• Clinical and Experimental Pediatrics
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• v.46 no.10
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• pp.1029-1031
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• 2003

Hemophagocytic lymphohistiocytosis is a reactive disorder characterized by a generalized non-malignant histiocytic proliferation with prominent hemophagocytosis by stimulated histiocytes in the bone marrow and reticuloendothelial systems resulting in pancytopenia and liver dysfunction. Several diseases including infection, malignancy and autoimmune disease are known to be causative disorders. This case demonstrated histiocytic hemophagocytosis in the bone marrow, resulting in pancytopenia during treatment of systemic lupus erythematosus and did not show any underlying disease.

• Journal of Chest Surgery
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• v.40 no.12
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• pp.867-870
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• 2007

Antiphospholipid syndrome (APS) is defined as venous and/or arterial thromboses, recurrent fetal losses, thrombocytopenia in combination with repeatedly positive tests for the lupus anticoagulant (LAC), and anticardiolipin antibodies (aCL). The pulmonary manifestation is APS are relatively rare. We report a rare case of antiphopholipid syndrome with systemic lupus erythematosus in a patient who presented with pulmonary hypertension secondary to a chronic pulmonary thromboembolism. A bilateral thromboendarterectomy was performed satisfactorily and the incision was extended to the left intrapleural pulmonary artery.

• Journal of Yeungnam Medical Science
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• v.15 no.2
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• pp.371-380
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• 1998

Systemic lupus erythematosus(SLE) is an autoimmune disease which may affect many different organs and disclose various clinical manifestations. Recently central nervous system(CNS) involvement has been recognized as an increasingly significant contributor to morbidity and mortality of SLE. The clinical manifestations of CNS-lupus are highly variable and range from mild cognitive dysfunction, movement disorder, headache, psychosis to life-threatening stroke and coma. Among the neuropsychiatric disorders encountered in patients with SLE, cerebrovascular disease has been a relatively rare complication. The diagnosis and management of CNS-lupus is difficult because of the lack of useful diagnostic methods. If cerebrovascular involvement is suspected, aggressive treatment such as high dose steroid, immunosuppressive therapy, plasma exchange may be required to reduce high mortality rate. We experienced 2 cases cerebrovascular dis eases occurring in SLE patients which presented with various neuropsychiatric manifestations. They were diagnosed as CNS-lupus by neuropsychiatric symptoms, brain MRI, and BEG, and showed good response to high dose steroid pulse therapy.

• Clinical and Experimental Pediatrics
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• v.46 no.5
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• pp.440-446
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• 2003

Purpose : The genetic disturbance of galactosemia is expressed as a cellular deficiency of either galactose-1-phosphate uridyltransferase(GALT) or galactokinase(GALK) or UDP galactose 4-epimerase(GALE). To find-out the pattern of galactosemia in Korea, we retrospectively analyzed cases of galactosemia detected by neonatal screening program. Methods : We analyzed medical records of patients who visited Soonchunhyang University Hospital at age of 1 month after showing abnormalities in neonatal screening of galactosemia. For accurate diagnosis, galactose was measured by enzyme immunoassay(EIA) and fluorophotometer, also galactose-1-phosphate by fluorophotometer. Enzyme activities of GALK, GALT and GALE in RBC and galactose-1-phosphate were measured by radioisotope assay(RIA). Beutler test were done. Patients went on a lactose-free diet and follow-up tests for galactose, galactose-1-phosphate level and enzyme activity were performed. Results : 10 patients(male : 6, female : 4) were diagnosed as galactosemia. Two patients had GALK deficiency and two had GALT deficiency. Six were GALE deficient showing the largest number. In two patients with GALK deficiency, GALT and GALE activities were normal but GALK activities showed respectively reduced activity. For GALT deficiency, two patients had low GALT activity in RBC and showed genotype of Duarte 2/G(galactosemia) in DNA analysis. In one patient, GALT activity was normal. Three patients seemed to be heterozygote state of GALE deficiency according to GALE activity levels. Four patients showed GALK hyperactivity. Conclusion : GALE deficiency provided the highest number. After lactose-free diet, galactose and galactose-1-phosphate were normaly maintained. Neonatal screening on galactosemia is essential for preventing life-threatening symptoms and an accurate diagnosis is needed for finding out the type of galactosemia which is important for prognosis.

• Science of Emotion and Sensibility
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• v.14 no.1
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• pp.1-6
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• 2011

A perceptual reaction to human being's gaits has "regularity" that possibly obtains sympathy among people. This thesis is in the vein of the study that performs the research on the quantificational extraction of the regularity, reconstitute the result, and apply it to controlling behavior. The purpose of this thesis lies in assuring the validity of the future research by demonstrating the following hypothesis: when the physical numerical values of the gait "A" whose perceptual reaction is "a" and those of the gait "B" whose perceptual reaction is "b" are arbitrarily blended, the perceptual reaction to this blended gait also corresponds to the blend of "a" and "b", "a/b". I blended the samples of two types of gaits in the form of Bipeds using the EAM made by 3D Studio Max Script. Blending outcomes were obtained successfully for four times out of the six tries in total. It implies that without utilizing other methods such as Motion Capturing, the basic Bipeds data itself has an enough capability to generate various gaits of Bipeds. Although the present research targets only the Bipeds samples equipped with the 1Cycle moving condition of arms and legs, I acknowledge that a tool that makes blending possible under various moving conditions is necessary for a completed system.

