• Journal of Chest Surgery
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• v.30 no.2
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• pp.195-199
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• 1997

From Dec. 1992 to Dec. 1995, 20 patients with atherosclerotic occlusive disease in the lower extremities underwent arter al bypass surgery. The age of the patients ranged between 46 and 77 years(mean .60.8 years) and the most prevalent incidence was in the 7th decades. The mean follow up period was 18.8 months ranging from 4 to 36 months. Associated diseases were diabetus mellitus(25%), hypertension (35%), cerebrovascular accident(25%), and acute myocardial infarction(5%). Disabling intermittent claudifcation(35%), resting pain(20%) or ischemic gangrene(or ulceration)(45%) were operative indications. Aorto-bifemoral bypass in 4 cases, aorto-single femoral bypass in 2 cases, Aorto-bifemoral bypass and femoropopliteal bypass in 3 cases, aorto-single femoral bypass and femoropopliteal bypass in 1 case, femoropopliteal bypass in 4 cases, femorotibial bypass in 1 case, popliteotibial bypass 4 cases and femorofemoral bypass in 1 case were the surgical approches. Early thrombosis(2 cases) and wound infection(2 case) were main complication. Postoperative complication rate was 20% . Postoperative patency rates re 92.6% at 6 months, 84.2% at 1 year, 75.4% at 2 years and 69.4% at 3 years.

• Childhood Kidney Diseases
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• v.6 no.1
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• pp.56-60
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• 2002

Purpose Streptococcus pneumoniae is a major pathogen in both adults and children, causing significant morbidity and mortality In patients with nephrotic syndrome, Streptococcus pneumoniae is a major cause of spontaneous peritonitis, and the increasing incidence of penicillin-resistance strain facilitates the development of effective vaccine. The limitation of current pneumococcal polysaccharide vaccine prompted development of polysaccharide- protein conjugate vaccine. Methods: We reviewed the medical record of total 225 steroid responsive nephrotic patients to ascertain the effectiveness of 23- valent pneumococcal polysaccharide vaccine. Results. Twenty- eight patients have developed peritonitis during the courses, and 7 of those have recurrent peritonitis. Fifty- five patients were vaccinated and followed- up for 1- 108 months (mean 38.5 months), and during the follow- up period, pneumococcus related peritonitis was not detected. Vaccine- related relapse of nephrotic syndrome w as absent. Conclusion: In spite of the non- consensus about the efficacy of PPV23, clinically it benefits, and until the clinical trial of PCV7 is completed, PPV23 will be recommended. (J Korean Soc Pediatr Nephrol 2002;6: 56-60)

• Journal of the Korea Academia-Industrial cooperation Society
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• v.21 no.7
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• pp.645-655
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• 2020

This is a descriptive study investigating the relationships between sexual function, depression, and sleep quality in male hemodialysis patients. The participants of this study consisted of 134 outpatients who were diagnosed with end stage chronic kidney disease and who had undergone hemodialysis. The data were collected from June 10, 2019, to October 30, 2019. The collected data were then analyzed using descriptive statistics, the mean from independent sample t-tests, one-way analysis of variance (ANOVA), the Scheffe test, and Pearson's correlation coefficient using SPSS version 21.0. The lower the overall satisfaction, the lower the sexual function and the higher the degree of depression (r=.-19, p=.028). The greater the depression, the lower the quality of sleep (r=.60, p<.001). This study shows it is necessary to develop a program including symptom management to reduce depression in male hemodialysis patients. When developing nursing interventions to improve sexual function and quality of sleep, it will be necessary to develop a program that includes people who help the subjects.

• Proceedings of the KAIS Fall Conference
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• 2011.05b
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• pp.1057-1060
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• 2011

