• Title/Summary/Keyword: 민감도 측정

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Performance Measurement of Siemens Inveon PET Scanner for Small Animal Imaging (소동물 영상을 위한 Siemens Inveon PET 스캐너의 성능평가)

  • Yu, A-Ram;Kim, Jin-Su;Kim, Kyeong-Min;Lee, Young-Sub;Kim, Jong-Guk;Woo, Sang-Keun;Park, Ji-Ae;Kim, Hee-Joung;Cheon, Gi-Jeong
    • Progress in Medical Physics
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    • v.21 no.2
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    • pp.145-152
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    • 2010
  • Inveon PET is a recently developed preclinical PET system for small animal. This study was conducted to measure the performance of Inveon PET as recommended by the NEMA NU 4-2008. We measured the spatial resolution, the sensitivity, the scatter fraction and the NECR using a F-18 source. A 3.432 ns coincidence window was used. A $1\;mm^3$ sized F-18 point source was used for the measurement of spatial resolution within an energy window of 350~625 keV. PET acquisition was performed to obtain the spatial resolution from the center to the 5 cm offset toward the edge of the transverse FOV. Sensitivity, scatter fraction, and NECR were measured within an energy window of 350~750 keV. For measuring the sensitivity, a F-18 line source (length: 12.7 cm) was used with concentric 5 aluminum tubes. For the acquisition of the scatter fraction and the NECR, two NEMA scatter phantoms (rat: 50 mm in diameter, 150 mm in length; mouse: 25 mm in diameter, 70 mm in length) were used and the data for 14 half-lives (25.6 hr) was obtained using the F-18 line source (rat: 316 MBq, mouse: 206 MBq). The spatial resolution of the F-18 point source was 1.53, 1.50 and 2.33 mm in the radial, tangential and axial directions, respectively. The volumetric resolution was $5.43\;mm^3$ in the center. The absolute sensitivity was 6.61%. The peak NECR was 486 kcps @121 MBq (rat phantom), and 1056 kcps @128 MBq (mouse phantom). The values of the scatter fraction were 20.59% and 7.93% in the rat and mouse phantoms, respectively. The performances of the Inveon animal PET scanner were measured in this study. This scanner will be useful for animal imaging.

A Study for Accuracy and Usefulness of Tympanic Membrane and Forehead Thermometers (고막 체온계와 이마 체온계의 정확성 및 유용성에 대한 연구)

  • Yun, Gi Wook;Lim, In Seok
    • Clinical and Experimental Pediatrics
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    • v.48 no.8
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    • pp.820-825
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    • 2005
  • Purpose : The presence and degree of fever in children is a useful indicator of illness. This project aimed to assess the accuracy and usefulness of infrared tympanic membrane(TM) & forehead feverscan thermometers for measuring children's temperatures. Methods : Data were obtained from 1,050 children with a median age of 4.5 years. They visited the pediatric clinics at Chung-Ang University Yongsan Hospital from January 2004 to December 2004. We measured body temperatures at axilla by mercury thermometer, at ear by infrared TM thermometer and at forehead by feverscan. Then we analyzed the correlation between these data. Results : Mercury and TM thermometer, and Mercury and forehead feverscan thermometer very well correlated with each others(P<0.05). And the sensitivity of infrared TM thermometer(right and left) to correctly identify febrile children was 81.1 percent and 82.4 percent, the positive predictive value to detect a fever was 81.8 percent and 73.6 percent. The sensitivity of forehead feverscan was 83.3 percent and the positive predictive value was 74.4 percent. Conclusion : The tympanic membrane temperature measured by the BRAUN IRT $3020^{(R)}$ and forehead arterial temperature measured by the HubDIC $DOTORY^{(R)}$ feverscan accurately reflects mercury axillary temperature, validly assesses the presence of fever in children, and is easy to use. The Braun IRT $3020^{(R)}$ & HubDIC $DOTORY^{(R)}$ therefore is an adequate tool to assess fever and may be used both in a clinical setting and for research purposes.

X-ray properties measurement of Flat panel Digital X-ray gas detector (평판형 디지털 엑스레이 가스 검출기의 엑스선 특성 측정기술에 관한 연구)

  • Yoon, Min-Seok;Cho, Sung-Ho;Oh, Kyung-Min;Jung, Suk-Hee;Nam, Sang-Hee;Park, Ji-Goon
    • Journal of the Korean Society of Radiology
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    • v.3 no.1
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    • pp.17-21
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    • 2009
  • The Recently, large area matrix-addressed image detectors are investigated for X-ray imaging with medical diagnostic and other applications. In this paper, a new flat panel gas detector for diagnostic X-ray imaging is proposed, and its characteristics are investigated. The research of flat panel gas detector is not exist at all. Because of difficulty to inject gas against to atmospheric pressure. So almost gas detector made by chamber shape. We made flat panel sample by display technique. (ex: PDP, Fed, etc.) The experimental measurements, the transparent electrodes, dielectric layer, and the MgO protection layer were formed in front glass. And, the X-ray phosphor layer and address electrodes are formed in the rare glass. The dark current, the x-ray sensitivity and linearity as a function of electric field were measured to investigate the electrical properties. From the results, the stabilized dark current density and the significant x-ray sensitivity were obtained. And the good linearity as a function of exposure dose was showed in wide diagnostic energy range. These results means that the passive matrix-addressed flat panel gas detector can be used for digital x-ray imaging.

