• Journal of Life Science
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• v.32 no.6
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• pp.447-454
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• 2022

In this study, we confirmed the effect of HK shiitake mushroom mycelium (HKSMM) on immune enhancement in Balb/c mice. Experimental animals were divided into five groups: negative control (NC), positive control (PC; 1,000 mg/100 g; AHCC), T1 (500 mg/100 g; HKSMM), T2 (1,000 mg/100 g; HKSMM), and T3 (2,000 mg/100 g; HKSMM), and dissection was performed at four and six weeks. COX-2 and iNOS concentrations were significantly lower in the six-week experimental group than in the control group, and the NO results were also similar. Results of the confirmation of the factors related to the NF-κB (p-p65 and p-IκBα) and MAPK (pERK, pJNK, and p38) signaling pathways revealed that the HKSMM-fed experimental group significantly decreased compared with the control group. A comparative analysis of the number and size of white pulp in the spleen tissue showed that those of the experimental group were significantly higher than those of the control group in a concentration-dependent manner. These results suggest that HKSMM has both immune-enhancing and anti-inflammatory effects in Balb/c mice, indicating that it can be used as a health functional food ingredient.

• Journal of Digital Convergence
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• v.10 no.9
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• pp.333-338
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• 2012

This paper is related to a skinny smudge blending method using the arbitrary-shaped master adhered closely to the contour shape. The smudge tool is the popular graphic tool embedded in Adobe Photoshop CS6. The smudge tool is used to smear paint on your canvas. The effect is much like finger painting. We can use the smudge tool by selecting its icon on the toolbox of Adobe Photoshop CS6 and dragging in the direction you want to smudge while holding the mouse button down on the image. As the smudge tool blends all the pixels within a radius of the master to generate the result image, its disadvantages are to smudge even the pixels in the undesired region. In this paper to reduce the disadvantage, the skinny smudge blending method using arbitrary-shaped master is proposed. The proposed blending method has the advantage of applying the smudge effect to the desired regions regardless of the background as the arbitrary-shaped master adhered closely to the contour shape is extracted by color image segmentation.

• Journal of The Korean Association of Information Education
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• v.5 no.3
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• pp.374-379
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• 2001

Recently, R & D about Network Monitoring System is needed to be effective network management and to improve computer education. In this work, we propose a real time network monitoring system named NetCop to improve network management and effective use. This system is designed to show any screen to one or more students in interactive learning environment. The system also provides useful functions such as monitoring students' PCs and chat. In additions, our NetCop can provide more effective learning process to students. Finally, we expect that our system can achieve high network performance and provide high educational quality to managers.

• Journal of the East Asian Society of Dietary Life
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• v.18 no.2
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• pp.198-206
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• 2008

갯쑥(Artemisia fukudo Makino, 일명 바다쑥)은 바닷가 염전 주변 습지에서 자라는 염생식물로 어린 갯쑥은 나물로 먹어왔으며, 민간에서 간에 좋다고 알려져 있다. 본 연구에서는 염생식물의 기능 성분을 탐색하는 연구의 일환으로 마우스유래 대식세포주인 RAW264.7세포를 이용하여 갯쑥의 nitric oxide(NO) 생성 억제 작용을 알아보고자 하였다. 갯쑥은 methanol 추출과 열수 추출한 후 농축하여 실험하였고, methanol 추출물은 다시 hexane, chloroform, ethylacetate, butanol, water로 순차 용매 분획하여 농축하여, 각각의 추출물을 RAW 264.7 세포에 농도별 분획별로 처리한 후 LPS와 interferon-${\gamma}$로 자극한 RAW 264.7 세 포주의 NO 생성을 측정하여 NO 생성 저해율을 구하였다. 갯쑥 methanol 추출물의 높은 NO 생성 저해율과 iNOS 활성 저해율을 나타내었으며(IR=90.7%과 IR=81.6%), 각각의 추출물중 분획물이 100${\mu}g/mL$ 농도에서 hexane 분획물이 가장 높은 NO 생성 저해 효과(IR=92.1%)와 iNOS 활성 억제 효과(IR=85.0%)를 나타내었다. 갯쑥의 methanol 추출물, hexane과 chloroform 분획물에서 높은 NO 생성 저해 효과를 나타내어 새로운 암 예방인자 물질로 기대되며, 따라서 본 연구 결과는 암 예방인자 분리를 위한 기초 자료가 될 것이며, 나아가 성분 분리 연구와 동물 실험을 통한 기전 연구가 수행되어야 할 것이다.

• 한국HCI학회:학술대회논문집
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• 2008.02a
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• pp.579-583
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• 2008

Web pages with complex layout and small font size do not display well on large screen display such as TV because it has limited capabilities: long distance view, passive user attitude, limited input device like a legacy remote controller. We have designed and implemented new semantic zoom browsing facilities to support effective navigation on Internet-connected digital television with limited capabilities. Our browser performs partitioning of an HTML document content into semantic blocks. Semantic blocks present summarized information with more readable style and modified layout for optimal reading and browsing. Individual blocks can be selected by the user and zoomed in more detail information by the user. The scrolling on large display device needs more user interaction. Our browser modifies the layout of an HTML document with removing horizontal scrolling and minimizing vertical scrolling. This method allows users to easily view the web page by converting into optimal reading style and layout and to easily seek the information just with zooming.

