• Journal of The Korean Association For Science Education
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• v.35 no.4
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• pp.691-707
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• 2015

This study aims to develop biology teachers' education program based on argumentation activity about core concepts of evolution and to analyze the characteristics of core concepts of evolution learned during the program. The eight core concepts of evolution in this study were variation, heritability of variation, competition, natural selection, adaptation, differential reproductive rate of individuals, changes in genetic pool within a population, and macroevolution. The performances of teachers participating in the program were compared before and after argumentation activities; consisting of seven sessions on the eight core concepts of evolution. The process of the program was specially designed by learning cycle model for teacher education, consisting of seven phases: identification of the task, production of a tentative argument, small group's written argument, share arguments with the other groups, reflective discussion, final written argument, and organization by an instructor. Participants in the study were two pre-service biology teachers and four in-service biology teachers. The results suggest that biology teachers reduced the teleological explanation for biological evolution and improve its adequacy after the intervention. Teachers lacked the opportunity to discuss variation, heritability of variation, competition, and macroevolution because science textbooks lack information on the concepts of biological evolution. The results of this study suggest that because the argumentation program developed for teachers helps to improve understanding the concepts of evolution and to reduce inadequate conceptions in biology, teacher education programs using argumentation activity and eight core concepts of evolution will play a role for efficient evolution education for biology teachers.

• Korean Journal of Organic Agriculture
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• v.29 no.1
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• pp.97-109
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• 2021

Plant parasitic nematodes are causing significant damage in crop production. There is a need to develop eco-friendly nematicide that reduces the damage of nematode and has little effect on the environment and human. In this study, we have isolated a substance having nematicidal activity from Ginkgo biloba L. outer seedcoat. Studies of G. biloba L. outer seedcoat are insufficient compared to the seed and leaves due to their odor and toxicity. The dried G. biloba L. outer seedcoat was extracted with dichloromethane:methanol (1:1) and fractionated into hexane, ethyl acetate and H₂O. Four steps TLC were performed from EtOAc fraction to purely isolate GB4-3 with nematicidal activity. To compare nematicidal activity, G. biloba L. seedcoat methanol extract and purified GB4-3 were investigated in terms of treatment concentration and time. As a result, the nematicidal activity increased with concentration and time. In the place treated with 20 ㎍/mL of crude G. biloba L. seedcoat MeOH extract, strong activity appeared after 12 hours, and 46% nematicidal activity shown after 18 hours. About 69% of nematicidal activity was confirmed in the place where GB4-3 purified from outer seedcoat was treated with 20 ㎍/mL, and the possibility of development as nematicide was very high. This study could be used as a basic data for the development of a nematode preparation from G. biloba L. outer seedcoat.

• Food Engineering Progress
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• v.23 no.1
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• pp.62-68
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• 2019

In this study, the physical and sensorial properties of the meat analog were studied for the purpose of improving sensory preference and mimicking animal meat. The meat analog was made with different types of liquid materials such as oil, water, lecithin, polysorbate 80, or the emulsion of these components. At the aspect of density, the sample mixed with oil was higher than the sample mixed with water. Cooking loss value was higher at the sample with water than the sample with oil and this was the result opposite to the liquid holding capacity analysis. Also, texture profile analysis result showed that the samples with medium chain triglycerides (MCT) oil only showed the highest values in all attributes except for adhesiveness. Principal component analysis was carried out to analyze sensorial properties and it showed that the overall acceptance was high when the juiciness and softness increased. This result was highly related with the addition of emulsion. Therefore, emulsion technology can be a good candidate for improving the quality of meat analog and for mimicking the taste of animal meat.

• Journal of the Society of Cosmetic Scientists of Korea
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• v.47 no.2
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• pp.123-131
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• 2021

In this study, we investigated the biological functions of Grateloupia elliptica (G. elliptica) fermented with Aureobasidium pullulans (A. pullulans). Total phenolic contents (TPC) of the hot-water extract of the fermented G. elliptica increased 2.7 folds than that of the non-fermented G. elliptica. Furthermore, total flavonoid contents of both the hot-water extract and the ethanol extract increased maximum 2.4 folds amounts than non-fermented G. elliptica extracts.HaCaT cells were induced inflammation treated with LPS (1 ㎍/mL) or H₂O₂ (1mM) and examined with 100 ㎍/mL of G. elliptica extracts. The extraction of the fermented G. elliptica increased HaCaT cell proliferation in the maximum 10% than non-fermented G. elliptica extraction. Furthermore, investigating changes in protein expression associated with inflammation resulted in a significant reduction in the expression of cyclooxygenase-2 and 70 kDa heat shock proetin. Conclusively, the extracts of G. elliptica fermented with A. pullulans have bioactive functions both anti-oxidant to protect environmental stresses and anti-inflammation activity. Hence, G. elliptica fermented with A. pullulans would be a good natural resource as bioactive ingredients for cosmetics. Therefore, G. elliptica fermented with A. pullulans is useful as a astringent material with anti-inflammatory skin.

