• Title/Summary/Keyword: 델

Search Result 221, Processing Time 0.023 seconds

Development and Application of Development Principles for Clinical Information Model (임상정보모델 개발원칙의 개발과 적용)

  • Ahn, Sun-Ju
    • Journal of the Korea Academia-Industrial cooperation Society
    • /
    • v.11 no.8
    • /
    • pp.2899-2905
    • /
    • 2010
  • To be applicable under electronic health record system in order to ensure semantic interoperability of clinical information, the development principle for clinical information model to reflect objective and function is required. The aim of this study is to develop the development principles for clinical information model and evaluate the Clinical Contents Model. In order to develop the principle, from November 2008 to March 2009, the surveys about 1) definition, 2) function and 3) quality criteria were done, and 4) the components of advanced model were analyzed. The study was processed in 3 levels. Firstly in the development level, key words and key words-paragraph were driven from the references, and the principles were drawn based on the clinical or functional importance and frequency. In the application level, the 3 experts of clinical information model assessed 30 Clinical Contents Models by applying it. In the feedback level, the Clinical Contents Model in which errors were found was modified. As the results, 18 development principles were derived with 3 categories which were structure, process and contents. The Clinical Contents Models were assessed with the principles, and the 17 models were found that they did not follow it. During the feedback process, the necessity of the advanced education of the principle and the establishment of the regular quality improvement strategy to use it is raised. The proposed development principle supports the consistent model-development between clinical information model developers, and could be used as evaluation criteria.

A Baseline Correction for Effective Analysis of Alzheimer’s Disease based on Raman Spectra from Platelet (혈소판 라만 스펙트럼의 효율적인 분석을 위한 기준선 보정 방법)

  • Park, Aa-Ron;Baek, Sung-June
    • Journal of the Institute of Electronics Engineers of Korea CI
    • /
    • v.49 no.1
    • /
    • pp.16-22
    • /
    • 2012
  • In this paper, we proposed a method of baseline correction for analysis of Raman spectra of platelets from Alzheimer's disease (AD) transgenic mice. Measured Raman spectra include the meaningful information and unnecessary noise which is composed of baseline and additive noise. The Raman spectrum is divided into the local region including several peaks and the spectrum of the region is modeled by curve fitting using Gaussian model. The additive noise is clearly removed from the process of replacing the original spectrum with the fitted model. The baseline correction after interpolating the local minima of the fitted model with linear, piecewise cubic Hermite and cubic spline algorithm. The baseline corrected models extract the feature with principal component analysis (PCA). The classification result of support vector machine (SVM) and maximum $a$ posteriori probability (MAP) using linear interpolation method showed the good performance about overall number of principal components, especially SVM gave the best performance which is about 97.3% true classification average rate in case of piecewise cubic Hermite algorithm and 5 principal components. In addition, it confirmed that the proposed baseline correction method compared with the previous research result could be effectively applied in the analysis of the Raman spectra of platelet.

Synthesis of Hyper Crosslinked Polymer Particle Having Hydroxyl Group (하이드록시기를 갖는 Hyper Crosslinked 고분자 입자의 합성)

  • Jeon, Hyo-Jin;Kim, Dong-Ok;Park, Jea-Sung;Kim, Jong-Sik;Kim, Dong-Wook;Jung, Mi-Sun;Shin, Seong-Whan;Lee, Sang-Wook
    • Polymer(Korea)
    • /
    • v.35 no.1
    • /
    • pp.66-71
    • /
    • 2011
  • With the synthesis of hyper crosslinked polymer particle (HCPP), having microporous structure with hydroxyl functional group, synthesized via polymerization reaction consists of three stepssuspension polymerization, hyper crosslinking by Friedel-Craft catalysis and hydrolysis reaction, the effects of the ratio of each monomer, hyper crosslinking conditions and $CO_2$ supercritical drying on the variations of surface morphology, pore size & distribution and BET surface area of HCPP have been investigated. It was observed that the formation of surface crack or fracture of HCPP was intimately related with the degree of hyper crosslinking reaction between microphase separated domains. And the value of BET surface area of HCPP increased with the increase of reaction temperature, time and the amounts of solvent used in hyper crosslinking step. Moreover, $CO_2$ supercritical drying was proven to be a very effective method for removing stabilizer, unreacted monomers and oligomers from HCPP but needed to add methanol as a co-solvent for efficient removing of residual catalyst.

