• Journal of the korean academy of Pediatric Dentistry
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• v.43 no.2
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• pp.200-206
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• 2016

Root fracture is defined as a fracture involving the dentin, cementum, and pulp. Most fractures occur in the maxillary anterior teeth between the ages of 11 and 20 years old. The treatment for root fracture in permanent teeth involves the reduction and fixation of the displaced coronal segment. When signs of pulp necrosis or inflammatory root resorption are present, root canal therapy should be performed. Since most apical fragments maintain pulp vitality, root canal therapy is typically limited to coronal fragments. However, it's too difficult to achieve a proper apical stop on coronal fragment. Intentional replantation involves performing root apex treatment outside the mouth after intentional extraction of the tooth in a controlled environment and then replanting it. The objective is 'perfect' root canal therapy. Intentional replantation may be used in cases of failed typical root canal therapy, problematic endodontic retreatment due to the existing restoration or a calcified root canal, and when apical surgery is contraindicated because of a lack of reasonable approaches. In this case, intentional replantation was carried out to treat a horizontal root fracture in a maxillary central incisor with a calcified root canal due to previous trauma. We achieved a clinically and functionally satisfactory result.

• Journal of the korean academy of Pediatric Dentistry
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• v.36 no.3
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• pp.456-463
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• 2009

Cleidocranial dysplasia(CCD) is a congenital disorder of skeletal and dental abnormality, which is a mesodermal dysfunction influencing many tisssues and organs. Skeletal abnormalities in CCD are delayed closure of cranial suture and fontanelle, presence of wormian bone and clavicle aplasia. CCD also has an effect on long bones, phalanges, spine, pelvis, muscles, and central nervous system. Dental manifestations include retention of deciduous teeth, multiple supernumerary teeth, delayed eruption or impaction of permanent teeth and formation of cysts around nonerupted teeth. However, due to lack of any substansive medical or physical disability, diagnosis is often late, thereby causing masticatory and psychological problems caused by delayed eruption of permanent teeth after exfoliation of deciduous teeth. For this reason, CCD requires early diagnosis, and the patient's appearance must be improved. Also, provision for a functional masticatiory mechanism by treatment of surgical removal of supernumerary teeth followed by orthodontic eruption of the natural permanent teeth at an adequate time is necessary.

• Asia-Pacific Journal of Business Venturing and Entrepreneurship
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• v.15 no.1
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• pp.31-44
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• 2020

Accelerators that invest in early startups, as well as nursery and overall management, have recently emerged as "key players" in the startup ecosystem. This can be proved by the case where the number of domestic accelerators registered in the Korean Ministry of SMEs and Startups has recently reached 208. Accelerators provide the necessary education for early-stage companies, including guidance for a certain period of time, and support startups in ways such as demo days to attract subsequent investment after the seed investment. There is not much research in academia about what factors impact on these accelerators when making investment decisions at the time of seed investment. In this study, we checked the meaning and function of the accelerator and tried to analyze what factors affect on accelerators when making a decision to invest in startups. The research method is based on a literature survey of previous studies on investment decision-making factors of venture capital and angel investors, and a lens model and judgment analysis method through empirical research targeting 43 accelerator investment decision-makers. Empirical analysis shows that accelerators have three of the key factors to consider when choosing the first startup to invest and educate; entrepreneurs' entrepreneurial traits, their product and service expertise and a potential return on success. This will provide an opportunity for early startups to gain strategic access to accelerators when they need money or need a structured educational program. Also, the results obtained through this research will be a kind of guideline for startups to attract accelerators' investment. The significance of this study is that discriminatory evidence was presented on the accelerator determinants of investment, and it would be highly suggestive to startups and related public institutions.

