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버지스-로젠 딜레마와 유명론

  • Lee, Jin-Hui
    • Korean Journal of Logic
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    • v.11 no.1
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    • pp.1-31
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    • 2008
  • 최근 가장 영향력 있는 수학적 실재론과 관련된 논변은 버지스와 로젠의 딜레마이다. 일종의 반-유명론적 논증인 버지스-로젠 딜레마는 유명론자들이 취할 수 있는 제한된 선택지를 제시한 후 그 어느 선택지도 적절하지 못함을 주장하는 것이다. 논자 역시 버지스-로젠 딜레마가 성립한다면 유명론이 가망 없는 전략임에 동의한다. 그러나 논자는 그들의 논의가 유명론 대 실재론이라는 대립구도 대신, 유명론 대 수학 및 과학이라는 잘못된 대립구도를 전제하고 있음을 본 논문을 통해 밝히고자 한다. 간략히 말해, 논자는 버지스-로젠 딜레마는 수학자 및 과학자들의 주장이 글자 그대로 실재론을 함의함을 전제하는데, 이것은 실제 수학 및 과학 활동과 일치하지 않을뿐더러, 이를 입증하기 위해서는 철학적 가정이 개입해야 함을 밝히고, 그 과정에서 유명론의 가능성을 모색하고자 한다. 이러한 논자의 전략은 유명론 진영 안의 특정한 입장을 지지하는 것은 아니다. 버지스-로젠 딜레마는 특정한 유명론의 문제라기보다는 유명론 자체의 가능성과 관련된 것이기 때문이다.

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Insulin-Like Growth Factor-I Induces Androgen Receptor Coactivator Expression in Skeletal Muscle Cells through the p38 MAPK and ERK1/2 Pathways (C2C12 세포에서 insulin-like growth factor-I이 p38 MAPK, ERK1/2 신호전달 경로를 통해 엔드로젠 수용체 coactivator 발현에 미치는 영향)

  • Park, Chan-Ho;Kim, Hye-Jin;Kim, Tae-Un;Lee, Won-Jun
    • Journal of Life Science
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    • v.21 no.2
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    • pp.242-250
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    • 2011
  • Although insulin-like growth factor-I (IGF-I) and androgen receptor (AR) coactivators are well known effectors of skeletal muscle, the molecular mechanism by which signaling pathways integrating AR coactivators and IGF-I in skeletal muscle cells has not been previously examined. In this study, the effects of IGF-I treatment on the gene expression of AR coactivators in the absence of AR ligands and the roles of the p38 MAPK and ERK1/2 signaling pathways in IGF-I-induced AR coactivators induction were examined. C2C12 cells were treated with 250 ng/ml of IGF-I in the presence or absence of specific inhibitors p38 MAPK (SB203580) or ERK1/2 (PD98059). Treatment of C2C12 cells with IGF-I resulted in increased in GRIP-1, SRC-1, and ARA70 protein expression. The levels of GRIP-1, SRC-1, and ARA70 mRNA were also significantly increased after 5min of IGF-I treatment. IGF-I-induced AR coactivator proteins were significantly blocked by pharmacological inhibitors of p38 MAPK and ERK1/2 pathways. However, there was no significant effect of those inhibitors on IGF-I-induced mRNA level of AR coactivators, suggesting that AR coactivators are post-transcriptionally regulated by IGF-I. Furthermore, the present results suggest that IGF-I stimulates the expression of AR coactivators by cooperative activation of the p38 MAPK and ERK1/2 pathways in C2C12 mouse skeletal muscle cells.

Polynigrogen Energetic Materials (폴리나이트로젠 에너지물질)

  • Lee, Junwung
    • Journal of the Korea Institute of Military Science and Technology
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    • v.19 no.3
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    • pp.319-329
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    • 2016
  • Current research trends of prediction of possible structures, synthesis and explosive characteristics of polynitrogen molecules(PNs) are reviewed. Theoretically PNs are composed only of nitrogen atoms, in which N-N bonds are either single or double bonds, and thus when these molecules decompose, release of enormous energy is accompanied. From the middle of 20th century energetic material chemists have been seeking possible structures and the methods of synthesis of these new materials. As a results, from $N_4$ to $N_{60}$ together with their ions are predicted, and experimental chemists have been trying to synthesize these materials with a few success, including the famous ${N_5}^+$ ion in 1999. Although experimental successes are very rare beyond $N_5$ until today, the author believes that renovative ideas together with sincere efforts will bring someday next generation of high energy materials such as nitrogen fullerene($N_{60}$) in reality.

17 $\alpha$-ethinylestradiol 과 nonylphenol에 노출된 송사리에서 vitellogenin 및 estrogen receptor의 발현

  • 이철우;박응로;류지성;남규찬;남성숙;구자민;전성환;나진균;최덕일
    • Proceedings of the Korea Society of Environmental Toocicology Conference
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    • 2001.05a
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    • pp.132-132
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    • 2001
  • Vitellogenin은 난황단백질의 전구체로서 생체내 발현은 에스트로젠과 에스트로젠 수용체가 반응함으로써 활성화되는 것으로 알려져 있다. 어류의 경우 간에서의 vitellogenin의 합성 및 분비는 성숙된 암컷에서만 일어날 수 있는 현상이나, 과거 여러 실험 결과를 바탕으로 수컷이나 미성숙한 암컷에서도 에스트로젠성 물질에 의해 합성이 유도되는 것으로 밝혀졌다. 따라서 수컷 또는 치어 plasma에서 vitellogenin의 측정은 외인성에스트로젠에 대한 노출을 평가할 수 있는 좋은 수단이 될 수 있다. (중략)