Development of the Imaging Optical System for the 545 nm Fluorescent Plate of X-ray (X선용 545 nm 형광판 결상광학계 개발)

  • Lee, Dong-Hee
    • Journal of Korean Ophthalmic Optics Society
    • /
    • v.13 no.2
    • /
    • pp.17-22
    • /
    • 2008
  • To develop an imaging optical system for the 545 nm fluorescent plate of X-ray. Methods: We designed and manufactured a new imaging optical system for the 545 nm fluorescent plate of X-ray by Sigma 2000 program after deciding the design comparison standards referred to Canon CX2-70 model. Results: The characteristics of the new imaging optical system for the 545 nm fluorescent plate of X-ray have the magnification of -0.225x, the image field size of $90mm{\times}90mm$, and the 0.033 mm resolution line width at the 30% MTF value criterion. These mean that the new model has a capability of deciphering for the more large screen and the resolution of deciphering is superior to that of Canon CX2-70 model. Also the image side NA (-0.196) of the new model is about $\sqrt{2}$ times than that (-0.139) of CX2-70 and the object side NA (0.044) of the new model is about 2 times than that (0.022) of CX2-70. These mean that the sensitivity of the film in the new design model is able to be increased to about 4 times and there is the possibility of reducing the bombed time of X-ray to 1/4 times. Conclusions: We could design and manufacture the imaging optical system for the 545 nm fluorescent plate of X-ray having the possibility of reducing the bombed time of X-ray to 1/4 times in comparision to Canon CX2-70 model, the characteristics of which have the image field size of $90mm{\times}90mm$ and the MTF of 30% or more at 15 lines/mm criterion.

  • PDF

Chloride Binding Properties of Portland Cement Binder Incorporating CaAl2O4-CaAl4O7 (CaAl2O4-CaAl4O7 혼입 포틀랜드 시멘트 결합재의 염소이온 고정 특성)

  • Han, Jae-Doh;Lee, Yun-Su;Lee, Han-Seung
    • Journal of the Korea institute for structural maintenance and inspection
    • /
    • v.24 no.4
    • /
    • pp.1-9
    • /
    • 2020
  • This study conducted to understand effects of CA (CaAl2O4) and CA2 (CaAl4O7) ratio on chloride binding ability and compressive strength and pore structure of cement mortar incorporating mixture of CA and CA2. The Portland cement based specimens were mixed with the clinkers CA and CA2, and these calcium aluminate clinker mixture were replaced 0, 5, 10% by weight of cement. After all the test specimens were cured for 28 days under water curing, they were immersed in the distilled water and NaCl solution. As a result, 28 days compressive strength of all specimens was similar, and As the replacement ratio of calcium aluminate clinker in the specimen increased, Friedel's salt production tended to increase. However, it was dependent on the amount of Al2O3 in the level of 5% replacement and CA ratio in the level of 10% replacement. Through equilibrium isotherm result, it was also indicated that as replacement ratio of calcium aluminate clinker in cement matrix increased, chloride binding capacity was improved, and chloride penetration was suppressed. In this study, the specimen replaced with 10% of the calcium aluminate clinker mixture (CA 39%, CA2 60%) was remarkable to control chloride attack. We figured out necessity to understand optimal CA/CA2 ratio to effectively apply CA2 as a sustainable building material by improving the chloride binding ability in Portland cement based system.