본 연구는 건강신념모형의 주요 변수와 고지혈증 환자의 건강행태와의 관계를 파악하여 고지혈증 환자의 건강행태를 촉진하고 더 나아가 만성질환 보건사업 및 교육프로그램을 계획하는데 기초 자료를 제공하고자 시도되었다. 자료는 2009년 07월부터 2010년 9월까지 총콜레스테롤이 240mg/dl 이상이고, 중성지방이 200mg/dl 이상으로 고지혈증을 진단받은 20세 이상의 성인 남녀 146명을 대상으로 구조화된 설문지를 이용하여 조사하였으며, SPSS WIN(14.0 한글판) 프로그램을 이용하여 Chronbach's alpha의 신뢰성 분석, 요인분석, 단변량 및 다변량 분석을 시행하였다. 본 연구의 결과는 다음과 같다. 첫째, 본 연구에서는 LDL-cholesterol, HDL-cholesterol, TG에 대한 인지수준 중 TG에 대한 인지가 가장 높았고, 3가지 모두를 인지한 경우는 28.08%였다. 또한 9가지 항목에 대한 고지혈증 지식수준은 9점 만점에 평균 6.51이었으며, 지식수준이 높을수록 건강행태수준도 높았다. 둘째, 요인분석을 통하여 10개의 건강행태를 2개 요인으로 재분류 하였다. 그 결과, 건강행태 요인 1은 '식이, 운동 습관 및 고지혈증 검사 및 관련 검사요인', 건강행태 요인 2는 '흡연, 음주 습관 및 고지혈증 치료 관련 요인'이었다. 건강행태 요인1에 유의한 관련성이 있는 건강신념변수는 심각성, 이득, 장애로 나타났고, 취약성은 상관 관계가 없는 것으로 나타났다. 각 신념 요인들과 건강행태 간의 상관되는 순서는 이득(r =.455), 심각성 (r=.38), 장애(r=-.244) 순으로 나타나 고지혈증에 대한 이득 인식이 건강행태 요인1과 가장 관련성이 높은 것으로 파악되었다. 그러나, 건강행태 요인2는 건강신념변수와 관련성이 없는 것으로 나타났다. 셋째, 행동계기에 따른 건강행태의 관계를 살펴보면, 교육을 받았을 때 건강행태 요인1과 요인2에 모두 유의한 차이를 보이는 것으로 나타나, 교육이 고지혈증 환자의 건강행태에 중요한 영향을 미치는 것을 보여 주었다. 넷째, 다중회귀분석 결과 고지혈증 건강행태 요인1에 영향을 미치는 요인 중 유의한 요인으로 인지된 심각성 및 이점 신념요인, 교육여부, 보건소 교육정도 이었다. 건강행태 요인2에서는 성별, 연령, 교육여부가 유의한 영향을 미치는 요인으로 나타났다. 이상의 결과를 종합하면 건강신념모형이 고지혈증 건강행태를 예측하는데 적합한 모형이라고 판단 할 수 있으며, 건강행태 요인 특성에 따라 건강신념변수 중 고지혈증 예방에 대한 이득을 높이 인식할 수 있도록 프로그램과 교육목표를 설정하면 보다 효과적인 교육이 될 것이라 생각된다.

• Korean Journal of Clinical Pharmacy
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• v.17 no.1
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• pp.13-18
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• 2007

The purpose of the present study was to investigate the effect of cimetidine on theophylline pharmacokinetics in Korean healthy normal subjects. Eight subjects were enrolled and open label, two period cross-over study was conducted without significant drug related adverse reactions. Cimetidine seemed that significantly inhibited the metabolism of theophylline, oral clearance decreased significantly when cimetidine was coadministered. Coadministered cimetidine increased $AUC_t$ and $C_{max}$ of theophylline. All subjects were genotyped using PCR-RFLP methods to evaluate the differences in metabolic capacity in accordance with CYP1A2 genotypes, but no mutant genotype was found. This suggests that metabolic capacities were not significantly affected by CYP1A2 genotypes among subjects. In conclusion, disposition of theophylline was significantly affected by coadministered cimetidine. Further evaluation with well-designed drug interaction study in accordance with various genotype of CYP1A2 is needed.

• Journal of Digital Convergence
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• v.16 no.2
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• pp.451-459
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• 2018

The aim of this study is to compare the differences in health promotion behaviors by the use of complementary alternative therapy(CAT) in elderly women with osteoarthritis. A total of 621 elderly women with osteoarthritis from public health centers and their branches at a city of C state were enrolled. This study analyzed the frequency and percentage of complementary alternative therapy utilization; a Chi-square test was used for utilization analysis according to subjects' general characteristics and disease features. Degree of health promotion behaviors according to CAT utilization was analyzed by a t-test and ANOVA. The study found that the CAT utilization rate for the total of 621 people was 61.7 %. For health promotion behaviors according to CAT utilization, statistically significant differences were found in exercise (p<0.001), health responsibility (p<0.001) and self-realization (p=0.016) from the domains. This study demonstrated the differences of health promotion behaviors based on CAT utilization. Due to the results of this study it is notable to mention that counseling, instruction for CAT utilization, and strategy development for health promotion are necessary for elderly women with osteoarthritis.