• Journal of the Society of Cosmetic Scientists of Korea
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• v.47 no.4
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• pp.317-331
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• 2021

Essential oil is a volatile substance obtained by physically obtaining fragrant plant materials made by one single plant and plant species, and is widely used for cosmetics, fragrances, and aroma therapy due to its excellent preservation, sterilization, and antibacterial effects. When essential oil would undergo the extraction and concentration processes, the agricultural chemicals thereof would be extracted and concentrated only to be harmful to the human body. This study analyzes 320 residual agricultural chemicals concentrated in the essential oil, and to this end, LC-MS/MS and GC-MS/MS are used, while the freezing process is applied instead of the conventional refining process hexane, to improve the preprocessing method. As a result of analyzing the essential oil, such ingredients as chlorpyrifos, piperonyl butoxide and silafluofen have been detected in Basil oil and Clove leaf oil. Hence, it is perceived that the residual agricultural chemicals should continue to be monitored for the essential oil.

• Journal of agriculture & life science
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• v.50 no.2
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• pp.117-124
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• 2016

This study was estimated the effect of environmental factors and each of them on auction price of Hanwoo calves. The auction prices of Hanwoo calves(19,592head) registered pedigree were sampled in Gyeongsangnam-do from 2014 to 2015. The environmental factors were highly(p<0.01) affect to the auction price of Hanwoo calves. With the analysis of contribute factor used the semi-partial correlation, the value of regression equation(Adj R-Square) was 0.701. The semi-partial correlation values of sex, auction body weight, auction age, auction year, auction season, and auction area were 0.11563, 0.20013, 0.02823, 0.10727, 0.00330 and 0.02963, respectively. And the highest contribution factor was body weight, and then, followed sex, auction year, auction area and auction age. In conclusion, it could be suggested that Hanwoo calf farmer should improve calf body weight to increase auction price by not only breeding, but also optimal management. Additionally, it is expecting in the future that competitiveness and income of farmers will be affected deeply by the holding and producing of predominant genes which is coincidence with breeding principles. However, further study should be conducted for the better understand caused by the limit of previous studies which was estimated the correlations of auction price and each factors.

• Korean Medical Education Review
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• v.8 no.1
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• pp.1-11
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• 2006

의사는 인간의 생명을 구하는 권한이 있으니까 마치 생명을 죽이는 권한도 포함된 것 같은 생각에 그야말로 막강한 권한을 가진 것 같이 보인다. 오늘의 한국에서는 과거와 달리 의사의 사회적 위상에 많이 떨어져 있지만 아직도 미국이나 독일 같은 선진 사회에서 의사의 위상은 준신에 가깝게 높고 그의 말과 판단이라면 비록 건강에 관한 이슈뿐만 아니라 삶에 대한 지혜로도 존중되고 수용된다. 의사의 사회적 위상이 높아진 것은 의학이라는 특수한 학문과 이와 연결된 의술의 그동안의 엄청난 발달과 무관하지 않다. 역사적으로 보면 고대 희랍시대부터 의학은 인간의 질병을 고치고 생명을 건강하게 보존하는 특별한 지식 그리고 이 지식을 기반으로 응용되는 치료기법으로 기예 (techne)라는 존칭으로 불리었다. 즉, 건강의 회복이라는 실질적인 목적을 가진 지식과 테크닉을 합친 이른바 귀중한 실천 (praxis)이다. 의학에 대한 낙관적인 전망은 시대와 문화가 바뀌면서 또한 의학 자체가 좀 더 발달하면서 도전을 받는다. 20세기에 들어서서 인간의 생명을 위협하고 또 고통을 주는 질병의 종류와 양상이 변하고, 의 과학이 앞으로 인류의 병들을 퇴치시킬 수 있다는 기대에 차질이 생기게 되었다. 미국 같은 선진국에서는 일찍이 1960년도 말부터 의학교과목 개혁의 일환으로 인문학의 과목들을 같이 가르치기 시작했다. 대표적인 과목들이 윤리학, 철학, 역사, 문학 등이다. 인문학의 보강은 의학과 기술과 인간성의 연결을 위해 의사들이 쓸 수 있는 인지적 도구 (cognitive tools)를 갖추게 하는 목적에서이다. 인문학의 도입으로 의사들이 인간의 삶을 좀 더 깊게 이해하고 풍부한 인간성으로 지식과 기술을 환자에게 적용할 수 있기 위해 각자의 마음과 머리 속에 포용통합능력을 발달시키자는 데 있다. 즉 의사들의 의식과 자유로운 상상력이 확장되면서 새로운 정체성을 갖게 되는 것을 바라는 것이다. 선진국의 의학교육에서 이 같은 교육이 좋은 의사를 만든다는 신념을 굳혀가고 있다. 성과를 증명하는 연구결과가 없어 아직도 회의적인 반응도 있으나 이와 같은 교육이 윤리적 상황에 대한 예민도를 높이는 것은 확실하다. 연세대학교 의과대학은 기독교 이념이 기본 교육철학이다. 인간성을 강조하고 의사들이 자신의 인간성을 개발 강화하는 교육이 하나님의 사랑을 의사 지신의 인간성과 그의 인간애로 내재화 시킬 수 있다면 그리스도의 정신을 의학과 의술에 연결시키는 고귀한 목적을 이룰 수 있는 길이라고 생각한다.