• Journal of The Korean Society of Inherited Metabolic disease
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• v.15 no.2
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• pp.87-92
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• 2015

Mucopolysaccharidosis (MPS) is an inherited disease entity associated with lysosomal enzyme deficiencies. MPS type 2, also known as Hunter syndrome, has a characteristic morphology primarily involving x-l inked recessive defects and iduronate-2-sulfatase gene mutation. The purpose of this case report is to provide important clues to help pediatricians identify Hunter syndrome patients earlier (i.e., before the disease progresses). A 30-month-old boy showed developmental delay and decreased speech ability. Physical examinations revealed a flat nose and extensive Mongolian spots. Brain magnetic resonance images (MRIs) showed bilateral multiple patchy T2 hyperintense lesions in the periventricular and deep white matter, several cyst-like lesions in the body of the corpus callosum, and diffuse brain atrophy, which were in keeping with the diagnosis. Based on these findings, the patient was suspected of having MPS. In the laboratory findings, although the genetic analysis of IDS (Iduronate-2-sulfatase) did not show any pathogenic variant, the enzymatic activity of IDS was not detected. We could confirm the diagnosis of MPS, because other sulfatases, such as ${\alpha}$-L-iduronidase, were detected in the normal range. Early enzymatic replacement therapy is essential and has a relatively good prognosis. Therefore, early diagnosis should be made before organ damage becomes irreversible, and brain MRIs can provide additional diagnostic clues to help distinguish the disorder.

• Journal of Chest Surgery
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• v.39 no.9 s.266
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• pp.714-717
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• 2006

Heart and kidney transplantation has made great progress in the modern era. Coupled with the growing successes in individual solid organ transplantation, there has also been an increase in the number of multiple organ transplants, such as heart-kidney transplantation. This trend has been in part due to a better understanding of immunobiology, advances in surgical technique and postoperative care, and an often-common pathologic association between dual-organ failure. This pathologic course is representative for end-stage heart failure leading to secondary renal dysfunction or failure, or for end-stage renal failure as a cause for (uremic) cardiomyopathy. However, refractory cardiac failure has long been considered a contraindication to kidney transplantation. Additionally, cardiac transplantation has been denied for patients with end-stage renal disease. Over recent years, combined heart-kidney transplantation has been offered to select patients who were once denied transplantation. We report the first experience of combined heart-kidney transplantation with one year follow-up results.

• Journal of the Korean Institute of Landscape Architecture
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• v.41 no.6
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• pp.185-198
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• 2013

The 2002 World Cup cheering in front of Seoul City Hall and Seoul Plaza design competition provided an opportunity for the discussion of a variety of discourses regarding our plaza culture. The Gwanghwamun Plaza constructed in 2009 also generated discussions for questions on the function of our plaza as a symbolic, humanistic and utilized place. The questions on whether we have created a plaza culture or what should be done for the design of our plaza are still being explored. The reason is that our plazas were constructed without social consensus regarding identity of our plaza while we are influenced by western plaza ideas. The principle of our plaza culture and shape is not yet discussed and determined. The emergence of discussion sparked by the Gwanghwamun Plaza and the Seoul Plaza can be seen as a positive phenomenon. If we can continue to build creative discourse, we will be able to establish our plaza cultures soon. In this context, the Ansan Gwangduk-ro theme plaza design can be a significant material to be discussed. The design competition for the plaza was held in 2009 and it is followed by the construction of the plaza in late 2010. Considering cultural and spatial issues on our plaza in mind, the project will be explained and the identity of the contemporary design will also be explored.

