• Journal of the Korean Society of Visualization
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• v.13 no.2
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• pp.22-27
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• 2015

Caenorhabditis elegans (C.elegans) has various interesting behavioral properties, such as chemotaxis, thermotaxis, and electrotaxis. However, most previous research were only focused on single-stimulus for studying its behavioral properties. In this paper, we propose a simple and effective device for analyzing the behavior of C.elegans with combined stimuli, electric field and temperature. We compared and analyzed wild type worms (N2) and four mutant worms (tax-4, ttx-7, unc-54, unc-6). We analyzed the reaction of worms to certain stimulus and identified that this device is effective to apply a combined stimulus.

• Proceedings of the KIEE Conference
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• 2007.07a
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• pp.1546-1547
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• 2007

휴대용 면역진단 시스템을 구현하기 위하여 설계된 공기주입기로 구동되는 랩온어칩 내의 유체 유동을 컴퓨터 시뮬레이션을 통하여 해석하고, 문제점을 보완할 수 있는 구조로 랩온어칩을 재설계하였다. 공기주입기에서 흘러나오는 공기를 이용해 완충액 저장고 내에 있는 완충액을 토출시킬 때 다량의 기포가 발생함을 시뮬레이션 결과를 통해 알 수 있었다. 완충액 저장고의 내부에 계단형 구조를 삽입함으로서 완충액 이송 시 형성되는 기포를 상당히 억제할 수 있었다. 또한 계단형 구조는 유선을 역행 방지판 쪽으로 분산시켜 역행 방지판의 효율을 높일 것이다.

• Transactions of the Korean Society of Mechanical Engineers A
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• v.33 no.7
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• pp.673-680
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• 2009

In this study, die cooling system using the nitrogen gas has been applied to hot aluminum extrusion process for refining grains and reducing of grain growth. Computational fluid dynamics(CFD) has been carried out to evaluate die cooling effect by nitrogen gas, and the results of CFD have been used to FE-simulation for the prediction of the extrudate temperature in hot extrusion process. Experimental hot extrusion has been performed to observe microstructure and to measure temperature of extrudate. The results of FE-Simulation have been good agreement with those of experiment. Finally, process condition of hot extrusion can be established to reduce grain growth of Al6061 through the experiment.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.19 no.3
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• pp.679-686
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• 2018

A new dust cleaning vehicle is needed to remove fine and ultra-fine particulate matter in subway tunnels. Therefore, the recently developed tunnel cleaning vehicle is equipped with an efficient suction system and cyclone-based prefilter to handle ultra-fine particles. To treat various sizes of particulate matter with an underbody suction system, this paper proposes a cyclone-based prefilter in the suction system and validates the dust removal efficiency through Computational Fluid Dynamics (CFD) analysis using ANSYS FLUENT. Using the created surface and volume mesh, various particle sizes, materials, and fan flow rates, the particles were tracked in the flow with a discrete phase model. As a result, the dust cleaning vehicle at a normal operational speed of 5km/h requires at least a fan flow rate of $1500m^3/min$ and 100mm of suction inlet height from the tunnel track floor. Those suction modules and cyclone-based prefilters in the dust cleaning vehicle reduces the dust accumulation load of the electric precipitator and helps remove the accumulated fine and ultra-fine dust in the subway tunnel.

• Transactions of the Korean Society for Noise and Vibration Engineering
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• v.27 no.1
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• pp.28-35
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• 2017

Recently, conventional hydraulic car lift systems face the technological limitations due to a lack of height control. The demand for height controllability is required in many tasks such as wheel alignment, and requires compensation for the structural deformation of the lift caused by irregular load distribution. In order to resolve this limitation of the conventional car lift, in this work, a new type of a hydraulic vehicle lift using a magneto-rheological (MR) valve system is proposed and analyzed. Firstly, the dynamic model of vehicle lift is formulated to evaluate control performance; subsequently, an MR valve is designed to obtain the desired pressure drop required in the car lift. Next, a proportional-integral-derivative (PID) controller is formulated to achieve accurate control of the lifting height and then computer simulations are undertaken to show accurate height control performances of the proposed new car lift system.

• Journal of the Korean Society for Marine Environment & Energy
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• v.6 no.1
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• pp.60-67
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• 2003

Flow around an oscillating circular cylinder was experimentally investigated. With varying Keulegen-Carpenter(KC) number from 10 to 30 the flow field with vortex sheddings and the related hydrodynamic fortes exerting on the cylinder were measured. A newly developed PW(paricle image velocimetry) successfully captured the complex vortical flows varying with the KC number and the flow patterns were 'traverse street', 'single pairing' and 'double pairing' of vortices with increasing KC number, At a certain KC number range the lift force undergoes a transition showing little periodicity due to surrounding complicated shedded vortices.

