• The Korean Journal of Rheology
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• v.4 no.1
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• pp.25-34
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• 1992

저속으로 낙하하는 원통형 미소체의 유체역학적 거동에 대하여 점탄성 유체의 비 뉴우튼 성질의 영향에 관해서 연구가 수행되었다. 원통형 미소체의 직경 및 직경에 대한 길 이의 비 (Aspect Ratio)의 영향에 관해서도 또한 고찰하였으며 본 실험에서는 뉴우튼 유체 로서 99.5%의 글리세린용액과 점탄성 유체로서 1,000 wppm 의 polyacyla-mide(Separan AP-273) 수용액이 각각 사용되었다. 낙하하는 미소체의 Aspect Ratio가 증가할수록 무차원 최종속도는 뉴우튼 유체내에서 보다 점탄성 유체내에서 그증가속도가 더욱 커짐을 보였다. 뉴우튼 유체 내에서 낙하하는 원통형 미소체의 마찰저항 계수는 실험데이타로부터 계산된 값과 이론치가 비교적 잘일치하나 점탄성 유체에 관한 마찰저항 계수는 본 실험의 결과치와 무한히 긴 원통형 미소체에 대한 기존연구의 이론값과는 상당한 차이가 있음을 알수 있었 다, 이는 점탄성 유체내에서 수직으로 낙하하는 원통형 미소체의 저항계수가 k(즉 용기의 직경에 대한 미소체 직경의 비), power-law index 레이놀즈수 뿐아니라 aspect ratio를 포함 하는 새로운 관계식이 도출되어야 함을 분명히 보여주고 있다.

• Transactions of the Korean Society of Mechanical Engineers B
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• v.34 no.3
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• pp.251-258
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• 2010

This paper presents the technology for the design, fabrication, and characterization of a microfluidic system interface (MSI); the purpose of this technology is to enable the integration of complex microfluidic systems. The MSI technology can be applied in a simple manner for realizing complex arrangements of microfluidic interconnects, integrated microvalves for fluid control, and optical windows for on-chip optical processes. A microfluidic system for the preparation of genetic samples was used as the test vehicle to prove the effectiveness of the MSI technology for packaging complex microfluidic systems with multiple functionalities. The miniaturized genetic sample preparation system comprised several functional compartments, including compartments for cell purification, cell separation, cell lysis, solid-phase DNA extraction, polymerase chain reaction, and capillary electrophoresis. Additionally, the functional operation of the solid-phase extraction and PCR thermocycling compartments was demonstrated by using the MSI.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.30 no.4 s.247
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• pp.373-378
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• 2006

We present the design, fabrication, and characterization of a multi-chip microelectrofluidic bench, achieving both electrical and fluidic interconnections with a simple, low-loss and low-temperature electrofluidic interconnection method. We design 4-chip microelectrofluidic bench, having three electrical pads and two fluidic I/O ports. Each device chip, having three electrical interconnections and a pair of two fluidic I/O interconnections, can be assembled to the microelectofluidic bench with electrical and fluidic interconnections. In the fluidic and electrical characterization, we measure the average pressure drop of $13.6{\sim}125.4$ Pa/mm with the nonlinearity of 3.1 % for the flow-rates of $10{\sim}100{\mu}l/min$ in the fluidic line. The pressure drop per fluidic interconnection is measured as 0.19kPa. Experimentally, there are no significant differences in pressure drops between straight channels and elbow channels. The measured average electrical resistance is $0.26{\Omega}/mm$ in the electrical line. The electrical resistance per each electrical interconnection is measured as $0.64{\Omega}$. Mechanically, the maximum pressure, where the microelectrofluidic bench endures, reaches up to $115{\pm}11kPa$.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.36 no.5
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• pp.475-479
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• 2012

We present a novel polymer fabrication process involving direct UV patterning of a hyperbranched polymer, AEO3000. Compared to PDMS, which is the most widely used polymer in bioMEMS devices, the present polymer has advantages with regard to electrode integration and fast fabrication. We designed a four-chip microelectrofluidic bench having three electrical pads and two fluidic I/O ports. We integrated a microfluidic mixer and a cell separator on the bench to characterize the interconnection performance and sample manipulation. Electrical and fluidic characterization of the microfluidic bench was performed. The measured electrical contact resistance was $0.75{\pm}0.44{\Omega}$, which is small enough for electrical applications, and the pressure drop was 8.3 kPa, which was 39.3% of the value in the tubing method. By performing yeast mixing and a separation test in the integrated module on the bench, we successfully showed that the interconnected chips could be used for bio-sample manipulation.