• 한국HCI학회:학술대회논문집
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• 2008.02a
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• pp.553-558
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• 2008

In this paper, we develop a vibration system which can generate diverse vibration effects in realtime by analyzing signals from the sound output of PC. This system is able to detect the occurrences of particular sounds in order to generate corresponding pre-programmed vibration patterns. It contributes to the improvement of the reality and the immersiveness of games and virtual reality applications. In addition, its advantage is to easily add vibration features to applications which were originally developed without consideration for vibration. Our system consists of an external DSP board for signal processing and a vibration pad which can be put on wrists. It is superior to other sound-driven vibration devices because its DSP board can detect more diverse sounds, has higher performance and does not interfere with PC. Also the wrist-wearable vibration pad is able to generate more realistic vibration than other mouse or joystick type devices.

• Journal of Physiology & Pathology in Korean Medicine
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• v.18 no.4
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• pp.995-1000
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• 2004

This study was purposed to investigate the effect of Gamgung-tang(GGT) on immune responses induced by glucocorticoid in mice. GGT solution was treated by intraperitoneal injection for 7 days after glucocorticoid treatment(80㎎/㎏). And then B and T cell proliferation and cytolytic activity of natural killer(NK) cells were measured. There was 25% inhibition in B cell proliferation with treatment of glucocorticoid. However, B cell proliferation was not influenced by GGT treatment. T cell proliferation was also inhibited by 18.4% with treatment of glucocorticoid. On the other hand, T cell proliferation was increased dose-dependent manner in GGT treated group. Furthermore in purified T cell, the proliferation was furtherly increased than non-purified T cell. At concentration of 18㎎/mouse GGT, purified T cell proliferation was increase to above level of normal group. The cytotoxic activity of NK cell was decreased by 35.3% with treatment of glucocorticoid. In GGT treated group, the cytotoxic activity of NK cell was increased to the normal level. In purified NK cell, the cytolytic activity of NK cell was further increased than non-purifed NK cell. These results suggest that GGT may proliferate T cell that is suppressed by glucocorticoid, and activate NK cell activity.

• 한국HCI학회:학술대회논문집
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• 2009.02a
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• pp.111-115
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• 2009

This paper is related to a skinny smudge tool based on the image segmentation for a master shape. The smudge tool is the popular graphic tool embedded in Adobe Photoshop. The smudge tool is used to smear paint on your canvas. The effect is much like finger painting. You can use the smudge tool by clicking on the smudge icon and clicking on the canvas and while holding the mouse button down, dragging in the direction you want to smudge. A disadvantage of previous smudge tool is to also smear pixels in the undesired region according to generating the target image as blending all pixels in a diameter of the master. In this paper to reduce the disadvantage, the skinny smudge tool based on the image segmentation for a master shape is proposed. The proposed skinny smudge tool has the advantage of applying the smudge effect to the desired regions regardless of the background as the master shape adhered closely to the contour shape is extracted by color image segmentation.

• 한국HCI학회:학술대회논문집
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• 2009.02a
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• pp.512-515
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• 2009

In this paper, we propose layout based multimodal contents authoring tool for Digilog Book. In authoring step, users create a virtual area using mouse or pen-type device and select property of the area repetitively. After finishing authoring step, system recognizes printed page number and generate page layout including areas and property information. Page layout is represented as a scene graph and stored as XML format. Digilog Book viewer loads stored page layout and analyze properties then augment virtual contents or execute functions based on area. Users can author visual and auditory contents easily by using hybrid interface. In AR environment, system provides area templates in order to help creating area. In addition, proposed authoring tool separates page recognition module from page tracking module. So, it is possible to author many pages using only single marker. As a result of experiment, we showed proposed authoring tool has reasonable performance time in AR environment. We expect that proposed authoring tool would be applicable to many fields such as education and publication.

• Journal of the Korean Society for information Management
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• v.30 no.1
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• pp.193-219
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• 2013

Public institutions or libraries urgently prepare comprehensive measures to improve web accessibility of their websites as booting web dependability and web utilization of disabled people. The purpose of this study is to propose the design guidelines for improving web accessibility of disabled people. The study, first, analyzed various web accessibility requirements based on web standards, web accessibility guidelines, and the related researches and proposed a web accessibility checklist with 42 requirement. Next, the study evaluated 15 websites of public institutions such as government departments, association of disabled people, and public libraries using the checklist. Finally, the study revealed non-adherence requirements and suggested website design guidelines in terms of contents configuration, sound, colour, keyboard handling, mouse handling, access, image processing, text processing, and code processing.