• Title/Summary/Keyword: 미세 채널

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Simulation for the center-wavelength shift of interference filters by temperature variation (온도변화에 따른 간섭필터의 중심파장 이동의 전산모의)

  • 김성화;황보창권
    • Proceedings of the Optical Society of Korea Conference
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    • 2003.02a
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    • pp.80-81
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    • 2003
  • DWDM 필터와 같은 간섭필터는 밴드폭이 좁아지고 투과파장에 해당하는 채널의 수가 증가함에 따라 투과파장의 외부환경에 대한 안정성이 중요하다. 기존의 전자빔 증착법으로 증착된 유전체 다층박막은 일반적으로 미세기둥구조로 인해 낮은 조밀도를 가지기 때문에 외부의 습도나 온도 변화 등에 민감하다. 낮은 조밀도의 유전체 다층박막을 대기 중에 노출되었을 때, 대기 중의 습기가 기둥과 기둥 사이로 침투되어 유효굴절률의 증가로 인하여 박막의 광학두께가 증가하게 되고 결국 스펙트럼이 장파장으로 이동하게 된다. (중략)

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Microfluidic Preparation of Monodisperse Multiple Emulsion using Hydrodynamic Control (미세채널에서 수력학적 조절을 통한 단분산성 다중 액적 생성)

  • Kang, Sung-Min;Choi, Chang-Hyung;Hwang, Sora;Jung, Jae-Min;Lee, Chang-Soo
    • Korean Chemical Engineering Research
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    • v.50 no.4
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    • pp.733-737
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    • 2012
  • This study reports the microfluidic preparation of monodisperse multiple emulsions using hydrodynamic control. To generate multiple emulsions, we fabricate a microfluidic capillary device based on co-flowing stream without any surface modification of microchannels. Based on the system, we can successfully generate multiple emulsions (W/O/W) using water containing 0.5 wt% Tween 20, n-hexadecane with 5 wt% Span 80, and 10 wt% poly (vinyl alcohol) (PVA) aqueous solution, respectively. Furthermore, we control the number of inner droplets by modulation of flow rate of inner fluid at fixed flow rate of middle and outer fluid. The multiple emulsions having precisely controlled inner droplets' size and number can be applicable for multiple chemical reactions as an isolated microreactor.

Detection Property of Red Blood Cell-Magnetic Beads Using Micro Coil-Channeland GMR-SV Device (마이크로 코일-채널과 GMR-SV 소자를 이용한 적혈구-자성비드 검출 특성연구)

  • Park, Ji-Soo;Kim, Nu-Ri;Jung, Hyun-Jun;Lee, Sang-Suk
    • Journal of the Korean Magnetics Society
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    • v.25 no.1
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    • pp.16-21
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    • 2015
  • The micro device, coil, and channel for the biosensor integrated with the GMR-SV device based on the antiferromagnetic IrMn layer was fabricated by the light lithography process. When RBCs coupled with several magnetic beads with a diameter of $1{\mu}m$ passed on the micro channel, the movement of $RBC+{\mu}Beads$ is controlled by the electrical AC input signal. The $RBC+{\mu}Beads$ having a micro-magnetic field captured above the GMR-SV device is changed as the output signals for detection status. From these results, the GMR-SV device having the width magnitude of a few micron size can be applied as the biosensor for the analysis of a new magnetic property as the membrane's deformation of RBC coupled to magnetic beads.

Development of Multiple Channel Measurement System for IC Socket (IC 소켓 검사용 다중 채널 측정 시스템 개발)

  • Gang, Sang-Il;Song, Sung-Yong;Yoon, Dal-Hwan
    • Journal of IKEEE
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    • v.25 no.2
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    • pp.315-321
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    • 2021
  • In this paper, we have developed the multiple channel measurement system for IC Socket Test. The one can test the current-voltage measurements for pitting the several device specification, which analyze the thin current from several ㎂ to 5A with very low resistor mΩ. The increasement of the IC socket channel with lead pitch under 0.25 mm be need to perform several functions, concurrently. The system to perform these functions be designed to integrate several SMU(source measure unit) on board. So, we can reduce the 2 minutes test time per channel point to 40 sec, with daisy chain test method. Using by graphic interface, I-V curve mode and data logging technologies, we can implement the test flow methods and can make economies the time and cost.

Alignment of Microbeads Using Spinning Helical Minichannel Cartridge (회전하는 나선형 미니채널 카트리지를 이용한 미세입자 정렬)

  • Kim, Subin;Prasad, Bibin;Kim, Jung Kyung
    • Journal of the Korean Society of Visualization
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    • v.14 no.3
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    • pp.38-45
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    • 2016
  • Separation of particles based on different sizes, detection of pathogenic bacteria and isolation of leukocytes from whole blood are typical applications of spiral or helical microchannels. The present study focuses on developing a CD4+ T-cell counting device for monitoring HIV/AIDS patients with the aid of a helical minichannel used for a sample cartridge. For the experiment, $10{\mu}m$ sized microbeads were used for visualization with a fluorescence imaging system. Alignment of microbeads was investigated in a stationary and spinning sample cartridge filled with glycerol-water mixtures of different densities. The helical minichannel was spun using a DC motor controlled by an Arduino board with a Bluetooth shield. It was found that when the sample cartridge was made stationary, no bead alignment was achieved for a medium with density (0% and 20% glycerol) lower than that of the beads, but when it was spun at 2000-3000 rpm for 1-4 min, an alignment was obtained at the top of the channel facilitating optical detection and enumeration of those microbeads. Since an alignment of microbeads was achieved for a medium with density as that of blood plasma, the same approach can be applied for aligning and counting CD4+ T-lymphocytes in whole blood samples collected from patients.

