• Title/Summary/Keyword: 리신

Search Result 131, Processing Time 0.023 seconds

Material Characteristics, Provenance Interpretation and Deterioration Diagnosis of Shilla Stone Monuments in Jungseongri and Naengsuri, Pohang (포항 중성리신라비와 영일 냉수리신라비의 재질특성과 산지해석 및 훼손도 진단)

  • Lee, Myeong Seong;Han, Min Su;Kim, Jae Hwan;Kim, Sa Dug
    • Korean Journal of Heritage: History & Science
    • /
    • v.43 no.3
    • /
    • pp.122-143
    • /
    • 2010
  • The Shilla Stone Monument in Jungseongri was found during the road-construction in Pohang. It has approximately two hundreds of letters inscribed on the surface of one side, and it is estimated to be older than Shilla Stone Monument in Naengsuri which had been known for the oldest stele in Shilla Period. This monument is made of fine to medium-grained biotite granite, while the Shilla Stone Monument in Naengsuri is made of fine-grained granodioritic porphyry bearing feldspar and amphibole phenocrysts. Both rock types of the monuments are interpreted to be cognate with biotite granite in Shinkwangmyeon, and with granodioritic porphyry in Gigyemyeon. They are characterized by xenolith and miarolitic cavity. Damage aspects in both monuments are discoloring, cracking and breaking. These damages do not cause structural instability of the monuments, but attenuate aesthetic value. Black and brown discoloring contaminants on the surface of the Jungseongri Monument contain a high amount of manganese and iron. As a result of ultrasonic test, both monuments were evaluated to be medium-weathered (MW), although the velocity of the Shilla Monument in Jungseongri was slightly lower than the Shilla Monument in Naengsuri. This is because the Monument in Juengseongri had been exposed to outdoor environment for long time until the discovery. It is necessary for Shilla Monuments to be protected by appropriately environmental control and management.

The Effects of Either Chrysin or Moderate Exercise on Inflammasome and Thermogenic Markers in High Fat Fed Mice (고지방식이 동물의 간 조직에서 크리신 투여 또는 중강도 운동이 Inflammasome과 열 발생 유전자발현에 미치는 효과)

  • Lee, Young-Ran;Park, Hee-Geun;Lee, Wang-Lok
    • Journal of Life Science
    • /
    • v.29 no.5
    • /
    • pp.607-613
    • /
    • 2019
  • The purpose of this study was to investigate the effects of either chrysin or exercise on the inflammasome and thermogenic markers in the livers of high-fat fed mice. C57BL/6 mice were randomly assigned to four groups: normal diet control (NC; n=5), high-fat diet control (HC; n=5), high-fat diet with chrysin (Hch; n=5), and high-fat diet with moderate exercise (HME; n=5). The mice were fed a high-fat diet (60% of calories from fat) or normal diet (18% of calories from fat). Chrysin was supplemented orally as 50mg/kg/day dissolved in a 0.1ml solution of dimethyl sulfoxide. The exercised mice ran on a treadmill at 12-20 m/min for 30-60 min/day, 5 times/week, for 16 weeks. After the intervention, the epididymal fat and liver weights were significantly decreased in the HME group compared with HC and Hch groups. The adipocyte size was effectively decreased in the Hch and HME groups compared with the HC group. The inflammasome markers NLRP3, $IL-1{\beta}$, and caspase1 were significantly decreased in the Hch and HME groups compared with the HC group. The thermogenic markers $PGC-1{\alpha}$ and BMP7 were significantly lower in the HC than in the NC group. However, the HME group showed an increase in the thermogenic markers. In conclusion, chrysin and moderate exercise have positive effects on obese metabolic complications induced by high-fat diets by reducing inflammasome genes. However, chrysin supplementation had no effect on thermogenic gene expression. Moderate exercise would therefore seem to be more effective in controlling obesity-induced metabolic deregulation.