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Staudy on Design Management of Rosenthal AG (독일 로젠탈사(社)의 디자인매니지먼트에 대한 고찰)

  • Song, Hyun-Soo;Choi, Sung-Woon
    • The Journal of the Korea Contents Association
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    • v.13 no.9
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    • pp.102-110
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    • 2013
  • To date, the technology competence and design have been understood as the pre-requirements required in the midst of unlimited competition age. It is true that the most of the companies handle the practical or the aesthetic part of the product individually especially in the field of ceramic industry. Accordingly, it is difficult to create the identity of the company. However, the Rosental Co., Ltd in Germany had acquired the corporate identity already by means of the creative process and the design as well from the middle of 1900s and it has been reputed as a company producing the products through the unique design management. Especially, the identity of Rosental has been formed more uniquely with "jury system" verifying not the design results but the development process, independent brand marketing and the experimental mind such as the collaboration with the pure artists. Especially, the participation of the artists to the design development enables to evaluate the ceramic products not only as the simple products for daily life but also as the luxury goods for appreciation and collection. In addition, Rosental shows that the corporate identity may be created not only with the products simply but also completed with the internal external factors of the company through design management skill.

Development and Performance Test of the Kick Motor Igniter (킥모터 점화기 개발 및 성능 시험)

  • Koh, Hyeon-Seok;Kil, Gyoung-Sub;Kim, Byung-Hun;Cho, In-Hyun
    • Aerospace Engineering and Technology
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    • v.6 no.1
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    • pp.190-200
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    • 2007
  • A pyrogen type igniter was designed to satisfy the requirements of KSLV-I Kick Motor system. To insure the reliability of the igniter before the production of the flight model, we have been performed the structure, environmental, combustion tests. The hydraulic test was carried out to confirm the strength of the components of the igniter. The shock and vibration tests were considered to check whether the igniter operates normally under the severe environmental condition. The combustion tests were also performed to understand the ignition characteristics with the variation of initial condition. Finally, we confirmed that the igniter could provide the acceptable energy to ignite the propellant of kick motor at the ground test.

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Axon Extraction Using Vessel Enhancement Filter from a Mitochondria Image Sequence (혈관 증폭 필터를 이용한 미토콘드리아 영상 시퀀스에서의 축색돌기 검출)

  • Hong, Sungmin;Shim, Hackjoon;Chung, Yoojin;Lee, Sang Uk
    • Proceedings of the Korean Society of Broadcast Engineers Conference
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    • 2011.07a
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    • pp.454-455
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    • 2011
  • 미토콘드리아의 수송은 치매, 다형성 경화증, 알츠하이머병 등의 신경성 질환과 관련하여 활발하게 연구되고 있다. 하지만 미토콘드리아 영상의 경우 일반 영상에 비해 노이즈(noise)가 많고 초당 프레임 수(frame-persecond)가 낮기 때문에 분석이 쉽지 않다. 이에 따라 미토콘드리아의 수송 통로인 축색돌기(axon)를 사전에 검출하고자 하는 연구들이 진행되고 있다. 본 논문에서는 이러한 배경을 바탕으로 미토콘드리아 영상에서 축색돌기를 자동으로 분리, 검출해내는 알고리즘을 제안한다. 배경이 비해 밝게 착색되어 있다는 미토콘드리아의 특성을 이용하여 축색돌기를 구분하는 데에 최대 화소값 기법(maximum intensity)과 혈관 증폭 필터(vessel enhancement filter)를 이용한다. 두 기법을 통해 얻은 축색돌기의 파편들은 로젠펠드 세선화(rosenfeld thinning)와 선형 보간법(linear interpolation)을 이용하여 연결되고 최종적인 검출 결과를 얻어낸다. 제시된 실험결과는 영상에서 전체적인 축색돌기가 성공적으로 검출되고 있음을 보여준다.

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Modular System Expressed in Structural System of Fashion Since the Late of 20C -Focusing on the Fashion of Yeohlee Teng, John Ribbe, and Galya Rosenfeld- (20세기후반 이후 패션 구성 방식에 나타난 모듈러 시스템 -욜리 탱, 존 리베, 갈야 로젠펠드 작품을 중심으로-)

  • Yang, Hee-Young
    • Journal of the Korean Society of Clothing and Textiles
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    • v.32 no.5
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    • pp.788-799
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    • 2008
  • Since the late 20C, a lot of fashion designers have considered about new construction system in fashion. Many arguments about architectural form and construction system have being supported on enlargement of range of functionalism fashion through the consideration about new shape and combination among various any other spheres. Modular concept, which is able to divide complex construction of integration into separated basic unit and use various and liberal arrangements, is regarded alternative idea of economic construction that creates new shape and constructive beauty through the simple operation and changing combination continuously. Specially, fashion designs of Yoehlee Teng, John Ribber, and Galya Rosenfeld are estimated that they are effectively utilized architectural modular system pursuing multi-function and multi-change in fashion. Modular system utilized in fashion construction will be classified as follows: 1) layering system of Yoehlee Teng, 2) combine system of john Ribber, and 3) lego system of Galya Rosenfeld. This thesis will presents beneficial guide for simple and practical functionalism fashion design development in 21C.