• Title/Summary/Keyword: 로무스틴

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Long-Term Chemotherapy with Lomustine of Intracranial Meningioma in a Dog (개에서 발생한 두개내 수막종에 대한 로무스틴 치료 증례)

  • Park, Hyung-Jin;Lee, Dae-Yong;Seo, Kyung-Won;Son, Haw-Young;Song, Kun-Ho
    • Journal of Veterinary Clinics
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    • v.29 no.4
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    • pp.328-330
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    • 2012
  • A 13-year-old, neutered male, chihuahua was referred to the Veterinary Medical Teaching Hospital of Chungnam National University with a history of a bilateral mandibular mass, intermittent vomiting, cough, and left sided staggering starting ten days prior. Clinical examination along with radiography, neurologic examination and magnetic resonance imaging (MRI) demonstrated a well-circumscribed and solitary mass in the brain stem. The dura mater was thickened with marked linear enhancement after contrast administration. Based on diagnostic image analysis and histopathologic examination, this case was diagnosed as intracranial meningioma. The patient's symptoms were controlled for 18 months by a combination therapy of prednisolone and lomustine (CCNU), and then he died of at home.

Secondary Brain Tumor Caused by Infiltration of Nasal Neuroendocrine Carcinoma in a Chihuahua Dog: Clinical, Magnetic Resonance Imaging and Histopathological Findings (치와와견에서 발생한 비강 신경내분비암종의 침윤에 의한 이차적인 뇌종양 증례; 자기공명영상과 조직학적 특성)

  • Jung, Dong-In;Kang, Byeong-Teck;Kim, Ju-Won;Kim, Ha-Jung;Park, Hee-Myung
    • Journal of Veterinary Clinics
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    • v.27 no.2
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    • pp.186-189
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    • 2010
  • A 14-year-old neutered female Chihuahua was presented because of seizure episodes and circling to the left side. Based on neurological examination, the lesion was localized on left forebrain. The mass in the left nasal cavity and breaching of the nasal septum were seen magnetic resonance images. And there was a presence of contrast enhanced mass involving the rostral left brain. Based on diagnostic image analysis, this lesion strongly suggested secondary brain tumor infiltrated by nasal cavity. The patient's symptoms were well controlled by a combination therapy of prednisolone and lomustine (CCNU), and survived for two months after diagnosis. This case was definitively diagnosed as a nasal neuroendocrine carcinoma based on histopathological findings. This report describes the clinical findings, imaging characteristics, and pathologic features of secondary brain tumor which caused by infiltration of nasal neuroendocrine carcinoma in a dog.