• Proceedings of the Korean Vacuum Society Conference
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• 2004.02a
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• pp.129-130
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• 2004

• Clean Technology
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• v.25 no.4
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• pp.283-288
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• 2019

Monodisperse microparticles has been particularly enabling for various applications in the encapsulation and delivery of pharmaceutical agents. The microfluidic devices are attractive candidates to produce highly uniform droplets that serve as templates to form monodisperse microparticles. The microfluidic devices that have micro-scale channel allow precise control of the balance between surface tension and viscous forces in two-phase flows. One of its essential abilities is to generate highly monodisperse droplets. In this paper, a microfluidic approach for preparing monodisperse polycaprolactone (PCL) microparticles is presented. The microfluidic devices that have a flow-focusing generator are manufactured by soft-lithography using polydimethylsiloxane (PDMS). The crucial factors in the droplet generation are the controllability of size and monodispersity of the microdroplets. For this, the volumetric flow rates of the dispersed phase of oil solution and the continuous phase of water to generate monodisperse droplets are optimized. As a result, the optimal flow condition for droplet dripping region that is able to generate uniform droplet is found. Furthermore, the droplets containing PCL polymer by solvent evaporation after collection of droplet from device is solidified to generate the microparticle. The particle size can be controlled by tuning the flow rate and the size of the microchannel. The monodispersity of the PCL particles is measured by a coefficient of variation (CV) below 5%.

• Transactions of the Korean Society of Mechanical Engineers B
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• v.34 no.1
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• pp.53-59
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• 2010

In this paper, we propose a novel chaotic micromixer of which mixing mechanism is based upon magnetohydrodynamic (MHD) multi-vortical flow generation in a simple straight microchannel. In the microchannel of the micromixer has electrodes patterned on two side walls and bottom wall. Lorentz forces are variously induced by changing applied voltages at the patterned electrodes in order to pump and mix conductive fluids in the microchannel. Three-dimensional computational fluid dynamics simulations were conduced to characterize mixing behaviors inside the MHD micromixer. The mixing efficiencies were also evaluated for the various flow conditions.

• Transactions of the Korean Society of Mechanical Engineers B
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• v.34 no.1
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• pp.61-66
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• 2010

In our previous work, 3-dimensional hydrodynamic focusing microfluidic device (3D-HFMD) has been developed with the help of locally increased aspect ratio of thickness to width without any horizontal separation wall. In this study, we have investigated 3-dimensional hydrodynamic focusing behaviors inside the 3D-HFMD according to the various geometric and flow conditions. The parametric study has been extensively carried out for the effects of geometric and flow conditions on 3-dimensional hydrodynamic focusing with both 3D-HFMD and previous microfluidic device design based on three-dimensional computational fluid dynamics (CFD) simulations. The CFD simulations suggested the proper design window of channel geometry and flow conditions.

• Transactions of the Korean Society of Mechanical Engineers B
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• v.34 no.7
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• pp.671-677
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• 2010

In the present study, we designed a microfluidic platform for generating monodisperse droplets with diameters ranging from hundreds of nanometers to several micrometers. To generate fine droplets, T-junction and flow-focusing geometry are integrated into the microfluidic channel. Relatively large aqueous droplets are generated at the upstream T-junction and transported to the flow-focusing geometry, where each droplet is broken into smaller droplets of the desired size by the action of pressure and viscous stress. In this configuration, the flow rate of the inner fluid can be made very low, and the ratio of the inner- and outer-fluid flow rates in the flow-focusing region can be made very high. It has been shown that the present microfluidic device can generate droplets with diameters of approximately $1\;{\mu}m$ (standard deviation: <3%).

• Proceedings of the SAREK Conference
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• 2008.11a
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• pp.269-274
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• 2008

The present study has been studied on a thermal and flow characteristic of the microchannel waterblock with flow distributions in each channels. Results of a numerical analysis using the CFX-11 are compared with results of an experiment. Numerical analysis and experiment are conducted under a heat transfer rate of 150W, inlet temperature of $20^{\circ}C$ and mass flow rates of $0.7{\sim}2.0\;kg$/min. Base temperature and pressure drop are investigated with standard deviations of mass flow rates in each channels of samples at 0.7 kg/min.

• Journal of the Korean Society of Visualization
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• v.1 no.1
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• pp.75-81
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• 2003

A custom micro-PIV optics assembly has been used to measure the flow fold inside a T-junction of a microchannel. The micro-PIV system consists of microscope objectives of various magnifications, a dichroic cube, and an 8-bit CCD camera. Fluorescent particles of diameters 620 nm have been used with a Nd:YAG laser and color filters. A programmable syringe pump with Teflon tubings were used to inject particle-seeded distilled water into the channel at flow rates of 2.0, 4.0, 6.0 mL/hr. The micro-channels are fabricated with PDMS with a silicon mold, then O$_{2}$ -ion bonded onto a slide glass. Results show differences in flow characteristics and resolution according to fluid injection rates, and magnifications, respectively. The results include PIV data with vector-to-vector distances of 2 $\mu$m with 32 pixel-square interrogation windows at 50$\%$ overlap.

• Journal of the Korean Society for Aeronautical & Space Sciences
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• v.32 no.8
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• pp.72-81
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• 2004

A Wind tunnel test for a high speed ground vehicle was conducted to investigate the aerodynamic interactions between the vehicle and a solid channel. The free stream velocity was 30m/see and Reynolds number per unit length was $3.1{\times}10^5/m$. Experimental devices such as a variable channel ground and guide way were used for the test. As the vehicle was close to the channel ground and guide way, lift was significantly increased, drag was slightly decreased and pitching moments were restricted to augment static stability. Using smoke-wire, flow visualization was made to confirm these results by comparing the channel and non-channel flow characteristics of the vehicle. Under the influence of the channel ground and guide way, the flow beneath the vehicle was not discharged outside wing end plates, which was the major reason of the increase in lift of the vehicle.

• 순환기질환의공학회:학술대회논문집
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• 2005.12a
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• pp.37-38
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• 2005

• Proceedings of the SAREK Conference
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• 2004.06a
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• pp.23-23
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• 2004