• Journal of Korean Academy of Nursing
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• v.22 no.3
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• pp.389-406
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• 1992

This study was designed to identify nursing students' attitudes toward life through a Q-methodology. A Q-sample was formed through a review of the literature and interviews(n＝160)l The final Q-sample consisted of 37 statements out of an initial 100 statements after consultation with an expert panel and pilot testing. The P-sample consisted of 14 university nursing students and 27 junior college nursing students, which was selected by convenience sampling method. Data were analyzed by the Q-analysis method. The correlation between type 2 and type 3 was relatively high (r＝0.539) ; that between type 1 and type 3 was lowest (r＝0.014). The first type of attitude was the “rational utilitarian” type. Students in this type valued life relative to the quality of life. They agreed with euthanasia and artificial abortion if the quality of life was threatened. The criteria for their judgement were scientific knowledge and rationality. The second type of attitude was the “Christian deontologic” type. These students appreciated the sanctity of life according to Christian dogma. They disagreed with euthanasia and artficial abortion. And they disagreed strongly that life should be created by scientific development, because only God creates life. The third type of attitude was the “unconditional deontologic” type. These students agreed with the sanctity of life, not from Christian belief but from belief in the sanctity of life. The final type of attitude was the “prima facie(conditional) deonologic” type. These students appreciated the value of life and humanity. They expressed concern for others' life and suffering. They do not want to afflict others with their own miseries. This group showed a dual value system toward themselves and others. So they experience conflict between their concern for their on and others' conditions. These nursing students' values may have been influenced by their clinical experience in hospitals and other nursing fields. Through this study, we may realize the importance of education in nursing ethics for discussion of ethical conflicts and to support ethical nursing practice.

• Journal of Life Science
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• v.14 no.2
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• pp.209-214
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• 2004

Cytotoxic anticancer chemotherapeutic agents generally produce severe side effects, while reducing host resistance to cancer and infections, especially through the destruction of lymphoid and bone marrow cells. In this study, we have investigated the effect of chitosan on cytotoxic activity against cancer cells and life span in mice. The direct cytotoxicity of chitosan or chitosan-combinated chemotherapeutic agents for tumor cells was observed. In addition, the effect of life span extention was counted on sarcoma 180 mice injected with chitosan-combinated mitomycin C. The effect of growth inhibion for cancer cells, K562 and Yac-1 was shown in the cytotoxicity test of chitosan or chitosan-combinated chemotherapeutic agents. Also, the effect of life span extension was observed on sarcoma 180 mice injected with chitosan-combinated mitomycin C. Our results suggest that life span extension in sarcom 180 mice exposed with chitosan-combinated chemotherapeutic agents showed the probability of its usefulness for cancer therapy if more research results were accumulated.

• The Journal of the Convergence on Culture Technology
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• v.5 no.4
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• pp.171-181
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• 2019

In this article, we examined designer babies and bioethics, and we reviewed how Anna argued that she had the rights to her body through trial with parents. No matter what purpose a cloned human or designer baby was born with, it is worth being respected as the birth itself. After learning the secrets of his birth in Jodie Picoult's My Sister's Keeper, which is based on a designer baby, Anna falls into confusion of identity and sues parents who decide to transplant organs regardless of Anna's will. Anna argues that she has the right to make decisions about her own body and that even her parents can't disregard her opinions. Scientists should stop their research if using biotechnology to reproduce humans, such as designer babies and cloned humans, can destroy the natural order.