• Journal of Convergence for Information Technology
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• v.10 no.5
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• pp.143-149
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• 2020

The aim of this study was to examine the perceptions and attitudes of dental hygienists on the use of dental loupes. A questionnaire survey was conducted to 180 dental hygienists working at dental institutions and public health centers. 4.6% of all respondents answered that they use dental loupes currently, and 38.9% answered that they need to introduce dental loupes in the dental clinic. About half indicated that loupes were a benefit to improved vision(53%) and Improved clarity(44%). The most commonly reported disadvantages to loupes wear were limited depth of vision(39%) and overall dependency. It was confirmed that most dental hygienists did not use loupes, there was little interest in loupes. More research is needed on the effects of loupes in dental practice.

• Journal of Life Science
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• v.33 no.11
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• pp.859-867
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• 2023

Lupeol is a type of pentacyclic triterpene that has been reported to have therapeutic effects for treating many diseases; however, its effect on insulin resistance is unclear clear. This study examined the inhibitory effect of lupeol on the serine phosphorylation of insulin receptor substrate-1 in insulin resistance-induced 3T3-L1 adipocytes. 3T3-L1 cells were cultured and treated with tumor necrosis factor-α (TNF-α) for 24 hours to induce insulin resistance. Cells treated with different concentrations of lupeol (15 μM or 30 μM) or 100 nM of rosiglitazone were incubated. Then, lysed cells underwent western blotting. Lupeol exhibited a positive effect on the negative regulator of insulin signaling and inflammation-activated protein kinase caused by TNF-α in adipocytes. Lupeol inhibited the activation of protein tyrosine phosphatase-1B (PTP-1B)-a negative regulator of insulin signaling-and c-Jun N-terminal kinase (JNK); it was also an inhibitor of nuclear factor kappa-B kinase (IKK) and inflammation-activated protein kinases. In addition, Lupeol downregulated serine phosphorylation and upregulated tyrosine phosphorylation in insulin receptor substrate-1. Then, the downregulated phosphatidylinositol 3-kinase (PI3K)/protein kinase B (AKT) pathway was activated, the translocation of glucose transporter type 4 was stimulated to the cell membrane, and intracellular glucose uptake increased in the insulin resistance-induced 3T3-L1 adipocytes. Lupeol may improve TNF-α-induced insulin resistance by downregulating the serine phosphorylation of insulin receptor substrate 1 by inhibiting negative regulators of insulin signaling and inflammation-activated protein kinases in 3T3-L1 adipocytes.

• Proceedings of the Korea Information Processing Society Conference
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• 2022.11a
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• pp.113-115
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• 2022

치과 진료는 대부분 인간의 시각에 의존하여 진단과 진료가 이루어진다. 하지만 미세한 치아 손상의 경우 의사가 육안으로 확인하기 어려울 수 있으며, 의사의 실력 및 피로 누적에 의해 조기에 발견을 하지 못할 가능성이 높아진다. 만약 미세한 치아 손상을 조기에 발견하지 못할 경우 시간이 지남에 따라 손상 부위가 커지고, 이를 치료하기 위해 더 큰 비용과 고통이 따르기 때문에 치과에서의 조기 발견이 매우 중요하다. 한편, 인류는 디지털 헬스케어 기술을 개발하여 보다 정확한 진단을 할 수 있게 되었고, 의료 서비스를 효율적으로 제공할 수 있게 되었다. 이에 본 논문에서는 위의 문제를 해결하기 위해 디지털 헬스케어를 사용하여 빅데이터와 딥러닝을 활용한 지능형 전자 루페에 대해 탐구하였다.

• Resources Recycling
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• v.7 no.2
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• pp.39-45
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• 1998

We smelted thc pellets made by mixing the distilled carbon from wlISte Lires, LD converter dust and slag with reduction process in the revcrberatory furnace. Thc obtained results are as follows 1) The removal mte of zinc appears above 97% after T reducing the pellets at $1300^{\circ}C$ for Ihr and the zinc content in the residue are 0.1~D.2%. 2) Under the mixing condition of 500 g LD dust. 150-200 g LD slag and 30-50 g distilled carbon of waste lires the removal raho of zinc shows above 95%, while t the 50-60% Fe remains in the residue. 3) After smelting at $1350^{\circ}C$ for 3hrs, the recovery ratio of pig iron reduced from lhe p pellets containing 15-20% LD slag and 4.1-7.2% distilled carbon of waste tires appears in the range of 89.3-92%. 4) Tbe c chemical composition of the recovered pig iron is 1.7%C, O.05%P, 0.05%S and balance Fe. 5) Tbe recovered dust from the d dust collcctor alter finishing the reduction rcaction appears as a crude zinc oxide conLaining 60% zinc.

• Journal of Life Science
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• v.32 no.2
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• pp.86-93
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• 2022

Lupeol is a type of pentacyclic triterpene and has been reported to have pharmacological activities against various diseases; however, the effect of lupeol on glucose absorption has not been elucidated yet. This study aimed to investigate the effect of lupeol on glucose uptake in 3T3-L1 adipocytes. Lupeol significantly facilitated glucose uptake by translocating glucose transporter type 4 (GLUT4) to the plasma membrane of the 3T3-L1 adipocytes, which was related to activation of the phosphoinositide 3-kinase (PI3K)/protein kinase B (AKT) and 5 'adenosine monophosphate-activated protein kinase (AMPK) pathways. In the PI3K/AKT pathway, lupeol stimulates the phosphorylation of insulin receptor substrate 1 (IRS-1), which activates PI3K. Its activation by lupeol promotes the phosphorylation of AKT, but not the atypical protein kinase C isoforms ζ and λ. Lupeol also promoted the phosphorylation of AMPK. The activation of AMPK increased the expressions of the plasma membrane GLUT4 and the intracellular glucose uptake. The increase in the glucose uptake by lupeol was suppressed by wortmannin (PI3K inhibitor) and compound C (AMPK inhibitor) in the 3T3-L1 adipocytes. The results indicate that lupeol can facilitate glucose uptake by increasing insulin sensitivity through the stimulation of the expression of plasma membrane glucose transporter type 4 via the PI3K/AKT and AMPK pathways in the 3T3-L1 adipocytes.