• Journal of Chest Surgery
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• 제41권6호
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• pp.787-790
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• 2008

바렛식도는 식도선암의 전구 병변으로 알려져 있으나, 우리나라에서는 보고된 예가 극히 드물다. 본 원에서는 81세 남자에서 식도선암 진단 하에, 부분식도절제술 및 식도-위 단단문합술을 시행하였다. 절제된 조직의 병리검사에서 식도 선암종 주위의 배상세포를 동반한 장상피화생을 관찰할 수 있었다. 이에 문헌고찰과 함께 보고하는 바이다.

• Journal of Digestive Cancer Research
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• 제11권1호
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• pp.9-14
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• 2023

The prevalence of Barrett's esophagus is increasing in South Korea. Several strategies have been tried to prevent its progression to esophageal adenocarcinoma. It is questionable whether the strategies being tried in the West can be applied adequately in South Korea. However, despite the incidence of esophageal adenocarcinoma in the West, which is considerably higher than that in South Korea, the incidence of high-grade dysplasia/esophageal adenocarcinoma in population-based studies is as low as 0.23%/person-year. Therefore, in Korea, where the prevalence is lower than that, it is necessary to select high-risk groups more carefully for chemoprevention. The age of onset of gastroesophageal reflux disease-like symptoms at least once a week is related to the high-risk group rather than the presence or absence of chronic gastroesophageal reflux symptoms. The risk factors for esophageal adenocarcinoma include the patient's sex, age, smoking habit, and obesity. Proton pump inhibitors have a better preventive effect against esophageal adenocarcinoma compared to H2-receptor blockers, but their application to patients in Korea is limited due to the high number of individuals in need of treatment. Therefore, while considering the risk factors for the progression of esophageal adenocarcinoma, the administration of proton pump inhibitors should be considered for gastroesophageal reflux disease.