• Journal of Digital Convergence
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• v.14 no.11
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• pp.607-618
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• 2016

In order to clarify the Gosambaeksunpibokhap-bang(GBBB)'s therapeutic possibility on atopic dermatitis (AD), influences of GBBB on the changes of various immune-related factors and histological changes in NC/Nga mice were evaluated. Experimental results are as follows. Sign of recovery from AD was observed in GBBB treated group with naked eye test. The ratio of white blood cells, neutrophil, lymphocytes, monocyte in blood were decreased to 54%, 63%, 57% and 86% respectively in the GBBB group. IL-4, IL-5, IL-13, Histamine and IgE were significantly decreased to 40%, 80%, 62%, 61% and 57% respectively in the GBBB group. H&E staining showed thickness of epidermis and dermis were decreased by GBBB and inhibited the infiltration of lymphocytes. On the basis of these results, GBBB was confirmed that the possibility as an AD treatment applied externally to the skin. In the further study, immune control mechanism of GBBB will be demonstrated through the additional molecular biological research.

• Journal of Digital Convergence
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• v.14 no.10
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• pp.349-354
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• 2016

The emergence and dissemination of extended-spectrum ${\beta}$-lactamse (ESBL) producing Klebsiella pneumoniae isolates make it more difficult to treatment of bacterial infections. In our study, we detected ESBL genes and investigated antimicrobial susceptibility of K. pneumoniae isolates in Chungcheong province. In addition, clonality among the isolates was analyzed by repetitive element sequence (REP)-PCR. Twenty-one of 102 K. pneumoniae isolates produced CTX-M-14 and/or CTX-M-15 and showed high level (over 70%) resistance to third cephalosporins. CTX-M type ESBL producing K. pneumoniae strains isolated in our study showed diverse clonality and some of the isolates have been disseminated in the community. Enhancing infection control will be needed to prevent dissemination of the K. pneumoniae isolates. In addition, for more effective control of resistant bacteria it is considered necessary to monitor the database constructed through convergence of biological investigation and statistical analysis of antimicrobial resistance genes.

• Electronics and Telecommunications Trends
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• v.35 no.6
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• pp.12-23
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• 2020

Because of economic polarization and difficulties, extreme personalization, and the complexity of social relationships, modern people are experiencing various mental disorders or pathologies. Accordingly, there is an urgent need to prepare more active countermeasures and support those with mental health difficulties to improve mental health and prevent abnormal pathologies. Artificial intelligence (AI) is expected to improve the mental health of individuals through emotional enhancement beyond affective computing. We investigated how to use AI to prevent and diagnose mental diseases or disorders, support treatment, and manage followup. In particular, promising services that can be used in daily life or medical clinics were discovered and active directions for realizing these services are suggested.

• Journal of Convergence for Information Technology
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• v.10 no.3
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• pp.7-15
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• 2020

As the paradigm shifts from treatment and provider-centered healthcare to prevention and consumer-centered healthcare, the integration of ICT convergence technology is calling for an era of digital healthcare industry revival in the Fourth Industrial Revolution. It is possible to provide individual customized medical services utilizing various medical data, and it is possible to provide various medical services that transcend time and space through integration with other industries. Such digital healthcare includes health, nutrition, exercise, and patient care, while the digital healthcare industry includes healthcare and IT related to medical devices, medical information systems, and healthcare platforms that can provide personal health and medical information. Due to the social demands of the aging and the increase of chronic diseases, digital healthcare is considered as an important policy in the fourth industrial revolution in Korea. In order for the digital healthcare industry to contribute to the prolongation of human life and the improvement of quality of life, it is urgent to develop related infrastructures, legal institutions, and prepare policies. In addition, it is important to activate convergent education to foster talents who will lead the digital healthcare industry. The purpose of this study was to examine the trends of the digital healthcare industry in the era of the fourth industrial revolution and the direction of government R & D policies, and to derive directions and suggestions for future development.

