• Bulletin of the Korean Chemical Society
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• v.20 no.2
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• pp.237-240
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• 1999

• 대학교육
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• s.177
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• pp.86-92
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• 2012

• Journal of Physiology & Pathology in Korean Medicine
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• v.33 no.2
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• pp.158-162
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• 2019

This study is to show the clinical effect of additional CP Pharmacopuncture on hypoesthesia of lower limb which was occurred by laminectomy. The patients were treated using CP Pharmacopuncture, and other treatments including acupunture, moxibustion and herbal medication. The effect of treatment was measured by Numeric Rating Scale(NRS) and American Spinal Injury Association(ASIA) scale. After treatment, NRS was gradully reduced and ASIA scale's score was incresed. These results suggest that CP Pharmacopuncture might be a possible therapeutic option for hypoesthesia of lower limb which was occurred by laminectomy.

• Proceedings of the Korea Information Processing Society Conference
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• 2020.11a
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• pp.655-658
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• 2020

최근 IT 기술의 발달로 태블릿, 스마트폰과 같은 다양한 디바이스로 손쉽게 음악을 감상할 수 있다. 하지만 최근 이런 기술 발달과는 다르게 사용자가 원하는 음악을 검색하는 방법은 고전적인 형태에서 벗어나지 않고 있다. 기존 음악 검색 방법은 텍스트 기반, 내용 기반, 소비자 감성 기반의 음악 추천 검색 방법이 있으며 저장된 메타 데이터를 이용하여 사용자의 질의에 대한 결과만 제공할 뿐 사용자의 경험 정보를 고려하지 않는다. 그리고 기존 플랫폼들은 사용자가 최근 많이 들은 가수, 장르, 분위기를 종합하여 사용자에게 어울리는 음악을 추천을 할 뿐 사용자의 경험정보를 고려하여 음악을 추천하지는 않는다. 본 논문에서는 사용자의 경험 정보를 활용하여 사용자 맞춤형 음악 추천 시스템을 제안한다. 본 시스템은 사용자의 현재 기분 정보, 주변 날씨 정보 등을 입력 받는다. 이후, 경험 정보를 기반으로 결정 트리를 통해 사용자 요구 기반의 음악 추천 시스템을 구축하였다.

• Herbal Formula Science
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• v.31 no.4
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• pp.265-281
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• 2023

Objectives : Ukgan-san plus Citri Pericarpium and Pinelliae Rhizoma (UCP) is used as a traditional herbal formula in Korea and Japan for treatment of fever, fever-induced convulsions, and liver dysfunction and so on. In this study, we investigated the cytoprotective effect and underlying mechanism of UCP against oxidative stress induced by cotreatment of arachidonic acid (AA) and iron. Methods : To evaluate the hepatoprotective effects of UCP against AA + iron-induced oxidative stress in HepG2 cell, cell viability and changes on apoptosis-related proteins were assessed by MTT and immunoblot analyses. The changes in intracellular reactive oxygen species (ROS), glutathione (GSH), and mitochondrial membrane permeability (MMP) were investigated against to the oxidative stress. Furthermore, to verify underlying molecular mechanism, NF-E2-related factor 2 (Nrf2) and its downstream target genes were examined by immunoblot analysis. Results : Treatment of UCP increased the cell viability and altered the expression levels of apoptosis-related proteins such as PARP, caspase-9, caspase-3, Bcl-2. UCP also inhibited the GSH depletion, excessive ROS production and mitochondrial dysfunction induced by AA + iron. In addition, the Nrf2 and the Nrf2 target genes activation were increased by UCP. Conclusions : These results indicated that UCP has the ability to protect against oxidative stress-induced hepatocyte damage, which may be mediated with Nrf2 pathway.

• Journal of Environmental Health Sciences
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• v.47 no.6
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• pp.521-529
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• 2021