• Proceedings of the KSME Conference
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• 2001.11b
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• pp.400-404
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• 2001

A micro-PIV(particle image velocimetry) measurement has been conducted to investigate flow fields in such microfluidic devices as microchannels and micronozzle. The present study employs a state-of-art micro-PIV system which consists of epi-fluorescence microscope, 620nm diameter fluorescent seed particles and an 8-bit megapixel CCD camera. Velocity vector fields with a resolution of $6.7\times6.7{\mu}m$ has been obtained, and the attention has been paid on the effect of varying measurement conditions of particle diameter and particle concentration on the resulting PIV results. In this study, the microfluidic elements were fabricated on plastic chips by means of MEMS processes and a subsequent molding process. Flow fields in a variety of microchannels as well as micronozzle have been investigated.

• Journal of computational fluids engineering
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• v.8 no.1
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• pp.38-43
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• 2003

• 유체기계공업학회:학술대회논문집
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• 2003.12a
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• pp.107-114
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• 2003

The influence of property difference in refraction index on micro PIV measurement of two-fluid flow in a microchannel was analyzed. The difference of measurement planes in two fluids would bring misunderstanding of the physics. The objective-imaging system for two-fluid flow measurement was presented, and the condition for measurement of valid velocity profile across two-fluid interface was derived. A micro PIV experimental system was set up to measure two-fluid flow inside a Y-shape microchannel. Under the conditions, three cases of two-fluid flow of glycerol solutions at different concentration (${\phi}$), e.g., (${\phi}=0\;and\;{\phi}=0.2,\;{\phi}=0.1\;and\;{\phi}=0.5,\;{\phi}=0\;and\;{\phi}=0.6$, were measured. Close agreement of experimental and numerical results was found.

• Proceedings of the Korean Society of Propulsion Engineers Conference
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• 2006.11a
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• pp.15-18
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• 2006

Recently, experimental visualization of microscale fluid transport has attacted considerable attention in designing microelectromechanical systems. Fluid-surface interactions on hydrophobic and hydrophilic surfaces can play a key role in passively controlling microfluidics. Here we investigate the slip boundary condition depending on the surface characteristics; hydrophilic, hydrophobic wettabilities. Using the micro-PIV, velocity profiles are measured in the glass (hydrophilic), PDMS (hydrophobic) microchannels.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.32 no.12
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• pp.1102-1106
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• 2008

Microfluidics deals with the behavior, precise control and manipulation of fluids at a micro scale. It has become increasingly prevalent in various applications such as biomedical applications (diagnostics, therapeutics, and cell/tissue engineering), inkjet head, and fuel cells etc. The issue of inspection and characterization of microfluidics has emerged as a major consideration in design, fabrication, and detection of microfluidic devices. In this paper, we characterize a diffusion based mixing in Y-microchannel using a fluorescent optical scanner based on a DVD pick-up module, which is widely used in optical storages. Using fluorescent dye, we measure the fluorescent intensity that represents the mixing patterns in Y-microchannel. We also compare these experimental results with computational fluid dynamics (CFD) simulation ones. It is shown that the proposed optical scanner can be used as an alternative measurement system with high performance and cost-effectiveness, compared to conventional optical tools such as epifluorescent microscopes using high resolution CCD camera and confocal microscopes with photomultiplier (PMT) detectors.

• Journal of the KSME
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• v.43 no.2
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• pp.38-42
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• 2003