• Journal of the Korean Society for Advanced Composite Structures
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• v.1 no.2
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• pp.1-13
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• 2010

Delamination reduces an elastic buckling load of the laminated composite structures and lead to global structural failure at loads below the design level. Therefore, the problem of the delamination buckling of laminated composite structures has generated significant research interest and has been the subject of many theoretical and experimental investigations. However, questions still remain regarding a complete understanding and details of the phenomena involved. In this paper an efficient finite element model is presented for analyzing the elastic buckling behavior of laminated composite plates with square embedded delamination using a solid element based on a three-dimensional theory. The solid finite element, named by EAS-SOLID8, based on an enhanced assumed strain method is developed. The study for elastic buckling behavior of laminated composite plates with embedded square delaminations are focused on various parameters, such as support condition and width-to-thickness ratio. Both graphs and buckling modes in this paper are good guide for design of the laminated composite plates with embedded square delamination.

• Journal of Pharmaceutical Investigation
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• v.31 no.3
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• pp.191-196
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• 2001

Biodegradable polymeric microspheres were studied for their usefulness as carriers for the delivery of vaccine antigens. However, protein antigen could be denatured during microencapsulation processes due to the exposure to the organic phase and stress condition of cavitation and shear force. Therefore this study was carried out to re-evaluate the degree of protein denaturation during microencapsulation with poly(lactide-co-glycolide) (PLGA) copolymer. PLGA microspheres containing ovalbumin (OVA), prepared by W/O/W multiple emulsification method, were suspended in pH 7.4 PBS and incubated with shaking at $37.5^{\circ}C$. Drug released medium was collected periodically and analyzed for protein contents by micro-BCA protein assay. In order to evaluate the protein integrity, release medium was subjected to the analyses of SDS-PAGE and size exclusion chromatography (SEC). And enzyme-linked immunosorbent assay (ELISA) was introduced to measure the immunoreactivity of entrapped OVA and to get an insight into the three-dimensional structure of epitope. The structures of entrapped protein were not affected significantly by the results of SDS-PAGE and SEC. However, immunoreactivity of released antigen was varied, revealing the possibility of protein denaturation in some microspheres when it was evaluate by ELISA method. Therefore, in order to express the degree of protein denaturation, antigenicity ratio (AR) was obtained as follows: amount of immunoreactivity of OVA/total amount of OVA released ${\times}100(%)$. ELISA method was an efficient tool to detect a protein denaturation during microencapsulation and the comparison of AR values resulted in more accurate evaluation for immunoreactivity of entrapped protein.

• Journal of Pharmaceutical Investigation
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• v.32 no.3
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• pp.199-207
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• 2002

In order to develop a sustained release formulation of bovine somatotropin (BST), which has been used to increase the body weight of oxen or the milk production of dairy cows, poly(D,L-lactide-co-glyceride)(PLGA) microspheres were made by W/O/W multiple emulsification method and solvent extraction method. Physical properties including particle size, drug entrapment, drug release, protein denaturation, and in vivo body weight increase in rats were characterized. The size of the microspheres was increased as the molecular weight of PLGA increased. When Span 65 and stearic acid during preparation were added, the size was decreased but the amount of surface protein was increased, resulting in a high loading efficiency, with fast release of BST from the microspheres. Aggregation or fragmentation of BST by SDS-PAGE during microsphere preparation and drug release study was not observed. Body weight of Sprague-Dawley's male rats was significantly increased after subcutaneous administrations of BST-loaded PLGA microspheres. There was a good correlation between in vivo weight gain and in vitro release rate of microspheres. PLGA microspheres with a high surface protein ratio could be a good candidate for the sustained delivery of BST.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.21 no.5
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• pp.426-432
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• 2020

Music with the development of the media since the 20th century marks a change into an era where the live performance and music of the masses, which were hard to imagine in previous times, are shared. Based on this cultural trend, teenage music, which has been completely alienated from existing culture, is in line with the birth of Rock 'n' Roll, an event that has entered the mainstream, and the emergence of the guitar, especially the solid body electric guitar. The Fender Stratocaster, which is referred to as the epitome of this electric guitar, has joined the history of popular music for rock 'n' roll. To this day, the immense influence, which still encompasses many followers and generations, has served as a bridge that continues to be reproduced, even in the historical trend of popular music and the status of electric guitars. In addition, even in the rapid development of popular music and media, we will always be able to give true meaning and value to the vitality with the times. This paper examines the features and marks of these Fender Stratocasters.