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Characterization of Graphene Channel for $H_2$, $N_2$ Gas Sensor

  • Kim, Jin-Hwan;Park, Min-Ho;Jeong, Hye-Su;Park, Min-Jeong;Choe, Hyeon-Gwang;Jeon, Min-Hyeon
    • Proceedings of the Korean Vacuum Society Conference
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    • 2013.02a
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    • pp.212-212
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    • 2013
  • 본 연구에서는 최근 다양한 전자 소자로써의 연구가 진행되고 있는 그라핀을 실리콘 기판위에 전자빔 식각(Electron-Beam Lithography)을 이용하여 TLM (Transfer Length Method) 패턴을 형성하고 가스 유입이 가능한 진공 챔버를 가지는 Probe Station을 이용하여 I-V 변화를 측정함으로써, 그라핀을 가스 센서 소자로서의 가능성을 연구하였다. 우리는 기존의 광식각을 이용한 TLM 패턴 형성과 더불어 전자빔 식각(E-Beam Lithography: EBL)을 이용한 TLM 패턴을 형성하여 I-V를 측정하였는데, 전자빔을 이용한 TLM 패턴의 형성은 광식각을 이용한 방법에 비해 더 세밀하고 미세한 패턴을 형성하는 것이 가능하다. 이렇게 형성된 그라핀의 TLM패턴은 가스 유량 조절이 가능한 진공 챔버를 가지는 Probe Station을 이용하여 측정하게 되는데, 이 때 저진공 상태의 챔버 내로 N2, H2 두 종류의 가스를 각각 유량을 변화시키며 주입하고 그 변화를 측정하였다. 유입된 가스는 그라핀의 Dangling Bond에 결합됨으로써 그라핀의 전도도를 변화시키게 되고, 변화된 그라핀의 전도도에 따른 I-V 결과의 변화를 측정하여 이를 가스 센서로 사용할 수 있는지를 측정하였다. 또한 유입되는 가스의 유량 변화에 따른 I-V 결과의 변화량을 통하여 가스 센서의 민감도 또한 측정하였다.

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Research of Solid Propellant Electrostatic Sensitivity in Confinement (밀폐공간에서의 추진제 정전기 민감도에 대한 연구)

  • Choi, Jiyong;Lee, Seonjae;Kim, Jihong;Kim, Jinyong;Park, Euiyong
    • Journal of the Korean Society of Propulsion Engineers
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    • v.24 no.4
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    • pp.73-78
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    • 2020
  • The main reasons that ignite the propellant in the process of producing solid rocket motor are worker mistakes, wrong working process, mechanical defects, impact, friction, electrostatic and short circuits. In the past decades, many accidents have occurred in the process of producing solid rocket motor, accidents investigation have confirmed that the sensitivity of electrostatic is very high under specific condition. In this paper, we analyzed overseas accident cases and measured the sensitivity of electrostatic in the situation of confinement and pressure load by considering the manufacturing process. As a result of the test, the sensitivity of propellant was increased in the situation of confinement and pressure load and the propellant reacted more sensitively to electrostatic in the situation of confinement than pressure load.

Optimization of Parallel-Hole Collimator for Small Gamma Camera Based on Pixellated Crystal Array (배열형 섬광결정을 이용한 소형 감마카메라의 평행구멍형 조준기 최적화 연구)

  • Chung, Yong-Hyun;Beak, Cheol-Ha;Lee, Seung-Jae;Park, Jin-Hyung
    • Progress in Medical Physics
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    • v.19 no.4
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    • pp.291-297
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    • 2008
  • The purpose of this study is to optimize a parallel-hole collimator for small gamma camera having the pixellated crystal array and evaluate the effect of crystal-collimator misalignment on the image quality using a simulation tool GATE (Geant4 Application for Tomographic Emission). The spatial resolution and sensitivity were measured for the various size of hexagonal-hole and matched square-hole collimators with a Tc-99m point source and the uniformity of flood image was estimated as a function of the angle between crystal array and collimator by misalignment. The results showed that the spatial resolution and sensitivity were greatly improved by using the matched collimator and the uniformity was reduced by crystal-collimator misalignment.