Background: The coronavirus disease (COVID-19) has caused changes in human activity, and these changes may possibly increase or decrease exposure to fine dust (PM_2.5). Therefore, it is necessary to evaluate the exposure to PM_2.5 in relation to the outbreak of COVID-19. Objectives: The purpose of this study was to compare and evaluate the exposure to PM_2.5 concentrations by the variation of dynamic populations before and after the outbreak of COVID-19. Methods: This study evaluated exposure to PM_2.5 concentrations by changes in the dynamic population distribution in Guro-gu, Seoul, before and after the outbreak of COVID-19 between Jan and Feb, 2020. Gurogu was divided into 2,204 scale standard grids of 100 m×100 m. Hourly PM_2.5 concentrations were modeled by the inverse distance weight method using 24 sensor-based air monitoring instruments. Hourly dynamic population distribution was evaluated according to gender and age using mobile phone network data and time-activity patterns. Results: Compared to before, the population exposure to PM_2.5 decreased after the outbreak of COVID-19. The concentration of PM_2.5 after the outbreak of COVID-19 decreased by about 41% on average. The variation of dynamic population before and after the outbreak of COVID-19 decreased by about 18% on average. Conclusions: Comparing before and after the outbreak of COVID-19, the population exposures to PM_2.5 decreased by about 40%. This can be explained to suggest that changes in people's activity patterns due to the outbreak of COVID-19 resulted in a decrease in exposure to PM_2.5.

• The Journal of Internal Korean Medicine
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• v.42 no.2
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• pp.165-174
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• 2021

This study reported on the effect of traditional Korean medicine on ataxia, gait disturbance, tremor, and dizziness with cerebellar atrophy. The patient was treated with traditional Korean medicines, such as acupuncture, moxibustion, and herbal medicine (Kuibiondam-tang-gami). The effectiveness of the treatment was evaluated with the scale for the assessment and rating of ataxia (SARA). After treatment, the symptoms had improved. The SARA score decreased by 18 points after Korean medicine treatment. According to this study, traditional Korean medicine can be effective to treat ataxia, gait disturbance, tremor, and dizziness in patients with cerebellar atrophy.

• Journal of Korean Medicine Rehabilitation
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• v.29 no.3
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• pp.165-172
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• 2019

The objective of this study is to propose postoperative rehabilitation for foot fracture in Korean Medicine and to report its effectiveness. There were three patients who were got foot fracture surgery received korean medicine with acupuncture, herbal medicine, cupping and exercise treatment. Patients were evaluated numeric rating scale (NRS), range of motion (ROM), American Orthopaedic Foot and Ankle Society (AOFAS) ankle hindfoot score, foot function index (FFI) and EuroQol-5 dimension (EQ-5D) index. Case 1 and 2 were improved NRS from 6 to 3. Case 3 was improved NRS from 5 to 2. These cases were improved ROM in all directions, AOFAS score, FFI, EQ-5D and walking status. This study suggest that Korean medicine rehabilitation could be effective for patients who have received foot fracture operation.

• Journal of Korean Society on Water Environment
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• v.35 no.4
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• pp.352-361
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• 2019

The purpose of this study is to analyze the characteristics and correlations of the Yeongcheon Lake in order to reduce the occurrence of harmful cyanobacteria. In this study, we investigated the water quality and phytoplankton of the lake from May to November in 2017. Correlation and data mining analyses were performed to analyze the relationship between the two factors. The water temperature was lowest at the point where the Yeongcheon Lake inflow occurs at Imha Lake. It was highest at the point where the outflow occurs to Angye Lake. The pH was also highest at the outflow point, but in the case of DO, it was highest at the midpoint between the inflow and outflow. The main cyanobacteria that emerged during the study period were Oscillatorialimosa, Microcysti saeruginosa and Aphanizomenon flos-aquae. As a result of correlation analysis, the water temperature, inflow, COD loading, TOC loading at the inflow point of the Yeongcheon Lake were the items that were related to the harmful cyanobacteria. The data mining analysis indicated that the TP loading and harmful cyanobacteria in the inflow point of the Yeongcheon Lake were influential on the detrimental cyanobacteria in the Yeongcheon Lake outflow point. When the TP loading was less than 39.0 kg/day at the inflow site, it was expected that the amount of harmful cyanobacteria could be maintained below 10,000 cells/mL.

• The Journal of Churna Manual Medicine for Spine and Nerves
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• v.17 no.1
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• pp.21-33
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• 2022

Objectives To assess the effectiveness of Chuna manual therapy in patients with Tourette's syndrome. Methods We queried nine electronic databases using the keywords "Tourette's Syndrome" and "tuina OR chuna" to identify RCTs that investigated the effectiveness of Chuna manual therapy in patients with Tourette's syndrome. Results Thirteen RCTs were selected according to the inclusion criteria. A systematic review showed that Chuna manual therapy can have a curative effect on patients with Tourette's syndrome. Conclusions In this study, 13 RCTs reported that Chuna manual therapy was effective for Tourette's syndrome. These findings provide a basis for its clinical use. However, all studies involved populations belonging to the same country. Many studies lacked details of the research methodology. Therefore, further studies are required to produce high-quality evidence.