• Maxillofacial Plastic and Reconstructive Surgery
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• v.19 no.4
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• pp.377-382
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• 1997

Miniplate의 사용은 Champy등의 보고 이후 구강외과 영역에 있어서 외상 혹은 악교정수술등 많은 분야에 이용되기 시작했다. 전통적인 악간고정 방법에 비해 miniplate는 사용하기 쉽고, 정확한 해부학적 정복 및 고정을 가능케 하며 결과적으로 빠른 치유를 가능케 한다는 장점들을 갖고 있다. 그러나 감염, wound dehiscence, 부식, 나사의 헐거워짐, 주위조직의 변색 그리고 stress shielding effect등의 후유증들이 보고되어 왔으며 가장 무해한 금속이라고 알려진 titanium 또한 주위조직 및 lung, spleen, liver 그리고 kidney 등과 같은 조직으로 metal을 전이시키는 것으로 보고되고 있다. 특히 안와골 주변과 같은 상부 연조직이 얇은 곳에 miniplate를 사용할 경우 miniplate가 만져지거나 보일수도 있다는 점이 보고되었으며 따라서 술후 사용되었던 miniplate를 제거 해야만 할 것인가가 또한 주된 관심사로 보고되고 있다. 이에 저자는 이러한 금속성 miniplate의 단점을 개선하고자 자가 두개골을 이용한 플레이트를 고안하였다. '자가 두개골 플레이트'의 적응증은, enophthalmos 개선의 목적으로 두개골을 채취해 임플란트로 사용하는, enophthalmos를 동반한 관골 및 안와골의 복합골절환자에 있어 두개골의 추가채취가 가능한 경우가 될 수 있겠다. 자가 두개골을 이용해 플레이트를 고안하려고 본 증례에서의 시도는 구강외과 영역에 있어서 자가 두개골이 골편이 고정재료로도 쓰일 수 있다는 가능성을 보여주었다는 점에서 의미가 있다고 저자는 생각한다.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 1998.05a
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• pp.216-221
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• 1998

슈퍼임포즈는 개인식별 방법으로 신원 미상의 두개골의 발견 시, 두개골의 사진과 용의자 생전 사진의 동일 비율로 확대, 축소 후 두 영상을 중첩하므로서 동일인 여부를 비교, 판별하는 기법이다. 삼풍백화점 붕괴사고와 Guam KAL기 추락사고와 같이 대형사건에서의 개인식별에 매우 중요한 문제이다. 본 연구는 비디오 카메라로 입력한 두개골 영상과 스캐너로 입력한 생전 사진의 중첩을 위한 H/W 시스템의 구축과 영상처리 기법을 응용한 응용 프로그램을 개발하였다 슈퍼임포즈의 영상처리 기법으로는 두개골 및 생전 사진의 윤곽선 추출, 중첩점 조정, 상,하,좌,우 각도조정, 윤곽선보정, Hue 조정, 히스토그램 조정 등 다양한 영상처리 기법을 응용하였다. 또한, 이들 영상처리기법은 법의학 체제에 입각한 슈퍼임포즈 영상합성이 개인식별 감정시 필요한 최적의 영상 비교가 가능하도록 DB 시스템 구축과 분석시스템을 개발하였다. 그리고, 실제 감정시 본 영상시스템으로 감정해 본 결과로 보다 정확하고 실시간으로 감정이 가능하다. 본 슈퍼 임포즈 영상시스템은 슈퍼 임포즈 영상자료의 처리와 축적 기술의 발전으로, 두개골 영상과 생전 사진을 이용한 생전의 3차원 실 영상의 복원연구가 가능하리라 사료된다.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.2 no.1
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• pp.3-10
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• 1998

In this paper, a new superimposition scheme using a computer vision system was proposed with 7 pairs of skull and ante-mortem photographs, which were already identified through other tests and DNA fingerprints at the Korea National Institute of Scientific Investigation. At this computer vision system, an unidentified skull was caught by video-camcoder with the MPEG and a ante-mortem photograph was scanned by scanner. These two images were processed and superimposed using pixel processing. Recognition of the individual identification by anatomical references was performed on the two superimposed images. This image processing techniques for the superimposition of skull and ante-morterm photographs simplify used the previous approach taking skull photographs and developing it to the same size as the ante-mortem Photographs. This system using various image Processing techniques on computer screen, a more precise and time-saving superimposition technique could be able to be applied in the area of computer individual identification.