• The KIPS Transactions:PartD
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• v.9D no.6
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• pp.1055-1062
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• 2002

Recently, the lesson plan document that is imported in the educational area is not provided to the educational information systematically, and the teachers are not easy to compose the lessen plan documentation. So, it needs additional time and effort to develope the lesson plan documents. Because of increasing the distributing network. web-based lesson plan system is required to all of the education area. Therefore, we need to compose the lesson plan that is possible to obtain the various teacher's requirement by providing creation, retrival, and reusability of document using the standard XML on web. In this paper, we developed the system for creating the common DTD (Document Type Definition), providing the standard XML document through the common DTD over the lesson plan analysis. In this system, it provides the editor to compose the lesson plan and supports the searching function to improvement of reusability on the existing lesson plan. We design the searching functions such as the structure base, facet and keyword. The composed lesson plans are interoperated with Database. Consequently, we can share the information on web by composing the lesson plan using the XML and save the time and cost by directly writing the lesson plan on web. We can also provide the improved learning environment.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.21 no.9
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• pp.238-250
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• 2020

This study investigated the long-term measures to minimize flood damage in the event of flooding in urban areas. The relationship between urban spatial factors and the impact of flood damage was analyzed, focusing on non-structural measures. The urban spatial factors were categorized into three parts: open space, disaster prevention facilities, and urbanization sectors. Multiple regression analysis was used to investigate how urban spatial factors influence flood damage. As a result of the analysis, the crucial factors, such as the reduced green areas and parks included in the open space sectors, resulted in an increased flood damage potential. The posterior factors, such as the population density and GRDP included in the urbanization sector concurrently led to an increase in the flood damage potential. Therefore, to better adapt to climate change, it is necessary to establish urban spatial plans strategically, such as green areas and parks. Meanwhile, the population density and GRDP are also the main factors causing flood damage. Therefore, when used appropriately in terms of resilience, it will serve as adaptations and recovery.

• Journal of Plant Biotechnology
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• v.42 no.1
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• pp.19-24
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• 2015

Glycine betaine (GB) is one of the compatible solutes that accumulate in the chloroplasts of certain halotolerant plants under salt or cold stress. The codA gene for choline oxidase, the enzyme that converts choline into GB, has been cloned from a soil bacterium Arthrobacter globiformis. We generated transgenic sweetpotato plants [Ipomoea batatas (L.) Lam] expressing codA gene in chloroplasts under the control of the SWPA2 promoter (referred to as SC plants) and evaluated SC plants under oxidative and drought stresses. SC plants showed enhanced tolerance to methyl viologen (MV)-mediated oxidative stress and drought stress due to induced expression of codA. At $5{\mu}M$ of MV treatment, all SC plants showed enhanced tolerance to MV-mediated oxidative stress through maintaining low ion leakage and increased GB levels compared to wild type plants. When plants were subjected to drought conditions, SC plants showed enhanced tolerance to drought stress through maintaining high relative water contents and increased codA expression compared to wild type plants. These results suggest that the SC plants generated in this study will be useful for enhanced biomass production on global marginal lands.

• Korean Journal of Logic
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• v.16 no.3
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• pp.347-380
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• 2013

In this paper I will try to show how Wittgenstein criticized Frege's theory of meaning. Frege's theory of meaning can be compressed as sense-reference theory. Frege distinguishes between sense and reference on all the linguistic expressions. In particular, he regards that a sentence has sense and reference. This distinction was raised from, so to speak, the problem of identity sentences. Wittgenstein's "fundamental thought" of Tractatus Logico-Philosophicus is the key of his direct criticism of Frege's sense-reference theory. That is, it is an attack on Frege's thought that the reference of a sentence is a truth value and truth values are "objects themselves" (in Frege's meaning). According to Wittgenstein, such an object does not exist and according to his picture theory, the function of a name and that of a proposition are fundamentally different. By the way, Frege can reply justly to this criticism that it is insufficient. In short, Frege's 'sense' and 'reference' etc, are the technical terms. Hence Wittgenstein's decisive criticism of Frege's theory consists in accusing his theory of logical flaws. There is an another route to the sense and reference of a sentence which Frege introduces. In discourses of judgement stroke and content stroke in his Begriffsshrift and in those of horizontal stroke since his "Function and Concept", Frege deals with the sense and reference of a sentence. Wittgenstein criticize that the sense of a complex sentence such as ~p would by no means be determined by Frege's determination.