• The Korean Journal of Blood Transfusion
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• v.29 no.3
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• pp.310-319
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• 2018

Background: Research on next-generation sequencing (NGS)-based HLA typing is active. To resolve the phase ambiguity and long turn-around-time of conventional high resolution HLA typing, this study developed a NGS-based high resolution HLA typing method that can handle large-scale samples within an efficient testing time. Methods: For HLA NGS, the condition of nucleic acid extraction, library construction, PCR mechanism, and HLA typing with bioinformatics were developed. To confirm the accuracy of the NGS-based HLA typing method, the results of 192 samples HLA typed by SSOP and 28 samples typed by SBT compared to NGS-based HLA-A, -B and -DR typing. Results: DNA library construction through two-step PCR, NGS sequencing with MiSeq (Illumina Inc., San Diego, USA), and the data analysis platform were established. NGS-based HLA typing results were compatible with known HLA types from 220 blood samples. Conclusion: The NSG-based HLA typing method could handle large volume samples with high-throughput. Therefore, it would be useful for HLA typing of bone marrow donation volunteers.

• Asia-Pacific Journal of Business Venturing and Entrepreneurship
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• v.13 no.6
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• pp.177-189
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• 2018

Business environment is always full of challenges. Despite various strategic efforts, there are so many failure cases of misfit. With the weaker resource base and institutional foundation, startup firms find it more difficult to find the right spot in the stiff competition. In the middle of evolutionary process, the startup firms need proper strategies meeting the differential challenges along the multiple stages of growth. Following the idea of product life cycle, this study applies the four stages of growth-startup, initial growth, accelerated growth, matured, and decliing. The next step for the startup manager is meeting each stage of growth with proper strategic efforts, including strategy, structure, decision-making pattern, and control method. When the knowledge factor is introduced, there is a potential for higher performance. Based on the 'Detailed Survey on Startup Ventures in 2017,' this study explores the impact of the government subsidy program on the firm competitiveness and performance-along the four stages of growth. In each stage, the strategy factors showed differential impact.

• Journal of the Korea Institute of Information Security & Cryptology
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• v.29 no.4
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• pp.859-866
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• 2019

Cybersecurity attack targeting a specific user is rising in number, even enterprises are trying to strengthen their cybersecurity. Network segmentation environment where public network and private network are separated could block information coming from the outside, however, it is unable to control outside information for business efficiency and productivity. Even if enterprises try to enhance security policies and introduce the network segmentation system and a solution incorporating CDR technology to remove unnecessary data contained in files, it is still exposed to security threats. Therefore, we suggest a system that uses file format conversion to transmit a secure file in the network separation environment. The secure file is converted into an image file from a document, as it reflects attack patterns of inserting malicious code into the document file. Additionally, this paper proposes a system in the environment which functions that a document file can keep information for incident response, considering forensic readiness.

• Journal of Korea Water Resources Association
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• v.52 no.7
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• pp.463-473
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• 2019

This study compared the characteristics of the optimization technique and the water supply and demand forecast using K-WEAP (Korea-Water Evaluation and Planning System) model and MODSIM (Modified SIMYLD) model considering wtaer supply priority. Currently, The national water resources plan applied same priority for municipal, industrial and agricultural demand. the K-WEAP model performs the ratio allocation to satisfy the maximum satisfaction rate, whereas the MODSIM model should be applied to the water supply priority of demands. As a result of applying the priority, water shortage decreased by an average of $1,035,000m^3$ than same prioritized results. It is due to the increase of the return flow rate as the distribution of Municipal and industrial water increases. Comparing the analysis results of K-WEAP and MODSIM applying the priorities, the relative error was within 5.3% and the coefficient of determination ($R^2$) was 0.9999. In addition, if both models provide reasonable water balance analysis results, K-WEAP is superior to GUI convenience for model construction and data processing. However, MODSIM is more effective in simulation time efficiency. It is expected that it will be able to carry out analysis according to various scenarios using the model.

• Journal of the Korean Society of Surveying, Geodesy, Photogrammetry and Cartography
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• v.37 no.3
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• pp.109-118
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• 2019

Road information is one of the most significant geospatial data for applications such as transportation, city planning, map generation, LBS (Location-Based Service), and GIS (Geographic Information System) database updates. Robust technologies to acquire and update accurate road information can contribute significantly to geospatial industries. In this study, we analyze the limitations of ACO (Ant Colony Optimization) road extraction, which is a recently introduced object-based road extraction method using high-resolution satellite images. Object-based ACO road extraction can efficiently extract road areas using both spectral and morphological information. This method, however, is highly dependent on object descriptor information and requires manual designations of descriptors. Moreover, reasonable iteration closing point needs to be specified. In this study, we perform improved ACO road extraction on VHR (Very High Resolution) optical satellite image by proposing an optimization stopping criteria and descriptors that complements the limitations of the existing method. The proposed method revealed 52.51% completeness, 6.12% correctness, and a 51.53% quality improvement over the existing algorithm.