• Journal of Digital Convergence
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• v.11 no.9
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• pp.365-370
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• 2013

This mouse calvarial defected model is frequently used for new scaffold development in the bone regeneration. Most experiments are carried out in this way by measuring the bone regeneration of mouse calvaria defected area. As a next step, hematoxylin and eosin staining is analyzed by sacrificing mice On the other hand, the quantitative analysis for bone regeneration is carried out by micro computed tomography. However, there are several drawbacks with the micro computed tomography. That is, it takes a long time and it is quite expensive for bone regeneration quantitative analysis. This study was performed by simply measuring the quantity of bone regeneration in mouse clavaira defected area on two-dimensional digital x-ray images via Image J. Consequentially, this experimental method by using J program might help bio-technologist researcher regarding new bone regeneration by comparing the quantity of bone regeneration quickly and precisely as well.

• Journal of Korean Academy of Oral and Maxillofacial Radiology
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• v.24 no.2
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• pp.317-326
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• 1994

Panoramic radiographs of a dry skull were used to evaluate the accuracy of four panoramic dental X-ray systems in determining tooth angulations in the buccal segments. The four machines evaluated were the Philips Oralix Pan DC, the GE panelipse, the SS White panorex 1, and the SS White Panorex 2. Panoramic radiographs were taken at six different patient positions for each machine to evaluate the effects of patient positioning on determining tooth angulations in the buccal segments. All of the machines studied showed a significant correlation between the mean radiographic estimates and the actual measurements regardless of positioning(p<0.05). With correct placement of the skull, the results were analyzed for an error tolerance of +/-3/sup 0/ between the actual measurements and the radiographic estimates for tooth angulation. The SS White Panorex 1 was accurate 74% of the time, the GE Panelipse was accurate 67% of the time, the Philips Oralix Pan DC and the SS White Panorex 2 were accurate 64% of the time. When an error tolerance of +/-5/sup 0/ was permitted, the accuracy was 89% for the SS White Panorex 1 and the GE Panelipse, 85% for the Philips Oralix Pan DC, and 81% for the SS White Panorex 2.

• The Korean Journal of Nuclear Medicine
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• v.24 no.1
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• pp.138-144
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• 1990

두개골과 신장에 골스캔재제의 미만성 섭취증가를(Hot Skull, Hot Kidney) 항암제투여를 받은 4례의 암환자와 검상적혈구 빈혈환자에서 발견하여 추적 관찰하였다. Hot Kidney는 항암제 투여후 관찰되어 항암제투여를 중단한 후 소실되었으나, Hot Skull은 항암제 투여와 관계없이 시간이 경과함에 따라 변화가 없거나 점차 진전되었다. 겸상적혈구 빈혈환자 1례에서 두개골, 신장, 비장에 증가된 섭취를 보였고 30개월동안 추적관찰하였으나 섭취정도에 변화가 없었다. 결론적으로 항암제의 투여는 골스캔재제의 신장섭 취를 증가시키나 두개골 섭취에는 영향을 미치지 않은 것으로 관찰되었다.

• Journal of the korean academy of Pediatric Dentistry
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• v.30 no.2
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• pp.217-228
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• 2003

Co-ordinate growth of the brain and skull is achieved through a series of tissue interactions between the developing brain, the growing bones of the skull and the sutures that unite the bones. Craniosynostosis, the premature fusion of cranial sutures, presumably involves disturbance of these interactions. Bmp2, one of bone morphogenetic proteins (Bmps), is involved in the regulation of the shapes of individual bones and the relative proportions of the skeleton. Mutations in the homeobox gene Msx2, known as a downstream gene of Bmp, cause Boston-type human craniosynostosis. The phenotype of Dlx5 homozygote mutant mouse presents craniofacial abnormalities including a delayed ossification of calvarial bone. These facts suggest important roles of Bmp2, Msx2 and Dlx5 genes in the cranial bone growth and suture morphogenesis. To elucidate the function of these molecules in the early morphogenesis of mouse cranial sutures, we first analyzed by in situ hybridization the expression of Bmp2(E15-18), Msx2 and Dlx5 genes in the developing sagittal suture of calvaria during the embryonic stage. Bmp2 mRNA was intensely expressed in the osteogenic fronts and also at the low level in the periosteum of parietal bones during embryonic stage, Msx2 mRNA was intensely expressed in the sutural mesenchyme and mildly expressed in the dura mater during the embryonic stage. Dlx5 mRNA was intensely expressed osteogenic fronts and parietal bones. To further examine the role of Bmp signaling in cranial suture, we did in vitro experiments in E15.5 mouse calvarial explants. Interestingly, implantation of Bmp2-soaked beads onto the osteogenic fronts after 48 hours organ culture resulted in the increase of the tissue thickness and cell number around Bmp2 beads, compared to BSA control beads. In addition Bmp2 induced etopic expressions of Msx2 and Dlx5 genes. On the other hand, overexpression of FGF2 did not induce the expression of Msx2 and Dlx5. Taken together, these data indicate that Bmp2 signaling molecule has a important role in regulating the cranial bone growth and early morphogenesis of cranial suture. We also suggest that Bmp signaling is involved in all the stages of osteogenesis of cranial bones and the maintenance of cranial suture by regulating Msx2 and Dlx5 genes, and that Msx2 and Dlx5 genes are specific transcription factors of Bmp signaling pathway.