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Classifying Host Susceptibility Using Porcine Circovirus Type 2 Viral Load and Antibody Titer (돼지 써코바이러스 2형 감염량과 항체가를 이용한 자돈의 저항성군 선발법)

  • Lim, Kyu-Sang;Lee, Eun-A;Lee, Kyung-Tai;Chun, Taehoon;Hong, Ki-Chang;Kim, Jun-Mo
    • Journal of Life Science
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    • v.27 no.3
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    • pp.283-288
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    • 2017
  • Porcine circovirus type 2 (PCV2) is a notorious and ubiquitous virus in the swine industry. The susceptibility of the host to PCV2 infection is considered to be one factor associated with the dynamics of PCV2. The objective of this study was to verify the criteria for host susceptibility to PCV2, using blood parameters of post-weaned pigs naturally infected with the virus. The PCV2 DNA viral load, antibody titer, and leukopenia characteristics were measured in the serum extracted from the pigs at the 10th week. We classified the pigs into high (>5.0), intermediate (3.0 to 5.0), and low (<3.0) groups on the basis of the PCV2 viral load (log copies/ml), or as positive (${\leq}0.50$) and negative (>0.50) groups on the basis of antibody titer (sample-to-negative corrected ratio). Moreover, using these two categorized parameters, we suggested the criteria for classification into the susceptible and resistant groups. Statistical analyses revealed that pigs in the susceptible group had a significantly higher viral load (p<0.001) and negative antibody titer (p<0.001), as well as significantly lower leukocyte counts (p=0.018) and lower amounts of several leukocyte components (p<0.05), than pigs in the resistant group. We concluded that the susceptible group could be considered to have PCV2-induced leukopenia. Therefore, we suggest that the combined classifications of viral loads and anti-PCV2 antibodies can be used to determine PCV2-induced leukopenia in the subclinical PCV2 infection of post-weaned pig populations.

Acoustic Sensitivity Analysis of a Ring-type Probe Based on a Fiber-optic Sagnac Interferometric Sensor (광섬유 사냑 간섭형 센서에 기반한 링형 탐촉자의 수중 음향 민감도 해석)

  • Lee, Yeon-Woo;Kwon, Hyu-Sang;Kwon, Il-Bum
    • Korean Journal of Optics and Photonics
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    • v.31 no.1
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    • pp.13-19
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    • 2020
  • To measure underwater acoustics using a fiber-optic Sagnac interferometric sensor, the sensitivities of ring-type probes are investigated by theoretical and experimental studies. A ring-type probe was fabricated by packaging a single-mode fiber wound around an acrylate cylinder of diameter 5 cm with epoxy bond. The probes were prepared as A-type, which was packaged with 46.84 m of sensing optical fiber, and B-type, which was packaged with 112.22 m of sensing fiber. The underwater acoustic test was performed at frequencies of 50, 70, and 90 kHz, and over a range of acoustic pressure of 20-100 Pa, to study the sensitivity. A commercial acoustic generator was located 1 m from the acoustic sensor, such as the ring-type probe or a commercial acoustic sensor. From the experimental test, the acoustic sensitivity of the ring-type probe had different values due to acoustic frequencies, unlike the theoretical prediction. Therefore, the experimental sensitivities were averaged for comparison to the theoretical values. These averaged sensitivities are 25.48 × 10-5 rad/Pa for the A-type probe and 60.79 × 10-5 rad/Pa for the B-type probe. The correction coefficient of Young's modulus c was determined to be 0.35.

The effect of the boss and mass on the sensitivity of the piezoresistive sensor (압저항 센서에서 보스와 매스가 센서 민감도에 미치는 영향)

  • Shim, Jae-Joon;Lee, Sung-Wook;Han, Dong-Seop;Kim, Tae-Hyung;Han, Geun-Jo
    • Proceedings of the Korean Institute of Navigation and Port Research Conference
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    • v.29 no.1
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    • pp.405-410
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    • 2005
  • In these days, the piezoresistive material has been applied to various sensors in order to measure the change of physical quantities. But the relationship between the sensitivity of a sensor and the position and size of piezoresistor has rarely been studied. Therefore, this paper was focused on the distribution of the resistance change ratio on the diaphragm and bridge surface where piezoresistor would be formed, and proposed the proper size and position of piezoresistor with which the sensitivity of sensor was increased. As the width of mass and boss was increased, the distance between piezoresistors was closed and the maximum value of resistance change ratio was decreased by the increase of the structure stiffness.

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LORETA analysis of EEG responding to positive/negative emotional stimuli for different sensitivities of behavioral activation and inhibition systems (긍/부정 감성자극에 대한 행동활성화체계 및 행동억제체계 민감도에 따른 뇌파의 LORETA 분석)

  • Kim Wuon-Shik;Jin Seung-Hyun
    • Science of Emotion and Sensibility
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    • v.8 no.4
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    • pp.403-413
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    • 2005
  • The purpose of the present study was to investigate the responses to positive/negative emotional stimuli for the different sensitivities of behavioral activation system (BAS) and behavioral inhibition system (BIS). We recorded If-channel EEG data for 8 BAS sensitive subjects an48 BIS sensitive subjects. EEGs were analyzed with LORETA (Low-resolution electromagnetic tomography) From scalp-recorded electrical potential distribution, LORETA computes the three-dimensional intracerebral distributions of current density for specified EEG frequency bands. hs results , significant differences between the BAS sensitive group ant the BIS sensitive group appeared LORETA alpha activities over the prefrontal lobe and the cingulate gyrus. Prefrontal regions and limbic system including cingulate gyrus are involved in emotional processing. Moreover, subjects with the high BAS sensitivity. responded more sensitively to the positive stimulation than subjects with the high BIS sensitivity. Therefore, our results suggest the possibility of correlation between BAS/BIS sensitivity and positive/negative emotional stimuli.

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