• Journal of the Korean Society of Propulsion Engineers
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• v.8 no.2
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• pp.102-114
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• 2004

The present work has been developed the interpretation processor including the behavior of material failure and the separation phenomena under transient dynamic loading (the operation of explosive bolt) using AUTODYN V4.3, SoildWork 2003 and TrueGrid V2.1 programs. It has been demonstrated that the interpretation in ridge-cut explosive bolt under dynamic loading condition should be necessary to the appropriate failure model and the basic stress of bolt failure is the principal stress. The use of this interpretation processor developing the present work could be extensively helped to design the shape and the amount of explosives in the explosive bolt having a complex geometry. It is also proved that the interpretation processor approach is an accurate and effective analysis technique to evaluate the separation mechanism in explosive bolts.

• Journal of Astronomy and Space Sciences
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• v.25 no.4
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• pp.395-404
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• 2008

We explore the linkage between the long term variability of the Sun and earth's climate change by analysing periodicities of time series of solar proxies and global temperature anomalies. We apply the power spectral estimation method named as the periodgram to solar proxies and global temperature anomalies. We also decompose global temperature anomalies and reconstructed total solar irradiance into each local variability components by applying the EMD (Empirical Mode Decomposition) and MODWT MRA (Maximal Overlap Discrete Wavelet Multi Resolution Analysis). Powers for solar proxies at low frequencies are lower than those of high frequencies. On the other hand, powers for temperature anomalies show the other way. We fail to decompose components which having lager than 40 year variabilities from EMD, but both residuals are well decomposed respectively. We determine solar induced components from the time series of temperature anomalies and obtain 39% solar contribution on the recent global warming. We discuss the climate system can be approximated with the second order differential equation since the climate sensitivity can only determine the output amplitude of the signal.

• Journal of Korea Technology Innovation Society
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• v.19 no.3
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• pp.572-603
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• 2016

This study examines how scientists understand standardization and standardization policy in the Korean national R&D context and analyze future policy direction of standardization policy. Interview with 15 scientists at universities and government-funded research institutes who have participated national R&D (particularly in the field of technology convergence) were conducted. The results show that considerations of standardization at the process of technology convergence is somewhat different from them at the process of general R&D. Also, considerations of standardization at the process of technology convergence is needed at the later time within the R&D time schedule because of low visibility and forecasting on the technology convergence outcome. It finds that "standardization by private sector" is the future policy direction in Korea. The government needs to be remained as "helper" for private sector to lead standardization in a globalized market

• Journal of the Korean Applied Science and Technology
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• v.24 no.2
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• pp.149-159
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• 2007

In order to prepare high-solid coatings, acrylic resins, HSCs [poly (EA/EMA/2-HEMA/CLA)] that contain 90% solid, were synthesized by copolymerization of ethyl acrylate (EA), ethyl methacrylate (EMA), 2-hydroxyethyl methacrylate (2-HEMA) and caprolactone acrylate (CLA). The high-solid coatings named as CHSCs (HSCs/HDI-trimer) were prepared by the curing reaction between the acrylic resins containing 90% solid contents and the isocyanates (HDI-trimer) curing agent room temperature. The curing behavior and various properties were examined on the film coated with the both high-solid coatings. The glass transition temperatures $(T_g)$ of CHSCs increased proportionally with increasing the predicted $T_g$ value by Fox equation, and had nothing to do with the solid contents. The prepared film showed good properties for $60^{\circ}$ specular gloss, impact resistance, cross-hatch adhesion and heat resistance, and bad properties for pencil hardness, drying time, and pot-life. Among the film properties, the heat resistance was very excellent and could be explained by the introduction of functional monomers of CLA.

• The Journal of the Korea Contents Association
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• v.16 no.5
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• pp.205-216
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• 2016

This study aimed to discover the most influential player in the network of Soccer game and how individual players contribute within the team with quantitative capabilities they possess. It also examined whether or not the network of relationship between players and the coach's tactics were in harmony. The results showed high level of correlation between the network between offenders and defenders according to tactics of the coach during the first half. It can be said that each players fulfilled their role and formed a network within them to lead the game and form a virtuous network structure. On the other hand, the overall network of the team was focused on a specific player during the second half. But the coach's appropriate use of substitutes and change in tactics stabilized the network balance between the players.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.17 no.7
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• pp.263-272
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• 2016

Modular product design has contributed to flexible product modification and development, production lead time reduction, and increasing product diversity. Modular product design aims to develop a product architecture that is composed of detachable modules. These modules are constructed by maximizing the similarity of components based on physical and functional interaction analysis among components. Accordingly, a systematic procedure for clustering the components, which is a main activity in modular product design, is proposed in this paper. The first phase in this procedure is to build a component-to-component correlation matrix by analyzing physical and functional interaction relations among the components. In the second phase, network flow modeling is applied to find clusters of components, maximizing their correlations. In the last phase, a network flow model formulated with linear programming is solved to find the clusters and to make them modular. Finally, the proposed procedure in this research and its application are illustrated with an example of modularization for a vacuum cleaner.