• The korean journal of orthodontics
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• v.32 no.6 s.95
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• pp.425-434
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• 2002

The purpose of this investigation was to study the spatial changes of the maxillofacial complex following maxillary protraction transmitted to the center of resistance of a dry juvenile human skull by a modified maxillary protraction appliance. Four dry juvenile human skulls (without mandible) with well aligned upper deciduous dentition and early mixed dentition were used as experimental samples. A modified protraction headgear was fabricated from a Delare's facemask, and following an alginate impression, an orthodontic resin maxillary splint was made for each dry skull. Protraction force level was maintained at approximately 1000gm per side for 6 hours. Cephalometric radiographs were taken pre- and post- protraction, and nine reference markers with 1.5 mm length of $.017\times.025$ TMA wire were placed on the right side of the skull for an accurate superimposition of serial cephalometric radiographs. The present investigation demonstrated that vertical changes associated with an anterior displacement of the maxillary complex was observed, and the most prominent effect of protraction headgear was a counterclockwise rotation of the maxilla, that is, a forward and downward tipping around the palatomaxillary region.

• Journal of the Korean Society of Radiology
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• v.84 no.5
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• pp.1080-1090
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• 2023

Purpose This study aimed to compare the volume and normative percentiles of brain volumetry in the Korean population using quantitative brain volumetric MRI analysis tools NeuroQuant^Ⓡ (NQ) and DeepBrain^Ⓡ (DB), and to evaluate whether the differences in the normative percentiles of brain volumetry between the two tools is related to cranial shape. Materials and Methods In this retrospective study, we analyzed the brain volume reports obtained from NQ and DB in 163 participants without gross structural brain abnormalities. We measured threedimensional diameters to evaluate the cranial shape on T1-weighted images. Statistical analyses were performed using intra-class correlation coefficients and linear correlations. Results The mean normative percentiles of the thalamus (90.8 vs. 63.3 percentile), putamen (90.0 vs. 60.0 percentile), and parietal lobe (80.1 vs. 74.1 percentile) were larger in the NQ group than in the DB group, whereas that of the occipital lobe (18.4 vs. 68.5 percentile) was smaller in the NQ group than in the DB group. We found a significant correlation between the mean normative percentiles obtained from the NQ and cranial shape: the mean normative percentile of the occipital lobe increased with the anteroposterior diameter and decreased with the craniocaudal diameter. Conclusion The mean normative percentiles obtained from NQ and DB differed significantly for many brain regions, and these differences may be related to cranial shape.

• Proceedings of the Costume Culture Conference
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• 2004.04a
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• pp.75-77
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• 2004

머리형태의 근간이 되는 두개골의 형태는 두개골이 나타내는 선에 따라 인종적 특징을 뚜렷이 나타낼 뿐 아니라 같은 집단 내에서도 개인차가 크며 복잡한 곡면구조를 가지고 있다. 더욱이 머리 형태는 두개부 뿐만 아니라 얼굴부위와 연결되어 매우 세밀하고 복잡한 구조를 지니고 있을 뿐 아니라, 인간의 생명과 직결된 매우 중요한 부위이다. 그러므로 모자와 헬멧을 비롯하여 고글, 안전모, 안경 등 머리 및 얼굴에 착용되는 산업제품의 안전하고 유용한 설계를 위하여 이러한 부위들의 정확한 치수와 형태파악을 필요로 한다. (중략)