Affect and Cognition Interface in Aesthetic Experiences of Landscapes (경관의 미학적 경험에 있어서 감정과 인지의 상호작용)

  • 이영경
    • Journal of the Korean Institute of Landscape Architecture
    • /
    • v.20 no.3
    • /
    • pp.11-20
    • /
    • 1992
  • 본 논문에서는 사람이 환경을 통해 경험하는 미학적 경험(aesthetic experience)을 체계화시킨 이론적 모델(a conceptual model of affect and cognition interface in aesthetic experiences of landscapes)이 간단히 소개 되며, 이 모델을 검증하기 위한 연구가 중점적으로 다루어진다. 제시된 모 델은 경관의 미학적 경험을 감정(affect)과 인지(cognition)와의 상호작용 (interface)으로 설명하고 있으며, 세 가지 요소(사람이 환경에 대하여 갖고 있는 목적 : tasks, 사람의 모든 과거경험에 근거한 지식일체 : schematic knowledge, 환경의 독특한 상황 : environmental situation)를 미학적 경험 의 주요인자로 제시한다. 이 모델을 검증하기 위한 연구에서는 앞에서 소 개된 미학적 경험의 세 가지 요소(사람의 목적, 지식, 환경상황)를 과학적 이고 계량적이고 처리할 수 있도록 세부요소로 분류정의 (operationalization)하였다. 구체적으로, 사람의 목적은 환경을 평가하는 세 가지 목적, 즉 경치평가(scenic beauty judgment), 들놀이 목적으로서의 평가(picnic preference judgment), 주거목적으로서의 평가(living preference judgment)로 분류되었고, 이 세 가지 환경평가는 미학적 경험의 지표로 사용되었다. 사람의 지식은 국적에 근거한 문화적인 지식(cultural schema : 한국인과 텍사스인)과 직업에 근거한 사회적인 지식(social schema : 농부, 비농부, 조경학과 학생)으로 분류되었으며, 환경상황은 환 경의 아름다움(beauty : 아름다운 경관과 아름답지않은 경관)과 환경의 의 미(meaning : 긍정적인 의미가 있는 한국경관, 긍정적인 의미가 없는 한국 경관, 긍정적인 의미가 있는 미국 텍사스경관)로 분류되었다. 연구결과를 보면, 이론적 모델에서 소개된 세 가지 요소들 (사람의 목적, 지식, 환경상 황) 모두가 경관의 미학적 경험에(경치평가, 들놀이 선호도, 주거지 선호 도) 중요한 역할을 하는 것으로 밝혀졌으며, 이 연구결과는 제시된 이론적 모델을 뒷받침하고 있다. 특히, 가장 흥미로운 연구결과를 요약하면 첫째, 사람의 문화적인 지식은 단독으로 미학적 경험에 영향을 주는 것이 아니라 다른 요소들(특히 사회적인 지식과 목적)과의 상호작용을 통해 미학적 경 험을 형성한다는 것으로 밝혀졌다. 둘째, 환경의 아름다움은 다른 세부요소 들(환경의 의미, 사람의 목적과 지식)보다 미학적 경험에 주는 영향이 큰 것으로 나타났으며, 모든 사람들에게 비슷한 미학적 경험을 발생시키는 것 이 밝혀졌다. 다시 말하면 모든 사람들은 그들의 문화적인 국적과 사회적 인 직업의 차이, 목적의 차이, 또한 환경의 의미의 차이에 상관없이 아름다 운 경관(High-beauty landscape)을 주거지나 나들이 장소로서 선호했으며, 아름답다고 평가했다. 반면에, 사람들이 갖고 있는 문화의 차이, 직업의 차 이, 목적의 차이, 그리고 환경의 의미의 차이에 따라 경관의 미학적 평가가 달라진 것으로 나타났다.

