• Proceedings of the Earthquake Engineering Society of Korea Conference
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• 2000.10a
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• pp.496-500
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• 2000

대형 구조물의 진동제어를 위하여 MR 유체 댐퍼를 사용한 반능동 제어기법에 대하여 연구하였다. 기존에 많이 사용되고 있는 수동제어기법은 일단 제어장치를 설치한 후에는 구조물에 실제로 작용하고 있는 외부 하중의 현재 특성에 대해서 적절히 반응할 수 없다는 제한을 가지고 있으며, 이를 극복하기 위하여 연구되어온 능동제어기법은 구조물이 진동을 감소시키기 위하여 구조물에 직접적으로 가해지는 커다란 제어력을 요구하며, 이로 인해 경우에 따라서는 불안정한 상태가 유발될 수도 있다는 점이 단점으로 지적되고 있다. 최근에 Spencer 등은 반능동 제어기법을 제안하였는데, 이는 수동제어장치의 제어특성을 On-Line 으로 조절하는 방식으로서 제어 가능한 수동제어기법으로도 불리운다. 구조물의 진동제어에 필요한 제어력이, 특수한 제어기구에서 발생되는 인위적인 힘이 아니라, 적절한 구조부재에서 발생되는 자연적인 부재력이므로, 무엇보다 강인하고 신뢰할 수 있는 제어기법이며, 이때 제어장치의 구조적 특성을, 측정된 구조물의 응답에 맞추어 적절히 조절함으로써 다양한 외부하중에 대해 보다 효율적인 제어가 이루어질 수 있도록 한 방법이다. 반능동제어를 위한 제어기로서는 Variable Orifice Dampers, Friction Controllable Isolators, Variable Stiffness Devices, Electro-Rheological (ER) Fluid Damper, Magneto-Rheological(MR) Fluid Damper등이 제안되고 있으며, 본 논문에서는 반응속도가 빠르고, 적은 파워만을 요구하며, 커다란 제어력을 낼 수 있는 MR Damper를 사용하여 지진하중을 받는 구조물의 반능동 제어게 대하여 연구하였다. MR Damper의 특성이 비선형이므로 이에 적합한 Sliding Mode Fuzzy Control(SMFC)기법을 사용하였으며 이때 SMFC 의 최적 설계를 위하여 Genetic Algorithm을 적용하였다. 제안된 제어기법의 실제 적용성을 검증하기 위하여 기존이 제어결과와 비교 검토하였으며, 그 결과로부터 MR Damper를 사용한 반능동 제어기법이 구조물의 진동제어에 매우 효과적임을 확인할 수 있었다.

• Journal of Life Science
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• v.24 no.1
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• pp.8-13
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• 2014

The moringa (Moringa oleifera Lam.) plant is used as food and as an anti-allergic agent. In this study, we studied the inhibitory effect of moringa root extract on the expression of PMA-induced matrix metalloproteinase-9 (MMP-9), which is the main factor implicated in the invasion and metastasis of cancer cells in MCF-7 cells. At first, various moringa extracts were examined in the MCF-7 cells. Both moringa root extract and leaf extracts inhibited PMA-induced MMP-9 activity, but the root extract suppressed PMA-induced MMP-9 activity to a greater extent than the leaf extract. The moringa root extract also inhibited PMA-induced MMP-9 protein expression and cell invasion. According to RT-PCR, the treatment of the MCF-7 cells with moringa root extract decreased levels of PMA-induced MMP-9 mRNA expression, but not the expression of TIMP-1 and -2, indicating that moringa root extract prevents the transcription of MMP-9 in response to PMA. In addition, moringa root extract specifically suppressed the phosphorylation of ERK/JNK, but not p38. We suggest that moringa root extract abolishes MMP-9 activity/expression through ERK/JNK. In conclusion, moringa root extract suppressed PMA-induced MMP-9 activity/expression by inhibiting the phosphorylation of ERK/JNK in MCF-7 cells. These results indicate that moringa root extract may be a potential antimetastatic and anti-invasive agent. Future clinical research is needed on the anticancer properties of moringa root extract.

• The Korean Journal of Zoology
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• v.38 no.3
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• pp.433-441
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• 1995

Mammary tissue-specificity of the caprine $\beta$-lactoglobulin promoter appears to be secured by repression in non-expressing cells. In order to identify the mechanism of the negative regulation, the upstream promoter sequence of the caprine $\beta$-lactoglobulin gene was analyzed in detail. The repression was mediated by the upstream flanking sequence from -47O to -205. The sequence could repress the promoter activity of $\beta$-lactoglobulin in either orientation. The effect of the putative negative regulation element of caprine $\beta$-lactoglobulin on heterlogous promoters, however, varied: the promoter activity of herpes simplex virus thimidine kinase was either repressed or activated by the sequence depending on its orientation, while the SV4O early promoter was activated rather than repressed. The regulatory sequence involving the putative negative regulatory element was strongly shifted with the nuclear extract from non-mammary HeLa and CV-1 cells, while only weak shift was observed with that of mammary HC11 cells. Such correlation between repression and factor binding suggests that the protected regions in foot-printing assay may be the negative regulatory elements of $\beta$-lactoalobulin that serve tissue-specific repression.

• The Journal of the Korean bone and joint tumor society
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• v.12 no.2
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• pp.141-147
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• 2006

In 1996, a nine-year-old girl was treated with recycling autograft after wide resection of the distal femoral osteosarcoma. The leg lengthening and revision with growing tumor prosthesis were performed due to limb leg discrepancy and epiphyseal problem. However, deep infection developed after operation, and a temporary spacer with cement and Ender nail was inserted. After infection was controlled completely, the final leg lengthening was performed with mono-external fixator for limb length discrepancy (10 cm). Lastly, Tumor prosthesis was reinserted to preserve the joint function.

• Monthly Korean Chicken
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• v.19 no.10
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• pp.110-113
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• 2013

• Water for future
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• v.28 no.5
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• pp.39-45
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• 1995

• Water for future
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• v.30 no.1
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• pp.32-38
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• 1997

• 베이커리
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• no.4 s.405
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• pp.170-173
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• 2002

• Water for future
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• v.32 no.6
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• pp.96-101
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• 1999

• Water for future
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• v.4 no.2
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• pp.50-58
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• 1971