• Journal of Korean Society of Environmental Engineers
• /
• v.30 no.9
• /
• pp.948-954
• /
• 2008

Membrane bioreactor(MBR) processes have been widely applied to wastewater treatment for last decades due to its excellent capability of solid-liquid separation. However, membrane fouling was considered as a limiting factor in wide application of the MBR process. Excess aeration into membrane surface is a common way to control membrane fouling in most MBR. However, the excessively supplied air is easily dissipated in the reactor, which results in consuming energy and thus, it should be modified for effective control of membrane fouling. In this study, cylindrical tube was introduced to MBR in order to use the supplied air effectively. Membrane fibers were immersed into the cylindrical tube. This makes the supplied air non-dissipated in the reactor so that membrane fouling could be controlled economically. Two different air supplying method was employed and compared each other; nozzle and porous diffuser which were located just beneath the membrane module. Transmembrane pressure(TMP) was monitored as a function of airflow rate, flux, and ratio of the tube area and cross-sectioned area of membrane fibers(A$_m$/A$_t$). Flow rate of air and liquid was regulated to obtain slug flow in the cylindrical tube. With the same flow of air supply, nozzle was more effective for controlling membrane fouling than porous diffuser. Accumulation of sludge was observed in the tube with the nozzle, if the air was not suppled sufficiently. Reduction of membrane fouling was dependent upon the ratio, A$_m$/A$_t$. For diffuser, membrane fouling was minimized when A$_m$/A$_t$ was 0.27, but 0.55 for nozzle.

• Journal of Korean Society of Environmental Engineers
• /
• v.28 no.1
• /
• pp.26-33
• /
• 2006

This study investigated the characteristics of the biofilm removal by free chlorine or monochloramine. The simulated drinking water distribution pipes on which biofilms had been formed were supplied with tap water containing 0.5, 1.0, 2.0 mg/L of free chlorine or monochloramine residuals. The biofilm removal was characterized by measurement of attached HPC and biomass on pipe surfaces. Chlorine was more effective in both inactivation of attached viable heterotrophic bacteria and removal of biofilm biomass compared to monochloramine. Biofilm matrix was not much eliminated from the surfaces by monochloramine disinfection. Free chlorine residual of 2.0 mg/L was found to be effective in biomass removal. However, biofilm level as low as $10CFU/cm^2$ of attached HPC and $5{\mu}g/cm^2$ of biomass still remained on the surfaces at 2.0 mg/L of chlorine residual. The measurement of biomass appeared to be a useful means in evaluating the characteristics of biofilm removal.

• Proceedings of the Korean Society of Applied Pharmacology
• /
• 1994.11a
• /
• pp.81-90
• /
• 1994

리포좀은 1960년대 초 Bangham등에 의해 혈액응고시 인지질의 영향에 관한 연구 중 우연히 발견하게 되었다. 즉 인지질이 물에 분산되어 2 분자막 (Bilayer)을 형성함을 알았고, 이때 생긴 폐쇄소포체를 리포좀이라 하였다. 이러한 리포좀은 원형질 막이나 세포내의 소기관의 막과 유사한 구조를 갖고 있기 때문에 이것을 이용하여 생화학자나 생물리학자들은 생체막의 모델시스템으로 이용하여 생체막의 기능 연구에 널리 이용하여 왔다. 1970년 초반부터 리포좀을 이용한 약물의 생체내 공급(Drug Delivery System, DDS)에 대하여 많은 연구가 이루어져 왔고, 지금까지도 의약품외 전달매체로 이용할려고 많은 시도를 하고 있는 실정이다. 최근에는 리포좀을 이용하여 항원을 전달하는 면역보조제(Adjuvant System)로 이용하려는 시도를 하고 있다. 현재까지 리포좀을 이용한 상품들은 화장품과 임상용 진단시 약, DNA transfection system (Lipopectin)으로 활용되고 있다.

• Proceedings of the Korea Water Resources Association Conference
• /
• 2023.05a
• /
• pp.288-288
• /
• 2023