  • PDF

항만개발에 의한 조석조류 및 수질변화 예측을 위한 시뮬레이션 모델 연구

  • 박석순;김소연;이진희
    • Proceedings of the Korea Society for Simulation Conference
    • /
    • 1997.04a
    • /
    • pp.114-114
    • /
    • 1997
  • 항만개발 사업은 매립이나 준설과 같은 해안선과 해저지형을 변화시키는 공사가 이루어지며 이는 조석조류 현상의 변화를 유발하게 된다. 특히 해안지형이 복잡한 항만이나 하구에서는 변화정도가 크게 나타나며 방파제나 선박접안 시설과 같은 항내 구조물을 축조 할 경우에도 조석조류 변화가 야기된다. 조석조류 현상의 변화는 해양 수질과 생물상에 영 향을 줄뿐만 아니라 인접한 육지에 이르기까지 크다란 피해를 유발할 수가 있다. 창조시 해 수를 육지로 범람하게 하거나 퇴적이나 침식조건을 변화시킬 수도 있으며 오염물질이 외해 로 확산되는 과정을 방해하고 해양생물의 서식조건을 악화시켜 부근 해역의 어업에 피해를 유발할 수도 있다. 또한 해안 공사 과정에 해수로 유입되는 토사나 항만 이용시에 배출되는 폐수 등이 항내 수질과 생태계를 변화시킬 수 있다. 따라서 조석조류와 수질변화를 사전에 예측하고 이를 최소화하는 방안이 강구되어야 한다. 조석조류와 수질 변화를 사전에 예측하 는 방법으로 축소모형 실험과 컴퓨터 시뮬레이션이 사용된다. 축소모형 실험은 현장을 재현 하는데 많은 경비와 시간이 소모되며 예측에 한계가 있다. 반면에 컴퓨터 시뮬레이션은 대 상해역의 지형과 조류 그리고 수질특성에 적합하게 모델을 개발할 경우 예측력이 매우 높기 때문에 현재 가장 널리 이용되고 있다. 본 연구는 유한 요소법에 기초하여 미국 공병단 (United States Army Corps of Engineers)에서 개발한 TABS-2 모델을 이용하여 온산항에 서 시행되는 부두건설에 따른 조석조류 및 수질변화를 시뮬레이션하였다. 측정된 자료로 모 델 계수를 보정하고 검증하였으며 항내 매립과 준설이 이루어질 때 나타나는 조위와 조속변 화를 예측하였다. 매립과 준설공사시 유출되는 토사가 조석조류현상에 따라 이동 확산되는 범위와 농도분포를 예측하였다.ophobic components)은 75~80%, 친수성 물질(hydrophilic components)은 30~33%정도의 분포를 보였고, 전염소 및 전오존 공정을 거친 처리수에서는 각각 62.2-62.8%, 43.9~49.0% 및 50~ 55%, 40~57% 정도의 분포를 보였다. 그리고 웅집-침전을 거친 처리수에서는 그 분포가 77~82%, 24-48%였다. 전주리 공정을 통하여 소수성 물질(byoghobic components)의 분포가 감 소하는 것을 볼 때 전염소 및 전오존 처리가 용존유기물의 응집에는 오히려 역 효과를 나타내는 것으로 판단된다. 것으로 판단된다.여 황토 2g에 대하여 Hieltijes and Lijklema 방법에 의해 Adsorbed-p, Nonapatite inorganic-P(NAI-P), Apatite-p, Organic-P로 구분하여 분석하고, 총인(Total Phosphorus)을 Standard Methods에 따라 Persulfate digestion후 0.45 m membrane 여지 여과하여 여액에 대해 PO3-4-P의 농도를 Ascorbic Acid 법으로 측정한 결과, NAI-P가 가장 큰 비율을 차지하였고, 부원료로 첨가된 금속 양이온 중 Fe3-이온이 흡착에 기여하는 정도가 가장 큰 것으로 평가되었다.다당류 T-AS의 보체 활성화 기작은 classical과 alternative complement pathway의 양 경로를 통해 활성화 되었다. T-AS 분획은 mouse내의 특정 혈청단백을 증가시켰으며, 항체 생성능의 증가가 관찰되어 effect T 세포의 활성화가 나타나고 있음을 알 수 있었다. T-AS는 생체내 투여시에 대식세포의 탐식능이 증진되었으며, 대식세포 기능 저해제에 의한 대식세포의 기능 저해 현상이 회복되었다. 이와 같은 결과들로부터, T-AS의 항암 활성은 활성

  • PDF

Mineralogical Characteristics of Tosudites from the Sungsan and Bubsoo Mines, Korea (성산광산과 법수광산에서 산출되는 토수다이트의 광물학적 특성)