Expression of Human Lactoferricin in HC11 Cells (HC11 세포에서 인체 락토페리신의 발현)

  • Nam, Myoung-Soo
    • Korean Journal of Agricultural Science
    • /
    • v.28 no.2
    • /
    • pp.92-98
    • /
    • 2001
  • Lactofenicin is an antibacterial peptide fragment (about 5 kD) derived from lactoferrin (80 kD) that displays the various biological functions. The production of a human lactoferricin (Lactoferricin H) in mouse HC11 mammary epithelial cells was achieved by placing its cDNA under the control of the bovine ${\beta}$-casein gene. To express lactoferricin H in this cell culture system, constructed a hybride-splice signal consisting of bovine ${\beta}$-casein intron I and rabbit ${\beta}$-globin intron II, and a DNA fragment spanning intron 8 of the bovine ${\beta}$-casein gene. Expression of lactofenicin H from this expression vector was identified by RT-PCR, northern and dot blot analysis. RT-PCR using total RNA of HC11 cells transfected with pBL1-cin expression vector yielded a product identified as having a size of the 150bp. Northern blot analysis was identified about 2.3 kb. In dot blot analysis, recombinant lactofenicin H was recognized with anti-human lactofrrnin polyclonal antibody.

  • PDF

Effects of Aerobic Exercise and Chrysin Supplementation on Macrophage Infiltration and Lipolysis Genes of High-Fat Diet Mice (고지방식이 동물모델에서 크리신 섭취와 유산소 운동이 대식세포 침윤과 지방분해 유전자들에 미치는 영향)

  • Choi, Do-Yourl;Lee, Young-Ran
    • Journal of Digital Convergence
    • /
    • v.17 no.5
    • /
    • pp.399-405
    • /
    • 2019
  • This study was investigated the effect of aerobic exercise and chrysin supplementation on macrophage infiltration and lipolysis in high-fat diet mice. To accomplish the purpose of this study, C57BL/6 mice were fed high fat diet(60% fat diet) during experimental period. The animals were divided into 4 groups; NC (normal diet control, n=5), HC (high fat diet control, n=5), Hch(high fat diet with chrysin, n=5), and HME (high fat diet with aerobic exercise training, n=5). Exercise training was performed for 16 weeks on a treadmill running. As a result, macrophage marker, F480 and CD11c were significantly decreased in HME comparison with HD and Hch. Also, M2 macrophage marker CD11c, and lipolysis marker PRDM were significantly increased in HME compared with HC and Hch These findings suggest that regular aerobic exercise has beneficial effects to inhibit macrophage infiltration in high fat diet mice.

Effects of 12-Weeks Dance Sports Exercise on Body Composition, Irisin, Adiponectin and Blood Lipids in Obesity Elderly Women (12주간의 댄스스포츠운동이 비만노인여성의 신체조성, 아이리신, 아디포넥틴 및 혈중지질에 미치는 영향)

  • Lee, jin-wook;Zhang, seok-am;Kim, chan-yang
    • 한국체육학회지인문사회과학편
    • /
    • v.58 no.1
    • /
    • pp.271-284
    • /
    • 2019
  • The purpose of this study was to analyze effects of 12 weeks dance sports on body composition, irisin, adiponectin and blood lipids in obesity elderly women. The subjects were 26 obesity elderly women who do not have medically problems. The subjects randomly assigned to two groups; dance sports exercise(n=13), control(n=13). The subjects in dance sports group were participated for 60 minutes/day with two times/wk for 12 weeks, whereas subjects in control group were asked to maintain normal lifestyle during the same intervention period. The results of the present study showed that the blood irisin was significantly increased in the exercise group. The blood adiponectin level tended to increase in the exercise gorup. The blood lipids, TG and LCL-C were significantly decreased in the exercise group. The TC was slightly decreased, and the HDL-C was slightly increased. In conclusion, low irisin and adiponectin level in obese people have a positive effect on obese elderly women after dance sports. Therefore, exercise is thought to be good for the care of elderly obesity.