도로, 철도 등의 횡단통로, 오폐수관로, 지하배수관 등 연약지반에서 상재하중과 부등침하에 의한 파괴 위험을 줄이기 위해 구조적인 안전성과 내구성이 개선된 다양한 관로들이 활용되고 있다. 관은 매설특성에 따라 콘크리트관, 도관, 합성수지관, 덕타일 주철관, 파형강관, 유리섬유 강화 플라스틱과 폴리에스테르수지 콘크리트관 등의 종류로 구분된다(환경부, 2017). 수리설계 시 이러한 관의 단면 규모 결정 및 흐름 특성을 파악하기 위해 관수로 유량측정에 이용되는 Manning의 경험식을 이용하고 있으며, 관로의 주요 재질에 따른 다양한 조도계수가 제시되어 있다. 새로운 재질을 이용하여 제작된 관은 수리실험을 통해 조도계수를 결정하는 것이 바람직하지만, 조도계수 실험은 대규모의 실험시설과 유량공급이 요구되기 때문에 여러 한계가 있다. PE관의 경우, 미국의 ASTM 표준에 의해 저밀도 폴리에틸렌(LDPE), 선형 저밀도 폴리에틸렌(LLDPE), 고밀도 폴리에틸렌(HDPE) 등으로 분류되는데 본 연구에서는 HDPE 재질의 서로 직경이 다른 다중벽관 PE관을 대상으로 조도계수를 결정하기 위한 현장 실규모 수리실험을 수행하였다. 본 실험에서는 식생, 수로의 불규칙성, 수로노선, 침전과 세굴, 장애물, 계절적 변화, 부유물질과 소류사는 무시되며 표면조도, 관의 크기와 형상, 수위와 유량이 조도계수에 영향을 미치는 주요 인자라고 할 수 있다. 수리실험은 실물모형(Prototype)으로 한국농어촌공사 농어촌연구원의 대형수리모형실험장에서 수행되었으며. 길이 24 m, 직경 150 mm의 PE 관은 고정식 개수로, 직경 800 mm의 관은 대형유사순환수로에 각각 설치되었다. 관로의 전면에 차폐막을 설치하여 상류부 수위를 안정시킨 상태에서 실험을 수행하였고, 차폐막으로부터 하류방향으로 약 7 m(측정기준지점), 11 m, 13 m, 15 m, 17 m 떨어진 곳에서 각각 수위와 유속을 측정하였다. 실험 결과, φ150관은 직경대비 수심이 클수록 조도계수가 감소하는 경향이 나타났고, φ800관은 직경대비 수심의 변화에 따른 조도계수의 경향이 크게 드러나지 않았다. 결론적으로 PE관의 조도계수는 수심별로 변화하는 것으로 나타났으며, 특정 수심을 지나면 조도계수가 다시 감소할 것으로 판단된다.

• Membrane Journal
• /
• v.14 no.1
• /
• pp.75-84
• /
• 2004

In this study, we present a noble study far membrane transport models using chlorine resistance of polyamide RO membranes. Membrane transport mechanism is investigated by the comparison of membrane permeation performance under the continuous and Intermittent operation modes with mixed feed solution containing NaOCl and NaCl. Analysis of permeation performance indicates that solution-diffusion model and preferential adsorption-capillary flow model are relatively efficient according to operation mode. Under the continuous flow state, mass transfer depends on preferential adsorption-capillary flow model rather than solution-diffusion model. On the other hand, it prefers solution-diffusion model to preferential adsorption-capillary flow model under the stationary state. SEM images of NaOCl treated membrane surfaces strongly support these conclusions. These surface images reveal that NaOCl treated membrane in continuous operation mode exhibits ridge and valley structure in some fraction of the surface area, whereas that in intermittent operation mode shows surface degradation entirely.

• Journal of Chest Surgery
• /
• v.35 no.9
• /
• pp.664-667
• /
• 2002

Extracorporeal membrane oxygenation(ECMO) provides stable oxygenation to prevent elevation of pulmonary vascular resistance and bypasses a significant part of cardiac output to the pulmonary vascular bed to reduce pulmonary perfusion pressure. In addition, ECMO prevents right heart failure and low cardiac output by means of ventricular assist and reduction in volume load to right ventricle. As a result, ECMO can be used for the treatment of pulmonary hypertensive crisis after surgery for congenital heart disease, especially when it is refractory to conventional measures. We report a case of postoperative pulmonary hypertensive crisis, developed in a 37-year-old male with patent ductus arteriosus with secondary pulmonary hypertension, which was successfully managed including ECMO.

• Membrane Journal
• /
• v.2 no.1
• /
• pp.21-32
• /
• 1992

Hydrogen-permselective silica membranes were synthesized within tim walls of porous Vycor tubes by chemical vapor depostion of $SiO_2$. Film deposition was carried out using $SiCl_4$ hydrolysis either in the oppm shag reactants or in the one-sided geometry. At temperatures above $600^{\circ}C$ the permeation rate of hydrogen thorough the silica films varied between 0.01 and $025cm^3(STP)/cm^2-min-atm$ depending on the reaction geometry and the $H_2 : N_2$ permeation ratio was about 1000. Permeation rates of both $H_2$ and $N_2$ increased with increasing temperature. The silica membranes produced by one-sided deposition have higher hydrogen permmeation rates than those produced by the opposing reactants geometry although the membranes formed in an opposing reactants geometry were relatively stable during the heat treatment or after exposure to ambient air. These membranes can be applied to high temperature gas separations or membrane reactors once the film deposition process is optimized to get high permeability as well as good stability.