• Journal of Digital Convergence
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• v.17 no.8
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• pp.249-255
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• 2019

Type 2 diabetes mellitus(T2DM) is included in metabolic disorders characterized by hyperglycemia, which causes many complications, and requires long-term treatment resulting in massive medical expenses each year. There have been many studies to solve this problem, but the existing studies have not been accurate by learning and predicting the data at specific time point. Thus, this study proposed a model using RNN to increase the accuracy of prediction of T2DM. This work propose a T2DM prediction model based on Korean Genome and Epidemiology study(Ansan, Anseong Korea). We trained all of the data over time to create prediction model of diabetes. To verify the results of the prediction model, we compared the accuracy with the existing machine learning methods, LR, k-NN, and SVM. Proposed prediction model accuracy was 0.92 and the AUC was 0.92, which were higher than the other. Therefore predicting the onset of T2DM by using the proposed diabetes prediction model in this study, it could lead to healthier lifestyle and hyperglycemic control resulting in lower risk of diabetes by alerted diabetes occurrence.

• Proceedings of the Korean Vacuum Society Conference
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• 2013.08a
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• pp.290.2-290.2
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• 2013

X-선 튜브는 의료 영상 및 치료, 산업용 제전 장치, 비파괴 X-선 영상 장치 등에서 사용되는데 기존의 열전자원을 이용한 X-선 튜브와는 달리, 냉음극형 X-선 튜브는 빠른 속도의 디지털 구동이 가능하며 전력 소비가 낮은 장점이 있다. 따라서, 최근 많은 연구자들에 의해서 냉음극형 X-선 튜브에 관한 연구가 활발하게 진행되고 있다. 냉음극형 X-선 튜브는 전계 방출을 이용한 전자원을 사용하며, 탄소나노튜브 (CNT), Si, 다양한 종류의 나노선 등이 대표적이다. 그 중에서 CNT는 높은 종횡비로 인해 전계 방출 특성이 우수하여 가장 대표적인 물질이다. CNT를 이용한 전자원을 제작하기 위해서는 직접 성장법, 전기영동법, 스크린 프린팅법, 디핑법 등 다양한 방법이 존재한다. 직접 성장법을 제외한 방법들은 모재료인 CNT와 용매, 금속재료들을 섞어 페이스트나 수용액의 상태를 제작하여야 한다. 이 때, 금속 재료는 기판과 CNT간의 접착 및 전자 전도 통로의 역할을 하는 무기 충전제이며 일반적으로 나노 혹은 수 마이크로미터 크기의 상태로 존재하는 것을 주로 사용한다. X-선 튜브 제작은 일반적으로 외벽을 유리 혹은 세라믹을 주로 사용하는데 아노드 전극 및 캐소드 전극 등과 결합하여 진공 밀봉된 형태가 되어야 한다. 브레이징 방법은 금속과 세라믹을 결합하는데 매우 유용한 방법이며, 그 중에서도 진공 브레이징 방법은 다량의 부품을 한 번에 결합시킬 수 있다. 하지만 진공 브레이징 공정의 온도는 약 $700{\sim}1,000^{\circ}C$이며 이는 금속 재료가 충분히 증발할 수 있는 온도가 된다. 본 발표에서는 고온 진공 상태에서의 무기 충전제의 증발에 대한 현상을 관찰하고 고온진공 상태에서 증발없이 무기 충전제로의 역할을 할 수 있도록 다양한 금속 및 합금에 대한 연구를 수행하였다. 또한, 이 연구를 통해 선택된 무기 충전제를 포함하여 CNT 페이스트를 볼밀링 방법을 이용하여 제작하였으며, 이를 이용한 CNT 에미터가 X-선 튜브의 전자원으로 사용될 수 있는지 확인하기 위해 전계 방출 실험을 함께 실시하였다. 제작된 CNT 에미터가 우수한 전계 방출 특성을 가지고 있음을 확인하였으며, 이는 본 연구를 통해 선택된 금속 및 합금 재료가 무기 충전제로의 역할을 잘 수행하고 있음을 보여준다.