  • Cho, Hyen-Goo;Kim, Won-Sa
    • Journal of the Mineralogical Society of Korea
    • /
    • v.6 no.1
    • /
    • pp.17-26
    • /
    • 1993
  • Mineralogical characteristics of tosudite from the Sungsan and Bubson mines were studied and correlated using X-ray diffraction analysis, chemical analysis and electron microscopy. Tosudite occurs as an alteration product of Cretaceous volcanoclastic rocks in both mines. It is associated with microcrystalline quartz, dickite, illite/smectite or mica/smectite mixed-layer mineral. It forms cryptocrystalline aggregates with flaky habit. XRD analysis suggests that tosudite is an 1:1regularly interstratified dioctahedral smetite/dioctahedral chlorite. Bubsoo tosudite has more(00ℓ ) reflections and more periodice stacking sequence than Syngsan tosudite. Chemical analysis shows that tosudite is a Li-bearing aluminous 1:1 regularly interstrattified mineral composed of K-bedellite and donbassite. Cookeite component may be present in the chlorite layer. Bubsoo tosudite is more Al in tetrahedral site and Ca in interlayer, but less Al in octahedral site than Sugsan tosudite. Tosudite may be formed as the intermediate alteration products, forming after muscovite and before illite/smectite or mica/s$^{\circ}C$mectite, with the range from 100 $^{\circ}C$ to 360 ~ 480 $^{\circ}C$. The hydrothermal solution forming tosudite may be acidic solution with high activities of Si and Al.

  • PDF

Occurrence of Clay Minerals from the Bobae Pottery Stone Mine in Pusan (부산 보배도석광산에서 산출하는 점토광물의산상)

  • Hwang, Jin-Yeon;Kim, Kwang-Hye;Jeong, Yoon-Yeong
    • Journal of the Mineralogical Society of Korea
    • /
    • v.6 no.1
    • /
    • pp.27-37
    • /
    • 1993
  • The clay minerals such as sericite, pyrophyllite, chlorite and smectite abundantly occur in the Bobae pottery stone mine in Pusan. In this study, the processes which are responsible for the formation of these minerals were studied by examing their occurrence and mineralogical properties. The so-called pottery stone of this mine is characterized by the predominance of sericite and quartz. The sericite of the pottery stone is mostly $2M-{1}$ type. And many of quartz particles are smaller than a few micron in diameter. The pottery stone also contained a small amount of pyrophyllite and muscovite. The pottery stone deposit occurs within the Cretaceous rhyodacite and is particularly well developed near the contact with the quartz porphyry which intrudes the rhyodacite. The fact implies that the pottery stone is the product of hydrothermal alteration of the rhyodacite by the intrusion of quartz porphyry. The pottery stone was formed by the alteration that accompanies the dissociation of feldspar and chlorite in parent rocks and subsequent formation of sericte and quartz. Smectite, laumontite and kaolinite occur locally within the altered rocks. These minerals were formed after formation of pottery stone. It is noteworthy that beidellite occurs as a pink-colored clay from the altered rocks in the mine.

  • PDF

Li-bearing Tosudite from the Sungsan Mine, Korea (해남 성산광산에서 산출되는 함리튬 토수다이트)

  • Cho, Hyen-Goo
    • Journal of the Mineralogical Society of Korea
    • /
    • v.4 no.1
    • /
    • pp.1-10
    • /
    • 1991
  • Tosudite from the Sungsan mine, Korea is an alteration product of rhyolitic tuff in the cretaceous Hwangsan Formation. It is associated with illite, dickite, nacrite or quartz and also found in the cavities of black claystone. X-ray diffraction and chemical analyses show that the Sungsan tosudite is a lithium-bearing aluminous 1:1 regularly interstratified mineral of di, dioctahedral chlorite and smectite. Its structural formula is $(K_{0.73}Na_{0.02}Ca_{0.07})(Si1_{13.23}Al_{2.77})(Li_{0.52}Mg_{0.08}Mn_{0.01)Fe^{3+}_{0.07}Al_{12.33})O_{40}(OH)_{20}$ and it suggests that Sungsan tosudite consists of regularly interstratified Li-donbassite and beidellite. DTA and TG curves as well as IR absorption data also support such a result. Temperature of formation of tosudite is inferred to be between $110{\circ}$ and $270{\circ}C$.

  • PDF