• Proceedings of the Korean Society of Propulsion Engineers Conference
• /
• 2012.05a
• /
• pp.416-423
• /
• 2012

Liquid acquisition device in the liquid propellant supply system is required to protect entrance of gas bubble into the propulsion system. The device exploits the capillary effect of micro-sized poles in a screen and supplies pure liquid-phase propellant to the propulsion system. The bubble point is the most important performance parameter in the design of a liquid acquisition device. In this paper, performance parameters affecting the bubble point are identified through literature survey, in order to develop the experimental setup for the bubble point measurement.

• Applied Microscopy
• /
• v.31 no.3
• /
• pp.287-305
• /
• 2001

To investigate a role of cartilage canals in osteogenesis and growth of the vertebrae, in human fetuses ranging from 50 mm to 260 mm crown rump length were studied by electron microscopy. The initial appearance of cartilage canals of the vertebral body was observed at 60 mm fetus. In 80 mm fetus, primary ossification center in the vertebral body was first noted. The vertebral body showed calcified chondrocytes surrounded by a tone of hypertrophied chondrocytes and deep canals which terminated in calcified matrix. Most hypertrophied chondrocytes in the centrum showed in various stage of degeneration in disorderly arrangement. At the blind end of deep canal, osteogenic cells, osteoblasts and chondroclasts were observed. Resorption of unmineralized cartilage septa was undertaken by perivascular cells within cartilage canals. The ruffled border of the chondroclast was restricted to resorption site of calcified cartilagenous matrix. The periosteal bone formation was followed by the appearance of primary center of the centrum at 120 mm fetus. The osteoblasts of the perichondrium started to lay down a thin membranous bony lamella on the outer surface of the osseous trabeculae of the centrum. The processes of bone formation in the vertebral bodies were found to possess morphological similarities to that occurring at secondary center of the epiphysis of a long bone. These results indicate that the connective tissue cells within the cartilage canals proliferate and differentiate into osteoblasts at the site of endochondral ossification of the vertebrae.

• Applied Microscopy
• /
• v.32 no.2
• /
• pp.91-105
• /
• 2002

Urea transport in the kidney is mediated by a family of transporter proteins that includes renal urea transporters (UT-A) and erythrocyte urea transporters (UT-B). The cDNA of five isoforms of rat UT-A, UTA1, UT-A2, UT-A3, UT-A4, and UT-A5 have been cloned. The purpose of this study was to examine the expression of UT-A (L194), which marked UT-A1, UT-A2 and UT-A4. Male Sprague-Dawley rats, weighing approximately 200 g, were divided into three group: control rats had free access to water, dehydrated rats were deprived of water for 3 d, and water loaded rats had free access to 3% sucrose water for 3 d before being killed. The kidneys were preserved by in vivo perfusion through the abdominal aorta with the 2% paraformaldehyde-lysine- periodate (PLP) or 8% paraformaldehyde solution for 10 min. The sections were processed for immunohistochemical studies using pre-embedding immunoperoxidase method and immunogold method. In the normal rat kidney, UT-A1 was expressed intensely in the cytoplasm of the inner medullary collecting duct (IMCD) cell and UT-A2 was expressed on the plasma membrane of the terminal portion of the shortloop descending thin limb (DTL) cells (type I epithelium) and of the long-loop DTL cells (type II epithelium) in the initial part of the inner medulla. Immunoreactivity for UT-A1 in the IMCD cells, was decreased in dehydrated animals whereas strongly increased in water loaded animals compared with control animals. In the short-loop DTL, immunoreactivity for UT-A2 was increased in intensity in both dehydrated and water loaded groups. However, in the long-loop DTL of the outer part of the inner medulla, immunoreactivity for UT-A2 was markedly increase in intensity in dehydrated group, but not in water loaded group. In conclusion, in the rat kidney, UT-A1 is located in the cytoplasm of IMCD cells, whereas UT-A2 is located in the plasma membrane of both the short-and long-loop DTL cells. Immunohistochemistry studies revealed that UT-A1 and UT-A2 may have a different role in urea transport and are regulated by different mechanisms.