• Environmental and Resource Economics Review
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• v.28 no.2
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• pp.307-326
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• 2019

The electric vehicle is a representative measure to reduce greenhouse gas and local air pollutants in the transportation sector. Most countries provide purchase subsidies and tax reductions to promote electric vehicle sales. The electric vehicles have been considered as zero-emission vehicles(ZEV) in light of the fact that there has been no pollutant emission during driving. However, recent studies have pointed out that the pollutant emitted from the process of generating electricity used for charging the electric vehicles need to be treated as emissions of the electric vehicles. Furthermore, the environmental benefits of electric vehicle replacing the internal combustion vehicle vary with the power mix. In line with the recent studies, this study analyzes the impact of electric vehicles based on the current power mix and future energy transition scenarios in Korea. To estimate the precise air pollutants emission profile, this study uses hourly electricity generation and TMS emission data for each power plant from 2015 to 2016. The estimation results show that the electric vehicles under the current power mix generate the environmental benefits of only -0.41~10.83 won/km. Also, we find that the environmental benefit of electric vehicle will significantly increase only when the ratio of the coal-fired power plant is reduced to a considerable extent.

• Journal of Digital Convergence
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• v.17 no.6
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• pp.193-200
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• 2019

This study analyzes the current status and performance of regional industrial policy in the face of the weakening industrial competitiveness under the global trend of the 4th industrial revolution and suggests the policy direction that regional industrial policy as a new national growth strategy. This study focuses on the suggestion of new regional industrial policy framework under new policy environment based on literature review. We propose a new industrial policy framework that simultaneously pursues equality between regions and efficiency within the region at the same time. As a core policy recommendation, we suggest first, establishing the region-centered industrial policy governance, second, strengthening planning function of local government through human resource development and institutionalized national government consulting, and the third, constructing lifestyle industry-ecosystem based on cultural asset and identity of region, fourth, utilizing Smart City, as a platform for participatory innovation, entrepreneurial and capital attraction, and cultivating new industry based on public procurement and data. Main suggestions of this study would be a new guideline coping with the declining industrial competitiveness and the Fouth Industrial Revolution. Details would be necessary.

• KIPS Transactions on Software and Data Engineering
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• v.8 no.1
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• pp.1-12
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• 2019

In this paper, it was found that most of the machinery facilities problems generated by clients could be prevented in advance by systematically managing the mechanical equipment production process of small and medium enterprises (SMEs) that produce machinery facilities. Major point of this process is to establish an operating system that corresponds to reality of facility manufacturers as it represents 63% of machinery facilities problems that occur in customers and is a task that needs to be solved most intensively. Technical issues account for 23% of machinery facilities problems occurring at the client's companies and should be approached from a long-term perspective as they are directly related to the technical capabilities of the manufacturers. Organizational problems account for 14% of machinery facilities problems occurring in customer companies, and can change depending on the relationship of members and the nature of the human being, such as morality and motivation. In addition, we propose the establishment of an Internet-based production process management platform for smooth and efficient transfer of information between customers and machinery facilities manufacturers.

• Journal of the Korean Society of Surveying, Geodesy, Photogrammetry and Cartography
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• v.36 no.6
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• pp.457-467
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• 2018

Currently, the regulation and rules for public surveying and the UCPs (Unified Control Points) adapts those of the triangulated traverse surveying. In addition, such regulations do not take account of the unique characteristics of GNSS (Global Navigation Satellite System) surveying, thus there are difficulties in field work and data processing afterwards. A detailed procesure of GNSS processing has not yet been described either, and the verification of accuracy does not follow the generic standards. In order to propose an appropriate procedure for field surveys, we processed a short session (30 minutes) based on the scenarios similar to actual situations. The reference network in Seoul was used to process the same data span for 3 days. The temporal variation during the day was evaluated as well. We analyzed the accuracy of the estimated coordinates depending on the parameterization of tropospheric delay, which was compared with the 24-hr static processing results. Estimating the tropospheric delay is advantageous for the accuracy and stability of the coordinates, resulting in about 5 mm and 10 mm of RMSE (Root Mean Squared Error) for horizontal and vertical components, respectively. Based on the test results, we propose a procedure to estimate the daily solution and then combine them to estimate the final solution by applying the minimum constraints (no-net-translation condition). It is necessary to develop a web-based processing system using a high-end softwares. Additionally, it is also required to standardize the ID of the public control points and the UCPs for the automatic GNSS processing.

• 재활복지
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• v.22 no.3
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• pp.23-39
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• 2018

The fourth industrial revolution and technological innovation will make the job factor of people with disabilities complicated and difficult. Thus, this study analyzed the technical factors influencing the job structure and tried to find a way to develop the job of the people with disabilities in response to the 4th Industrial Revolution by changing the labor market and changing the trend of the employment by industry. The methods for this study are literature research and FGI. First, technological factors affecting the job structure of the Fourth Industrial Revolution are artificial intelligence, Internet and networking of things, 3D printing, big data, Second, technological innovation due to the industrial revolution was a major factor in the job structure. As the industrial revolution and technological innovation progressed, the job structure shifted rapidly from the manufacturing industry to the service industry, Third, as the measures of the 4th Industrial Revolution and the change of the job structure, it is necessary to make preemptive investment for the development of competency to cope with technological innovation, Finally, in order to respond to the Fourth Industrial Revolution and the rapidly changing technological innovation, the basic data of people with disabilities should be able to be big data.