• Journal of the Semiconductor & Display Technology
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• v.16 no.3
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• pp.41-46
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• 2017

This study aims to select suitable co-solvents and to obtain optimal process conditions in order to improve process efficiency and productivity through experimental results obtained under various experimental conditions for the etching and rinsing process using liquid carbon dioxide and supercritical carbon dioxide. Acetone was confirmed to be effective through basic experiments and used as the etching solution for MEMS-wafer etching in this study. In the case of using liquid carbon dioxide as the solvent and acetone as the etching solution, these two components were not mixed well and showed a phase separation. Liquid carbon dioxide in the lower layer interfered with contact between acetone and Mems-wafer during etching, and the results after rinsing and drying were not good. Based on the results obtained under various experimental conditions, the optimum process for treating MEMS-wafer using supercritical CO2 as the solvent, acetone as the etching solution, and methanol as the rinsing solution was set up, and MEMS-wafer without stiction can be obtained by continuous etching, rinsing and drying process. In addition, the amount of the etching solution (acetone) and the cleaning liquid (methanol) compared to the initial experimental values can be greatly reduced through optimization of process conditions.

• Journal of the Society of Cosmetic Scientists of Korea
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• v.50 no.2
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• pp.119-129
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• 2024

The cutaneous lymphatic system in humans plays a crucial role in draining interstitial fluid and activating the immune system. Environmental factors, such as ultraviolet light and natural aging, often affect structural changes of such lymphatic vessels, causing skin dysfunction. However, some limitations still exist because of no alternatives to animal testing. To better understand the skin lymphatic system, a biomimetic microfluidic platform, skin-lymph-on-a-chip, was fabricated to develop a novel in vitro skin lymphatic model of humans and to investigate the molecular and physiological changes involved in lymphangiogenesis, the formation of lymphatic vessels. Briefly, the platform involved co-culturing differentiated primary normal human epidermal keratinocytes (NHEKs) and dermal lymphatic endothelial cells (HDLECs) in vitro. Based on our system, Lymphanax^TM, which is a condensed Panax ginseng root extract obtained through thermal conversion for 21 days, was applied to evaluate the lymphangiogenic effect, and the changes in molecular factors were analyzed using a deep-learning-based algorithm. Lymphanax^TM promoted healthy lymphangiogenesis in skin-lymphon-a-chip and indirectly affected HDELCs as its components rarely penetrated differentiated NHEKs in the chip. Overall, this study provides a new perspective on Lymphanax^TM and its effects using an innovative in vitro system.

• Journal of Aerospace System Engineering
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• v.12 no.6
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• pp.1-8
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• 2018

ACF, which is used for the transparent electrode film is manufactured by the thermocompression method with conductive particles. However, the method has disadvantages since there are many wasted materials and the process is complex. To overcome the demerits of the conventional method, EHD printing technology with conductive particles ink is proposed. The line thickness of patterning is influenced by the characteristics of the inks and the printing conditions. Therefore, it is salient to find the most conducive conditions for the micro patterning. In this paper, the ink with conductive particles was manufactured, and the patterning results were obtained by varying the nozzle thickness and the flow rate. The electrical conductivity according to the ejection of the particles ink is obtained.

• Journal of the Korean Society of Visualization
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• v.14 no.1
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• pp.57-61
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• 2016

We report a finding of fast(exceeding 2,000 K/s) heating of polydimethylsiloxane(PDMS), one of the most commonly-used microchannel materials, under cyclic loadings at high(~MHz) frequencies. A microheater was created based on the finding. The heating mechanism utilized vibration damping of sound waves, which were generated and precisely manipulated using a conventional surface acoustic wave(SAW) microfluidic system, in PDMS. The penetration depths were measured to range from $210{\mu}m$ to $1290{\mu}m$, enough to cover most microchannel heights in microfluidic systems. The energy conversion efficiency was SAW frequency-dependent and measured to be the highest at around 30 MHz. Independent actuation of each interdigital transducer(IDT) enabled independent manipulation of SAWs, permitting spatiotemporal control of temperature on the microchip. All the advantages of this microheater facilitated a two-step continuous flow polymerase chain reaction(CFPCR) to achieve the billion-fold amplification of a 134 bp DNA amplicon in less than 3 min. In addition, a technique was developed for establishing dynamic free-form temperature gradients(TGs) in PDMS as well as in gases in contact with the PDMS.