• Journal of Korea Entertainment Industry Association
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• v.15 no.4
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• pp.325-335
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• 2021

Chronic diseases have been increasing recently as the average life expectancy of humans has been extended, and this trend has caused problems such as the widespread demand for health and rehabilitation services and rising medical costs. In order to solve this problem, the community-based rehabilitation has been developed and strengthened in Korea and gradually promoted since 2019. It is important to secure access to clients who want to use services to revitalize community-based rehabilitation. So in this study, as part of the community-based rehabilitation, intends to devise smartphone applications designs and develop a prototype to secure access to community-based occupational therapy services based on occupation and activities. For Occupational Therapy Practice Framework (OTPF), International Classification of Functioning, Disability and Health (ICF), and Allen Diagnostic Module-2 (ADM-2) were used to devise and categorize occupation and activity based application content, and link OTPF, ICF, and ADM-2 through prior research analysis and expert meetings. The derived content was visualized through literature review and activity analysis, and was implemented to enable direct playback within the application using the YouTube API, and finally developed a prototype application. The Android Studio 3.5.2 for Windows 64-bit was used to build the application prototype. In further research, converging various digital technologies for user convenience and additionally researching community-based occupational therapy service providers opinions and service user satisfaction will improve accessibility to community-based occupational therapy services for clients who have difficulty occupational performance in the community.

• Journal of the Institute of Convergence Signal Processing
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• v.21 no.4
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• pp.195-201
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• 2020

This study studied scoliosis, one of the most common modern diseases caused by lifestyle patterns of office workers sitting in front of computers all day and modern people who use smart phones frequently. Scoliosis is a typical complication that takes more than 80% of the nation's total population at least once. X-ray are used to test for these complications. X-ray, a non-destructive testing method that allows scoliosis to be easily performed and filmed in various areas such as the chest, abdomen and bone without contrast agents or other instruments. We uses NI DAQ to miniaturize digital X-ray imaging devices and image intensifier in self-shielding housing with Vision Assistant for drawing lines to the top and the bottom of the spine to acquire angles, i.e. curvature in real-time. In this way, the research was conducted to see scoliosis patients and their condition easily and to help rapid treatment for solving the problem of posture correction in modern people.

• Journal of Korean Physical Therapy Science
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• v.30 no.4
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• pp.92-110
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• 2023

Background: Digital therapeutics are software medical devices that provide evidence-based treatments to prevent, manage, and treat disease. Digital therapies have recently been shown to be effective in motivating children with cerebral palsy as a tool in neuropsychological therapy. Digital therapies improve postural control, balance and gait in children with cerebral palsy. Therefore, this study aims to investigate the effects of digital therapies on balance and gait in children with cerebral palsy and to provide guidelines for prescribing digital therapies for children with cerebral palsy. Design: A Systematic Review Methods: This study searched for English-language articles published in medical journals from January 2000 to July 2023 using PubMed and MEDLINE based on the year of initiation of the digital therapy. The search terms used in the study were 'digital technology' OR 'digital therapeutic' OR 'mobile application' OR 'mobile health' OR 'virtual reality' OR 'game' AND 'cerebral palsy', 'balance' 'gait' as the main keywords. The final article was assigned an evidence level and a Physiotherapy Evidence Database (PEDro) score to assess the quality of clinical trials studies. Results: The digital therapies applied to improve balance and gait in children with cerebral palsy are game-based virtual reality training and the Nintendo Wii Fit program. Both digital therapy interventions had a significant effect on improving balance in children with cerebral palsy, and virtual reality training significantly improved balance and gait. However, there were no significant improvements in balance and gait within two weeks of treatment, regardless of the type of digital intervention. Conclusion: The study suggests that this data will be important in building the evidence base for the effectiveness of digital therapies on balance and gait in children with cerebral palsy and in advancing clinical protocols.

• The Journal of Korean Academy of Prosthodontics
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• v.61 no.4
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• pp.316-327
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• 2023

In the case of fully edentulous patients with severe alveolar bone resorption, the consideration of 'All-on-X' implant-supported fixed prosthesis after placing four or more implants in the anterior maxilla is possible. Recent advancements in digital dentistry have enabled systematic and predictable treatment in all phases, including diagnosis, surgery, and prosthesis fabrication. By incorporating digital dentistry techniques such as digital complete denture, implant surgical guides, facial scanning into the conventional restoration process, it is possible to reduce the complexity of the prosthesis fabrication and effectively achieve the transition from provisional prosthesis to definitive prosthesis in terms of both aesthetics and function.