• Journal of Nutrition and Health
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• v.41 no.1
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• pp.54-64
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• 2008

We examined the effect of dietary behavior improvement on diet quality, body composition and blood lipid profiles in 68 middle-aged women. Dietary behavior intervention was consisted of counselling in the problem areas of portion control, food selection for low carbohydrate and high fiber food items, and education on the improvement of micronutrient intakes and diet quality. The subjects were divided into two groups; Improved or Not-Improved Group according to the level of changes in dietary behavior scores. After 6 months, body weight, BMI, waist-hip ratio, and visceral fat area were significantly decreased in the Improved Group compared to the Not-Improved Group. Calorie-adjusted protein, fiber, calcium, iron and vitamin C intakes were significantly increased in the Improved Group. The index of nutritional quality (INQ) and mean adequacy ratio (MAR) were increased only in the Improved Group. We observed a significantly increase in HDL-cholesterol and a decrease in total cholesterol, triglyceride and LDL-cholesterol, and an improvement of atherogenic index in the Improved Group. These results showed that dietary behavior intervention improved dietary behavior scores, and those whose dietary behavior score improved showed more improvement in diet quality, body composition, and serum profiles than those whose dietary behavior score did not improve.

• Journal of Life Science
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• v.21 no.3
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• pp.424-434
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• 2011

The purpose of this study was to examine the effects of a physical activity program on body composition, depression and risk factors of dementia in elderly women. Subjects were 40 women aged 65~75 years, classified into two groups (experiment group 20, control group 20). The factors measured in this study were body composition (weight, percent body fat, body mass index, body fluid), depression (BDI score) and risk factors of dementia (K-MMSE, LDL-C, HDL-C, insulin, ${\beta}$-amyloid, DHEAs) at 12 and 24 weeks before and after the program. Subjects of experiment group participated in a 24 week physical activity program (45~60 min, 3~4 day per weeks). Data were analyzed by repeated ANOVA method of SPSS, with accepting levels for all significances above ${\alpha}$=0.05. The results of this study were as follows. In body composition, the experiment group showed significant differences in the weight, percent body fat and body mass index compared to the control group. In depression score, the experiment group showed no significant differences regarding BDI score level compared to the control group. In risk factors for dementia, the experiment group showed significant differences in levels of K-MMSE, LDL-C, HDL-C, insulin, ${\beta}$-amyloid, and DHEAs compared to the control group. This study showed that a 24 week physical activity program had positive effects on almost all of the factors evaluated in elderly women, and that elderly women who did not participate in the program experiences no such positive effects. Therefore, regular participation in a physical activity program could be advocated as one strategy to enhance body fat, depression, and risk factors of dementia and may result in improving risk for diseases of age in elderly women.

• Journal of agricultural medicine and community health
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• v.40 no.2
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• pp.62-71
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• 2015

Objectives: This study was performed to find the differences in physical activity according to general characteristics and factors related to physical activity between the elderly over 65 with hypertension living rural and urban areas. Methods: This study included 681 participants (221 rural, 460 urban) with hypertension from The Fifth Korea National Health and Nutrition Examination Survey (KNHANES V). The collected data were analyzed through an $x^2$-test to examine the differences in physical activity and multiple logistic regression to assess factors related to physical activity between the elderly over 65 with hypertension living rural and urban areas. Results: The significant statistical factors related with physical activities for the urban hypertension group were education level, activities of daily living, and quality of life. However, the related factors for rural residents were activities of daily living and limitation of activity. Conclusions: The study results indicated that the factors that affected the level of physical activity revealed difference in case hypertension between the urban and rural groups. An awareness of the importance of physical activity will have a positive influence on improving the physical function and quality of life for elderly people with hypertension.

• Tuberculosis and Respiratory Diseases
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• v.45 no.1
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• pp.204-212
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• 1998

Bronchiolitis obliterans organizing pneumonia(BOOP) is a type of diffuse interstitial lung disease that has emerged in the past decade as an important cause of acute respiratory illness in adult. Clinically, the entity usually starts with a subacute influenza-like illness, followed by cough, progressive dyspnea, and weight loss. Organized inflammatory polypoid materials predominantly affecting distal bronchioles, alveolar ducts, and peribronchial alveolar spaces are a key pathologic findings. BOOP is characterized by a good response to glucocorticoid and an excellent prognosis. However, there is a subset of BOOP who presents with a fulminant course leading to death or chronic severe fibrosis with marked impairment of lung function. Recently, we have experienced a case of rapidly progressive BOOP, diagnosed by open lung biopsy and showed a reluctant response to corticosteroid.