우량 자료가 없어 발전소 하류 10km 지점의 유하량 자료를 이용하여 자료의 정확도 검증을 대신하여 적용한 바 있다. 이와 같이 계측자료가 없거나 부족한 지역에 대하여 기상 위성을 이용하여 추정된 강수량 자료가 해당 지역의 강수 특성을 파악하는데 중요한 자료로 이용될 수 있다. 글로벌 위성 기반의 강수량 관측에 대한 역사는 1979년에 IR방법에 의해 위성으로부터 강우자료를 유도하는 개념이 도입된 이후 1987년 다중 채널의 마이크로파(MW) 복사계를 이용한 방법, 이후 두 IR과 MW를 혼합한 방법에서, 1997년 TRMM위성의 PR(Precpipitation Radar)의 레이더를 이용하는 방법, 그리고 2014년 GPM 핵심 위성(GPM Core Observatory)에 탑재된 Dual PR에 의한 방법으로 위성강수의 정확도를 매우 높여가고 있다. 본 연구는 대표적인 위성강수인 IMERG(Integrated MultisatellitE Retrievals for GPM)의 활용성을 높이기 위해 QGIS 기반의 위성강수 전처리 모듈을 개발하는 것을 목적으로 하고 있다. 위성강수를 활용하기 위해서는 위성강수의 정확도 평가가 선행되어야 한다. 본 연구를 통해 2017년 7월 중부지방 및 충청도 지방에 내린 강수자료를 비교한 결과 상관계수가 약 0.7정도로 상관성이 높은 것으로 분석되었고, 2018년 8월 9호 태풍 솔릭(Solik)에 대한 1시간의 시간해상도 분석 결과 상관계수 0.624로 위성강수의 활용성이 있음을 입증하였다. IMERG 위성강수의 활용성을 높이기 위하여 HDF5 포맷의 원시자료를 활용이 용이한 Tiff 로 변환하는 기능에서부터 특정범위 및 특정지점 추출 기능, Resampling 기능 등을 포함하는 전처리 모듈을 개발하였다.

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Diagnosis and Prognosis of Sepsis (패혈증의 진단 및 예후예측)

  • Park, Chang-Eun
    • Korean Journal of Clinical Laboratory Science
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    • v.53 no.4
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    • pp.309-316
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    • 2021
  • Sepsis is a physiological response to a source of infection that triggers mechanisms that compromise organ function, leading to death if not treated early. Biomarkers with high sensitivity, specificity, speed, and accuracy that could differentiate sepsis from non-infectious systemic inflammatory response syndrome (SIRS) could bring about a revolution in sepsis treatment. Given the limitations and time required for microbial verification of pathogens, the accurate diagnosis of infection before employing antibiotic therapy is important and clinically necessary. Procalcitonin (PCT), lactate, C-reactive protein (CRP), cytokines, and proadrenomedullin (ProADM) are the common biomarkers used for diagnosis. The procalcitonin (PCT)-guided antibiotic treatment in patients with acute respiratory infections effectively reduces antibiotic exposure and side effects while improving survival rates. The evidence regarding sepsis screening in hospitalized patients is limited. Clinicians, researchers, and healthcare decision-makers should consider these findings and limitations when implementing screening tools, future research, or policy on sepsis recognition in hospitalized patients. The use of biomarkers in pediatric sepsis is promising, although such use should always be correlated with clinical evaluation. Biomarkers may also improve the prediction of mortality, especially in the early phase of sepsis, when the levels of certain pro-inflammatory cytokines and proteins are elevated.

Growth of Candida albicans Biofilm is Inhibited by Salvia miltiorrhiza (단삼에 의한 Candida albicans 바이오필름 발달의 억제)

  • Lee, Heung-Shick;Kim, Younhee
    • Microbiology and Biotechnology Letters
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    • v.47 no.3
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    • pp.465-472
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    • 2019
  • Candida albicans is an opportunistic human pathogen that causes infections. Candidiasis is often related to antifungal resistance because the pathogen has the ability to form biofilms. In a previous study, we found that the Salvia miltiorriza ethanol extract demonstrated anticandidal activity by altering membrane permeability and inhibiting the cell wall synthesis in C. albicans. Our results here demonstrate that $78{\mu}g/ml$ of the S. miltiorriza extract significantly diminished the early stage biofilms formed by 10 clinical C. albicans isolates by 51.3%; this was analyzed by 2,3-Bis-(2-methoxy-4-nitro-5-sulfophenyl)-2H-tetrazolium-5-carboxanilide salt (XTT) reduction assay. The effect of the S. miltiorrhiza extract on the adhesion of C. albicans cells to polystyrene plates and germ tube formation was examined via microscopic investigation. Although the density of the adhered cells was remarkably reduced up on incubation with $39{\mu}g/ml$ S. miltiorrhiza extract, germ tube formation by C. albicans was rarely affected. Quantitative real-time PCR analysis showed that the S. miltiorrhiza extract downregulated the expression of C. albicans hypha-specific genes, EAP1 by 34.7% (p < 0.001), ALS1 by 45.0% (p < 0.001), ALS3 by 48.1% (p < 0.001), and ECE1 by 21.3% (p = 0.006), respectively. Our data suggest that the S. miltiorrhiza ethanol extract significantly inhibited the early stage of biofilm formation by C. albicans by interfering with cell adhesion, by downregulating EAP1, ALS1 and ALS3, and presumably by modifying the cell wall and membrane structure.

A Study on Fish Movement Efficiency in Biopolymer and Aggregate Mixed Fishway (피마자유기반 바이오폴리머와 골재를 혼합한 어도의 어류이동효율 실험연구)

  • Dong-Jin Lee;Min Ho, Jang;Joongu Kang;Hong-Kyu Ahn
    • Ecology and Resilient Infrastructure
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    • v.11 no.1
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    • pp.11-22
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    • 2024
  • A fishway is an artificial waterway or device used to resolve difficulties in the movement of fish in a river. Most existing fishways are made of concrete and emit toxic substances, which has a negative impact on the river environment. Accordingly, there is a need to develop fishway construction technology that is eco-friendly and can increase movement efficiency. The technology presented in this study is an integrated porous structure that combines the aggregate with a biopolymer material extracted from castor oil, a non-toxic material. It is a fishway construction technology using eco-friendly materials that can allow vegetation to grow on the surface. In this study, an eco-friendly fishway mixed with biopolymer and aggregate was built on a real scale and the fish movement efficiency was tested and analyzed. As a result of the experiment, a total of 201 fish of 14 species were released with tags inserted, and the detection rate of released fish was confirmed to be 82.6% on average. A total of 40 fish of 6 species were transported upstream through the fishway, and the average passage rate was confirmed to be 21.7%. As a result of checking the circadian migration pattern, it was found that all fish mainly migrate during the day. It was confirmed that there was no significant functional difference between a fishway using biopolymer and a concrete fishway. It is believed that a fishway using biopolymer can be used as a replacement for a concrete fishway.