Particle Loss Reduction Technique Using Dielectrophoresis in Microfluidic Channel (유전영동을 이용한 미세유체채널 내부의 입자 손실 저감 기술)

  • Kang, Dong-Hyun;Kim, Min-Gu;Kim, Yong-Jun
    • Journal of Sensor Science and Technology
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    • v.20 no.5
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    • pp.357-362
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    • 2011
  • This paper demonstrates a novel electrodynamic technique to remove particles from the wall of microchannels. Dielectrohporesis(DEP) is generated by applying alternating electric potentials to the interdigitated electrodes integrated at the bottom of the micro-channel. The proposed technique is applied to a general microfluidic channel as a feasibility test. To examine the wall loss reduction efficiency, 10 ${\mu}m$ diameter Polystyrene latexes(PSL) were supplied to the inlet of the device. Then, the concentration of collected particles through devices was measured. In the experiment for 10 ${\mu}m$ diameter PSL particles, the concentration of the injected particles was $174.25{\times}10^4$ particles/ml. However, the concentration of collected particles at the outlet was $52.25{\times}10^4$ particles/ml. Only 30 % of particles had arrived at the outlet and 70 % of particles had adhered to the wall of the microfluidic channel. By applying alternating electric potentials from 0 to 20 $V_{pp}$ at 3 MHz, the concentration of injected particles was 135.00${\times}10^4$ particles/ml, the concentration of collected particles was increased as $105.25{\times}10^4$ particles/ml at 20 $V_{pp}$ at the outlet. When the electric potential was 20 $V_{pp}$, the particle loss was decreased by 39 % (initial loss: 70 %, loss at 20 Vpp: 31 %) with 10 ${\mu}m$ particle. The particle loss was decreased along to the incensement of electric potentials and the enlargement of the diameter of particles. According to these measured results, it was confirmed that the proposal of using DEP technique could be a good candidate for particle loss reduction in micro-particle processing chip application. Moreover, it is expected that the proposed technique could enhance performance of microfluidic and biochip devices.

Microfabrication of the ISFET Cartridge by empolying Nozzle system (노즐의 원리를 도입한 ISFET 소형 카트리지 제작)

  • Kim, Hyun-Soo;Lee, Young-Chul;Kim, Young-Jin;Cho, Byung-Woog;Sohn, Byung-Ki
    • Journal of Sensor Science and Technology
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    • v.8 no.4
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    • pp.320-326
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    • 1999
  • A small cartridge, with a nozzle system for washing off the dirt from the surfaces of sensing gates, was fabricated. The proposed nozzle structure was designed for cartridge by using the simulation tool of fluid (CFD-ACE). Whole size of the fabricated cartridge by using micromachining techniques is about $2.6\;cm{\times}1.5\;cm$, the size of the washing nozzle is $0.2\;mm{\times}0.6\;mm$ and its dead volume is only about $20\;{\mu}l$. A micro-reference electrode was achieved by employing a differential system with ISFETs/QRE (quasi-reference electrode)/REFET (reference field-effect transistor). Metal electrodes was deposited at both ends of blowing channel were used to check the presence of bubble in the microchannel. The pH-ISFET was inserted into the fabricated cartridge and the washing effect of the nozzle system in cartridge was invested.

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A Study on Single Cell Polarized Signals Using Polydimethylsiloxane-based Micropatterned Channel System (폴리디메틸실록산 기반 마이크로패턴 채널 시스템을 이용한 단일 세포의 극성 신호에 관한 연구)

  • Suh, Jung-Soo;Lee, Chanbin;Pan, Yijia;Wang, Yingxiao;Jung, Youngmi;Kim, Tae-Jin
    • Korean Chemical Engineering Research
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    • v.58 no.1
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    • pp.122-126
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    • 2020
  • In this study, we produced the micropatterned channel system using polydimethylsiloxane (PDMS) and micromolding in capillaries (MIMIC) technology and evaluated cellular polarity signals through high-resolved imaging at the single-cell level. In cells treated with platelet-derived growth factor (PDGF), three types of key signals in cell migration; phosphoinositide 3-kinase (PI3 K), Rac, and Actin, were strongly activated in the front area compared to the rear region, whereas myosin light chain (MLC) showed no notable activity in the front and rear areas. Our results will, therefore, provide important information and methodology for studying the correlation between cell polarity signals and cell migration under the newly defined microenvironment.