• Journal of the Korean Magnetics Society
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• v.4 no.3
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• pp.201-207
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• 1994

RF 마그네트론 스퍼터링법으로 제작된 퍼멀로이(NiFe) 박막에 대하여 투입전력, 아르곤 압력, 바이어스 전압등의 스퍼터링 조건이 퍼멀로이 박막의 자기특성에 미치는 영향을 조사하였다. 투입전력에 따른 보자력의 변화는 300~400W에서 낮은 값을 지녔으며 아르곤 압력에 따른 변화는 1~5mTorr에서 낮은 값을 나타내었다. 스퍼터링 조건에 따른 최소의 보자력값은 400 W, 5mTorr 와 300 W, 2mTorr에서 각각 0.10 Oe를 나타내었고 최대의 투자율값은 400 W, 5mTorr에서 2800(1 MHz)을 나타내었다. 또한 저압의 스 퍼터링 압력에서 바이아스를 가할 경우 보자력은 이에 비례해서 오히려 증가하였다. 박막의 Ni 함량의 변화는 아르곤 압력이 증가함에 따라 점차적으로 감소하나 2~10mTorr 범위에서는 다시 증가하는 경향을 보였다. 내부응력은 아르곤 압력이 증가함에 따라 압축응력에서 인장응력으로 변하였으며 5mTorr에서 내 부응력이 거의 사라졌다.

• Journal of the Korean Institute of Telematics and Electronics D
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• v.34D no.12
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• pp.76-82
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• 1997

Chemical mechanical polishing (CMP) has become widely accepted for the planarization of multi-interconnect structures in semiconductor manufacturing. However, perfect planarization is not so easily ahieved because it depends on the pattern sensitivity, the large number of controllable process parameters, and the absence of a reliable process model, etc. In this paper, we realized the planarization of deposited oxide layers followed by metal (W) polishing as a replacement for tungsten etch-back process for via formation. Atomic force microscope (AFM) is used for the evaluation of pattern topography during CMP. As a result, AFM evaluation is very attractive compared to conventional methods for the measurment of planarity. mOreover, it will contribute to analyze planarization characteristics and establish CMP model.

• Korean Journal of Veterinary Research
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• v.20 no.1
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• pp.1-10
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• 1980

매추리 유래 가금 adenovirus인 QBV로 부터 CsCl을 사용한 균질밀도분배원심분리법으로 AAAV의 분리를 시도하였으며, 분리된 바이러스의 순수성을 전자현미경 및 혈청학적인 방법을 통하여 증명하였으며 순수 분리된 AAAV를 항원으로 사용한 혈청반응을 개발하였다. 즉, CsCl의 밀도 1.38 및 $1.42gm/cm^3$의 분획들은 순수한 AAAV이었으며 $1.42gm/cm^3$의 분획은 토끼에서 양성혈청제조용 면역원으로 1.38 및 $1.42gm/cm^3$의 분획은 혈청반응용 표준항원으로 사용하였다. AAAV 표준항원 및 가토 양성혈청계는 MDV, IBDV, ITV 및 "helper"인 가금 adenovirus와의 교차반응이 없었으며 혈청학적인 특이성이 인정되었다. 또한 상기 혈청학적 반응을 이용하여 AAAV의 동정은 물론 AAAV에 대한 닭의 항체검출을 가능하게 하였다.

• Proceedings of the Korean Information Science Society Conference
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• 2011.06d
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• pp.122-125
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• 2011

버퍼 오버플로우(buffer overflow) 취약점은 1988년 모리스 웜(Morris worm)을 통하여 널리 알려진 이후 이를 해결하기 위한 많은 연구들이 진행되었으며, 동시에 이를 이용한 공격 역시 끊임없이 이루어지고 있다. 기존의 버퍼 오버플로우 취약점에 대한 연구는 크게 컴파일러 및 라이브러리, 커널, 하드웨어 단계로 나눌 수 있다. 하지만 이러한 방법들은 다양한 한계를 가진다. 본 논문은 이러한 문제들을 해결하기 위하여 버퍼 오버플로우 취약점을 발생시키는 코드를 바이너리에서 직접 검색하고, 이를 패치하여 버퍼 오버플로우 취약점을 제거하는 BinaryReviser를 구현하였다.

• Proceedings of the Korea Information Processing Society Conference
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• 2023.05a
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• pp.360-362
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• 2023

건강정보 검색 요구가 증가하면서 다양한 건강정보 검색 서비스가 제공되고 있다. 하지만 최근의 건강정보 검색 서비스는 정형화 된 전문적인 의료정보와 그 해석을 제공하기 때문에 사용자는 이러한 정보를 스스로 이해하여 원하는 건강정보를 검색해야 한다. 사용자의 검색 피로를 줄이고 원하는 정보를 정확하게 얻을 수 있는 건강정보 검색 시스템 개발을 위하여 사용자의 비의료적 표현인 한국어 증상발화 데이터 구축이 선행되어야 한다. 이러한 데이터 구축은 많은 시간과 비용이 필요하기 때문에 이를 줄이기 위한 규칙기반 데이터 증강기법을 제시하고, 이를 활용하여 한국어 증상발화 데이터를 증강하였다. 증강된 데이터의 유효성을 보이기 위하여 KoBERT 기반의 증상분류 실험을 진행하였으며, 증강된 데이터가 그 전의 데이터보다 F1 스코어가 더 높음을 확인할 수 있었다.